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Form of agglutination in red blood cells
Hemagglutination, or haemagglutination, is a specific form of agglutination that involves red blood cells (RBCs). It has two common uses in the laboratory:
Hemagglutination
Measure of virus or bacteria concentration
The hemagglutination assay or haemagglutination assay (HA) and the hemagglutination inhibition assay (HI or HAI) were developed in 1941–42 by American
Hemagglutination_assay
Carbohydrate-binding protein
legume seeds have been proven to contain high lectin activity, termed hemagglutination. Soybean is the most important grain legume crop in this category.
Lectin
Topics referred to by the same term
social science method Hormonal imprinting, a biological phenomenon Hemagglutination inhibition, method for quantifying the relative concentration of viruses
HI
Type of antibody response
precipitated. Hemagglutination is the process by which red blood cells agglutinate, meaning clump or clog. The agglutin involved in hemagglutination is called
Agglutination_(biology)
Biochemical test for syphilis
test for syphilis is the Treponema pallidum hemagglutination assay or TPHA. TPHA is an indirect hemagglutination assay used for the detection and titration
Treponema pallidum particle agglutination assay
Treponema_pallidum_particle_agglutination_assay
Hemagglutinin of influenza virus
Influenza hemagglutinin (HA) or haemagglutinin[p] (British English) is a homotrimeric glycoprotein found on the surface of influenza viruses and is integral
Hemagglutinin_(influenza)
Determine the concentration of a virus
result of hemagglutination units (HAU), with typical PFU to HAU ratios in the 106 range. This assay takes ~1–2 hours to complete. The hemagglutination inhibition
Virus_quantification
to be more sensitive than DID. Three additional techniques, passive hemagglutination, enzyme linked immunosorbent assay (ELISA), and western blotting (WB)
Extractable_nuclear_antigen
Substance that causes red blood cells to agglutinate
result due to hemagglutination has been inhibited. On the contrary, if hemagglutination occurs, the test will result negative. Hemagglutination blood typing
Hemagglutinin
Topics referred to by the same term
(influenza) (HA), an antigenic glycoprotein from Influenza viruses Hemagglutination assay, a measurement of viruses or bacteria Hartree, an atomic unit
Ha
Species of virus
relatively stringent serologic tests such as virus neutralization (VN) and hemagglutination inhibition (HI). The biophysical and biochemical properties of PPV
Porcine_parvovirus
Infectious disease
natural infection or vaccination. Common serological assays include hemagglutination inhibition assays that detect HA-specific antibodies, virus neutralization
Influenza
American virologist and science administrator
known for inventing the hemagglutination assay, a simple method for quantifying viruses, and adapting it into the hemagglutination inhibition assay, which
George_Hirst_(virologist)
Protozoan parasitic disease
using methods including the Sabin–Feldman dye test (DT), the indirect hemagglutination assay, the indirect fluorescent antibody assay (IFA), the direct agglutination
Toxoplasmosis
Antigen
formation of agglutinins in the body and leads to agglutination, such as hemagglutination, which involves red blood cells (RBCs). The kind of agglutinogens present
Agglutinogen
Anaerobic parasitic protist
identification to species level); enzyme immunoassay (EIA); indirect hemagglutination (IHA); Antigen detection – monoclonal antibody; PCR for species identification
Entamoeba_histolytica
Blood test for syphilis
fluorescent treponemal antibody-absorption (FTA-ABS) test, T. pallidum hemagglutination assays (TPHA), and the microhemagglutination assay (MHA-TP).[citation
Venereal Disease Research Laboratory test
Venereal_Disease_Research_Laboratory_test
(HN) is involved in viral attachment and thus hemadsorption and hemagglutination. Furthermore, the fusion (F) protein is important in aiding the fusion
Human_parainfluenza_viruses
Testing to identify incompatibilities between blood types
procedure may not provide a conclusive identification. In these cases, hemagglutination inhibition can be used, wherein a neutralizing substance cancels out
Blood_compatibility_testing
Infection caused by Bacillus anthracis bacteria
identify B. anthracis includes gamma bacteriophage testing, indirect hemagglutination, and enzyme-linked immunosorbent assay to detect antibodies. The best
