AI & ChatGPT searches , social queriess for SOFOSBUVIR
Search references for SOFOSBUVIR. Phrases containing SOFOSBUVIR
See searches and references containing SOFOSBUVIR!
Search references for SOFOSBUVIR. Phrases containing SOFOSBUVIR
See searches and references containing SOFOSBUVIR!SOFOSBUVIR
Chemical compound
Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is taken by mouth. Common side effects include
Sofosbuvir
Medication used to treat hepatitis C
Ledipasvir/sofosbuvir, sold under the trade name Harvoni among others, is a medication used to treat hepatitis C. It is a fixed-dose combination of ledipasvir
Ledipasvir/sofosbuvir
Pharmaceutical drug
Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults
Sofosbuvir/velpatasvir
Combination drug
Daclatasvir/sofosbuvir (trade names Darvoni, Sovodak) is a two-drug combination for the treatment of hepatitis C. It is given as a single daily pill containing
Sofosbuvir/daclatasvir
Formulary by the World Health Organization
Daclatasvir/sofosbuvir (daclatasvir + sofosbuvir) Glecaprevir/pibrentasvir (glecaprevir + pibrentasvir) Ravidasvir Sofosbuvir Sofosbuvir/velpatasvir (sofosbuvir +
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
Human viral infection
be cured more than 95% of the time with antiviral medications such as sofosbuvir or simeprevir. Peginterferon and ribavirin were earlier generation treatments
Hepatitis_C
Hepatitis C drug
S. approval of a ledipasvir/sofosbuvir fixed-dose combination tablet for genotype 1 hepatitis C. The ledipasvir/sofosbuvir combination is a direct-acting
Ledipasvir
Chemical compound
Velpatasvir is an NS5A inhibitor (by Gilead) which is used together with sofosbuvir in the treatment of hepatitis C infection of all six major genotypes.
Velpatasvir
Pharmaceutical company of Bangladesh
available products include velpatasvir/sofosbuvir, sofosbuvir/daclatasvir, osimertinib, crizotinib, daclatasvir, sofosbuvir, afatinib, axitinib, brigatinib,
Beacon_Pharmaceuticals
Combination drug
Sofosbuvir/velpatasvir/voxilaprevir, sold under the brand name Vosevi, is a fixed-dose combination medication for the treatment of hepatitis C. It contains
Sofosbuvir/velpatasvir/voxilaprevir
Sofosbuvir/velpatasvir/voxilaprevir
Means of delivering drugs to a cell
early 1990s. ProTides form a critical part of antiviral drugs such as sofosbuvir, tenofovir alafenamide, and remdesivir. The first demonstration of the
Protide
American billionaire businessman
developing drugs such as Atripla (for HIV/AIDS) and commercializing Sovaldi (sofosbuvir) for the treatment of the liver virus hepatitis C. Martin is the recipient
John_C._Martin_(businessman)
Chemical compound
hepatitis C (HCV). The other medications used in combination include sofosbuvir, ribavirin, and interferon, vary depending on the virus type and whether
Daclatasvir
Antiviral medication
it is used in combination with other medications, such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a. It can also be used for
Ribavirin
Chemical compound
for hepatitis C genotype 1 and 4. Medications it is used with include sofosbuvir or ribavirin and peginterferon-alfa. Cure rates are in 80s to 90s percent
Simeprevir
Indian multinational pharmaceutical company
Diabetic Dyslipidemia under brand name "Lipaglyn". SoviHep is the first sofosbuvir brand launched in India by Zydus in the year 2015. In 2019, injectable
Zydus_Lifesciences
Drug for the treatment of hepatitis C
nonstructural protein 5A. In China, it is approved for use in combination with sofosbuvir for treating naïve or interferon‐experienced adults chronically monoinfected
Coblopasvir
American physician and infectious diseases researcher
Dieterich, Douglas; Sulkowski, Mark (August 20, 2015). "Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1". New England Journal of Medicine
Annie_Luetkemeyer
American pharmaceutical company
