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Protein-coding gene in the species Homo sapiens
Endothelin-3 is a protein that in humans is encoded by the EDN3 gene. The protein encoded by this gene is a member of the endothelin family. Endothelins
Endothelin_3
Vasoconstricting peptide family
genes for endothelin-1 (ET-1), endothelin-2 (ET-2), and endothelin-3 (ET-3) are located on chromosomes 6, 1, and 20, respectively. Endothelin functions
Endothelin
Breed of chicken from Indonesia
20th chromosome involving the endothelin 3 gene (EDN3). The roosters weigh 2–2.5 kg (4.4–5.5 lb) and the hens 1.5–2 kg (3.3–4.4 lb). The hens lay tinted
Ayam_Cemani
Human blood group classification
transmembrane zinc-dependent endopeptidase which is responsible for cleaving endothelin-3. The KEL gene encodes a type II transmembrane glycoprotein that is the
Kell_antigen_system
Drug that blocks endothelin receptors
An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: Dual ET Receptor Antagonists, which
Endothelin receptor antagonist
Endothelin_receptor_antagonist
Protein-coding gene in the species Homo sapiens
Yanagisawa and team and belongs to a family of three endothelin peptide isoforms (ET-1, ET-2, ET-3), which constrict blood vessels. ET-2 is encoded by
Endothelin_2
Vasoconstricting peptide
Endothelin 1 (ET-1), also known as preproendothelin-1 (PPET1), is the most potent vasoconstrictor produced by the human body. It is a peptide produced
Endothelin_1
Type of inflammation
calcitonin gene-related peptide (CGRP), neurokinin A (NKA), and endothelin-3 (ET-3). For example, release of neuropeptides can increase vasodilatation
Neurogenic_inflammation
Breed of chicken
Carl-Johan (2016-02-16). "A Complex Genomic Rearrangement Involving the Endothelin 3 Locus Causes Dermal Hyperpigmentation in the Chicken". PLOS Genet. 7
Svarthöna
Chemical compound
the brand name Tyvalzi) is a synthetic analog of endothelin-1 that works as a selective endothelin-B receptor agonist. In May 2023, it was approved in
Sovateltide
Protein-coding gene in the species Homo sapiens
Endothelin receptor type B, (ET-B) is a protein that in humans is encoded by the EDNRB gene. Endothelin receptor type B is a G protein-coupled receptor
Endothelin_receptor_type_B
Chemical compound
both endothelin A and endothelin B receptors. Aprocitentan was approved for medical use in the United States in March 2024. It is the first endothelin receptor
Aprocitentan
Chemical compound
the treatment of pulmonary hypertension. It is an endothelin receptor antagonist. The peptide endothelin constricts muscles in blood vessels, increasing
Ambrisentan
Protein toxin family
derivations of previously mentioned ones. The main differences in the family of endothelin and sarafotoxins appear at N-terminal of peptides, as C-terminal in all
Sarafotoxin
Human chromosome
protein EDEM2: ER degradation-enhancing alpha-mannosidase-like 2 EDN3: endothelin 3 ENTPD6: Ectonucleoside triphosphate diphosphohydrolase 6 ESF1: ESF1 nucleolar
Chromosome_20
Chemical compound
Macitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist developed by Actelion and approved for the treatment of pulmonary arterial
Macitentan
Medication
Bosentan, sold under the brand name Tracleer among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery
Bosentan
G protein-coupled receptor
There are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation
Endothelin_receptor
Protein-coding gene in the species Homo sapiens
Matsumoto M, Suzuki R, Matsuda T, Watanabe E, et al. (April 2013). "Endothelin-3 expression in the subfornical organ enhances the sensitivity of Na(x)
SCN7A
Endothelin-converting enzyme 1 (EC 3.4.24.71, endothelin-converting enzyme, ECE-1) is an enzyme. This enzyme catalyses the following chemical reaction
Endothelin-converting enzyme 1
Endothelin-converting_enzyme_1
Group of autoimmune diseases resulting in abnormal growth of connective tissue
decrease collagen degradation and increase extracellular matrix production. Endothelin signalling is implicated in the pathophysiology of fibrosis. Vitamin D
