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polymerase I upstream activating factor complex". Saccharomyces Genome Database. Stanford University. Retrieved 13 August 2014. "Upstream activation factor subunit
Upstream_activating_factor
Protein that regulates the rate of DNA transcription
complex binds to promoter regions of DNA upstream to the gene that they regulate. Other transcription factors differentially regulate the expression of
Transcription_factor
An upstream activating sequence or upstream activation sequence (UAS) is a cis-acting regulatory sequence found in yeast like Saccharomyces cerevisiae
Upstream_activating_sequence
Largest structure in the nucleus of eukaryotic cells
I-associated factors and DNA-specific trans-acting factors are required. In yeast, the most important are: UAF (upstream activating factor), TBP (TATA-box
Nucleolus
Protein found in humans
capable of activating NR2A although this was not found in the hippocampus. Thus, BDNF can increase NMDA receptor activity through Fyn activation. This has
Brain-derived neurotrophic factor
Brain-derived_neurotrophic_factor
Cellular process
an upstream activating factor or UAF that associates with TATA-box binding protein and the core factor (CF). Together the two transcription factors allow
Ribosome_biogenesis
Protein-coding gene in the species Homo sapiens
Upstream stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene. The upstream stimulatory factor (USF) gene encodes a transcription
USF1
Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)
Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors
AP-1_transcription_factor
Protein that increases transcription of a gene or set of genes
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. Activators are considered to have
Activator_(genetics)
P38 mitogen-activated protein kinases
important upstream activators of this pathway are the Raf proteins (A-Raf, B-Raf or c-Raf), the key mediators of response to growth factors (EGF, FGF
Mitogen-activated protein kinase
Mitogen-activated_protein_kinase
Pdr1, Pdr3, Leu3. Gal4 recognizes genes with UASG, an upstream activating sequence, and activates them. In yeast cells, the principal targets are GAL1
Gal4_transcription_factor
Class of enzymes
stimulates glycolysis by activating phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2/3 and activating phosphorylation of glycogen
AMP-activated_protein_kinase
Mammalian protein found in Homo sapiens
Activating transcription factor 4 (tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene.
ATF4
Series of biochemical reactions
stimulation by one of the growth factors causes activation of a cell surface receptor and phosphorylation of PI3K. Activated PI3K then phosphorylates lipids
Akt/PKB_signaling_pathway
Proteins which remove GDP from GTPases
Guanine nucleotide exchange factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate
Guanine nucleotide exchange factor
Guanine_nucleotide_exchange_factor
Region of DNA encouraging transcription
of transcription factor bound to enhancer in the illustration). An activated enhancer begins transcription of its RNA before activating a promoter to initiate
Promoter_(genetics)
Protein complex
as insulin like growth factor 1 (IGF1), can activate the MAPK/ERK pathway, which can inhibit the TSC1/TSC2 complex, activating mTORC1. In this pathway
MTORC1
Mammalian protein found in Homo sapiens
the osteoblasts' surface-bound RANKL activating the osteoclasts' surface-bound receptor activator of nuclear factor kappa-B (RANK). Recent studies suggest
RANKL
DNA sequence that binds activators to increase the likelihood of gene transcription
to as transcription factors. Enhancers are cis-acting. They can be located up to 1 Mbp (1,000,000 bp) away from the gene, upstream or downstream from the
Enhancer_(genetics)
Fear Factor is an American stunt/dare game show that pits contestants against one another in a series of extreme physical and mental challenges. The series
List of Fear Factor (American TV series) episodes
List_of_Fear_Factor_(American_TV_series)_episodes
Protein that initiates male sex determination in therian mammals
theca cells). SRY initiates testis differentiation by activating male-specific transcription factors that allow these bipotential cells to differentiate
Sex-determining region Y protein
Sex-determining_region_Y_protein
Class of enzymes
by transforming growth factor-beta (TGF-beta). The most upstream stimuli that activate MAPKKK is either stress or growth factors. This includes mitogens
MAP_kinase_kinase_kinase
Class of enzymes
the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates the NF-κB transcription factor by masking
IkappaB_kinase
Molecular biology technique
behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For
Two-hybrid_screening
Type of CRISPR tool
transcriptional factors on the antibodies, the SunTag dCas9 activating complex amplifies its recruitment of transcriptional factors. In order to guide
CRISPR_activation
Control of DNA to RNA conversion in cells