leader in treatment of the hepatitis C virus by giving it control of sofosbuvir (see below). In October 2011, Gilead broke ground on a massive multi-year
Gilead_Sciences
American organic medicinal chemist (born 1950)
the founders of Pharmasset, a company that would later go on to develop sofosbuvir. The name Pharmasset was derived from 'pharmaceutical assets' and the
Raymond_Schinazi
Medication used to treat a viral infection
viral infections include: Harvoni (sofosbuvir and ledipasvir) Epclusa (sofosbuvir and velpatasvir) Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) Zepatier
Antiviral_drug
infliximab adalimumab ledipasvir etanercept infliximab rituximab adalimumab sofosbuvir infliximab rituximab etanercept aripiprazole adalimumab esomeprazole rosuvastatin
List of largest selling pharmaceutical products
List_of_largest_selling_pharmaceutical_products
PMID 17375979. S2CID 30702170. "FDA Approved Drugs | CenterWatch". "Sofosbuvir (Sovaldi) – Treatment – Hepatitis C Online". www.hepatitisc.uw.edu. Archived
List of drugs by year of discovery
List_of_drugs_by_year_of_discovery
Compound that is metabolized into a pharmacologically active drug
dabigatran etexilate (approved in 2010), gabapentin enacarbil (2011), sofosbuvir (2013), tedizolid phosphate (2014), isavuconazonium (2015), aripiprazole
Prodrug
Enzyme that synthesizes RNA from an RNA template
against Hepatitis C and COVID-19 specifically target RdRp. These include Sofosbuvir and Ribavirin against Hepatitis C and remdesivir, an FDA approved drug
RNA-dependent_RNA_polymerase
Pharmaceutical drug classification
J05AP08 Sofosbuvir J05AP09 Dasabuvir J05AP10 Elbasvir J05AP11 Grazoprevir J05AP12 Coblopasvir J05AP13 Ravidasvir J05AP14 Narlaprevir J05AP51 Sofosbuvir and
ATC_code_J05
Chemical compound
treatment of chronic hepatitis C in adult patients (only in combination with sofosbuvir). In the pivotal clinical trial STORM-C-1, the majority of patients were
Ravidasvir
Pharmaceutical company
further developed by Gilead and approved in December 2013 by the FDA as sofosbuvir (Sovaldi) for the treatment of chronic hepatitis C. Among Pharmasset's
Pharmasset
Biological molecules constituting nucleic acids
inhibitors (NRTIs) include Tenofovir disoproxil, Tenofovir alafenamide, and Sofosbuvir. On the other hand, agents such as Mericitabine, Lamivudine, Entecavir
Nucleotide
Class of pharmaceutical drugs
inhibitors, particularly sofosbuvir and the combination of interferon and ribavirin. Comparing interferon containing therapies, sofosbuvir does not cause neutropenia
NS5B_inhibitor
Chemical compound
superiority of newer direct-acting antiviral agents, such as ledipasvir/sofosbuvir. The SPRINT-1 trial was a phase-II trial of boceprevir in difficult-to-treat
Boceprevir
Drug combination for HIV/AIDS prophylaxis and treatment
coadministered with ritonavir May increase tenofovir concentrations. Ledipasvir/sofosbuvir May increase tenofovir concentrations. Consider alternative Hepatitis
Emtricitabine/tenofovir
Inflammation of the liver
including ledipasvir, daclatasvir, and others NS5B inhibitors, including sofosbuvir, dasabuvir, and others These drugs are used in various combinations, sometimes
Hepatitis
Malaysian civil servant and endocrine surgeon
Sciences Inc for the voluntary license of a miracle drug for Hepatitis C, Sofosbuvir. Despite multiple efforts, negotiation broke down and forced Malaysia
Noor_Hisham_Abdullah
Drug discovery
with protease inhibitors such as glecaprevir or NS5B inhibitors (e.g., sofosbuvir), pegylated interferons (e.g. peginterferon alfa-2a), and ribonucleic
Discovery and development of NS5A inhibitors
Discovery_and_development_of_NS5A_inhibitors
HIV-1 protease inhibitor Saquinavir HIV Simeprevir (Olysio) Hepatitis C Sofosbuvir Hepatitis C nucleoside analogue reverse transcriptase inhibitor Stavudine
List_of_antiviral_drugs