Scleroderma
Topics referred to by the same term
the implementation of Evacuated Tube Transport (ETT) Endothelin 3, a protein, member of endothelin family This disambiguation page lists articles associated
ET3
Chemical compound
experimental anti-cancer drug candidate in development by AstraZeneca. It is an endothelin receptor antagonist. Zibotentan was granted fast track status for the
Zibotentan
Chemical compound
BQ-123 is a selective ETA endothelin receptor antagonist. As such, it is used as a biochemical tool in the study of endothelin receptor function. BQ-123
BQ-123
Chemical compound
brand name Pivlaz) is a drug belonging to the class of endothelin receptor antagonists. The endothelin 1 receptor is one of the strongest known vasoconstrictors
Clazosentan
Medical condition
hormones; angiotensin II, endothelin-1 and the catecholamines (e.g. noradrenaline).[citation needed] Angiotensin-II and endothelin-1 are hormones that bind
Right_ventricular_hypertrophy
High blood pressure in the pulmonary arteries
vasodilation. Endothelin receptor antagonists cause vasodilation as well by blocking the action of the potent vasoconstrictor endothelin-1. Prostacyclins
Pulmonary arterial hypertension
Pulmonary_arterial_hypertension
Increased blood pressure in lung arteries
(March 2021). "Endothelin receptor antagonists for pulmonary arterial hypertension". The Cochrane Database of Systematic Reviews. 2021 (3) CD004434. doi:10
Pulmonary_hypertension
276.249 – endothelins MeSH D12.644.276.249.225 – endothelin-1 MeSH D12.644.276.249.235 – endothelin-2 MeSH D12.644.276.249.245 – endothelin-3 MeSH D12
List_of_MeSH_codes_(D12.644)
Chemical compound
of endothelin (ET) on the endothelin-A (ETA) receptor selectively (by a factor of 6000 compared with the ETB). It is a sulfonamide class endothelin receptor
Sitaxentan
Genetic disorder in horses
to Hirschsprung's disease in humans. A mutation in the middle of the endothelin receptor type B (EDNRB) gene causes lethal white syndrome when homozygous
Lethal_white_syndrome
Cell surface receptors
hormone Sauvagine Urocortin Antagonists Astressin-B Agonists Endothelin 1 Endothelin 2 Endothelin 3 IRL-1620 Sarafotoxin Antagonists A-192621 Ambrisentan Aprocitentan
Signaling_peptide_receptor
Mammalian protein found in Homo sapiens
endothelial cells. Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1), -2 (EDN2), and -3 (EDN3) to biologically
Endothelin converting enzyme 1
Endothelin_converting_enzyme_1
Chemical compound
brand name Vanrafia, is a medication used to reduce proteinuria. It is an endothelin receptor antagonist. It is taken by mouth. Atrasentan was approved for
Atrasentan
Japanese molecular biologist
molecular biologist and physician, famous for his discovery of the hormone endothelin and the neuropeptide orexin, the absence of which is the cause of narcolepsy
Masashi_Yanagisawa
Urocortin Antagonists: Astressin-B See here instead. Agonists: Endothelin 1 Endothelin 2 Endothelin 3 IRL-1620 Sarafotoxin Antagonists: A-192621 Ambrisentan Aprocitentan
List of signaling peptide/protein receptor modulators
List_of_signaling_peptide/protein_receptor_modulators
24.71: endothelin-converting enzyme 1 EC 3.4.24.72: fibrolase EC 3.4.24.73: jararhagin EC 3.4.24.74: fragilysin EC 3.4.24.75: lysostaphin EC 3.4.24.76:
List_of_EC_numbers_(EC_3)
Medical condition
4A is an extremely rare congenital disorder caused by a mutation in an endothelin receptor gene. It results in common Waardenburg syndrome symptoms such
Waardenburg_syndrome_type_4A
Chemical compound
K; Tigyi, G J; Leffler, C W (1997). "Role of lysophosphatidic acid in endothelin-1-and hematoma-induced alteration of cerebral microcirculation". American
Lysophosphatidic_acid
Medical condition
(3) C – cell migration disorder of the neurocytes of the gut, and (4) D – sensorineural deafness. The syndrome is caused by mutation in the endothelin
ABCD_syndrome
Physiological processes of hypertension