transcription factor bound to an enhancer in the illustration). An activated enhancer begins transcription of its RNA before activating a promoter to
Transcriptional_regulation
Enzyme that transcribes DNA to small RNAs
TFIIIC acts as an assembly factor that positions TFIIIB to bind to DNA at a site centered approximately 26 base pairs upstream of the start site of transcription
RNA_polymerase_III
Human protein and coding gene
Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription factor that in humans is
NFE2L2
Mammalian protein found in Homo sapiens
transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor". J. Biol. Chem. 275 (17): 12470–4. doi:10
Serum_response_factor
Cell cycle regulation pathway
cytoplasm, and activating phosphatidylinositol 3-phosphates and mTOR, which can affect transcription of p70 or 4EBP1. There are many known factors that enhance
PI3K/AKT/mTOR_pathway
Protein in Homo sapiens
Synaptic Ras GTPase-activating protein 1, also known as synaptic Ras-GAP 1 or SYNGAP1, is a protein that in humans is encoded by the SYNGAP1 gene. SYNGAP1
SYNGAP1
Mammalian protein involved in blood clotting
clotting by activating Factor XII in the coagulation cascade. Also, due to the active ingredient nature of Kaolinite, the activation of the Factor XII occurs
Factor_XII
Class of proteins
function to CREM (cAMP response element modulator) and ATF-1 (activating transcription factor-1) proteins. CREB proteins are expressed in many animals, including
CREB
Sewage Treatment Plant
TGF-β ligands. Transforming growth factor-β (TGF-β) is a superfamily of cytokines that play a significant upstream role in regulating of morphogenesis
Upstream and downstream (transduction)
Upstream_and_downstream_(transduction)
Protein family
ovalbumin upstream promoter transcription factor (COUP-TFs) proteins are members of the nuclear receptor family of intracellular transcription factors. There
Chicken ovalbumin upstream promoter-transcription factor
Chicken_ovalbumin_upstream_promoter-transcription_factor
Type of DNA sequence
general transcription factor (GTF) assembly. NREs passively repress the gene, usually by inhibiting other elements that are upstream of the gene. Of the
Silencer_(genetics)
Family of transcription factors
genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as repressors:
E2F
Protein-coding gene in humans
osteoblast differentiation. Zinc finger protein 521 (ZFP521) and activating transcription factor 4 (ATF4) are cofactors of Runx2. Binding of the transcriptional
RUNX2
Protein family
binds specifically to the IRF-element (IRF-E) motifs, which is located upstream of the interferon genes. Some viruses have evolved defense mechanisms that
Interferon_regulatory_factors
Multi-protein structure
the upstream binding of growth factors (GF), either from within the cell itself or from neighboring cells. Stimulation by growth factors activates any
Cyclin_D/Cdk4
Form of eukaryotic RNA polymerase II
genes in vivo, and the lack of response to induction maps to the upstream activating sequences of these genes. Several protein members of the BRCA1-associated
RNA_polymerase_II_holoenzyme
Proteins that bind DNA
WRKY transcription factors (pronounced ‘worky’) are proteins that bind DNA. They are transcription factors that regulate many processes in plants and
WRKY_transcription_factor
DNA sequence
machinery has recently been documented in vivo showing the activation by SRF-dependent upstream activating sequence (UAS) of the human ACTB gene involved in TATA-binding
TATA_box
the cell type, and the number of activating or repressing sequences present in the regulatory domain. Activating domains, regulatory domains that promote
Artificial transcription factor
Artificial_transcription_factor
Process of copying a segment of DNA into RNA
of transcription factor bound to enhancer in the illustration). An activated enhancer begins transcription of its RNA before activating transcription of
Transcription_(biology)
Transcription is heterocatalytic function of DNA
Eukaryotic transcriptional activators have separate DNA-binding and activating functions. Upon binding to its cis-element, an activator can recruit polymerase
Eukaryotic_transcription
Enzyme found in humans
activates the proteins. It was named furin because it was in the upstream region of an oncogene known as FES. The gene was known as FUR (FES Upstream
Furin
Stage in cell cycle
protein. ATM/R protein then stabilizes and activates transcription factor p53 so that it can bind to upstream regions of genes, inducing the expression
G1/S_transition
Mammalian protein found in Homo sapiens
is not due to polymerase I itself but to a transcription factor called upstream binding factor, UBF. SLI functions in assembling the transcription preinitiation
Selective_factor_1
Protein domains
RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter". The Journal of Biological Chemistry. 280
TBP-associated_factor
Protein in translation of RNA
