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Class of proteins allowing diffusion of molecules in or out of a cell
cell. Some permeases, such as the lactose permease LacY, use an existing electrochemical gradient to perform active transport. Other permeases, such as
Permease
Membrane protein
Lactose permease is a membrane protein which is a member of the major facilitator superfamily. Lactose permease can be classified as a symporter, which
Lactose_permease
Family of transport proteins
The sulfate permease (SulP) family (TC# 2.A.53) is a member of the large APC superfamily of secondary carriers. The SulP family is a large and ubiquitous
Sulfate_permease
Protein family
The lactate permease (LctP) family (TC# 2.A.14) is a family of transport proteins belonging to the ion transporter (IT) superfamily. Characterized members
Lactate_permease_family
Phosphate permeases are membrane transport proteins that facilitate the diffusion of phosphate into and out of a cell or organelle. Some of these families
Phosphate_permease
Membrane permease
Amino acid permeases are membrane permeases involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary
Amino_acid_permease
Protein family
The sodium/glutamate symporter, also known as glutamate permease, is a transmembrane protein family found in bacteria and archaea. These proteins are symporters
Glutamate_permease
Membrane protein
Galactoside permease is a protein coded by the lacY gene of the lac operon, and is found bound to the membrane of a cell for the purpose of binding galactoside
Beta-galactoside_permease
Chemical compound
transports and simultaneously phosphorylates its sugar substrates. Mannose XYZ permease is a member of the family, with this distinct method being used by bacteria
Mannose
Set genes encoding proteins and enzymes for lactose metabolism
a disaccharide, into glucose and galactose. lacY encodes β-galactoside permease, a membrane protein which becomes embedded in the Plasma membrane to enable
Lac_operon
Family of transport proteins
Permease of phosphotransferase system (or PTS-AG superfamily according to TCDB) is a superfamily of phosphotransferase enzymes that facilitate the transport
Permease of phosphotransferase system
Permease_of_phosphotransferase_system
Protein family
The potassium (K+) uptake permease (KUP) family (TC# 2.A.72) is a member of the APC superfamily of secondary carriers. Proteins of the KUP/HAK/KT family
Potassium_uptake_permease
Protein family
Kollman J, Park D, Nies DH, Goffeau A, Saier MH (August 1999). "The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human
Resistance-nodulation-cell division superfamily
Resistance-nodulation-cell_division_superfamily
Main transmembrane structural unit of ATP-binding cassette transporter proteins
transporter, permease protein InterPro: IPR011867 Nickel ABC transporter, permease subunit NikB InterPro: IPR014156 Nickel ABC transporter, permease subunit
Transmembrane domain of ABC transporters
Transmembrane_domain_of_ABC_transporters
American biochemist (1936–2019)
the molecular mechanism of membrane transport by focusing on the lactose permease of Escherichia coli (LacY; aka the lactose/H+ symporter), which is now
Howard_Ronald_Kaback
Chemical compound
action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high
Isopropyl β-D-1-thiogalactopyranoside
Isopropyl_β-D-1-thiogalactopyranoside
Chemical compound of RNA
In yeast, uracil concentrations are inversely proportional to uracil permease. Mixtures containing uracil are also commonly used to test reversed-phase
Uracil
Biological process
molecules are transported by transmembrane carrier proteins, such as permeases, that change their conformation as the molecules are carried across (e
Facilitated_diffusion
Protein family
The most recent families added include the PAAP (Putative Amino Acid Permease), LIVCS (Branched Chain Amino Acid:Cation Symporter), NRAMP (Natural
APC_superfamily
Bacterial metabolic pathway
IIA (IIA), and Enzyme IIB (IIB)) as well as the integral membrane sugar permease (IIC).The PTS Enzyme II complexes are derived from independently evolving