sympathetic drive in hypertension include reactive oxygen species and endothelin. Some studies have shown that hypertensive patients manifest greater vasoconstrictor
Pathophysiology of hypertension
Pathophysiology_of_hypertension
Medical condition
prostacyclin and thromboxane (from Kupffer cells) or nitric oxide (NO) and endothelin-1 (ET-1). ET-1 is the most potent vasoconstrictor under investigation
Portopulmonary_hypertension
Swiss biopharmaceutical company
treatment. Actelion scientists were among the first to work in the field of endothelin receptor antagonists. Actelion was initially financed with venture capital
Actelion
Medication
nephropathy and focal segmental glomerulosclerosis. Sparsentan is an endothelin and angiotensin II receptor antagonist. It is taken by mouth. The most
Sparsentan
Genetic condition involving hearing loss and depigmentation
American Paint Horses by phenotype, brainstem auditory-evoked responses, and endothelin receptor B genotype". Journal of the American Veterinary Medical Association
Waardenburg_syndrome
Ballooning or rupturing of a blood vessel in the brain
perlecan, elastin, collagen type 1 A2, endothelial nitric oxide synthase, endothelin receptor A and cyclin dependent kinase inhibitor. Recently, several genetic
Intracranial_aneurysm
Bleeding into the brain's subarachnoid space
cerebrospinal fluid (CSF) causes vasoconstriction by increasing free radicals, endothelin-1, prostaglandin and reducing the level of nitric oxide and prostacyclin
Subarachnoid_hemorrhage
Protein-coding gene in the species Homo sapiens
Endothelin receptor type A, also known as ETA, is a human G protein-coupled receptor. Endothelin receptor type A has been shown to interact with HDAC7A
Endothelin_A_receptor
Chemical compound
BQ-788 is a selective ETB antagonist. Endothelin Okada, M; Nishikibe, M (Winter 2002). "BQ-788, a selective endothelin ET(B) receptor antagonist". Cardiovascular
BQ-788
Disorder of depression and mood episodes
signaling, cardiac hypertrophy signaling, Wnt signaling, Notch signaling, and endothelin 1 signaling. Of the 16 genes identified in these pathways, three were
Bipolar_disorder
Chemical compound
Tazi KA, Barriere E, Poirel O, et al. (December 2004). "Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic
Tezosentan
Class of enzymes important in regulating DNA transcription
Histone deacetylases (EC 3.5.1.98, HDAC) are a class of enzymes that remove acetyl groups (O=C-CH3) from an ε-N-acetyl lysine amino acid on both histone
Histone_deacetylase
Narrowing of blood vessels due to the constriction of smooth muscle cells
vasoconstriction, including the release of vasoconstrictor substances such as endothelin and angiotensin II, both of which play crucial roles in the modulation
Vasoconstriction
Medication
treatment of pulmonary arterial hypertension. It contains macitentan, an endothelin receptor antagonist (ERA); and tadalafil, a phosphodiesterase 5 (PDE5)
Macitentan/tadalafil
Measurable indicators of diabetes
with prediabetes or Type 2 diabetes mellitus. Oxytocin (OXT) Omentin Endothelin-1 Nesfatin-1 Irisin Betatrophin Hepatocyte growth factor (HGF) Fibroblast
Biomarkers_of_diabetes
Anti-nausea group of medications
Brian J.; Sanger, Gareth J. (1993). 5-Hydroxytryptamine-3 Receptor Antagonists. CRC Press. pp. 2–3. ISBN 978-0-8493-5463-2. Galvan, M.; Gittos, M.; Fatmi
5-HT3_antagonist
Coloration of animal coat/fur
"Canine coat pigmentation genetics: a review". Animal Genetics. 53 (1): 3–34. doi:10.1111/age.13154. Retrieved August 21, 2024. Dreger, Dayna L.; Schmutz
Points_(coat_color)
Substance that binds to a receptor to change its response to stimuli
lowered or left unaffected (3 and 3 possibilities). This yields 17 possible modulator combinations. There are 18 (=2*3*3) if neutral modulator type is
Allosteric_modulator
Medical condition
(February 2014). "Astrocyte-Derived Endothelin-1 Inhibits Remyelination through Notch Activation". Neuron. 81 (3): 588–602. doi:10.1016/j.neuron.2013
CARASAL