application filed by Gilead Sciences for the Hepatitis C medicine sofosbuvir. For context, Sofosbuvir (brand name: Sovaldi) was listed at $1,000 per pill in the
Pharmaceutical industry in India
Pharmaceutical_industry_in_India
Bangladeshi pharmaceutical company
Adalimumab, and vaccines. In 2015, Incepta launched a generic version of sofosbuvir (Hopetavir) in the local Bangladeshi market. In 2016, Incepta signed a
Incepta_Pharmaceuticals
investigating the use of the "government patent use" as a strategy, to make Sofosbuvir, manufactured by Gilead Sciences, a highly effective treatment for Hepatitis
Government_patent_use
Antiarrhythmic medication
about people who began taking the hepatitis C drugs ledipasvir/sofosbuvir or sofosbuvir along with amiodarone, who developed abnormally slow heartbeats
Amiodarone
New Zealand pharmacologist and gastroenterologist
Foster; Nezam Afdhal; Stuart K. Roberts; et al. (17 November 2015). "Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection". The New England Journal
Catherine_Stedman
Formulary
Daclatasvir/sofosbuvir (daclatasvir + sofosbuvir) Glecaprevir/pibrentasvir (glecaprevir + pibrentasvir) Sofosbuvir Sofosbuvir/velpatasvir (sofosbuvir + velpatasvir)
WHO Model List of Essential Medicines for Children
WHO_Model_List_of_Essential_Medicines_for_Children
Protease inhibitor
3/4A protease inhibitor (by Gilead) that is used in combination with sofosbuvir and velpatasvir. The combination has the trade name Vosevi and received
Voxilaprevir
Signaling proteins released by host cells in response to the presence of pathogens
telaprevir, boceprevir or the nucleotide analog polymerase inhibitor sofosbuvir. Biopsies of patients given the treatment show reductions in liver damage
Interferon
virus Hepatitis C Blood testing for antibodies or viral RNA Antivirals (sofosbuvir, simeprevir, others) Under research Hepatitis D Virus Hepatitis D Immunoglobulin
List_of_infectious_diseases
Nonprofit organization
Michael (January 15, 2015). "Gilead Denied Patent for Hepatitis C drug sofosbuvir in India". Fierce Pharma. Retrieved July 29, 2022. Graham, Camilla S.
Initiative for Medicines, Access, and Knowledge
Initiative_for_Medicines,_Access,_and_Knowledge
Hepatitis C virus protein
Velpatasvir, approved on June 28, 2016 in a FDC with sofosbuvir and on July 17, 2017 in a FDC with sofosbuvir and voxilaprevir Pibrentasvir, approved on August
Hepatitis C virus nonstructural protein 5A
Hepatitis_C_virus_nonstructural_protein_5A
Physician and public health policy expert
provide unlimited access to highly active anti-hepatitis C medication (sofosbuvir/velpatasvir) for its HCV-infected Medicaid and incarcerated populations
Rebekah_Gee
Protein-coding gene in the species Homo sapiens
Genotype Is Associated With Virologic Relapse After 8-Week Treatment With Sofosbuvir, Velpatasvir, and Voxilaprevir". Gastroenterology. 153 (6): 1694–1695
Interferon_lambda_4
are not considered as first-line therapies: Sofosbuvir/Velpatasvir The safety and efficacy of sofosbuvir/velpatasvir was evaluated in a clinical trial
Hepatitis C and HIV coinfection
Hepatitis_C_and_HIV_coinfection
Lawyer and patent reform activist
Frontières), to challenge patents by Gilead Sciences on hepatitis C treatment sofosbuvir, a patent application by Novartis from patenting leukemia drug Gleevec
Priti_Krishtel
Non-departmental public body of the Department of Health in the UK
introduction of new oral therapy for hepatitis C has been criticised. Sofosbuvir was approved in 2015. It costs about £30,000 for 12 weeks treatment. NHS
National Institute for Health and Care Excellence
National_Institute_for_Health_and_Care_Excellence
Leader of the successful campaign to eradicate hepatitis C in Egypt
2018, over 4 million Egyptians had received a full three-month course of sofosbuvir-based therapy at a subsidized cost of EGP 1,400, reducing prevalence from
