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Protein-coding gene in the species Homo sapiens
Endothelin 2 (ET-2) is a protein encoded by the EDN2 gene in humans. It was first discovered in 1988 by Yanagisawa and team and belongs to a family of
Endothelin_2
Vasoconstricting peptide family
genes for endothelin-1 (ET-1), endothelin-2 (ET-2), and endothelin-3 (ET-3) are located on chromosomes 6, 1, and 20, respectively. Endothelin functions
Endothelin
Vasoconstricting peptide
Endothelin 1 (ET-1), also known as preproendothelin-1 (PPET1), is the most potent vasoconstrictor produced by the human body. It is a peptide produced
Endothelin_1
Drug that blocks endothelin receptors
An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors. Three main kinds of ERAs exist: Dual ET Receptor Antagonists, which
Endothelin receptor antagonist
Endothelin_receptor_antagonist
Protein-coding gene in the species Homo sapiens
Endothelin-3 is a protein that in humans is encoded by the EDN3 gene. The protein encoded by this gene is a member of the endothelin family. Endothelins
Endothelin_3
Chemical compound
the treatment of pulmonary hypertension. It is an endothelin receptor antagonist. The peptide endothelin constricts muscles in blood vessels, increasing
Ambrisentan
Chemical compound
both endothelin A and endothelin B receptors. Aprocitentan was approved for medical use in the United States in March 2024. It is the first endothelin receptor
Aprocitentan
Chemical compound
the brand name Tyvalzi) is a synthetic analog of endothelin-1 that works as a selective endothelin-B receptor agonist. In May 2023, it was approved in
Sovateltide
Breed of chicken from Indonesia
their 20th chromosome involving the endothelin 3 gene (EDN3). The roosters weigh 2–2.5 kg (4.4–5.5 lb) and the hens 1.5–2 kg (3.3–4.4 lb). The hens lay tinted
Ayam_Cemani
Chemical compound
Macitentan, sold under the brand name Opsumit, is an endothelin receptor antagonist developed by Actelion and approved for the treatment of pulmonary arterial
Macitentan
Chemical compound
brand name Pivlaz) is a drug belonging to the class of endothelin receptor antagonists. The endothelin 1 receptor is one of the strongest known vasoconstrictors
Clazosentan
Group of autoimmune diseases resulting in abnormal growth of connective tissue
decrease collagen degradation and increase extracellular matrix production. Endothelin signalling is implicated in the pathophysiology of fibrosis. Vitamin D
Scleroderma
Medication
Bosentan, sold under the brand name Tracleer among others, is a dual endothelin receptor antagonist medication used in the treatment of pulmonary artery
Bosentan
Protein toxin family
derivations of previously mentioned ones. The main differences in the family of endothelin and sarafotoxins appear at N-terminal of peptides, as C-terminal in all
Sarafotoxin
Chemical compound
BQ-123 is a selective ETA endothelin receptor antagonist. As such, it is used as a biochemical tool in the study of endothelin receptor function. BQ-123
BQ-123
High blood pressure in the pulmonary arteries
vasodilation. Endothelin receptor antagonists cause vasodilation as well by blocking the action of the potent vasoconstrictor endothelin-1. Prostacyclins
Pulmonary arterial hypertension
Pulmonary_arterial_hypertension
G protein-coupled receptor
There are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation
Endothelin_receptor
Protein-coding gene in the species Homo sapiens
Endothelin receptor type B, (ET-B) is a protein that in humans is encoded by the EDNRB gene. Endothelin receptor type B is a G protein-coupled receptor
Endothelin_receptor_type_B
Breed of chicken
Carl-Johan (2016-02-16). "A Complex Genomic Rearrangement Involving the Endothelin 3 Locus Causes Dermal Hyperpigmentation in the Chicken". PLOS Genet. 7