Term referring to actions upon a blood vessel that alter its diameter
α-adrenergic receptors predominate in smooth muscle of resistance vessels. Endothelin, and angiotensin are the vasoconstrictors of smooth muscles while nitric
Vasomotor
Inner layer of blood vessel
been shown to release local chemicals called endothelins which are powerful vasoconstrictors. Endothelins help to regulate capillary exchange and alter
Tunica_intima
Impaired function of the inner lining of blood/lymph vessels
stress by releasing mediators, such as nitric oxide, prostacyclin and endothelin, and by controlling local angiotensin-II activity. Dysfunctional endothelium
Endothelial_dysfunction
carotid artery occlusion (in some species only) Focal cerebral ischemia Endothelin-1-induced constriction of arteries and veins Middle cerebral artery occlusion
Animal model of ischemic stroke
Animal_model_of_ischemic_stroke
Medical condition in which spasm of arteries causes episodes of reduced blood flow
ischemia and pulmonary hypertension in Raynaud's phenomenon, and the endothelin receptor antagonist bosentan is used to manage severe pulmonary hypertension
Raynaud_syndrome
Color pattern in horses
DNA test developed, is produced by the Ile118Lys mutation on the equine Endothelin receptor type B gene and when homozygous produces lethal white syndrome
Sabino_horse
Protein-coding gene in the species Homo sapiens
Hydroxycarboxylic acid receptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B, is a protein which in humans is encoded by the HCAR3 gene
Hydroxycarboxylic acid receptor 3
Hydroxycarboxylic_acid_receptor_3
Fibrous tissue in the heart
chemokines of the CC and CXC families, angiotensin II, norepinephrine, endothelin, natriuretic peptides, and platelet-derived growth factors". Both the
Myocardial_scarring
Chemical compound
Darusentan (LU-135252; HMR-4005) is an endothelin receptor antagonist. Gilead Colorado, a subsidiary of Gilead Sciences, under license from Abbott Laboratories
Darusentan
Chemical compound
Lisa; Marsh, Kennan C. (1996). "2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ETASelective Endothelin Receptor Antagonists. 1. Discovery of A-127722". Journal
Piperonal
Mammalian protein found in Homo sapiens
The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. Actions
Beta-3_adrenergic_receptor
Mammalian protein
2003-1695. PMID 15090463. Casey ML, MacDonald PC (October 1996). "The endothelin-parathyroid hormone-related protein vasoactive peptide system in human
Parathyroid hormone-related protein
Parathyroid_hormone-related_protein
Endocrine gland in the brain of most vertebrates
The pineal gland contains receptors for the regulatory neuropeptide, endothelin 1, which, when injected in picomolar quantities into the lateral cerebral
Pineal_gland
Medical condition of the cerebral arteries
vasodilators (like nitric oxide and prostacyclin) and vasoconstrictors (like endothelin). In vasospasm, endothelial damage disrupts this balance, reducing vasodilator
Cerebral_vasospasm
Class of receptors
B1 B2 Chemerin 1 2 Chemokine Cholecystokinin A B Endothelin A B Formyl peptide 1 2 3 FSH Galanin 1 2 3 Gonadotropin-releasing hormone 1 2 Ghrelin Kisspeptin
Gonadotropin_receptor
Organ that connects the fetus to the uterine wall
intermingling of fetal and maternal blood occurs ("placental barrier"). Endothelin and prostanoids cause vasoconstriction in placental arteries, while nitric
Placenta
Category of drug
of muscimol as γ-aminobutyric acid(a) receptor agonists". J Med Chem. 56 (3): 993–1006. doi:10.1021/jm301473k. PMID 23294161. Löscher W, Rogawski MA (December
GABA_receptor_agonist
Cardiac hormone which increases renal sodium excretion
concentration is not the direct stimulus for increased ANP secretion Endothelin, a potent vasoconstrictor Recently, it was discovered that ANP also can
Atrial_natriuretic_peptide
Protein-coding gene in the species Homo sapiens
B1 B2 Chemerin 1 2 Chemokine Cholecystokinin A B Endothelin A B Formyl peptide 1 2 3 FSH Galanin 1 2 3 Gonadotropin-releasing hormone 1 2 Ghrelin Kisspeptin
