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Class of molecules found in the outer membrane of Gram-negative bacteria
Lipopolysaccharide (LPS), now more commonly known as endotoxin, is a collective term for components of the outermost membrane of the cell envelope of Gram-negative
Lipopolysaccharide
Family of kinases
molecular biology, the lipopolysaccharide kinase (Kdo/WaaP) family is a family of lipopolysaccharide kinases that includes lipopolysaccharide core heptose(I)
Lipopolysaccharide kinase (Kdo/WaaP) family
Lipopolysaccharide_kinase_(Kdo/WaaP)_family
Protein in humans
Lipopolysaccharide binding protein (LBP) is a protein that in humans is encoded by the LBP gene. LBP is a soluble acute-phase protein that binds to bacterial
Lipopolysaccharide binding protein
Lipopolysaccharide_binding_protein
Class of enzymes
In enzymology, a lipopolysaccharide N-acetylglucosaminyltransferase (EC 2.4.1.56) is an enzyme that catalyzes the chemical reaction UDP-N-acetyl-D-glucosamine
Lipopolysaccharide N-acetylglucosaminyltransferase
Lipopolysaccharide_N-acetylglucosaminyltransferase
Class of enzymes
enzymology, a lipopolysaccharide glucosyltransferase I (EC 2.4.1.58) is an enzyme that catalyzes the chemical reaction UDP-glucose + lipopolysaccharide ⇌ {\displaystyle
Lipopolysaccharide glucosyltransferase I
Lipopolysaccharide_glucosyltransferase_I
Class of enzymes
In enzymology, a lipopolysaccharide N-acetylmannosaminouronosyltransferase (EC 2.4.1.180) is an enzyme that catalyzes the chemical reaction
Lipopolysaccharide N-acetylmannosaminouronosyltransferase
Lipopolysaccharide_N-acetylmannosaminouronosyltransferase
Class of enzymes
enzymology, a lipopolysaccharide glucosyltransferase II (EC 2.4.1.73) is an enzyme that catalyzes the chemical reaction UDP-glucose + lipopolysaccharide ⇌ {\displaystyle
Lipopolysaccharide glucosyltransferase II
Lipopolysaccharide_glucosyltransferase_II
Class of enzymes
In enzymology, a lipopolysaccharide-transporting ATPase (EC 3.6.3.39) is an enzyme that catalyzes the chemical reaction ATP + H2O + lipopolysaccharidein
Lipopolysaccharide-transporting ATPase
Lipopolysaccharide-transporting_ATPase
Plasma membrane found in gram-negative bacteria
outer membrane of many gram-negative bacteria includes a complex lipopolysaccharide whose lipid portion acts as an endotoxin - and in some bacteria such
Bacterial_outer_membrane
Investigational antibiotic
carbapenem-resistant Acinetobacter baumannii (CRAB). It targets a lipopolysaccharide transporter. It works by recognizing a composite binding site made
Zosurabalpin
Mammalian protein found in humans
immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). It is highly
CD14
Class of enzymes
lipopolysaccharide 3-alpha-galactosyltransferase (EC 2.4.1.44) is an enzyme that catalyzes the chemical reaction UDP-galactose + lipopolysaccharide ⇌
Lipopolysaccharide 3-alpha-galactosyltransferase
Lipopolysaccharide_3-alpha-galactosyltransferase
Protein-coding gene in the species Homo sapiens
chains from the hexaacyl lipid A moiety found in many bacterial lipopolysaccharides (LPSs, also called endotoxins). The resulting tetraacyl LPS is non-stimulatory
AOAH
Protein-coding gene in the species Homo sapiens
LY96 gene. The protein encoded by this gene is involved in binding lipopolysaccharide with Toll-Like Receptor (TLR4). The MD-2 protein appears to associate
Lymphocyte_antigen_96
Species of bacterium
pathogens in plants. A Japanese research group was able to isolate the lipopolysaccharide IP-PA1 in Pantoea agglomerans and found that its low molecular mass
Pantoea_agglomerans
Pharmaceutical compound
support that pinoline has antioxidant properties.[citation needed] Lipopolysaccharide is produced by Gram-negative bacteria and stimulates the production
Pinoline
Aspect of psychology
produced by activated leukocytes in the immune system in response to lipopolysaccharides (a cell wall component of Gram-negative bacteria). These cytokines
Sickness_behavior
Group of bacteria that do not retain the Gram stain used in bacterial differentiation
Furthermore, the outer leaflet of this membrane contains a complex lipopolysaccharide (LPS) whose lipid A component can trigger a toxic reaction when the
Gram-negative_bacteria