PEP_group_translocation
The putative amino acid permease (PAAP) family (TC# 2.A.120) belongs to the APC superfamily. The PAAP family consists of many proteins, all of a uniform
Putative amino acid permease family
Putative_amino_acid_permease_family
Membrane protein involved in transportation
transport are broadly categorized as either channels or carriers (a.k.a. permeases or transporters). Examples of channel/carrier proteins include the GLUT
Membrane_transport_protein
The Pho1 phosphate permease family (TC# 2.A.94) is a family of phosphate transporters belonging to the ion transporter (IT) superfamily. Representative
Pho1_family
Chemical element with atomic number 74 (W)
WtpA is tungsten-binding protein of ABC family of transporters WtpB is a permease WtpC is ATPase Mod and Tup systems, which belong to the ABC family, have
Tungsten
The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family (TC# 2.A.42) is a member of the large Amino Acid-Polyamine-OrganoCation (APC) Superfamily of secondary
HAAAP_family
Class of transport proteins
The Amino Acid/Auxin Permease (AAAP) Family (TC# 2.A.18) is a family of secondary carrier proteins, a member of the APC Superfamily that includes hundreds
AAAP_family
Protein-coding gene in the species Homo sapiens
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent
Proton-coupled amino acid transporter 1
Proton-coupled_amino_acid_transporter_1
this article) and the second mechanism makes use of transition-metal permeases (such as HoxN of Ralstonia eutropha). The ABC-type transporter system
Nik_operon
Enzyme
and is part of the PTS-AG superfamily. A single PTS permease of the L-Asc family of PTS permeases has been functionally characterized. This is the SgaTBA
PTS_L-Ascorbate_Family
Order of gram-negative bacteria
signature indels (CSIs) for this order in the proteins peptide ABC transporter permease, elongation factor P-like protein YeiP, L-arabinose isomerase, pyrophosphatase
Enterobacterales
Family of transport proteins
Xanthine permeases, including PbuX (XanP) of Bacillus subtilis (TC# 2.A.40.3.1), involved in cellular xanthine transport. Uric acid permeases, including
Nucleobase_cation_symporter-2
Species of bacterium
circular megaplasmid for substrate utilization enzymes like raffinose permease. Collins, Matthew D.; Facklam, Richard R.; Farrow, John A.E.; Williamson
Enterococcus_raffinosus
Topics referred to by the same term
names of various Croatian Cups Irv Kupcinet's nickname Potassium Uptake Permease (KUP) family, family of integral membrane transport proteins Kupp, surname
Kup
Protein-coding gene in humans
Nitrogen permease regulator-like 3 is a protein that in humans is encoded by the NPRL3 gene. NPRL3 is a human protein of poorly understood function but
NPRL3
Protein family
together. Three other S. cerevisiae proteins, one of which is the thiamin permease, Thi10 (TC# 2.A.39.4.1), and another of which is the nicotinamide riboside
Nucleobase_cation_symporter-1
Classification of membrane proteins including ion channels
2.A.1 Major Facilitator superfamily (MFS), see also Lactose permease, Phosphate permease and Glucose transporter 2.A.2 The Glycoside-Pentoside-Hexuronide
Transporter Classification Database
Transporter_Classification_Database
Species of bacterium
for growth. External lactate is transported in to the cell via lactate permease (LctP). The N. gonorrhoeae genome encodes for three lactate dehydrogenase
Neisseria_gonorrhoeae
Membrane transport proteins
Acid-Polyamine-Organocation (APC) Superfamily TC# 2.A.18 - Amino Acid/Auxin Permease (AAAP) Family TC# 2.A.23 - Dicarboxylate/Amino Acid:Cation (Na+ or H+)
Amino_acid_transporter
Protein superfamily
(4) nicotinamide ribonucleoside uptake permeases (PnuCs; TC# 4.B.1), (5) 4-toluene sulfonate uptake permeases (TSUPs; TC# 2.A.102), (6) Ni2+–Co2+ transporters;
TOG_superfamily
Mammalian protein found in humans
Ahmed A (March 2006). "Carbon catabolite repression regulates amino acid permeases in Saccharomyces cerevisiae via the TOR signaling pathway". The Journal
MTOR
for a succinate semialdehyde dehydrogenase, GABA transaminase and a GABA permease respectively. There is a regulatory gene csiR, downstream of the operon