GPR21
Protein-coding gene in the species Homo sapiens
protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392
GPR62
Type of localized bleeding in tissues outside blood vessels
pressure or be asymptomatic. The damaged capillary endothelium releases endothelin, a hormone that causes narrowing of the blood vessel to minimize bleeding
Bruise
Sensory structure in the brain
division, and the ventromedial core segment. The subfornical organ contains endothelin receptors mediating vasoconstriction and high rates of glucose metabolism
Subfornical_organ
Medication
cause sympathetic activation, and release of vasoconstrictors such as endothelin and angiotensin II. Parker JD (February 2004). "Nitrate tolerance, oxidative
Nitroglycerin_(medication)
Indian biophysicist (born 1944)
targets such as phospholipase A2, cyclooxygenase, lipoxygenase, endothelin receptor, endothelin converting enzyme, breast cancer regression proteins and matrix
Tej_P._Singh
Protein-coding gene in the species Homo sapiens
Latrophilin 3 is a protein that in humans is encoded by the ADGRL3 gene. This gene encodes a member of the latrophilin subfamily of G protein-coupled
Latrophilin_3
Chemical compound
I), Carboxypeptidase M, Neutral endopeptidase 24.15, Endothelin converting enzyme-1, Endothelin converting enzyme-2. Bradykinin is a potent endothelium-dependent
Bradykinin
Mammalian protein found in Homo sapiens
activity against signaling peptides such as enkephalins, substance P, endothelin, and atrial natriuretic peptide. Associations have been observed between
Neprilysin
Layer of cells that line the inner surface of blood vessels
assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension". Journal
Endothelium
Found in insects that play a role in aging and reproduction
B1 B2 Chemerin 1 2 Chemokine Cholecystokinin A B Endothelin A B Formyl peptide 1 2 3 FSH Galanin 1 2 3 Gonadotropin-releasing hormone 1 2 Ghrelin Kisspeptin
Methuselah-like_proteins
Involuntary non-striated muscle
invaginations in the sarcoplasm contain a host of receptors (prostacyclin, endothelin, serotonin, muscarinic receptors, adrenergic receptors), second messenger
Smooth_muscle
Chemical compound
causing sympathetic activation and release of vasoconstrictors such as endothelin and angiotensin II which counteract the vasodilation induced by isosorbide
Isosorbide_dinitrate
Protein-coding gene in the species Homo sapiens
peptide stimulates thymidine incorporation in endothelial cells: role of endothelin-1". Am. J. Physiol. Endocrinol. Metab. 285 (2): E390–6. doi:10.1152/ajpendo
Gastric inhibitory polypeptide receptor
Gastric_inhibitory_polypeptide_receptor
Species of fungus
Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes". Scientific Reports
Psilocybe_cubensis
Relationship between biological organs
prolactin, oxytocin, and prostaglandins. Luteolysis involves factors such as endothelin-1 and TNFα, which inhibit steroidogenesis and induce apoptosis. Estrogen
Hypothalamic–pituitary–gonadal axis
Hypothalamic–pituitary–gonadal_axis
Widening of blood vessels
CVPharmacology. Archived from the original on 16 December 2008. Retrieved 3 December 2013. Trammel JE, Sapra A (2024). "Physiology, Systemic Vascular
Vasodilation
Chemical compound
Mechanisms for Contraction to Angiotensin II and Endothelin-1". Journal of the American Society of Hypertension. 3 (2): 84–95. doi:10.1016/j.jash.2008.09.002
Fimasartan
Protein-coding gene in the species Homo sapiens
rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. doi:10.1016/S0014-5793(03)01196-7. PMID 14623098. S2CID 11563502
GPR142
Chemical compound
Thomas N. (2004). "Development of a Scalable Process for CI-1034, an Endothelin Antagonist". Organic Process Research & Development. 8 (2): 201–212. doi:10
Bis(triphenylphosphine)palladium chloride
Bis(triphenylphosphine)palladium_chloride
Cooper, Kim; Gosnell, Kelly (2022-02-09). "Appendix A: Abbreviations". Foundations of Nursing. Elsevier Health Sciences. ISBN 978-0-323-82713-3.