Svarthöna
Chemical compound
experimental anti-cancer drug candidate in development by AstraZeneca. It is an endothelin receptor antagonist. Zibotentan was granted fast track status for the
Zibotentan
Increased blood pressure in lung arteries
activity) decreases. Endothelin-1 is a peptide (comprising 21 amino acids) that is produced in endothelial cells. It acts on the endothelin receptors ETA and
Pulmonary_hypertension
Chemical compound
of endothelin (ET) on the endothelin-A (ETA) receptor selectively (by a factor of 6000 compared with the ETB). It is a sulfonamide class endothelin receptor
Sitaxentan
Genetic disorder in horses
to Hirschsprung's disease in humans. A mutation in the middle of the endothelin receptor type B (EDNRB) gene causes lethal white syndrome when homozygous
Lethal_white_syndrome
Chemical compound
Tazi KA, Barriere E, Poirel O, et al. (December 2004). "Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic
Tezosentan
Human chromosome
alpha 2 DES: Desmin protein DIS3L2: DIS3 mitotic control homolog-like 2 ECEL1: Endothelin converting enzyme like 1 EPC2: Enhancer of polycomb homolog 2 EPB41L5:
Chromosome_2
Chemical compound
brand name Vanrafia, is a medication used to reduce proteinuria. It is an endothelin receptor antagonist. It is taken by mouth. Atrasentan was approved for
Atrasentan
Urocortin Antagonists: Astressin-B See here instead. Agonists: Endothelin 1 Endothelin 2 Endothelin 3 IRL-1620 Sarafotoxin Antagonists: A-192621 Ambrisentan
List of signaling peptide/protein receptor modulators
List_of_signaling_peptide/protein_receptor_modulators
Mammalian protein found in Homo sapiens
keratinocytes and endothelial cells. Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1), -2 (EDN2), and -3 (EDN3) to
Endothelin converting enzyme 1
Endothelin_converting_enzyme_1
Mammalian protein found in humans
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline)
Beta-2_adrenergic_receptor
Drugs blocking alpha-2 adrenergic receptors
Alpha-2 blockers (or α2 blockers) are a subset of the alpha blocker class of drugs and are antagonists to the α2 adrenergic receptor. They are mainly
Alpha-2_blocker
Physiological processes of hypertension
sympathetic drive in hypertension include reactive oxygen species and endothelin. Some studies have shown that hypertensive patients manifest greater vasoconstrictor
Pathophysiology of hypertension
Pathophysiology_of_hypertension
Medical condition
hormones; angiotensin II, endothelin-1 and the catecholamines (e.g. noradrenaline).[citation needed] Angiotensin-II and endothelin-1 are hormones that bind
Right_ventricular_hypertrophy
Cell surface receptors
hormone Sauvagine Urocortin Antagonists Astressin-B Agonists Endothelin 1 Endothelin 2 Endothelin 3 IRL-1620 Sarafotoxin Antagonists A-192621 Ambrisentan Aprocitentan
Signaling_peptide_receptor
Human blood group classification
transmembrane zinc-dependent endopeptidase which is responsible for cleaving endothelin-3. The KEL gene encodes a type II transmembrane glycoprotein that is the
Kell_antigen_system
Swiss biopharmaceutical company
treatment. Actelion scientists were among the first to work in the field of endothelin receptor antagonists. Actelion was initially financed with venture capital
Actelion
Protein family
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists
Alpha-2_adrenergic_receptor
276.249 – endothelins MeSH D12.644.276.249.225 – endothelin-1 MeSH D12.644.276.249.235 – endothelin-2 MeSH D12.644.276.249.245 – endothelin-3 MeSH D12
List_of_MeSH_codes_(D12.644)
Medical condition
D – sensorineural deafness. The syndrome is caused by mutation in the endothelin B receptor gene (EDNRB). In the beginning, medical officials defined ABCD
ABCD_syndrome
Protein-coding gene in the species Homo sapiens