Gab_operon
Process of cells digesting parts of themselves
their building blocks are released from the vesicle through the action of permeases. Sirtuin 1 (SIRT1) stimulates autophagy by preventing acetylation of proteins
Autophagy
Type of membrane protein that is permanently attached to the biological membrane
Some types of receptor proteins Glycophorin Rhodopsin Band 3 CD36 Glucose Permease Ion channels and Gates Gap junction Proteins G protein coupled receptors
Integral_membrane_protein
Topics referred to by the same term
refer to: Amateur Astronomers Association of Pittsburgh Amino Acid/Auxin Permease (AAAP) Family, family of secondary transport proteins American Academy
AAAP
DNA screening technique
protein EIIAGlc, which is involved in glucose import, shuts down lactose permease when glucose is being transported into the cell. The media used in agar
Blue–white_screen
Species of bacterium
Wang, T.-Y. (2007). "Identification of a Vibrio furnissii Oligopeptide Permease and Characterization of Its In Vitro Hemolytic Activity". Journal of Bacteriology
Vibrio_furnissii
Family of bacteria
identified in the following proteins: DNA topoisomerase I, ABC transporter permease, citrate synthase, phosphoribosylformylglycinamidine synthase, pyruvate
Thermaceae
Biological membrane that separates the interior of a cell from its outside environment
by transmembrane transporters. Protein channel proteins, also called permeases, are usually quite specific, and they only recognize and transport a limited
Cell_membrane
Viral protein in bacteriophages
protein is transported to neighboring bacteria using the oligopeptide permease (OPP) transporter channel. The OPP transport channel is capable of transporting
Arbitrium
Pathogenic genus of Gram-negative bacteria
serine endoprotease DegP precursor, DNA polymerase I, and ABC transporter permease, that are specifically present in different species of the Legionella.
Legionella
Wine making process
encoding malolactic enzyme from Oenococcus oeni and a gene encoding malate permease from Schizosaccharomyces pombe. S. cerevisiae strain ML01 has received
Fermentation_in_winemaking
Gram-positive bacteria. The sulfate permease, CysP (TC# 2.A.20.4.1), is distantly related to the phosphate permeases. Members of the PiT family arose by
Inorganic phosphate transporter family
Inorganic_phosphate_transporter_family
Bacteriophage that infects Escherichia coli
injected through the outer membrane. The DNA passes through the mannose permease complex in the inner membrane (encoded by the manXYZ genes) and immediately
Lambda_phage
Group of chemical compounds
bacterium E. coli, phosphatidylethanolamine play a role in supporting lactose permeases active transport of lactose into the cell, and may play a role in other
Phosphatidylethanolamine
Species of fungus
(Fe+3) to the ferrous (Fe+2) state and subsequent uptake via FtrA, an iron permease. Targeted mutation of the ftrA gene did not induce a decrease in virulence
Aspergillus_fumigatus
Metabolic process in microorganisms
unphosphorylated form. This leads to inhibition of adenylyl cyclase and lactose permease, therefore cAMP levels are low and lactose can not be transported inside
Catabolite_repression
Species of bacterium
the cell it originated from via a transmembrane protein, oligopeptide permease. In the cytosol the pheromones have two functions in the Rgg2/3 pathway
Streptococcus_pyogenes
Hxt1 and Hxt3. Additionally, the endocytosis of the general amino acid permease Gap1 triggered by stress conditions, occurs without altering the ubiquitination
Alpha_Arrestin
Protein family
(Hg²⁺) Permease (MerH) Family 1.A.72.3: The MerTP Mercuric Ion (Hg²⁺) Permease (MerTP) Family 1.A.72.4: The MerC Mercuric Ion (Hg²⁺) Permease (MerC) Family
Mercury_transporter
Protein domain
acid. Cyanase requires the product of the reaction catalyzed by cyanate permease. Activity of cyanase is also dependent on the concentration of its substrates
Cyanase
Control of DNA to RNA conversion in cells