List of medical abbreviations: E
List_of_medical_abbreviations:_E
Protein-coding gene in the species Homo sapiens
have been found to inhibit SUCNCR1 activation include NF-56-EJ40, 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide, and three compounds identified as 2c,
SUCNR1
Type of membrane receptor that acts through a second messenger
B1 B2 Chemerin 1 2 Chemokine Cholecystokinin A B Endothelin A B Formyl peptide 1 2 3 FSH Galanin 1 2 3 Gonadotropin-releasing hormone 1 2 Ghrelin Kisspeptin
Metabotropic_receptor
ENDOTHELIN 3
ENDOTHELIN 3
Surname or Lastname
Americanized form of the Latin personal name Januarius or its Italian derivative Gennaro, which was borne by a number of early Christian saints, most famously a 3rd-century bishop of Benevento who became the patron of Naples.English
Americanized form of the Latin personal name Januarius or its Italian derivative Gennaro, which was borne by a number of early Christian saints, most famously a 3rd-century bishop of Benevento who became the patron of Naples.English : altered form of Janeway.In New England, a translation of French Janvier.
Surname or Lastname
English (Somerset)
English (Somerset) : habitational name from Look in Puncknowle, Dorset, named in Old English with lūce ‘enclosure’.English : possibly a variant of Luck 3.Northern English and Scottish : from a vernacular pet form of Lucas.Dutch (van Look) : topographic name from look ‘enclosure’ or habitational name from a place named with this word.Thomas Look (b. c. 1622) was in Lynn, MA, by 1646. His son, also called Thomas (b. 1646), moved to Martha’s Vineyard about 1670.
Surname or Lastname
English
English : variant of Long 1.German and French (Alsace–Lorraine) : from Middle High German lunge ‘lung’, presumably applied as a nickname.Chinese : variant of Long 3.Chinese : variant of Long 4.
Surname or Lastname
Americanized spelling of German Lutz.English
Americanized spelling of German Lutz.English : patronymic from Lutt, a medieval personal name which probably preserves an Old English byname Lutt(a), derived from l̄t ‘small’ (see Light 3).
Surname or Lastname
English
English : variant spelling of Lyon 1–3.French : variant of Lyon 1.French : habitational name from places in Calvados, Loire, and Meuse named with Lion.
Surname or Lastname
Irish
Irish : variant of Mullen.English : from Old French Milon, an inflected form of the personal name Miles (see Miles 1).English : from Middle English milne, adjectival form of mille ‘mill’, or perhaps a topographic name for someone living in a lane leading to a mill, from Middle English mille, milne ‘mill’ + lane, lone ‘lane’.Dutch : patronymic from Miele 3.
Surname or Lastname
English
English : variant of Mares 2.Dutch : variant of Mares 3.
Surname or Lastname
English
English : habitational name from Loose in Kent or Suffolk, both named from Old English hlÅse ‘pigsty’.Dutch : variant of Loos 3.German : variant of Loos 1.
Surname or Lastname
English
English : patronymic from Low 3 and 4.English : topographic name rom the plural of Middle English lowe ‘mound’, ‘hill’ (see Low 1).