Anthrax
Class of viruses which are transmitted by arthropods
complement fixation, polymerase chain reaction, neutralization test, and hemagglutination-inhibition test. In the past, arboviruses were organized into one of
Arbovirus
Way of expressing concentration
abolish the positive test. Many traditional serological tests such as hemagglutination or complement fixation employ this principle. Such tests can typically
Titer
Distinct variation within a species of bacteria or virus or among immune cells
the immune system as foreign, causing an immune response, such as hemagglutination. Serotypes differ widely between individuals; therefore, if cells from
Serotype
Topics referred to by the same term
dedicated to raising cardiovascular and stroke health awareness Indirect Hemagglutination Test, A form of agglutination test that involves red blood cells Ingeniørhøjskolen
IHA
Species of virus
viruses are incomplete. Antigenic drift occurs in influenza A, B, and C. Hemagglutination inhibition experiments using ferret serum after infection allowed the
Influenza_B_virus
Blood disorder in which cold sensitive antibodies target red blood cells
Cold hemagglutination was first reported by Landsteiner in 1903 and found to occur in human beings in 1918. The association of cold hemagglutination with
Cold_agglutinin_disease
Species of plant
Properties and Biomedical Applications, 1998, p. 211; Nagda and Deshmukh, "Hemagglutination Pattern of Galactose Specific Lectin From Pedilanthus tithymaloides
Euphorbia_tithymaloides
Parasitic disease of tapeworms of the Echinococcus type
imaging is the main method—while serology tests (such as indirect hemagglutination, ELISA (enzyme-linked immunosorbent assay), immunoblots, or latex agglutination)
Echinococcosis
British virologist
Her main research areas include influenza vaccination and influenza hemagglutination inhibition. In 1984, Zambon earned a PhD from the University of London
Maria_Zambon
Human disease
labeled as KFD-positive cases. Other methods of diagnosis included hemagglutination inhibition (HI), complement fixation, neutralization tests. However
Kyasanur_Forest_disease
Laboratory methods for determining whether a virus infection has occurred in an organism
(10): 75–83. doi:10.1016/j.amjmed.2005.07.024. PMID 16271546. "Influenza hemagglutination inhibition assay". www.virology.ws. Retrieved 19 October 2020.
Laboratory diagnosis of viral infections
Laboratory_diagnosis_of_viral_infections
Human disease caused by paramyxovirus
Antibody titers can also be measured with complement fixation tests, hemagglutination assays, and neutralization tests. In vaccinated people, antibody-based
Mumps
Contagious virus mainly affecting dogs
made through detection of CPV2 in the feces by either an ELISA or a hemagglutination test, or by electron microscopy. PCR has become available to diagnose
Canine_parvovirus
Study of viruses
to confirm this. Older methods included complement fixation tests, hemagglutination inhibition and virus neutralisation. Newer methods use enzyme immunoassays
Virology
Species of bacterium
Polymerase chain reaction (PCR) detection of M. ovipneumoniae, indirect hemagglutination (IH), and competitive enzyme-linked immunosorbent assay (cELISA) detection
Mycoplasma_ovipneumoniae
Test for syphilis
monoclonal antibodies and immunofluorescence, including T. pallidum hemagglutination assay (TPHA) and fluorescent treponemal antibody absorption (FTA-ABS)
Rapid_plasma_reagin
Species of bacterium
strains are grouped into three primary serovars, A, B, and C, based on hemagglutination inhibition tests. This classification is epidemiologically important
Avibacterium_paragallinarum
Genus of viruses
numerous serologic reactions and tests including neutralization and hemagglutination inhibition. The alphaviruses show various degrees of antigenic cross-reactivity
Alphavirus
Human blood group system
; Marcus, D. M.; Estes, M. K. (2003). "Norwalk virus-like particle hemagglutination by binding to h histo-blood group antigens". Journal of Virology. 77
Lewis_antigen_system
Topics referred to by the same term
class Hellenic Aerospace Industry Helicopter Association International Hemagglutination inhibition assay Haï, a book by Jean-Marie Gustave Le Clézio Hái!,
HAI
Insect cell line
H1N1 influenza virus-like particles produced in insect cells induce hemagglutination inhibiting antibodies in BALB/c mice". Biotechnology Journal. 5 (1):