uniprot.org. Retrieved 20 November 2017. "malF - Maltose transport system permease protein MalF - Escherichia coli (strain K12) - malF gene & protein". www
Transcriptional_regulation
Logic programming using abductive reasoning
rule) that E. coli can feed on the sugar lactose if it makes two enzymes permease and galactosidase. Like all enzymes, these are made if they are coded by
Abductive_logic_programming
Multi-protein system
(HPr). Phospho-HPr then transfers the phosphoryl group to a sugar-specific permease which consists of at least three structurally distinct domains (IIA, IIB
Saccharide_transporter
Protein-coding gene in the species Homo sapiens
G, Bassi MT, Sperandeo MP, et al. (1999). "SLC7A7, encoding a putative permease-related protein, is mutated in patients with lysinuric protein intolerance"
Y+L_amino_acid_transporter_1
Proteins
The 4-Toluene Sulfonate Uptake Permease (TSUP) family (TC# 2.A.102) is also referred to as the TauE/SafE/YfcA/DUF81 Family. Although its members have not
TSUP_family
Protein family
Kaster W, Dassa E (June 1994). "Bacterial binding protein-dependent permeases: characterization of distinctive signatures for functionally related integral
Bacterial binding protein-dependent transporter
Bacterial_binding_protein-dependent_transporter
Family of transport proteins
IIA (IIA), and Enzyme IIB (IIB) as well as the integral membrane sugar permease complex (IICD). It is not part of the PTS-AG or PTS-GFL superfamilies.
PTS Mannose-Fructose-Sorbose Family
PTS_Mannose-Fructose-Sorbose_Family
Family of glycoside hydrolase enzymes
with the lacZ gene deleted (but still containing the gene for galactoside permease, lacY), were plated on medium containing lactose (or other 3-galactosides)
Β-Galactosidase
Protein family
required for nutritional repression of the Bacillus subtilis dipeptide permease operon". Mol. Microbiol. 15 (4): 689–702. doi:10.1111/j.1365-2958.1995
CodY_protein_family
Protein family
(ammonia transporters) in bacteria and plants, methylammonium/ammonium permeases (MEPs) in yeast, or Rhesus (Rh) proteins in chordates. In humans, the
Ammonia_transporter
RNA family
RNA gene overlaps with VCA0943 - a gene coding for a maltose transporter permease - but the ribonuclease RNAase E processes the MicX transcript to create
MicX_sRNA
Gene family
rate-limiting steps. Recently, direct measurement of vinblastine binding to permease-glycoprotein (P-glycoprotein) in the presence of nonhydrolyzable ATP analogs
ABC_transporter
Protein family
(IT) superfamily. Members of the GntP family include known gluconate permeases of E. coli and Bacillus species such as the D-Gluconate:H+ symporter of
Gluconate-proton_symporter
Species of archaeon
racemase and alanine permease for alanine uptake. A racemase enzyme is used to convert the stereochemistry within the molecule. Permease is a protein that
Methanococcus_maripaludis
Belgian molecular biologist
his group subsequently published evidence that the general amino acid permease Gap1 acts as an amino-acid sensor independently of its transport function
Johan_Thevelein
(NC_008254) αr14 gene Avi_5890 D 899428 900909 YP_002547646.1 sulfate permease Agrobacterium vitis S4 chromosome 2 (NC_011988) αr14 sRNA Avr14CII2 D 901035
Αr14_RNA
Protein spanning across a biological membrane
Major Facilitator Superfamily (Glycerol-3-phosphate transporter, Lactose permease, and Multidrug transporter EmrD) Resistance-nodulation-cell division (multidrug
Transmembrane_protein
Genus of bacteria
CoA-transferase subunit B, LTA synthase family protein, sulphate ABC transporter permease subunit CysW, class I SAM-dependent RNA methyltransferase, site-specific
Gottfriedia
RNA family
function of the RNA. However, the genes are sometimes predicted to have a permease activity. Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A
COG3610-DE_RNA_motif
Chemical compound
sets, sets of differential equations follow the time course of lactose permease, internal lactose, β-galactosidase, allolactose, and lac mRNA. In such
Allolactose
Npi-phosphotransferase. Other names in common use include glucose permease, PTS permease, phosphotransferase, phosphohistidinoprotein-hexose, enzyme IIl4ac
