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See searches and references containing THYROGLOBULIN!THYROGLOBULIN
Protein produced and used by the thyroid
Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is
Thyroglobulin
Endocrine gland in the neck
directly the main carriers of the thyroid hormones, thyroglobulin and throxine-binding globulin. Thyroglobulin will also be measurable in a healthy thyroid,
Thyroid
Enzyme expressed mainly in the thyroid gland
iodide ions to form iodine atoms for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), the thyroid
Thyroid_peroxidase
Protein family
Thyroglobulin type-1 repeat is an evolutionary conserved protein domain. Thyroglobulin type 1 repeats are thought to be involved in the control of proteolytic
Thyroglobulin_domain
Species of salamander
tyrosyl residues of thyroglobulin. Two iodinated tyrosyl residues are conjugated together. When they are cleaved from the thyroglobulin chain, thyroid hormone
Axolotl
Antibodies targeted against the thyroid
(anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb). TRAb's are subdivided into activating, blocking and
Antithyroid_autoantibodies
place in the thyroid gland. It is the incorporation of iodine into thyroglobulin for the production of thyroid hormone, a step done after the oxidation
Organification
Hormones produced by the thyroid gland
follicular cells of the thyroid gland. It is produced from the precursor thyroglobulin (this is not the same as thyroxine-binding globulin [TBG]), which is
Thyroid_hormones
Medical condition
interpreting thyroglobulin results without thyroglobulin antibodies, since thyroglobulin antibodies commonly interfere in thyroglobulin immunoassays causing
Thyrotoxicosis_factitia
Autoimmune disease
autoimmunity have been proposed: Via thyroglobulin iodination: Iodine exposure leads to higher iodination of thyroglobulin, increasing its immunogenicity by
Hashimoto's_thyroiditis
Insufficient production of thyroid hormones
autoantibodies against specific thyroid antigens such as thyroid peroxidase, thyroglobulin and the TSH receptor. Autoimmune thyroiditis (Hashimoto's) is associated
Hypothyroidism
Autoimmune endocrine disease
linked to multiple genes Genes believed to be involved include those for thyroglobulin, thyrotropin receptor, protein tyrosine phosphatase nonreceptor type
Graves'_disease
Thyroid hormone
oxidase DUOX2. The oxidized iodine then iodinates tyrosyl residues of thyroglobulin (Tg), a glycoprotein synthesized by thyroid cells and stored in the
Thyroxine
Collective term for blood tests used to check the function of the thyroid
Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. TFTs may be requested if a patient is thought
Thyroid_function_tests
Medical condition
endocrinologist and a surgeon (head and neck surgeon or endocrine surgeon). Thyroglobulin can be used as a tumor marker for well-differentiated papillary thyroid
Papillary_thyroid_cancer
Family of glycoprotein hormones in vertebrata
triiodothyronine (T3) that remain attached to the thyroglobulin protein. (4) Increased endocytosis of the iodinated thyroglobulin protein across the apical membrane
Thyroid-stimulating_hormone
Tumor of the thyroid gland
and very focal expression of thyroglobulin i Lipid-rich follicular thyroid carcinoma (a) immunoreactive for thyroglobulin (b); the ultrastructural study
Thyroid_neoplasm
Medication used for hyperthyroidism
peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine)
Carbimazole
Chemical compound
thyroperoxidase iodinates the tyrosyl residues of the thyroglobulin within the colloid. The thyroglobulin was synthesised in the ER of the follicular cell
Triiodothyronine
Hormone-producing cell in the thyroid gland
acids from the blood circulation on the basolateral side, synthesize thyroglobulin and thyroperoxidase from amino acids and secrete these into the thyroid
Thyroid_follicular_cell
Chemical compound
facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin, a necessary step in the synthesis of triiodothyronine (T3) and thyroxine
Thiamazole
Chemical compound
The drug acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. The clinical effects of the drug to treat the
Methylthiouracil
Effect of iodine on the thyroid
injection of iodine in rats almost completely inhibited organification (thyroglobulin iodination) in the thyroid gland. However, recent[when?] research into
Wolff–Chaikoff_effect
Malignant tumor made of hormone-producing cells in the thyroid gland