High_Five_cells
Vaccine against influenza
antigenically distinct viral isolates compared to other vaccines in the hemagglutination-inhibition assay (HIA). A gene-based DNA vaccine, used to prime the
Influenza_vaccine
British Medical Research Council unit
lifecycles, and possible vaccines. A key finding was the level of the Hemagglutination assay that could be used as Correlates of immunity for influenza vaccines
Common_Cold_Unit
Genus of algae
intertidal to 60m. Avrainvillea erecta was reported to have strong hemagglutination activity. In addition, the chloroform fraction of a methanol extract
Avrainvillea
Medical condition
and cell culture (Vero Cells) Serological assay methods, such as HI (hemagglutination inhibition), NT (neutralization test), and CF (complement fixation
Oropouche_fever
Laboratory test for virus-neutralizing antibodies
cause many diseases. It has a higher sensitivity than other tests like hemagglutination and many commercial Enzyme immunoassay without compromising specificity
Plaque reduction neutralization test
Plaque_reduction_neutralization_test
Test based on scientific data to determine if a person is pregnant
introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination inhibition. This was a first step away from in-vivo pregnancy testing
Pregnancy_test
Protein family
disulfide-linked homodimer of two subunits; the dimeric form is essential for hemagglutination activity. The sea urchin egg lectin (SUEL) forms a new class of lectins
Galactose binding lectin domain
Galactose_binding_lectin_domain
Species of virus
influenza D virus were detected in serum samples from humans; however, hemagglutination-inhibiting antibodies against influenza D virus have been detected
Influenza_D_virus
Overview of and topical guide to immunology
Immunofluorescence TINIA FPIA CEDIA SOFIA Rapid test SPR_IA SERS_IA Agglutination Hemagglutination/Hemagglutinin Coombs test Latex fixation test Other Diagnostic immunology
Outline_of_immunology
Australian virologist (1899–1985)
research; he developed techniques to grow and study the virus, including hemagglutination assays. He worked on a live vaccine against influenza, but the vaccine
Macfarlane_Burnet
Species of sea urchin
with the transmission of signals at nerve endings as well as cause hemagglutination (clumping of the red blood cells). When administered to guinea pigs
Toxopneustes_pileolus
Species of virus
present. Other tests include various fluorescence assays, indirect hemagglutination, (PCR) and latex agglutination. An ELISA technique for CMV-specific
Human_cytomegalovirus
Species of virus
virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity"
Adeno-associated_virus
Species of bacterium
MD, Hollingdale MR, Vinson JW, Costa J (December 1976). "A passive hemagglutination test for diagnosis of trench fever due to Rochalimaea quintana". The
Bartonella_quintana
Species of bacterium
to diagnose M. gallisepticum: serum plate agglutination (SPA) test, hemagglutination inhibition test (HI), or enzyme-linked immunosorbent assay (ELISA)
Mycoplasma_gallisepticum
Inflammatory lung disease
the presence of rheumatoid factor (an indicator of autoimmunity). Hemagglutination, a clumping of red blood cells in response to the presence of antibodies
Diffuse_panbronchiolitis
Tropical disease caused by the oomycete Pythium insidiosum
Piromsontikorn S, Srimuang S, Khupulsup K, Krajaejun T (July 2009). "Hemagglutination Test for Rapid Serodiagnosis of Human Pythiosis". Clin. Vaccine Immunol
Pythiosis
Class of keto acid sugars
cell membranes of the upper respiratory tract. This is the basis of hemagglutination when viruses are mixed with blood cells, and entry of the virus into
Sialic_acid
Genus of plants
stenodactylin, and volkensin, which are toxic to cells. They cause apoptosis, hemagglutination, inhibition of protein synthesis, and depurination of ribosomes and
Adenia
Genus of viruses in the family Orthomyxoviridae
frequently. Diagnosis is by virus isolation, serology, and other tests. Hemagglutination inhibition (HI) is one method of serology that detects antibodies for
Influenza_C_virus
Species of virus
reaction (RT-PCR), isolation from tissue cultures, immunohistochemistry, hemagglutination inhibition (of paired samples) or complement fixation (of paired samples)
Western equine encephalitis virus
Western_equine_encephalitis_virus
