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Transcriptional repressor protein
YY1 (Yin Yang 1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene. YY1 is a ubiquitously distributed transcription factor
YY1
Protein-coding gene in the species Homo sapiens
YY1-associated factor 2 is a protein that in humans is encoded by the YAF2 gene. The protein encoded by this gene interacts with YY1, a zinc finger protein
YAF2
Topics referred to by the same term
Xanth from the Xanth series YY1 or Yin Yang 1, a transcriptional repressor protein in humans that is encoded by the YY1 gene The Yin and the Yang of
Yin_yang_(disambiguation)
Region of DNA encouraging transcription
loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the enhancer
Promoter_(genetics)
Group of transposable elements
the transcription factor YY1. Younger families also have two binding sites for SOX-family transcription factors, and both YY1 and SOX sites were shown
LINE1
Process of copying a segment of DNA into RNA
loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the enhancer
Transcription_(biology)
Protein-coding gene in the species Homo sapiens
RING1 and YY1-binding protein is a protein that in humans is encoded by the RYBP gene. RYBP has been shown to interact with: Abl gene, CBX2, Caspase 10
RYBP
Family of proteins
"autoregulatory loop", which is driven by PARP1 itself and modulated by the YY1 transcription factor. While in vitro cleavage by caspase occurs throughout
Poly_(ADP-ribose)_polymerase
Protein-coding gene in the species Homo sapiens
YY1-associated protein 1 is a protein that in humans is encoded by the YY1AP1 gene. The encoded gene product presumably interacts with YY1 protein; however
YY1AP1
Protein-coding gene in the species Homo sapiens
PMID 15661747. Wang CC, Tsai MF, Hong TM, et al. (2005). "The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer
DNAJB4
Segment of nucleic acid that affects the expression of associated genes
loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the enhancer
Regulatory_sequence
Protein-coding gene in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
CBX1
DNA sequence that binds activators to increase the likelihood of gene transcription
loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the enhancer
Enhancer_(genetics)
Family of regulator genes
SAP130 SMAD2 SMAD3 SMARCA4 SMARCB1 SUPT3H TIAM1 TADA2L TAF9 TFAP2A TRRAP WDR5 YY1 and ZBTB17. C2orf16 Myc-tag C-myc mRNA "Myc". NCBI. Finver SN, Nishikura
Myc
Class of proteins
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Small_Maf
Protein-coding gene in humans
Schlisio S, Halperin T, Vidal M, Nevins JR (November 2002). "Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F
KMT5A
Campos, Brazilian astronomer at Valongo Observatory MPC · 3610 3611 Dabu 1981 YY1 Dabu County, Guangdong, China MPC · 3611 3612 Peale 1982 TW Stanton J. Peale
Meanings of minor-planet names: 3001–4000
Meanings_of_minor-planet_names:_3001–4000
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
GLI2
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ZEB2
Conversion of a gene's sequence into a mature gene product or products
loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1). One member of the dimer is anchored to its binding motif on the enhancer
Gene_expression
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
JARID2
Protein found in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
FOXA1
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ID2
Protein-coding gene in humans
components of the mammalian Polycomb complex, and with the transcription factor YY1". EMBO J. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID 10369680
Chromobox_2
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
USF1
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
GTF2E2
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Sp4_transcription_factor
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
CRX_(gene)
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
HOXA11
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
NPAS3
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
E4F1
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
EBF1
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
EMX1
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
HLF_(gene)
H. Debehogne, G. de Sanctis · 4.6 km (2.9 mi) MPC · JPL 3611 Dabu 1981 YY1 Dabu December 20, 1981 Nanking Purple Mountain DOR 14 km (8.7 mi) MPC · JPL
List of minor planets: 3001–4000
List_of_minor_planets:_3001–4000
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
SMAD6