thyroid cancer and occurs more commonly in women over 50 years of age. Thyroglobulin (Tg) can be used as a tumor marker for well-differentiated follicular
Follicular_thyroid_cancer
Type of allergic reaction
neuropathies Schwann cell antigen Neuritis, paralysis Hashimoto's thyroiditis Thyroglobulin antigen Hypothyroidism, hard goiter, follicular thymitis Inflammatory
Type_IV_hypersensitivity
Glands of the endocrine system that secrete hormones to blood
consists of follicles with a stored protein called colloid, containing thyroglobulin, a precursor to other thyroid hormones, which are manufactured within
Endocrine_gland
Topics referred to by the same term
Anti-transglutaminase antibodies Anti-topoisomerase antibodies Anti-thyroglobulin antibodies This disambiguation page lists articles associated with the
ATA_antibodies
Medical condition
against different normal components of the thyroid gland, most commonly thyroglobulin, thyroid peroxidase, and the TSH receptor. These antibodies cause the
Thyroid_disease
Medication used to treat hyperthyroidism
facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin. This is one of the essential steps in the formation of thyroxine (T4)
Propylthiouracil
Protein-coding gene in the species Homo sapiens
overall health, in good status. Within the thyroid follicular cell, thyroglobulin is hydrolyzed to form thyroid hormones and mono- and diiodotyrosine
Iodotyrosine_deiodinase
thyroid gland, the antigen was thyroglobulin. He was a mentor to Noel Rose in this research endeavor to prepare thyroglobulin from rabbits. In 1967 the State
Ernst_Witebsky
Proxy markers for certain cancers
tumor thymidine kinase lymphoma, leukemia, lung cancer, prostate cancer thyroglobulin (Tg) post-operative marker of thyroid cancer (but not in medullary thyroid
Tumor_marker
Malignancy originating in the thyroid gland
body scans, and routine laboratory blood tests for changes in thyroglobulin, thyroglobulin antibodies, or calcitonin, depending on the subtype of thyroid
Thyroid_cancer
Medical intervention
eradicated, and there may be a drop in the cancer blood marker test, thyroglobulin, TG, as the node become non-functional. Another interventional use for
Medical_ultrasound
Thyroid hormone medication
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Levothyroxine
Topics referred to by the same term
Garden (fetish club), London, England Thapsigargin, a tumor promoter Thyroglobulin, a protein Transgenic, the transfer of genes between organisms Triglyceride
TG
Protein-coding gene in the species Homo sapiens
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Osteoglycin
Topics referred to by the same term
in certain autoimmune diseases Anti-topoisomerase antibodies Anti-thyroglobulin antibodies Allen Telescope Array Atmosphere absolute, a variant of the
Ata
Medical condition
believed that antibodies binding to the follicular cells, colloid, or thyroglobulin antigens activate the process that causes follicular destruction. Breed
Hypothyroidism_in_dogs
Medical condition
Neonatal jaundice Umbilical hernia Occasional Abnormality of circulating thyroglobulin concentration Slow heart rate Saddle nose deformity Edema of face Decreased
Thyroid_dyshormonogenesis
Medical condition
(ng/dL divided by μg/dL). Nearly all patients have increased serum thyroglobulin, which is consistent with follicular destruction. Thyroid scans using
De_Quervain's_thyroiditis
Isotope of iodine
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Iodine-131
Protein family
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Glycophorin
Chemical-analysis technique
molecular weight), and a sample containing a very large molecule such as thyroglobulin to determine the void volume. (Blue dextran is not recommended for Vo
Size-exclusion_chromatography
Medical condition
Lymphoma Neprilysin Lymphosarcoma CD3 CD79a Endocrine Thyroid cancer Thyroglobulin Medullary thyroid cancer (Calcitonin Carcinoembryonic antigen) Pheochromocytoma
Germinoma
Chemical element with atomic number 34 (Se)
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Selenium
Digestive organ
antigens and associated autoimmune diseases, secretion of glycoproteins (thyroglobulin and mucin) and peptide hormones, the digesting and readsorbing ability
Stomach
Chemical compound
1971 showed that CB interferes with the release of iodine derived from thyroglobulin and blocks colloid endocytosis. Moreover, it was found that CB has an
Cytochalasin_B