Omar_Hekal
Club organized to pool members' collective buying power
to help individual patients obtain legal access to generic versions of sofosbuvir, daclatasvir, and ledipasvir. At EASL International Liver Congress, Dr
Buyers_club
Chemical compound
diminished rapidly after the introduction in 2014 of sofosbuvir and the combination ledipasvir/sofosbuvir, drugs that cured hepatitis C, and whose market was
Uprifosbuvir
Group of lymphomas
in <50% of cases. More recently, drugs (e.g. simeprevir, daclatasvir, sofosbuvir, and dasabuvir) that directly inhibit the virus's reproduction have cured
Marginal_zone_lymphoma
Species of virus
host-targeted compounds such as cyclophilin inhibitors and silibinin. Sofosbuvir for use against chronic hepatitis C infection was approved by the FDA
Hepatitis_C_virus
Anarchist biohacking group
publicity for the group, pointing out that they don't address the fact that Sofosbuvir is given as part of a combination therapy or how they calculated the figure
Four Thieves Vinegar Collective
Four_Thieves_Vinegar_Collective
Spanish politician (born 1958)
demands of treatment for all with last generation of antiviral drugs (sofosbuvir, ledipasvir, daclatasvir, etc.). While some countries established a moratorium
Rubén_Moreno_Palanques
Medicine award
resistance. 2020 Michael Sofia Arbutus Biopharma For his work developing Sofosbuvir, and thereby revolutionising the treatment of Hepatitis C infection. 2022
Cameron Prize for Therapeutics of the University of Edinburgh
Cameron_Prize_for_Therapeutics_of_the_University_of_Edinburgh
Pharmaceutical drug
when counting all the system regular medications, the biggest cost being sofosbuvir. Brazil's supreme court ruled in April 2018 to break the patent of Soliris
Eculizumab
2015 Innovation Award in the Bioscience category for the development of sofosbuvir, which was named after Sofia for his contributions to the discovery and
Michael_J._Sofia
Egyptian physician (born 1956)
treatment of up to 150,000 Egyptian patients per year, by introducing the sofosbuvir based regimens. The plan was to treat 300.000 patients by the all oral
Gamal_Esmat
Chemical compound
hospitalization risk by 71%. Galidesivir Remdesivir Lufotrelvir Molnupiravir Sofosbuvir Berliba E, Bogus M, Vanhoutte F, Berghmans PJ, Good SS, Moussa A, et al
Bemnifosbuvir
American chemist
Inc., which developed the breakthrough anti-hepatitis C drug, Sovaldi (sofosbuvir) and was subsequently acquired by Gilead Sciences. Liotta obtained his
Dennis_C._Liotta
Non-profit organization
new combination treatment optimised for public health use: ravidasvir + sofosbuvir. A Phase II/III study in Malaysia and Thailand, co-sponsored by the Malaysian
Drugs for Neglected Diseases Initiative
Drugs_for_Neglected_Diseases_Initiative
Connective tissue disease
dermaititis is associated with subacute bacterial endocarditis, ledipasvir/sofosbuvir, allopurinol, Hodgkin’s and non-Hodgkin’s lymphoma, chronic myelomonocytic
Palisaded neutrophilic and granulomatous dermatitis
Palisaded_neutrophilic_and_granulomatous_dermatitis
Bristol-Myers Squibb Hodgkin lymphoma Atezolizumab Genentech urothelial carcinoma Sofosbuvir/velpatasvir Gilead Sciences chronic hepatitis C virus genotypes 1, 2,
List of drugs granted breakthrough therapy designation
List_of_drugs_granted_breakthrough_therapy_designation
Chemical compound
Georgia State University and the Paul Ehrlich Institute. Favipiravir JK-05 Sofosbuvir White LK, Yoon JJ, Lee JK, Sun A, Du Y, Fu H, et al. (July 2007). "Nonnucleoside
ERDRP-0519
Brazilian biologist
from the prestigious Nature group, Muotri's team says that the drug Sofosbuvir, used to treat hepatitis C, can cure Zika infection, as well as preventing
Alysson_Muotri
analyzed finger-prick samples for HCV antibodies, Viremic persons received sofosbuvir (400 mg daily) plus daclatasvir (60 mg daily) with or without ribavirin