Endothelin B receptor-like protein 2 is a protein that in humans is encoded by the GPR37L1 gene. GRCh38: Ensembl release 89: ENSG00000170075 – Ensembl
GPR37L1
Protein and coding gene in humans
within pharyngeal arch 1 through ectoderm-mesenchyme signaling via the endothelin-Dlx5/6 pathway. In dogs, a variant on the Rspo2 gene is associated moustache
R-spondin_2
Genetic condition involving hearing loss and depigmentation
American Paint Horses by phenotype, brainstem auditory-evoked responses, and endothelin receptor B genotype". Journal of the American Veterinary Medical Association
Waardenburg_syndrome
Protein-coding gene in the species Homo sapiens
Endothelin-converting enzyme-like 1 is a protein that in humans is encoded by the ECEL1 gene. This gene encodes a member of the neutral endopeptidase (NEP)-related
ECEL1
Narrowing of blood vessels due to the constriction of smooth muscle cells
vasoconstriction, including the release of vasoconstrictor substances such as endothelin and angiotensin II, both of which play crucial roles in the modulation
Vasoconstriction
Protein-coding gene in the species Homo sapiens
Protease activated receptor 2 (PAR2) also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11) is
Protease-activated_receptor_2
Protein-coding gene in the species Homo sapiens
Hydroxycarboxylic acid receptor 2 (HCA2), also known as GPR109A and niacin receptor 1 (NIACR1), is a protein which in humans is encoded (its formation
Hydroxycarboxylic acid receptor 2
Hydroxycarboxylic_acid_receptor_2
Chemical compound
BQ-788 is a selective ETB antagonist. Endothelin Okada, M; Nishikibe, M (Winter 2002). "BQ-788, a selective endothelin ET(B) receptor antagonist". Cardiovascular
BQ-788
Bleeding into the brain's subarachnoid space
and endothelin-1 in delayed cerebral vasospasm produced by aneurysmal subarachnoid hemorrhage". Nature Clinical Practice Cardiovascular Medicine. 1 (2):
Subarachnoid_hemorrhage
inhibitor) Azabon Apricoxib (COX-2 inhibitor) Celecoxib (COX-2 inhibitor) Parecoxib (COX-2 inhibitor) Bosentan (endothelin receptor antagonist) Diazoxide
List_of_sulfonamides
Protein-coding gene in the species Homo sapiens
Parathyroid hormone 2 receptor is a protein that in humans is encoded by the PTH2R gene. The protein encoded by this gene is a member of the G protein-coupled
Parathyroid hormone 2 receptor
Parathyroid_hormone_2_receptor
Measurable indicators of diabetes
therapeutic targets for patients with prediabetes or Type 2 diabetes mellitus. Oxytocin (OXT) Omentin Endothelin-1 Nesfatin-1 Irisin Betatrophin Hepatocyte growth
Biomarkers_of_diabetes
Chemical compound
Darusentan (LU-135252; HMR-4005) is an endothelin receptor antagonist. Gilead Colorado, a subsidiary of Gilead Sciences, under license from Abbott Laboratories
Darusentan
Protein-coding gene in the species Homo sapiens
Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2 (HcrtR2), is a protein that in humans is encoded by the HCRTR2 gene. It
Hypocretin (orexin) receptor 2
Hypocretin_(orexin)_receptor_2
Substance that binds to a receptor to change its response to stimuli
a receptor. One is its capability or incapability to activate a receptor (2 possibilities). The other two are agonist affinity and efficacy. They may
Allosteric_modulator
Medical condition in which spasm of arteries causes episodes of reduced blood flow
ischemia and pulmonary hypertension in Raynaud's phenomenon, and the endothelin receptor antagonist bosentan is used to manage severe pulmonary hypertension
Raynaud_syndrome
Medication
nephropathy and focal segmental glomerulosclerosis. Sparsentan is an endothelin and angiotensin II receptor antagonist. It is taken by mouth. The most
Sparsentan
Medical condition