Eukaryotic Initiation Factor 2 (eIF2) is a eukaryotic initiation factor. It is required for most forms of eukaryotic translation initiation. eIF2 mediates
EIF2
Protein-coding gene in the species Homo sapiens
TFAM gene. This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription and participates in mitochondrial
TFAM
Obesity caused by a mutation in a single gene
PC1/3. Studies hypothesize that PC1/3 works upstream of Cp3 to regulate its cleavage activity and activate proneurohormones into prominent mature proteins
Monogenic_obesity
Protein-coding gene in the species Homo sapiens
is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific
NFIL3
Directional flow in a water body
currents. In a stream or river the current is influenced by gravity; the term upstream (or upriver) refers to the direction towards the source of the stream (or
Current_(hydrology)
Trans-acting transcriptional activator
cyclic-AMP ligand, CAP binds a DNA region upstream from the site at which RNA polymerase binds and activates transcription through protein-protein interactions
Catabolite_activator_protein
Protein found in humans
(2005). "Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription"
COUP-TFII
Mammalian protein found in humans
probes of biology. mTOR integrates the input from upstream pathways, including insulin, growth factors (such as IGF-1 and IGF-2), and amino acids. mTOR
MTOR
Cellular second messenger
receptor protein), a transcription activator protein. The protein assumes its active shape and binds to a specific site upstream of the lac promoter, making
Cyclic adenosine monophosphate
Cyclic_adenosine_monophosphate
Name of the protein necessary for prokaryotic regulation
prokaryotic regulation transcription factor sigma N (sigma 54) to form an open complex with RNA polymerase in order to activate glnA transcription. The closed
NtrC
Region of non-coding DNA that regulates the transcription of neighboring genes
but not always upstream of the transcription site. CREs contrast with trans-regulatory elements (TREs). TREs code for transcription factors.[citation needed]
Cis-regulatory_element
Protein found in humans
cell-signaling and cell-activating agents: IP3 elevates cytosolic Ca2+ and thereby various Ca2+-sensitive elements while DAG activates various protein kinase
Fibroblast growth factor receptor 1
Fibroblast_growth_factor_receptor_1
Class of enzymes
the movement of the activation loop. There is considerable specificity in the binding of cyclins to CDKs. In addition to activating the CDKs, cyclins can
Cyclin-dependent_kinase
Process by which a gene can code for multiple proteins
donor site complex assists in binding of the splicing factor U2AF to the 3' splice site upstream of the exon, through a mechanism that is not yet known
Alternative_splicing
Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA
Cleavage and polyadenylation specificity factor
Cleavage_and_polyadenylation_specificity_factor
Signaling pathway that controls organ size
tissue growth. Nevertheless, Fat is recognized as an upstream regulator of the Hpo pathway. Fat activates Hpo through the apical protein Expanded (Ex; FRMD6/Willin
Hippo_signaling_pathway
GTP-binding proteins functioning on cell-cycle regulation
form is "off" or "inactive" for signaling, GTPase Activating Protein inactivates Ras by activating its GTPase activity. Thus, GAPs accelerate Ras inactivation
Ras_GTPase
Transcription factor
H3K9ac, H3K14ac, H3K18ac, and H3K23ac). SAGA interacts with DNA via upstream activation sequences (UAS). SALSA, an altered form of SAGA, may be involved
SPT20
Operon
process. An additional site, known as the activating site, is found following the external operator, but upstream of PG2. This site serves as the binding
Gal_operon
Cellular stress response
The activated transcription factor upregulates UPR 'stress genes' by directly binding to stress element promoters in the nucleus. ATF6 (activating transcription
Unfolded_protein_response
Polyfunctional cytokine
(October 1997). "Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative
Leukemia inhibitory factor receptor
Leukemia_inhibitory_factor_receptor
Transcription factor gene of the SOX family
activates SOX-9 activity by binding to an enhancer sequence upstream of the gene. Next, SOX9 activates FGF9 and forms feedforward loops with FGF9 and PGD2. These
SOX9
FGF could activate Xbra expression through Ets2, a FGF target transcription factor that binds to an FGF-responsive element of the upstream sequence (16)
Fibroblast growth factor and mesoderm formation
Fibroblast_growth_factor_and_mesoderm_formation
Protein which binds to a ribosome during translation
Initiation factors can interact with repressors to slow down or prevent translation. They have the ability to interact with activators to help them
Initiation_factor
E. coli gene
Fis has been known to activate ribosomal RNA transcription, as well other genes. It has a direct role in upstream activation of rRNA promoters. Fis binds
Fis
Protein-coding gene in humans
tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB". Mol.