disaccharide, heteropolysaccharide, homopolysaccharide, lipooligosaccharide, lipopolysaccharide, monosaccharide, oligosaccharide, pentasaccharide, polysaccharide
List of Greek and Latin roots in English/P–Z
List_of_Greek_and_Latin_roots_in_English/P–Z
Chemical compound
bacteria it is a component of the core oligosaccharide portion of lipopolysaccharides, also known as endotoxin. The d-manno prefix indicates that the four
3-Deoxy-D-manno-oct-2-ulosonic acid
3-Deoxy-D-manno-oct-2-ulosonic_acid
Short chain of sugar residues within Gram-negative lipopolysaccharide
Core-OS) is a short chain of sugar residues within Gram-negative lipopolysaccharide (LPS). Core-OS are highly diverse among bacterial species and even
Core_oligosaccharide
Chemical compound
also serves as the lipid transporter for the O-antigen component of lipopolysaccharide. It is supposed that sugars are assembled into O-antigen subunits
Undecaprenyl_phosphate
Life-threatening response to infection
largely due to a response by the host to the lipid A component of lipopolysaccharide, also called endotoxin. Sepsis caused by gram-positive bacteria may
Sepsis
Protein found in humans
Palsson-McDermott EM, O'Neill LA (October 2004). "Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4". Immunology. 113 (2): 153–162. doi:10
TICAM1
Toxin produced by microorganisms
disabling the immune system. Endotoxins most commonly refer to the lipopolysaccharide (LPS) or lipooligosaccharide (LOS) that are in the outer plasma membrane
Microbial_toxin
Genus of bacteria
some may exhibit an irregular border. The immunochemistry of Hafnia lipopolysaccharides (LPS) are extremely complicated. All H. alvei LPS appear to contain
Hafnia_(bacterium)
filament (rod, hook, and flagellum) passes. The L in L-ring stands for lipopolysaccharide. Jones CJ, Homma M, Macnab RM (July 1989). "L-, P-, and M-ring proteins
L_ring
Laboratory technique in bacterial cell biology
chloride to a cell suspension promotes the binding of plasmid DNA to lipopolysaccharides (LPS). Positively charged calcium ions attract both the negatively
Calcium chloride transformation
Calcium_chloride_transformation
American biochemist and molecular biologist (1927–2019)
and microbiologist known for her research on the biosynthesis of lipopolysaccharide (bacterial endotoxin), a key component of the outer membrane of Gram-negative
Mary_Jane_Osborn
Cell surface receptor found in humans
receptor signaling and degradation. The main ligands for TLR4 are lipopolysaccharides (LPS), the major components of the outer membrane of Gram-negative
Toll-like_receptor_4
Protein-coding gene in humans
in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. Recently
CD180
Chemical used for the detection and quantification of bacterial endotoxins
Limulus polyphemus. LAL reacts with bacterial endotoxins such as lipopolysaccharides (LPS), which are components of the bacterial capsule, the outermost
Limulus_amebocyte_lysate
Protein-coding gene in the species Homo sapiens
Lipopolysaccharide-induced tumor necrosis factor-alpha factor is a protein that in humans is encoded by the LITAF gene. It is associated with Charcot–Marie–Tooth
LITAF
Networks of fibres which bind pathogens
pharmacological agent phorbol myristate acetate (PMA), Interleukin 8 (IL-8) or lipopolysaccharide (LPS), neutrophils release granule proteins and chromatin to form
Neutrophil extracellular traps
Neutrophil_extracellular_traps
Class of enzymes
reaction 3-deoxyoctulosonyl-lipopolysaccharide + H2O ⇌ {\displaystyle \rightleftharpoons } 3-deoxyoctulosonic acid + lipopolysaccharide Thus, the two substrates
3-deoxyoctulosonase
Antimicrobial enzyme produced by animals
competitive inhibition of lysozyme. In Gram-negative bacteria, the lipopolysaccharide acts as a non-competitive inhibitor by highly favored binding with
Lysozyme
Agglutination test for the diagnosis of rickettsial infections
Weil–Felix antibody was recently found to target the rickettsial lipopolysaccharide O-antigen. The basis of the test is the presence of antigenic cross-reactivity
Weil–Felix_test
Genus of bacteria
Leptospira, like those of most other Gram-negative bacteria, contains lipopolysaccharide (LPS). Differences in the highly immunogenic LPS structure account
Leptospira
Topics referred to by the same term
scrimmage, in American football Lipooligosaccharide, a bacterial lipopolysaccharide with a low-molecular-weight LOS AS, a Norwegian electricity supplier