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Nuclear_receptor_4A3
Protein molecule receiving signals for a cell
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Receptor_(biochemistry)
Family of zinc finger transcription factors
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Kruppel-like_factors
Nuclear receptor protein found in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Peroxisome proliferator-activated receptor gamma
Peroxisome_proliferator-activated_receptor_gamma
Nuclear receptor
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Liver_X_receptor
Protein
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
FOXO4
Protein coding gene in Humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
TLX1
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ZNF350
Main-belt asteroid
8° with respect to the ecliptic. Somerville was first identified as 1982 YY1 at Purple Mountain Observatory in December 1982. The body's observation arc
5771_Somerville
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
POU4F3
Mammalian protein found in Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
NFAT5
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ZNF146
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
PHF21A
8, 1984 Anderson Mesa E. Bowell · 6.6 km MPC · JPL 32770 Starchik 1984 YY1 Starchik December 23, 1984 Nauchnij L. G. Karachkina · 4.5 km MPC · JPL
List of minor planets: 32001–33000
List_of_minor_planets:_32001–33000
Protein-coding gene in the species Homo sapiens
human ST5 gene in HeLa-fibroblast hybrid cell lines mediated by YY1: evidence that YY1 plays a part in tumor suppression". Nucleic Acids Research. 24 (23):
ST5_(gene)
involves epigenetic control and multiple transcription factors. PRC1, PRC2, YY1, and Id1 play a role in the suppression of p16INK4A expression and transcription
INK4
14, 1996 Sormano F. Manca, P. Chiavenna NYS 2.9 km MPC · JPL 39735 1996 YY1 — December 20, 1996 Xinglong SCAP · 4.9 km MPC · JPL 39736 1997 AM — January
List of minor planets: 39001–40000
List_of_minor_planets:_39001–40000
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
HOXA2
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
OLIG1
Protein-coding gene in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Homeobox_protein_CDX-4
Human protein-coding gene
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
BBX_(gene)
Protein-coding gene in the species Homo sapiens
and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors". J. Biol. Chem. 277 (25): 22484–90
GABPB2
YH1 — December 21, 1995 Oizumi T. Kobayashi · 4.5 km MPC · JPL 14051 1995 YY1 — December 21, 1995 Oizumi T. Kobayashi (2076) 4.1 km MPC · JPL 14052 1995
List of minor planets: 14001–15000
List_of_minor_planets:_14001–15000
Protein found in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
SMAD2
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
HOXC6
Type of nucleic acid sequence
gene-regulation. Furthermore, SINEs frequently contain motifs for YY1 polycomb proteins. YY1 is a zinc-finger protein that acts as a transcriptional repressor
Short interspersed nuclear element
Short_interspersed_nuclear_element
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ZNF239
18, 1992 Okutama Hioki, T., Hayakawa, S. HNS 6.3 km MPC · JPL 24760 1992 YY1 — December 18, 1992 Caussols E. W. Elst · 2.9 km MPC · JPL 24761 Ahau 1993
List of minor planets: 24001–25000
List_of_minor_planets:_24001–25000
1997 Nachi-Katsuura Y. Shimizu, T. Urata · 6.8 km MPC · JPL 28009 1997 YY1 — December 21, 1997 Oizumi T. Kobayashi · 5.9 km MPC · JPL 28010 1997 YE3
List of minor planets: 28001–29000
List_of_minor_planets:_28001–29000
✗ 9.1 0.7 20.5 2.3 15.9 2.22 SSBN07: not a centaur; (U:9) MPC · JPL 2000 YY1 17 Dec 2000 M. J. Holman B. Gladman T. Grav 212 N TNO Y CEN N 63 0.5 7.9
List of centaurs (small Solar System bodies)
List_of_centaurs_(small_Solar_System_bodies)
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
TOX4
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ZNF330
Protein family
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Iroquois_homeobox_factor
motif – from protein with 100% identical DBD – in vitro [1,012] YGTWCCAYC YY1 ENSG00000100811 C2H2 ZF Known motif – High-throughput in vitro [1,013] HRWNATGGCB
List of human transcription factors
List_of_human_transcription_factors
Protein-coding gene in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ATF3
American geneticist
polycomb-associated RNAs by RIP-seq. J Zhao, T Ohsumi, ... JT Lee. Molecular Cell, 2010 YY1 tethers Xist RNA to the inactive X nucleation center. Y Jeon, JT Lee. Cell
Jeannie_T._Lee
