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A random hexamer or random hexonucleotides are for various PCR applications such as rolling circle amplification to prime the DNA. They are oligonucleotide
Random_hexamer
reasonable quantity for genomic analysis. The reaction starts by annealing random hexamer primers to the template: DNA synthesis is carried out by a high fidelity
Multiple displacement amplification
Multiple_displacement_amplification
Bioengineering process
an appropriate plasmid. Next, the amplification process begins using random hexamer primers and Φ29 DNA polymerase under error prone rolling circle amplification
Protein_engineering
Range of methods designed for assigning cell types
transcribed into cDNA with regular and modified amine-bases and tagged random hexamer RT primers. Amine-bases mediate the cross-linkage of cDNA to its cellular
Spatial_transcriptomics
DNA reverse transcribed from RNA
to begin reverse transcription. An optimized mixture of oligo-dT and random hexamer primers increases the chance of obtaining full-length cDNA while reducing
Complementary_DNA
FISSEQ Schematic: A tagged random hexamer primer is used to prime M-MuLV reverse transcriptase to generate aminoallyl dUTP- modified cDNA fragments in
Fluorescent in situ sequencing
Fluorescent_in_situ_sequencing
DNA analysis method
is subjected to whole-genome multiple displacement amplification via random hexamer priming and Φ29 DNA polymerase, which has a proofreading activity resulting
Illumina_Methylation_Assay
produced during sequencing, priming of reverse transcription caused by random hexamers. Different tools were developed to attempt to solve each of the detected
List of RNA-Seq bioinformatics tools
List_of_RNA-Seq_bioinformatics_tools
Process of determining the nucleic acid sequence
cDNA pool can be sequenced. This reaction is typically primed using random hexamers, or primers that target the mRNA poly(A) tail. cDNA can then be processed
DNA_sequencing
Chemical compound
often abbreviated LiCH2TMS. It crystallizes as the hexagonal prismatic hexamer [LiCH2TMS]6, akin to some polymorphs of methyllithium. Many adducts have
(Trimethylsilyl)methyllithium
Protein(s) forming a major part of an organism's immune system
or mammalian IgM, which occasionally forms hexamers as well, with six units). IgG can also form hexamers, though no J chain is required. IgA tetramers
Antibody
poly-A tail, a signal specifically found on transcribed genes. Using random hexamers priming, reverse transcriptase (RT) convert all mRNA into cDNA and
Digital transcriptome subtraction
Digital_transcriptome_subtraction
Geometric symmetry in living beings
or 8 times around the axis – referred to as tetramerism, pentamerism, hexamerism and octamerism, respectively. Such organisms exhibit no left or right
Symmetry_in_biology
Antiretroviral medication
interface between HIV-1 viral capsid protein (p24) subunits in capsid hexamers, interfering with essential steps of viral replication, including capsid-mediated
Lenacapavir
Modified forms of synthetic insulin
aggregate into hexamers, a configuration that delays absorption and prolongs the onset of action. Before entering the bloodstream, these hexamers must dissociate
Insulin_analogue
Natural phenomenon that hot water freezes faster than cold
refrigeration setup. Crystallization: A relatively higher population of water hexamer states in warm water might be responsible for the faster crystallization
Mpemba_effect
Detailed maps of cities and towns in the United States
Company. In 1916, Sanborn purchased its last major competitor, the E. Hexamer & Sons of Philadelphia, and became a monopoly. Company headquarters moved
Sanborn_maps
Genus of RNA viruses
(February 1998). "Paramyxovirus RNA synthesis and the requirement for hexamer genome length: the rule of six revisited". Journal of Virology. 72 (2):
Henipavirus
sequencing. Multiplexing PCR primers are then ligated to the PCR amplicons with hexamer barcodes identifying which cell each fragment they are derived from. Unlike
Single-cell DNA template strand sequencing
Single-cell_DNA_template_strand_sequencing
Enzyme