TRAF2
Form of programmed cell death
Weak external signals may also activate the intrinsic pathway of apoptosis. Both pathways induce cell death by activating caspases, which are proteases
Apoptosis
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
formation is often downstream of the stress-activated phosphorylation of eukaryotic translation initiation factor eIF2α; this does not hold true for all types
Stress_granule
Protein-coding gene in the species Homo sapiens
detect the presence of the virus and bind to MAVS, thereby activating MAVS. The activation of MAVS leads the virally infected cell to secrete cytokines
Mitochondrial antiviral-signaling protein
Mitochondrial_antiviral-signaling_protein
RNA element
between two cistrons encoding two different reporter proteins. A promoter upstream of the first cistron drives transcription of both cistrons in a single
Internal_ribosome_entry_site
Non-coding RNA in hepatitis delta virus
P2 is proposed to have an activating role for both genomic and antigenomic ribozyme. Alt2 is an interaction between upstream flanking sequence and the
Hepatitis delta virus ribozyme
Hepatitis_delta_virus_ribozyme
Protein-coding gene in the species Homo sapiens
is an upstream stimulating factor, which is involved in mediating recruitment of chromatin remodelling enzymes and interacting with co-activators and members
C1orf198
Protein-coding gene in the species Homo sapiens
RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product
Transcription factor IIIB 50 kDa subunit
Transcription_factor_IIIB_50_kDa_subunit
Protein-coding gene in the species Homo sapiens
upstream element-binding protein 1 is a protein that in humans is encoded by the FUBP1 gene. This gene encodes a ssDNA binding protein that activates
Far upstream element–binding protein 1
Far_upstream_element–binding_protein_1
Human gene and protein
prostaglandin D synthase gene expression by activator protein-2beta in proximal promoter and upstream stimulatory factor 1 within intron 4 in human brain-derived
TFAP2B
Overreaction of the immune system to an antigen
Chisei; Okayama, Yoshimichi (May 2010). "Activation of human mast cells through the platelet-activating factor receptor". Journal of Allergy and Clinical
Hypersensitivity
Mammalian protein found in Homo sapiens
large number of upstream activators and signals, ranging from epidermal growth factor, heregulin-beta 1, Vascular endothelial growth factor, basic fibroblast
PAK1
Protein found in humans
phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptor". Molecular and Cellular
Colony stimulating factor 1 receptor
Colony_stimulating_factor_1_receptor
Regulatory protein found in most eukaryotic tissues
Ubiquitylation involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes
Ubiquitin
Protein found in humans
member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus
Death_receptor_4
Protein-coding gene in the species Homo sapiens
regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to
MAPK1
Species of bacterium
Type I promoters consists of a consensus -35 and -10 region (Pribnow box) upstream of the gene start site. Heidorn et al. 2011 compiled a list of native Synechocystis
Synechocystis_sp._PCC_6803
Biochemical method
transcription activator protein Gal4, and the UAS (Upstream Activation Sequence), an enhancer to which GAL4 specifically binds to activate gene transcription
GAL4/UAS_system
Protein family
recruit so-called co-activators (such as CBP) that in turn can open up chromatin structure or recruit basal transcription factors. C/EBP proteins interact
CCAAT-enhancer-binding proteins
CCAAT-enhancer-binding_proteins
Protein found in humans
eye and optical nervous system. Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with
COUP-TFI
Protein-coding gene found in Drosophila melanogaster
boundaries of Ubx expression. Activation of Ubx involves multiple cis-acting regulatory sequences, which are found upstream and downstream of the mRNA cap-site
Ultrabithorax
viruses have been reported to target upstream activators of pattern recognition proteins, antagonizing upstream proteins that removed inhibitory post-translational
Viral strategies for immune response evasion
Viral_strategies_for_immune_response_evasion
Chemical compounds
proteins linked to JNK activation. JNKs can associate with scaffold proteins JNK interacting proteins (JIP) as well as their upstream kinases JNKK1 and JNKK2
C-Jun_N-terminal_kinases
Bacterial protein
The CFTR inhibitory factor (Cif) is a protein virulence factor secreted by the Gram-negative bacteria Pseudomonas aeruginosa, Acinetobacter nosocomialis
CFTR_inhibitory_factor
Type of non-coding RNA molecule
transcription factors and form the pre-initiation complex (PIC) prior to the transcription start site at the promoter of genes. In certain cell types, activated enhancers
Enhancer_RNA
UPSTREAM ACTIVATING-FACTOR
UPSTREAM ACTIVATING-FACTOR
Boy/Male
Indian
Living, Captivating, Fascinating
Girl/Female
Arabic, Muslim, Parsi
Captivating; Attractive
Boy/Male
Indian, Punjabi, Sikh
Captivating God
Girl/Female
Muslim
Captivating
Boy/Male
Arabic, Muslim
Fascinating; Captivating
Girl/Female
Arabic, Gujarati, Hindu, Indian, Kannada, Muslim
Captivating
Girl/Female
Muslim
Captivating, Enchanting
Boy/Male
Indian
Captivating, Attractive
Girl/Female
Indian
Captivating, Enchanting
Boy/Male
Muslim
Captivating, Attractive
Girl/Female
Arabic, Muslim
Attractive; Captivating
Girl/Female
Arabic, Australian, French, German
Captivating
Girl/Female
Australian, Hebrew
Captivating
Girl/Female
Tamil
Captivating
Boy/Male
Arabic, German, Indian, Muslim, Turkish
Captivating
Girl/Female
Hebrew
Captivating.