Los
Species of plant
"Anti-inflammatory activity of Cymbopogon citratus leaf infusion in lipopolysaccharide-stimulated dendritic cells: contribution of the polyphenols". Journal
Cymbopogon_citratus
Type of molecules produced by a pathogen that might cause potential harmful effects
into two groups: endotoxins and exotoxins. Endotoxin is a component (lipopolysaccharide (LPS)) of the cell wall of gram-negative bacteria. It is the lipid
Virulence_factor
Species of bacterium
Unlike most Gram-negative bacteria with 6 fatty acyl tails, the lipopolysaccharide (LPS) of F. tularensis contains only 4 atypically long acyl chains
Francisella_tularensis
Chemical compound
and/or daidzein is possible. An in vitro anti-inflammatory effect on lipopolysaccharide (LPS)-induced inflammation has been demonstrated in one study. You-Ping
Ononin
Species of flowering plant in the buttercup family
(2024). "Anti-Inflammatory Effects of Clematis terniflora Leaf on Lipopolysaccharide-Induced Acute Lung Injury". Evidence-Based Complementary and Alternative
Clematis_terniflora
Human gene and protein
Anemia15, Mandibulofacial with Dysostosis, and Keratomalacia. Enables lipopolysaccharide binding, protein binding, heparin binding and CCR2 chemokine receptor
PRR23A
Investigative procedure in microbiology
lipids of the cell membrane. A gram-negative cell loses its outer lipopolysaccharide membrane, and the inner peptidoglycan layer is left exposed. The CV–I
Gram_stain
Species of bacterium
themselves as rough variants, a reflection of their naturally rough lipopolysaccharide (LPS) phenotype. The optimal growth temperature for B. canis is 37°C
Brucella_canis
Genus of bacteria
adhesion, biofilm formation, and protein export as well as motility. The lipopolysaccharide capsule of Enterobacter spp. helps members of this genus avoid phagocytosis
Enterobacter
Species of bacterium
on the capsule and one of 16 Heddleston serovars (1–16) based on lipopolysaccharide (LPS). To classify a strain serologically, the capsule and the LPS
Pasteurella_multocida
Index of articles associated with the same name
protein 4 EP300 Binding immunoglobulin protein Odorant binding protein Lipopolysaccharide-binding protein C4b-binding protein Rap GTP-binding protein Calmodulin-binding
Binding_protein
Domain of microorganisms
of peptidoglycan surrounded by a second lipid membrane containing lipopolysaccharides and lipoproteins. Most bacteria have the Gram-negative cell wall
Bacteria
Enzyme found in humans
to vitamin A arginine catabolic process to ornithine response to lipopolysaccharide response to manganese ion response to wounding response to axon injury
Arginase-1
Class of chemical compounds
Superantigen type II Pore-forming toxin type III AB toxin/AB5 Endotoxin Lipopolysaccharide Lipid A Bacillus thuringiensis delta endotoxin Cry1Ac Cry3Bb1 Other
Bufotoxin
Genus of bacteria
contain glycosphingolipids (GSLs), specifically ceramide, instead of lipopolysaccharide (LPS) in their cell envelopes, and typically produce yellow-pigmented
Sphingomonas
Class of immune system proteins
characterized and identified as a lipopolysaccharide (LPS) produced by most Gram-negative bacteria. This lipopolysaccharide is an integral part of the gram-negative
Toll-like_receptor
Species of bacterium
identified to be a rough type lipopolysaccharide with a molecular weight of 5300 KD, and the purified lipopolysaccharide was toxic to the slug with an
Moraxella_osloensis
Protein family
family include: Bactericidal permeability-increasing protein (BPI) Lipopolysaccharide-binding protein (LBP) Cholesteryl ester transfer protein (CETP) Phospholipid
Lipid-binding serum glycoprotein
Lipid-binding_serum_glycoprotein
Species of bacterium
Its type strain is K5T (=DSM 17306T =VKM B-2378T). Hypoacylated lipopolysaccharide (LPS) from P. cryohalolentis induces moderate TLR4-mediated inflammatory
Psychrobacter_cryohalolentis
American biologist
and biochemical aspects of B lymphocytes responses to bacterial lipopolysaccharides. She completed postdoctoral training in the laboratory of Philip
Kathleen_Kelly_(biologist)
Group of antibiotics derived from fungi
called the outer membrane. The outer membrane is a lipid layer (lipopolysaccharide chain) that blocks passage of water-soluble (hydrophilic) molecules