needs of the nervous system where it is specifically expressed. GLUD1 is a hexamer. The monomer unit has: N-terminal Glu-BD(Binding domain) that is composed
Glutamate_dehydrogenase_1
German part of the Revolutions of 1848
Central committee of the German Democrats, together with Reichenbach and Hexamer, at the Second Democratic Congress held in Berlin from 26 October through
German revolutions of 1848–1849
German_revolutions_of_1848–1849
DNA sequencing method
December 1992). "DNA Sequencing by Primer Walking with Strings of Contiguous Hexamers". Science. 258 (5089): 1787–1791. Bibcode:1992Sci...258.1787K. doi:10.1126/science
Primer_walking
to hydrolyze ATP, driving the movement of the branch point. RuvB is a hexamer with helicase activity, and also binds the DNA. As ATP is hydrolyzed, RuvB
Branch_migration
Bacterial DNA primase
bind the DnaB hexamer, the C1 subdomains of the HBDs interact with DnaB at its N-terminal domains on the inner surface of the hexamer ring, while the
DnaG
Soluble protein complex in blood plasma and involved in clot formation
AαBβγ trimers, and finally to (AαBβγ)2 hexamers, i.e. two AαBβγ trimers joined by numerous disulfide bonds. The hexamer is transferred to the Golgi where it
Fibrinogen
Evolution of novel genes from non-genic DNA sequence
boundaries, or for protein-coding genes, a coding score based on nucleotide hexamer frequencies, have instead been employed. Because candidate de novo gene
De_novo_gene_birth
Lab technique in cellular biology
analyzed independently. The cDNA for each experiment can be indexed with a hexamer or octamer barcode, so that these experiments can be pooled into a single
RNA-Seq
Examines sequence information from individual cells
et al. (September 2009). "Digital transcriptome profiling using selective hexamer priming for cDNA synthesis". Nature Methods. 6 (9): 647–649. doi:10.1038/nmeth
Single-cell_sequencing
Enzyme from bacteriophage ϕ29
replication mechanism; multiple-strand displacement amplification. Random primers (hexamers) can be used, no need to design specific primers/target specific
Φ29_DNA_polymerase
Protein isolated from soybean
to fold properly into its hexagonal shape (containing six subunits, a hexamer), it must undergo a very limited proteolysis in a manner similar to the
Soy_protein
Species of bacteriophage
needs to enter the prohead through a tiny pore, which is achieved by a hexamer of gp17 interacting with DNA first, which also serves as a motor and nuclease
Escherichia_virus_T4
Ultralong-acting basal insulin analogue
linkage to lysine at the B29 position allows for the formation of multi-hexamers in subcutaneous tissues. This allows for the formation of a subcutaneous
Insulin_degludec
using PCR amplification. This method involves the use of hexamer primers that bind randomly to the template, followed by DNA elongation using phi29 DNA
G&T-seq
Sequence in a genome
archaeal replicative helicase core, Mcm2-7 is loaded as a head-to-head double hexamer onto DNA to license origins. In S-phase, Dbf4-dependent kinase (DDK) and
Origin_of_replication
Aminotransferase enzyme
enzyme is different between organisms. In Escherichia coli, the enzyme is a hexamer containing six identical subunits. Each subunit has a molecular weight
Branched-chain amino acid aminotransferase
Branched-chain_amino_acid_aminotransferase
Class of enzymes
Oral SOD derived from Bacillus amyloliquefaciens has been evaluated in randomized controlled trials. An 8-week placebo-controlled trial in healthy adults
Superoxide_dismutase
RANDOM HEXAMER
RANDOM HEXAMER
Surname or Lastname
English
English : patronymic from Rand 1.
Surname or Lastname
English
English : unexplained; perhaps a variant of Francom.
Male
Hungarian
 Variant spelling of Hungarian András, ANDOR means "man; warrior." Compare with another form of Andor.
Female
English
Variant spelling of English Randy, RANDI means "worthy of admiration."
Male
Scandinavian
 Scandinavian form of Old Norse Randolfr, RANDOLF means "shield-wolf." Compare with another form of Randolf.
Male
English
 Variant spelling of Middle English Randulf, RANDOLF means "shield-wolf." Compare with other forms of Randolf.