Surname or Lastname
English
English : topographic name for someone who lived beside a stream, Middle English streme.Americanized form of Swedish Ström or Danish Strøm (see Strom).
Boy/Male
Arabic, Muslim, Parsi
Attractive; Captivating
Girl/Female
Arabic, Indian, Muslim, Punjabi, Sikh
Captivating
Boy/Male
Arabic, Indian, Muslim
Captivating
UPSTREAM ACTIVATING-FACTOR
UPSTREAM ACTIVATING-FACTOR
Girl/Female
Assamese, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Telugu
Lustrous
Boy/Male
Tamil
To arrive or to inform, The first life form all knowledgeable and all pure
Girl/Female
Arabic
Assistant; Helper
Boy/Male
Biblical
I alone; his joy; his sharpness of wit; his newness.
Boy/Male
Indian, Tamil
Ancient King
Surname or Lastname
English, French, and Catalan
English, French, and Catalan : from a diminutive of brun ‘brown’ (see Brown, Brun).German : from a personal name (Brunhard) composed with Old High German, Old Saxon brūm ‘brown’. But this is also a Waldensian name in Germany, in which case it is of French origin, see 1.A Brunet from the Charente Maritime region of France is documented in Montreal in 1663, with the secondary surname Belhumeur. Another, from the Perche region, is documented in Quebec city in 1667, with the secondary surname Létang. Other secondary surnames recorded are Bourbonnais, La Sablonnière, and Saint-André. A Calvinist from La Rochelle, with the secondary surname Bonvouloir, is documented in Quebec city in 1698.
Boy/Male
Tamil
Sivanantham | ஸீவாநாநதம
Lord Shiva
Boy/Male
Sikh
Surname or Lastname
English
English : nickname for a man with curly hair, from Middle English crisp, Old English crisp, cryps (Latin crispus), reinforced in Middle English by an Old French word also from Latin crispus.Americanized spelling of the German cognate Krisp, from Middle High German krisp, krispel ‘curly-haired man’.Americanized form of German Krisp, from a short form the medieval personal name Krispin (see Crispin).
Boy/Male
Hindu, Indian, Traditional
Summary
UPSTREAM ACTIVATING-FACTOR
UPSTREAM ACTIVATING-FACTOR
UPSTREAM ACTIVATING-FACTOR
UPSTREAM ACTIVATING-FACTOR
UPSTREAM ACTIVATING-FACTOR
v. i.
To flow.
n.
The art or practice of captivating the hearts of women.
a.
Having power to captivate or charm; fascinating; as, captivating smiles.
n.
A continued current or course; as, a stream of weather.
p. pr. & vb. n.
of Captivate
n.
The act of captivating.
v. i.
To issue or flow in a stream; to flow freely or in a current, as a fluid or whatever is likened to fluids; as, tears streamed from her eyes.
v. t.
To send forth in a current or stream; to cause to flow; to pour; as, his eyes streamed tears.
p. pr. & vb. n.
of Actuate
a.
Having power to bewitch or fascinate; enchanting; captivating; charming.
n.
Current; drift; tendency; series of tending or moving causes; as, the stream of opinions or manners.
n.
A courting of favor or applause, by flattery or address; a captivating quality; an attraction.
n.
A current of water or other fluid; a liquid flowing continuously in a line or course, either on the earth, as a river, brook, etc., or from a vessel, reservoir, or fountain; specifically, any course of running water; as, many streams are blended in the Mississippi; gas and steam came from the earth in streams; a stream of molten lead from a furnace; a stream of lava from a volcano.
v. i.
To issue in a stream of light; to radiate.
a.
Captivating; alluring.
v. i.
To pour out, or emit, a stream or streams.
adv.
Toward the higher part of a stream; against the current.
a.
Literally, that kills; having power to kill; fatal; in a colloquial sense, conquering; captivating; irresistible.
n.
Anything issuing or moving with continued succession of parts; as, a stream of words; a stream of sand.
adv.
Toward the higher part of a street; as, to walk upstreet.