Polymer in bacterial cell walls
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Peptidoglycan
Chemical compound
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
VK2809
Scientist at McGill University
important discoveries in glycobiology. She discovered in 1969 that thyroglobulin undergoes carbohydrate modifications, part of a class of proteins known
Annette_Herscovics
Chemical compound containing carbon and at least one halogen
antithyroid agents. In large doses, iodides inhibit proteolysis of thyroglobulin, which permits TH to be synthesized and stored in colloid, but not released
Halocarbon
Chemical compound
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Resmetirom
Mammalian protein found in Homo sapiens
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Protein_C
Amino acid
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Tyrosine
Thyroid hormone deficiency present at birth
thyrotropin (TSH) resistance, iodine trapping defect, organification defect, thyroglobulin, and iodotyrosine deiodinase deficiency. In a small proportion of cases
Congenital_hypothyroidism
Chemical element with atomic number 53 (I)
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Iodine
process with antibody production ( anti-thyroid peroxidase and anti-thyroglobulin antibodies) , which will eventually contribute to the chronicity of
Radiation-induced_thyroiditis
follistatin-like domain (FS), extracellular calcium-binding domain (EC), and thyroglobulin type-1 domain (TY) fold into a compact FS–EC–TY core that enables activity
Testican
Thyroid gland prepared for medical use
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Desiccated_thyroid_extract
Hormone antagonist acting upon thyroid hormones
thyroperoxidase), decreasing iodide oxidation, iodination of tyrosyl residues in thyroglobulin, and coupling of iodotyrosyl and iodothyronyl residues. It is thought
Antithyroid_agent
Excessive production of thyroid hormone
Thyrostatics are believed to work by inhibiting the iodination of thyroglobulin by thyroperoxidase and, thus, the formation of tetraiodothyronine (T4)
Hyperthyroidism
antibodies to red blood cells, platelets, lymphocytes, clotting factors, and thyroglobulin. The disease can result in deposition of immune complexes or autoimmune
List_of_dog_diseases
Human chromosome
staufen double-stranded RNA binding protein 2 SYBU: Syntabulin TG: thyroglobulin THAP1: THAP domain containing, apoptosis associated protein 1 TMEM67:
Chromosome_8
Chemical changes in proteins following their translation from mRNA
an iodine atom to the aromatic ring of a tyrosine residue (e.g. in thyroglobulin) nucleotide addition such as ADP-ribosylation persulfidation, the addition
Post-translational modification
Post-translational_modification
Species of mammal
Korean hare, Lepus coreanus (Mammalia, Lagomorpha), revealed by nuclear thyroglobulin gene and mtDNA control region sequences". Biochemical Genetics. 48 (7–8):
Chinese_hare
Mammalian protein found in Homo sapiens
all functional aspects of the thyroid cell, including iodine pumping; thyroglobulin synthesis, iodination, endocytosis, and proteolysis; thyroid peroxidase
Thyrotropin_receptor
Species of mammal
Korean hare, Lepus coreanus (Mammalia, Lagomorpha), revealed by nuclear thyroglobulin gene and mtDNA control region sequences". Biochemical Genetics. 48 (7–8):
Korean_hare
Ion, and compounds containing the ion
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Perchlorate
Most aggressive form of thyroid cancer
and PAX8 proteins and is negative for thyroid transcription factor-1, thyroglobulin, and calcitonin. ATC cells demonstrate high levels of PD-L1 expression
Anaplastic_thyroid_cancer
Antibody directed against an autogenic protein
(microsomal) Hashimoto's thyroiditis, Graves' disease Anti-thyroglobulin antibodies (TgAbs) Thyroglobulin Hashimoto's thyroiditis Anti-thyrotropin receptor antibodies
Autoantibody
Human protein
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Mucin_short_variant_S1
Medical condition
ocular signs and symptoms, but positive tests for antibodies (anti-thyroglobulin, anti-microsomal and anti-thyrotropin receptor) and abnormalities in
Graves'_ophthalmopathy
Protein with oligosaccharide modifications
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Glycoprotein
Medical condition
immunohistological features of susceptible women are indicated by: antibodies to thyroglobulin (TgAb) antibodies to thyroid peroxidase (TPOAb) increase in TPOAb subclasses