Sendai virus, virus of rodents
immunofluorescence, and hemagglutination assays, with particular emphasis on use of the ELISA for its high sensitivity (unlike the hemagglutination assay) and its
Murine_respirovirus
Subfamily of viruses
protein C. Avulaviruses can be separated into distinct serotypes using hemagglutination assay and neuraminidase assay. All avulaviruses hemagglutinate chicken
Avulavirinae
Human blood group system
Sd(a) phenotyping. The Sd(a) antigen can be detected in urine using hemagglutination inhibition testing: anti-Sd(a) is added to the urine, followed by Sd(a)
Sid_blood_group_system
Species of virus
made worse by concurrent GI infections. Immunofluorescence (IF), PCR, hemagglutination, ELISA and electron microscopy can be used to identify the virus. Aborted
Ungulate_bocaparvovirus_1
Medical condition
most state diagnostic laboratories were complement-fixation test and hemagglutination inhibition tests with La Crosse virus, but these failed to detect antibody
Jamestown_Canyon_encephalitis
Protein found in humans
fibrosis. In invertebrate, dermatopontin homologue plays a role in hemagglutination, cell–cell aggregation, and expression during parasite infection. Dermatopontin
Dermatopontin
Japanese company
founded in Tokyo, Japan. 1966: Launch of HA Ag (TPHA), the world's first hemagglutination test for syphilis. 1981: Established Fujirebio Taiwan Inc. 1987: Established
Fujirebio
German virologist (born 1980)
Albert Heim: Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular
Ijad_Madisch
American virologist
(1955): 226-230. Buckley, Sonja M. "Propagation, Cytopathogenicity, and Hemagglutination-Hemadsorption of Some Arthropodborne Viruses in Tissue Culture." NYASA
Sonja_Buckley
Food that aids immunity against a disease
example, experimental animals were given transgenic bananas with anti-hemagglutination specific antibodies to combat measles. It was found that the bananas
Edible_vaccine
Alteration of displayed antigens by pathogens
virus transmission. The ability of an antiviral antibody to inhibit hemagglutination can be measured and used to generate a two-dimensional map using a
Antigenic_variation
Genus of viruses
now available such as hemagglutination (HA), enzyme-linked immunosorbent assay (ELISA), immune electron microscopy, hemagglutination-inhibition tests (HA/HI)
Torovirus
Clinical trials of influenza vaccine
responses (seroconverion and seroprotection rates of 86% to 100%) based on hemagglutination inhibition assay (HAI) at all doses tested. The unadjuvanted vaccine
H5N1_vaccine_clinical_trials
Classification of leukocyte antigens
have induced the dominant allo-reactive antibody in the recipient. Hemagglutination assay. In generating an immune response to an antigen, the B-cells
History and naming of human leukocyte antigens
History_and_naming_of_human_leukocyte_antigens
880.225 – cytopathogenic effect, viral MeSH G04.185.515.880.420 – hemagglutination, viral MeSH G04.185.515.880.450 – inclusion bodies, viral MeSH G04
List_of_MeSH_codes_(G04)
Finnish urologist and surgeon
Sarna-Ahava-Leppo; Current Chemotherapy, Washington DC 1978. Mannose-resistant hemagglutination and P antigen recognition characteristic of E. soli causing primary
Jaakko_Elo
Swedish medical doctor
Gemzell and Leif Wide presented a pregnancy test based on in-vitro hemagglutination inhibition, a first step away from in-vivo pregnancy testing. This
Carl_Axel_Gemzell
Canadian bacteriologist
he was awarded a Master of Science degree in 1965 for research on hemagglutination in adenovirus. He went on to complete a PhD on bacterial fertility
Mark_Achtman
American professor of microbiology
Brand, K. G.; Syverton, J. T. (1962). "Results of Species-Specific Hemagglutination Tests on "Transformed," Nontransformed, and Primary Cell Cultures"
Jerome_T._Syverton
Genus of viruses
found to cause high levels of syncytium formation but did not cause hemagglutination in human red blood cells (RBCs). In reptiles the virus has been found
Orthoreovirus
American microbiologist (1921–2016)
C.; Sampson, Calvin C.; Faggett, Timothy (1981). "A Rapid Passive Hemagglutination Method For Demonstrating Serum Antibodies to Candida Albicans". J Natl
George_C._Royal
450.495.735.050 – agglutination tests MeSH E01.450.495.735.050.375 – hemagglutination tests MeSH E01.450.495.735.050.375.150 – coombs test MeSH E01.450.495
List_of_MeSH_codes_(E01)
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