Surname or Lastname
English
English : variant spelling of Mares 2.Dutch : variant of Mares 3.Dutch and Belgian (van Maris) : habitational name for someone from Merris in French Flanders or possibly from Maris in Dutch Limburg.Greek : probably a metronymic from the female personal name Maria.
Surname or Lastname
Chinese
Chinese : variant of Wen 2.Chinese : from a character in the personal name of Hu Gongman, a retainer of Wu Wang. After the latter established the Zhou dynasty in 1122 bc, he granted the state of Chen to Hu Gongman, whose descendants adopted the second character of his given name, Man, as their surname. This character also means ‘Manchurian’, but the name does not appear to be related to this meaning.Chinese : variant of Wen 3.Chinese : variant of Wan 1.English and Jewish : variant spelling of Mann.Dutch : from Middle Dutch man ‘man’, ‘husband’, ‘vassal’, ‘arbiter’.French : from the Germanic personal name Manno (see Mann 2).Jewish (Ashkenazic) : from the personal name Man, derived from Yiddish ‘man’.
Surname or Lastname
Irish
Irish : reduced Anglicized form of Gaelic Mac Fhloinn and Ó Fhloinn (see Flynn).Scottish : variant of Lyne 3.English : habitational name from any of several places so called in Norfolk, in particular King’s Lynn, an important center of the medieval wool trade. The place name is probably from an Old Welsh word cognate with Gaelic linn ‘pool’, ‘stream’.
Surname or Lastname
English
English : nickname for a small man, or distinguishing epithet for the younger of two bearers of the same personal name, from Middle English littel, Old English l̄tel, originally a diminutive of l̄t (see Light 3).Irish : translation of Gaelic Ó Beagáin ‘descendant of Beagán’ (see Begin).Translation of French Petit and Lepetit; also used as an English form of names such as Jean-Petit ‘little John’.Translation of any of various other European name meaning ‘little’.
Surname or Lastname
English
English : patronymic from a variant spelling of Mayer 1.English : variant of Myers.Spanish : variant of Mier 2.Dutch : variant of Mier 3.Dutch (van der Miers) : variant of Meers 2.
Surname or Lastname
English
English : variant of Lyon 3.Irish : variant of Lyon 4.
Surname or Lastname
English
English : patronymic meaning ‘son of the mayor’ (see Mayer 1).Jewish (Ashkenazic) : patronymic from the personal Meyer (see Meyer 2).American form of German Meyer, with excrescent -s.Irish : variant of Meyer 3.
Surname or Lastname
English, French, Danish, Dutch, and German
English, French, Danish, Dutch, and German : from a short form of the personal name Matthias (see Matthew) or any of its many cognates, for example Norman French Maheu.English, French, Dutch, and German : from a nickname or personal name taken from the month of May (Middle English, Old French mai, Middle High German meie, from Latin Maius (mensis), from Maia, a minor Roman goddess of fertility). This name was sometimes bestowed on someone born or baptized in the month of May; it was also used to refer to someone of a sunny disposition, or who had some anecdotal connection with the month of May, such as owing a feudal obligation then.English : nickname from Middle English may ‘young man or woman’.Irish (Connacht and Midlands) : when not of English origin (see 1–3 above), this is an Anglicized form of Gaelic Ó Miadhaigh ‘descendant of Miadhach’, a personal name or byname meaning ‘honorable’, ‘proud’.French : habitational name from any of various places called May or Le May.Jewish (Ashkenazic) : habitational name from Mayen, a place in western Germany.Americanized spelling of cognates of 1 in various European languages, for example Swedish Ma(i)j.Chinese : possibly a variant of Mei 1, although this spelling occurs more often for the given name than for the surname.Cape May, at the mouth of Delaware Bay, is named after the Dutch explorer Cornelius Jacobsen May.