Postpartum_thyroiditis
Psychiatric factitious disorder
thyroid uptake, which would be elevated in true hyperthyroidism Low thyroglobulin levels, which should be elevated in true hyperthyroidism Hypoglycaemia
Factitious disorder imposed on self
Factitious_disorder_imposed_on_self
Organosulfur compound (S=C(NH2)2)
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Thiourea
Organosulfur compounds with an >NC(=S)N< structure
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Thioureas
German nuclear medicine physician and hospital manager
the University of Würzburg in Nuclear Medicine about "Serum thyroglobulin and thyroglobulin antibodies in thyroid carcinoma and other thyroid disorders"
Christoph_Reiners
Class of compounds
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Proteoglycan
Beta blocker drug
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Propranolol
Protein-coding gene in the species Homo sapiens
process regulation of transcription, DNA-templated cellular response to Thyroglobulin triiodothyronine regulation of cellular response to drug transcription
Nuclear receptor coactivator 1
Nuclear_receptor_coactivator_1
Medical condition
subacute granulomatous thyroiditis by lack of pain, presence of TPO or thyroglobulin (Tg) antibodies, and normal inflammatory markers. Fine needle aspiration
Subacute_thyroiditis
Plummer effect, a high iodine concentration inhibits the proteolysis of thyroglobulin and the release of pre-formed thyroid hormones from thyroid follicles
Plummer_effect
Nuclear protein
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Thyroid_hormone_receptor
Protein-coding gene in humans
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
TNFSF9
Chemical compound
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Liothyronine
Mammalian protein found in Homo sapiens
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Haptoglobin
Protein family
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Glypican
Common human medical data ranges for blood test results
triiodothyronine 60, 75 175, 181 ng/dL 0.9, 1.1 2.5, 2.7 nmol/L Thyroxine-binding globulin (TBG) 12 30 mg/L Thyroglobulin (Tg) 1.5 30 pmol/L 1 20 μg/L
Reference ranges for blood tests
Reference_ranges_for_blood_tests
Protein domain
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
ADAM_(protein)
Mammalian protein found in Homo sapiens
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Thrombopoietin
Biochemical classification for carbohydrates
component Sialoglycoprotein CD43 Glycophorin Glycophorin C Thrombopoietin Thyroglobulin Thyroxine-binding proteins Transcortin Tumor necrosis factor alpha Uteroglobin
Glycoconjugate
Chemical compound
Goldberg MA, et al. (January 2014). "Anatabine supplementation decreases thyroglobulin antibodies in patients with chronic lymphocytic autoimmune (Hashimoto's)
Anatabine
Medical condition
the Multinodular Goiter-1 Locus and Exclusion of the Candidate Genes Thyroglobulin, Thyroperoxidase, and Na+/I− Symporter*". The Journal of Clinical Endocrinology
Nontoxic_multinodular_goitre
Canadian cell biology researcher, professor
thyroid gland, presumably incorporated into the thyroid hormone precursor thyroglobulin. To localize this label more precisely within the thyroid tissue, Leblond
Charles_Philippe_Leblond
Neurotoxin
of thyroglobulin type I domain (Thyroglobulin type-1 1 and Thyroglobulin type-1 2) and a signal peptide. Based on the presence of the thyroglobulin domains
U24-ctenitoxin-Pn1a
British scientist
Deborah Doniach and Peter Campbell, he made the classic discovery of thyroglobulin autoantibodies in Hashimoto's thyroiditis which helped to open the whole
Ivan_Roitt
Chemical compound
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Thiocyanate
Chemical compound
sodium (sodium iopodate) Propranolol Propylthiouracil Others Iodine Iodine-131 Selenium Thyroglobulin Tyrosine See also: Receptor/signaling modulators
Potassium_perchlorate
THYROGLOBULIN
THYROGLOBULIN
THYROGLOBULIN
THYROGLOBULIN
Girl/Female
Indian
Jasmine flower
Female
Chinese
quiet not.
Male
Chinese
worthy brightness.
Boy/Male
Indian
Slave of the firm, Servant of the strong (Allah)
Boy/Male
German, Latin
City-dweller; Educated Man
Girl/Female
Indian
Girl/Female
Tamil
Durvisha | தà¯à®°à¯à®µà¯€à®·à®¾Â
Boy/Male
English American Teutonic French
Tailor.
Girl/Female
Muslim
Lucky, Fortunate, Fortune
Boy/Male
Irish
Happy.
THYROGLOBULIN
THYROGLOBULIN
THYROGLOBULIN
THYROGLOBULIN
THYROGLOBULIN