Penicillin
Protein-coding gene in the species Homo sapiens
component of the TLR4 complex and is induced in a number of cell types by lipopolysaccharide (LPS). The main isoform of the human protein is 811 amino long and
TLR4 interactor with leucine rich repeats
TLR4_interactor_with_leucine_rich_repeats
Species of bacterium
strictly anaerobic, non-motile, non-spore-forming, oval bacterium. The lipopolysaccharide (LPS) of A. muciniphila has been found to lack the O-antigen unit
Akkermansia_muciniphila
Group of poisons produced by molds
Superantigen type II Pore-forming toxin type III AB toxin/AB5 Endotoxin Lipopolysaccharide Lipid A Bacillus thuringiensis delta endotoxin Cry1Ac Cry3Bb1 Other
Aflatoxin
Class of chemical compounds
acylated glucosamine precursors of the lipid A component of the lipopolysaccharides in Gram-negative bacteria. Typical lipid A molecules are disaccharides
Saccharolipid
American physician and infectious diseases researcher
Douek, Daniel C. (November 15, 2014). "Sevelamer Does Not Decrease Lipopolysaccharide or Soluble CD14 Levels But Decreases Soluble Tissue Factor, Low-Density
Annie_Luetkemeyer
Women American scientist
immunology, and biomedical sciences. Known for her research on lipopolysaccharides (LPS), proteasomes, and inflammatory diseases, Dr. Qureshi has contributed
Nilofer_Qureshi
Species of bacteria
Gram negative because of their two external membranes, but they lack lipopolysaccharide and possess many surface lipoproteins, unlike true Gram-negative bacteria
Borrelia_burgdorferi
Species of bacterium
from this bacterium include extracellular enzymes, polysaccharides, lipopolysaccharides, etc. Several strains of Xanthomonas campestris produce an exopolysaccharide
Xanthomonas_campestris
Type of lectin
Superantigen type II Pore-forming toxin type III AB toxin/AB5 Endotoxin Lipopolysaccharide Lipid A Bacillus thuringiensis delta endotoxin Cry1Ac Cry3Bb1 Other
Ricin
Species of bacterium
W.; Zurawski, Daniel V. (30 June 2012). "Extracellular stress and lipopolysaccharide modulate Acinetobacter baumannii surface-associated motility". Journal
Acinetobacter_baumannii
Human protein and coding gene
negative regulation of inflammatory response cellular response to lipopolysaccharide positive regulation of T-helper 2 cell cytokine production signal
NLRP3
Type of protein or peptide
most commonly used mitogens in clinical laboratory medicine are: Lipopolysaccharide toxin from gram-negative bacteria is thymus-independent. They may
Mitogen
Species of bacterium
Superantigen type II Pore-forming toxin type III AB toxin/AB5 Endotoxin Lipopolysaccharide Lipid A Bacillus thuringiensis delta endotoxin Cry1Ac Cry3Bb1 Other
Clostridium_perfringens
Chemical compound
of caffeic acid in humans. Also, caffeic acid treatment attenuated lipopolysaccharide (LPS)-induced sickness behaviour in experimental animals by decreasing
Caffeic_acid
Mammalian protein
host viral process detection of lipopolysaccharide triglyceride homeostasis reverse cholesterol transport lipopolysaccharide-mediated signaling pathway high-density
SCARB1
Species of bacterium
assimilate arabinose. Other differences between these species include lipopolysaccharide composition, colony morphology, and differences in metabolism. Burkholderia
Burkholderia_thailandensis
Mammalian protein found in humans
signaling positive regulation of signal transduction cellular response to lipopolysaccharide positive regulation of T-helper 1 cell differentiation viral process
CD80
Microbiological classification system for genus Salmonella
antigen type is determined based on oligosaccharides associated with lipopolysaccharide. Then the "H" antigen is determined based on flagellar proteins (H
Kauffman–White_classification
Human protein and coding gene
apoptotic signaling pathway inflammatory response cellular response to lipopolysaccharide negative regulation of NF-kappaB transcription factor activity signal
PYCARD
Protein-coding gene in the species Homo sapiens
transporter activity cellular iron ion homeostasis cellular response to lipopolysaccharide ageing cellular response to tumor necrosis factor liver regeneration
Hepcidin
Protein found in humans
SH, Hwang D (November 2000). "Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression
MYD88
Protein-coding gene in the species Homo sapiens
locomotory behavior ageing oligodendrocyte differentiation response to lipopolysaccharide regulation of mitochondrial membrane permeability forebrain development
2',3'-Cyclic-nucleotide 3'-phosphodiesterase
2',3'-Cyclic-nucleotide_3'-phosphodiesterase
Protein-coding gene in the species Homo sapiens
to mycotoxin response to amine response to estradiol response to lipopolysaccharide response to amino acid response to peptide hormone response to steroid
Argininosuccinate synthetase 1
Argininosuccinate_synthetase_1
Class of chemical compounds
F (2012). "Gelatin tannate reduces the proinflammatory effects of lipopolysaccharide in human intestinal epithelial cells". Clinical and Experimental Gastroenterology
Tannate
Bacteria that give a positive result in the Gram stain test
simple diderms lacking lipopolysaccharide, the archetypical diderm bacteria where the outer cell membrane contains lipopolysaccharide, and the diderm bacteria
Gram-positive_bacteria
Chemical compound
"Sialic acid transport in Haemophilus influenzae is essential for lipopolysaccharide sialylation and serum resistance and is dependent on a novel tripartite
N-Acetylneuraminic_acid
Pseudogene in the species Homo sapiens
hydrophobic and amphipathic molecules, such as the acyl carbon chains of lipopolysaccharide found on Gram-negative bacteria, but members of this family may have
BPIFA4P
Family of bacteria
order Chlamydiales. Chlamydiaceae species express the family-specific lipopolysaccharide epitope αKdo-(2→8)-αKdo-(2→4)-αKdo (previously called the genus-specific
Chlamydiaceae
Protein family
bacteria that contain highly sialylated glycan structures such as the lipopolysaccharide of Neisseria meningitidis. Binding to these structures allows the
Siglec
Group of chemical compounds
Superantigen type II Pore-forming toxin type III AB toxin/AB5 Endotoxin Lipopolysaccharide Lipid A Bacillus thuringiensis delta endotoxin Cry1Ac Cry3Bb1 Other
Ciguatoxin
relinquish lip- fat Greek λίπος (lípos) lipolysis, lipophile, lipophilic, lipopolysaccharide, lipoprotein, synaloepha liqu- flow Latin liquere deliquesce, liquefy
List of Greek and Latin roots in English/L
List_of_Greek_and_Latin_roots_in_English/L
Lipid component of lipopolysaccharide endotoxins of gram-negative bacteria
gram-negative bacteria. It is the innermost of the three regions of the lipopolysaccharide (LPS), also called endotoxin molecule, and its hydrophobic nature
Lipid_A
Protein-coding gene in the species Homo sapiens
remodeling negative regulation of cellular extravasation response to lipopolysaccharide regulation of vascular permeability brain development negative regulation
ABR, RhoGEF and GTPase activating protein
ABR,_RhoGEF_and_GTPase_activating_protein
Protein-coding gene in the species Homo sapiens
to redox state positive regulation of blood pressure response to lipopolysaccharide peptidyl-cysteine S-nitrosylation response to nitrosative stress formaldehyde
ADH5
American immunologist and geneticist
innate immunity." Beutler discovered the long-elusive receptor for lipopolysaccharide (LPS; also known as endotoxin). He did so by identifying spontaneous
Bruce_Beutler
tuberculosis and the product is incorporated into methylglucose lipopolysaccharides. Enzyme 3.1.3.85 at KEGG Pathway Database. Costa J, Empadinhas N
Glucosyl-3-phosphoglycerate phosphatase
Glucosyl-3-phosphoglycerate_phosphatase
Mammalian protein, acts as a multifunctional hormone
excessive inflammatory responses triggered by bacterial products such as lipopolysaccharide (LPS), potentially by competing for TLR4 binding or directly neutralizing
Resistin
Foodborne illness
Superantigen type II Pore-forming toxin type III AB toxin/AB5 Endotoxin Lipopolysaccharide Lipid A Bacillus thuringiensis delta endotoxin Cry1Ac Cry3Bb1 Other
Ciguatera_fish_poisoning
Protein-coding gene in humans
establishment of blood-nerve barrier response to toxic substance response to lipopolysaccharide hyperosmotic salinity response response to ethanol xenobiotic transport
CLDN1
Antimicrobial compound
reaction denatures the endotoxins and complex polysaccharide and lipopolysaccharide components of the bacterial cell wall and inactivates susceptible
Taurolidine
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