Protein-Npi-phosphohistidine-sugar phosphotransferase
Protein-Npi-phosphohistidine-sugar_phosphotransferase
1970 book by Jacques Monod
(consisting of three proteins) in Escherichia coli. He explains that galactoside permease (one of the proteins in the lactose system) enables the galactoside sugars
Chance_and_Necessity
Protein found in humans
1994). "Similarities between a soybean nodulin, Neurospora crassa sulphate permease II and a putative human tumour suppressor". Trends in Biochemical Sciences
Chloride_anion_exchanger
Genus of bacteria
family membrane integrase SpoIIIJ, peptide deformylase and NCS2 family permease. These CSIs provide a novel and reliable means to distinguish Lederbergia
Lederbergia
Class of enzymes
The ABC-type oligopeptide transporter (EC 7.4.2.6) or oligopeptide permease is an enzyme that catalyzes the chemical reaction ATP + H2O + oligopeptide(out)
ABC-type oligopeptide transporter
ABC-type_oligopeptide_transporter
Large group of transport proteins
IIA (IIA), and Enzyme IIB (IIB)) as well as the integral membrane sugar permease (IIC). The PTS Enzyme II complexes are derived from independently evolving
PTS-GFL_superfamily
Chemical compound
glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance". Molecular Microbiology. 100 (6): 945–53
1-Arseno-3-phosphoglycerate
Protein found in humans
mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. Rh family proteins are all predicted
RHBG
Family of transport proteins
O; Eitinger, T (July 2002). "Substrate specificity of nickel/cobalt permeases: insights from mutants altered in transmembrane domains I and II". J.
NiCoT_family
Protein family
2.A.13 - The C4-Dicarboxylate Uptake (Dcu) Family 2.A.14 - The Lactate Permease (LctP) Family 2.A.34 - The NhaB Na+:H+ Antiporter (NhaB) Family 2.A.35
Ion_transporter_superfamily
Class of enzymes
(manganese-importing). This enzyme is also known as ABC-type manganese permease complex. Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic
Manganese-transporting_ATPase
Mateos, LM; Rosen, BP (24 July 2009). "Properties of arsenite efflux permeases (Acr3) from Alkaliphilus metalliredigens and Corynebacterium glutamicum"
ARC3_family
Rgg/SHP quorum sensing system
then internalized by bacterial cells through a conserved oligopeptidase permease family. The internalized, active SHP then associates with Rgg to form a
Regulator gene glucosyltransferases (Rgg/SHP) systems
Regulator_gene_glucosyltransferases_(Rgg/SHP)_systems
Type of cellular growth
exclusion. In this model, glucose transport via the EIIAGlc shuts down lactose permease when glucose is being transported into the cell, so lactose is not transported
Diauxic_growth
Protein family
major facilitator superfamily, most closely related to drug resistance permeases. Proteins of the FBT family are reported to contain about 480 to 650 amino
Folate-biopterin transporter family
Folate-biopterin_transporter_family
Family of transport proteins
interact dynamically with the transporter. The KTN conformation then controls permease activity. Both yeast transport systems are believed to function by K+:H+
Potassium_transporter_family
Protein family
PPases probably use binding of pyrophosphate to drive pumping. Phosphate permease Pyrophosphatase Baltscheffsky M, Schultz A, Baltscheffsky H (September
H+, Na+-translocating pyrophosphatase family
H+,_Na+-translocating_pyrophosphatase_family
Ion channel that selectively passes K+
transporter (Trk) family – Family of transport proteins Potassium uptake permease Sodium ion channel – Transmembrane protein allowing sodium ions in and
Potassium_channel
Medical condition
members of the resistance-nodulation-division (RND) family of prokaryotic permeases, suggesting a pumping function for NPC1. Recent 2008 evidence indicates
Niemann–Pick_disease_type_C
Protein family
members of the POT family catalyze peptide transport, one is a nitrate permease and one can transport histidine, as well as peptides. Some of the peptide
Proton-dependent oligopeptide transporter
Proton-dependent_oligopeptide_transporter
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