Human chromosome
VPS37B: encoding protein Vps37b, escrt-i subunit YAF2: encoding protein YY1-associated factor 2 ZCCHC8: encoding protein Zinc finger CCHC domain-containing
Chromosome_12
Protein found in humans
against decapentaplegic homolog 3 NFKB1, NOV, RBPJ, SNW1, Ubiquitin C, and YY1. USP10. GRCh38: Ensembl release 89: ENSG00000148400 – Ensembl, May 2017 GRCm38:
Notch_1
Mammalian protein found in Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
TFAP2D
Protein-coding gene in the species Homo sapiens
2010). "The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression". Molecular and
KDM1B
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
N-Myc
Protein-coding gene in the species Homo sapiens
the transcription of ER chaperones. ATF6 has been shown to interact with YY1 and Serum response factor. Activating transcription factor GRCh38: Ensembl
ATF6
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
BHLHA9
Group of nuclear receptor proteins
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Peroxisome proliferator-activated receptor
Peroxisome_proliferator-activated_receptor
Human protein and coding gene
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
NFE2L2
Protein-coding gene in the species Homo sapiens
repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important
Histone_deacetylase_2
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
SOX17
Chemical compound
Lee SO, Brents LK, Prather PL, Safe S (July 2012). "Betulinic acid targets YY1 and ErbB2 through cannabinoid receptor-dependent disruption of microRNA-27a:ZBTB10
Betulinic_acid
Family of transcription factor protein complexes
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
NF-κB
Protein-coding gene in the species Homo sapiens
SS18, STAT3, STAT6, TAL1, TCF3, TFAP2A, TGS1, TRERF1, TSG101, THRA, TWIST1, YY1, and Zif268. GRCh38: Ensembl release 89: ENSG00000100393 – Ensembl, May 2017
EP300
Protein-coding gene in the species Homo sapiens
functionally associates with histone deacetylases and with transcription factor YY1". The EMBO Journal. 20 (17): 4814–4825. doi:10.1093/emboj/20.17.4814. PMC 125595
HDAC1
Protein-coding gene in the species Homo sapiens
Margolis DM, Somasundaran M, Green MR (Feb 1994). "Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production"
TFCP2
Class of enzymes important in regulating DNA transcription
HSP90, Ku70, NFκB, PCNA, p53, RB, Runx, SF1 Sp3, STAT, TFIIE, TCF, and YY1. The short-chain fatty acid butyric acid (butyrate), made by gut bacteria
Histone_deacetylase
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
SOX18
DNA pattern affecting anatomy development
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Homeobox
Mammalian protein found in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Androgen_receptor
Protein that initiates male sex determination in therian mammals
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Sex-determining region Y protein
Sex-determining_region_Y_protein
Control of DNA to RNA conversion in cells
loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the enhancer
Transcriptional_regulation
Mammalian protein found in humans
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
P53
Biological processes used in gene regulation
2 can also bind directly to DNA binding proteins such as Yin and Yang 1 (YY1), Rb binding protein 1 and Sp1. HDACs 1 and 2 have been found to express
Histone acetylation and deacetylation
Histone_acetylation_and_deacetylation
Protein-coding gene in the species Homo sapiens
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
ZNF274
Compounds that inhibit histone deacetylases
HSP90, Ku70, MKP-1, NF-κB, PCNA, p53, RB, Runx, SF1 Sp3, STAT, TFIIE, TCF, YY1, etc. HDIs have a long history of use in psychiatry and neurology as mood
Histone_deacetylase_inhibitor
Proteins activated by the hormone estrogen
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
Estrogen_receptor
Transcription factor gene of the forkhead box family
BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP 1 2 3 IKZF 1 2 3 ILF 2 3 Sp/KLF family KLF 1 2 3 4 5 6 7 8
FOXP2
YY1
YY1
YY1
YY1
Boy/Male
American, British, Celtic, English
Sea Friend; White
Boy/Male
Indian
A cowherd, Name of dynasty
Girl/Female
Tamil
Bright flame
Girl/Female
English American German Latin
A variant spelling of the German Earnest, meaning serious determined, earnestness or vigor, from...
Boy/Male
Indian
Wealthy
Girl/Female
Hindu
The Moon
Boy/Male
Basque, British, English, French, Latin
The Moor
Girl/Female
Tamil
Spring
Boy/Male
Indian
Rose.
Boy/Male
Muslim/Islamic
Pureness Pure
YY1
YY1
YY1
YY1
YY1