Surname or Lastname
English
English : variant of Ransom.
Surname or Lastname
English
English : variant of Rand 1, from the Old French oblique case.
Male
Norwegian
 Norwegian form of Old Norse Arnþórr, ANDOR means "eagle of Thor." Compare with another form of Andor.
Boy/Male
English
Son of Rand.
Surname or Lastname
English
English : variant spelling of Randall.Americanized spelling of Randel.
Boy/Male
English American
Son of Rand.
Male
English
Medieval form of English Randolf, RANDAL means "shield-wolf."
Female
English
Pet form of English Miranda, RANDY means "worthy of admiration."Â Compare with masculine Randy.Â
Female
English
Short form of English Miranda, RANDA means "worthy of admiration."Â
Surname or Lastname
English (chiefly East Anglia)
English (chiefly East Anglia) : patronymic from the Middle English personal name Rand(e) (see Rand 1).
Surname or Lastname
English
English : probably a variant of Crandon, a habitational name from Crandon in Somerset or Crandean in Falmer, Sussex. Compare Grandin.
Male
English
Pet form of English Randall and Randolph, both RANDY means "shield-wolf." Compare with feminine Randy.
Surname or Lastname
English
English : variant of Brandon.
Surname or Lastname
English or Scottish
English or Scottish : unexplained. Possibly, as Black suggests, a reduced form of Langdon.French : from the old Germanic personal name element Lando (see Land), via the oblique case, Landonis.
RANDOM HEXAMER
RANDOM HEXAMER
Girl/Female
Hebrew
He shall add.
Girl/Female
Tamil
Harshashri | ஹரà¯à®·à®¾à®·à¯à®°à¯€Â
Happiness
Boy/Male
Australian, Celtic
Son of Flann
Boy/Male
Indian, Telugu
Power
Girl/Female
Hindu
One who save the world
Surname or Lastname
English and Irish
English and Irish : reduced form of Mannering.
Boy/Male
Arabic, Muslim, Pashtun
Merciful Heart
Male
English
English unisex name derived from the vocabulary word, WISDOM means simply "wisdom." Wisdom is composed of Wis- from the word wise, from proto-Germanic *wisaz "to know" from PIE wittos "to see," and -dom, from Latin domus, from PIE domo "house."
Surname or Lastname
North German and Dutch
North German and Dutch : from a pet form of the personal name Johan (see John).English : from a medieval pet form of the personal name Jehan (see John).English : in some cases, perhaps from Old Norse Anki, a pet form of a personal name with the first element Arn-, shortened from arnar, the genitive singular of ǫrn ‘eagle’.
Boy/Male
Arabic, Muslim, Pashtun
Bunch of Flowers
RANDOM HEXAMER
RANDOM HEXAMER
RANDOM HEXAMER
RANDOM HEXAMER
RANDOM HEXAMER
p. pr. & vb. n.
of Ransom
v. i.
To go or stray at random.
n.
Anything driven at random.
n.
Random.
adv.
In a random manner.
n.
Extra hazard; chance; accident; random.
n.
Distance to which a missile is cast; range; reach; as, the random of a rifle ball.
n.
To redeem from captivity, servitude, punishment, or forfeit, by paying a price; to buy out of servitude or penalty; to rescue; to deliver; as, to ransom prisoners from an enemy.
v. i.
To extend or grow at random.
a.
Going at random or by chance; done or made at hazard, or without settled direction, aim, or purpose; hazarded without previous calculation; left to chance; haphazard; as, a random guess.
n.
The release of a captive, or of captured property, by payment of a consideration; redemption; as, prisoners hopeless of ransom.
n.
To exact a ransom for, or a payment on.
a.
Cruising at random on the ocean.
n.
Ransom; release.
n.
Ransom.
imp. & p. p.
of Ransom
n.
A roving motion; course without definite direction; want of direction, rule, or method; hazard; chance; -- commonly used in the phrase at random, that is, without a settled point of direction; at hazard.
v. i.
To wander at random; to scatter.
adv.
At random; hit or miss. (Obs.)