Surname or Lastname
English, Scottish, and Irish
English, Scottish, and Irish : variant of Love 1–3.Dutch : from Luffo, a pet form a personal name such as Ludolph.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : via Old French from the Germanic personal name Milo, of unknown etymology. The name was introduced to England by the Normans in the form Miles (oblique case Milon). In English documents of the Middle Ages the name sometimes appears in the Latinized form Milo (genitive Milonis), although the normal Middle English form was Mile, so the final -s must usually represent the possessive ending, i.e. ‘son or servant of Mile’.English : patronymic from the medieval personal name Mihel, an Old French contracted form of Michael.English : occupational name for a servant or retainer, from Latin miles ‘soldier’, sometimes used as a technical term in this sense in medieval documents.Irish (County Mayo) : when not the same as 1 or 3, an Anglicized form of Gaelic Ó Maolmhuire, Myles being used as the English equivalent of the Gaelic personal name Maol Muire (see Mullery).Jewish (eastern Ashkenazic) : unexplained.Dutch : variant of Miels, a variant of Miele 3.John Miles or Myles (c.1621–83), born probably in Herefordshire, England, was a pioneer American Baptist minister who emigrated to New England in 1662 and had a pastorate in Swansea, MA. Many of his descendants spell their name Myles.
Surname or Lastname
English
English : patronymic from Mayer 1.German : patronymic from Mayer 2.Dutch : variant of Meyer 1 and 3.
ENDOTHELIN 3
ENDOTHELIN 3
Girl/Female
Hindu
Hope, Waiting for something
Girl/Female
Australian, Indian
Knowledge
Girl/Female
Hindu, Indian
Gem of a King
Boy/Male
Teutonic
Lord of the home.
Boy/Male
Arabic
Pleasure; High Spirits
Male
Russian
Variant spelling of Russian Sergei, possibly SERGEJ means "sergeant."Â
Surname or Lastname
English
English : variant of Garrett 1.German : from the Germanic personal name Gerwald, composed of the elements gÄr, gÄ“r ‘spear’, ‘lance’ + wald- ‘rule’.
Girl/Female
Hindu, Indian
Individual
Boy/Male
Hindu, Indian, Punjabi, Sikh
A God-like Person
Boy/Male
Tamil
Benevolent, Kind hearted, Kind
ENDOTHELIN 3
ENDOTHELIN 3
ENDOTHELIN 3
ENDOTHELIN 3
ENDOTHELIN 3
n.
Same as Velum, 3.
n.
See Veil, n., 3 (b).
n.
A Russian liquid measure, equal to 3.249 gallons of U. S. standard measure, or 2.706 imperial gallons.
v. t.
A woman put out of the protection of the law. See Waive, v. t., 3 (b), and the Note.
n.
One of the primary planets. It is about 1,800,000,000 miles from the sun, about 36,000 miles in diameter, and its period of revolution round the sun is nearly 84 of our years.
a.
Like endothelium.
n.
A Spanish measure of length equal to about one yard. The vara now in use equals 33.385 inches.
pl.
of Endothelium
n.
The monitor. See Monitor, 3.
a.
Not divisible by two without a remainder; odd; -- said of numbers; as, 3, 7, and 11 are uneven numbers.
n.
The superficial layer of cells lining the alimentary canal and all its appendages, all glands and their ducts, blood vessels and lymphatics, serous cavities, etc. It often includes the epidermis (i. e., keratin-producing epithelial cells), and it is sometimes restricted to the alimentary canal, the glands and their appendages, -- the term endothelium being applied to the lining membrane of the blood vessels, lymphatics, and serous cavities.
n.
The thin epithelium lining the blood vessels, lymphatics, and serous cavities. See Epithelium.
n.
Same as Voucher, 3 (b).
n.
A Russian measure of length containing 3,500 English feet.
a.
A nobleman of the fourth rank, next in order below an earl and next above a baron; also, his degree or title of nobility. See Peer, n., 3.
a.
Of, or relating to, endothelium.
n.
See 2d Vail, 3.
a.
Not differentiated; specifically (Biol.), homogenous, or nearly so; -- said especially of young or embryonic tissues which have not yet undergone differentiation (see Differentiation, 3), that is, which show no visible separation into their different structural parts.
n.
Same as Unguis, 3.
n.
A genus of very large lizards native of Asia and Africa. It includes the monitors. See Monitor, 3.