Health_in_Egypt
Enzyme attached to an inert material
other pharmaceutical applications for the production of Odanacatib, and Sofosbuvir. Zaushitsyna O, Berillo D, Kirsebom H, Mattiasson B (2013). "Cryostructured
Immobilized_enzyme
Australian physician and environmentalist
Stuart K.; Mollison, Lindsay C.; Sulkowski, Mark (31 December 2015). "Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection". New England Journal
Lindsay_Mollison
Drug repurposing research related to COVID-19
Coronaviruses species possess an intrinsic resistance to ribavirin. Sofosbuvir/daclatasvir is a drug combination developed to treat hepatitis C. In October
COVID-19 drug repurposing research
COVID-19_drug_repurposing_research
American medicinal chemist
Seley-Radtke KL. Bicyclic and Tricyclic "Expanded" Nucleobase Analogues of Sofosbuvir: New Scaffolds for Hepatitis C Therapies. ACS Infect Dis. 2015;1(8):357–66
Katherine_Seley-Radtke
Two drug combination for the treatment of hepatitis C
are market-available. Competing treatments include Gilead's Harvoni (sofosbuvir and ledipasvir) and AbbVie's Viekira Pak (ombitasvir, paritaprevir, and
Elbasvir/grazoprevir
Type or designation of pharmaceuticals
2014 the price of Gilead's specialty drug for hepatitis C, Sovaldi or sofosbuvir, was $84,000 to $168,000 for a course of treatment in the U.S., £35,000
Specialty drugs in the United States
Specialty_drugs_in_the_United_States
for $11.2 billion, in anticipation of release of the hepatitis C drug sofosbuvir. 22: The United States preventive services task force released a guideline
2010s_in_medicine
Viral protein
Radalbuvir, currently in clinical trials. Setrobuvir, development terminated. Sofosbuvir (Sovaldi; Harvoni (combination with ledipasvir)): nucleotide analog, approved
Hepatitis C virus nonstructural protein 5B
Hepatitis_C_virus_nonstructural_protein_5B
Common health care cost
medicines Access to Medicine Index Unitaid Examples of drug controversies: Sofosbuvir § Economics Daclatasvir § Economics Epinephrine autoinjector § Price Insulin
Medication_costs
recipient of Lasker-Debakey Award in Clinical Medical Research (2016); Sofosbuvir (a medication used to treat hepatitis C) is named in his honor Hee-Sup
List of Cornell University alumni (natural sciences)
List_of_Cornell_University_alumni_(natural_sciences)
Chemical compound
PMC 7089605. PMID 32119961. Elfiky AA (March 2020). "Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase
IDX-184
Medical focused tourism in Moldova
undergo treatment including generic treatment including active substances - sofosbuvir, daclatasvir, ledipasvir, velpatasvir. The results of using antiviral
Medical tourism in the Republic of Moldova
Medical_tourism_in_the_Republic_of_Moldova
which offers its highly effective but costly anti-viral drug Sovaldi (Sofosbuvir) for free. 26 April – Construction of a new Cathedral of the Holy Virgin
2015_in_Georgia_(country)
American public health researcher and epidemiologist
(2018-03-11). "No Difference in Effectiveness of 8 vs 12 Weeks of Ledipasvir and Sofosbuvir for Treatment of Hepatitis C in Black Patients". Clin Gastroenterol Hepatol
Julia_L._Marcus
Chemical compound
progressed so far through development as JK-05.[citation needed] ERDRP-0519 Sofosbuvir Jourdan A (2014-10-14). "China military-linked firm eyes quick approval
JK-05
SOFOSBUVIR
SOFOSBUVIR
SOFOSBUVIR
SOFOSBUVIR
Boy/Male
English
Strong as a castle.
Boy/Male
Tamil
Lord Brahma, Eternal, Accompanied by a protector
Boy/Male
Indian, Sanskrit
Sharp Witted; Light; Lamp of Peace
Boy/Male
Hindu
Lord Ayyappa
Female
English
Pet form of English Lynda, LYNDI means "serpent."
Biblical
returned; turned back; a spark
Boy/Male
Hindu
King of the feet
Biblical
revolting from God
Boy/Male
Teutonic
Free.
Biblical
Shamer, prison; bush; lees; thorn
SOFOSBUVIR
SOFOSBUVIR
SOFOSBUVIR
SOFOSBUVIR
SOFOSBUVIR