4A is an extremely rare congenital disorder caused by a mutation in an endothelin receptor gene. It results in common Waardenburg syndrome symptoms such
Waardenburg_syndrome_type_4A
Class of drugs
receptors. The alpha-adrenergic receptor has two subclasses, α1 and α2. Alpha 2 receptors are associated with sympatholytic properties, while alpha 1 receptors
Alpha-adrenergic_agonist
Protein found in humans
Brain-specific angiogenesis inhibitor 2 is a protein that in humans is encoded by the BAI2 gene. It is a member of the adhesion-GPCR family of receptors
Brain-specific angiogenesis inhibitor 2
Brain-specific_angiogenesis_inhibitor_2
Medical condition
prostacyclin and thromboxane (from Kupffer cells) or nitric oxide (NO) and endothelin-1 (ET-1). ET-1 is the most potent vasoconstrictor under investigation
Portopulmonary_hypertension
Autoimmune diseases of the skin
dysregulation of the renin–angiotensin system, elevated blood levels of endothelin 1, and increased oxidative stress. The number of new cases of the heart
Psoriasis
Protein found in humans
Corticotropin-releasing hormone receptor 2 (CRHR2) is a protein, also known by the IUPHAR-recommended name CRF2, that is encoded by the CRHR2 gene and
Corticotropin-releasing hormone receptor 2
Corticotropin-releasing_hormone_receptor_2
Impaired function of the inner lining of blood/lymph vessels
stress by releasing mediators, such as nitric oxide, prostacyclin and endothelin, and by controlling local angiotensin-II activity. Dysfunctional endothelium
Endothelial_dysfunction
Disorder of depression and mood episodes
signaling, cardiac hypertrophy signaling, Wnt signaling, Notch signaling, and endothelin 1 signaling. Of the 16 genes identified in these pathways, three were
Bipolar_disorder
Inner layer of blood vessel
been shown to release local chemicals called endothelins which are powerful vasoconstrictors. Endothelins help to regulate capillary exchange and alter
Tunica_intima
Chemical compound
"Development of a Scalable Process for CI-1034, an Endothelin Antagonist". Organic Process Research & Development. 8 (2): 201–212. doi:10.1021/op034104g. Chinchilla
Bis(triphenylphosphine)palladium chloride
Bis(triphenylphosphine)palladium_chloride
Color pattern in horses
DNA test developed, is produced by the Ile118Lys mutation on the equine Endothelin receptor type B gene and when homozygous produces lethal white syndrome
Sabino_horse
Ballooning or rupturing of a blood vessel in the brain
perlecan, elastin, collagen type 1 A2, endothelial nitric oxide synthase, endothelin receptor A and cyclin dependent kinase inhibitor. Recently, several genetic
Intracranial_aneurysm
Protein-coding gene in the species Homo sapiens
Endothelin receptor type A, also known as ETA, is a human G protein-coupled receptor. Endothelin receptor type A has been shown to interact with HDAC7A
Endothelin_A_receptor
Mammalian protein found in Homo sapiens
The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It
Cannabinoid_receptor_2
Chemical compound
Mechanisms for Contraction to Angiotensin II and Endothelin-1". Journal of the American Society of Hypertension. 3 (2): 84–95. doi:10.1016/j.jash.2008.09.002.
Fimasartan
Protein-coding gene in the species Homo sapiens
Galanin receptor 2, (GAL2) is a G-protein coupled receptor encoded by the GALR2 gene. Galanin is an important neuromodulator present in the brain, gastrointestinal
Galanin_receptor_2
Protein-coding gene in the species Homo sapiens
Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. AVPR2
Vasopressin_receptor_2
Medical condition of the cerebral arteries
vasodilators (like nitric oxide and prostacyclin) and vasoconstrictors (like endothelin). In vasospasm, endothelial damage disrupts this balance, reducing vasodilator
Cerebral_vasospasm
Chemical compound
K; Tigyi, G J; Leffler, C W (1997). "Role of lysophosphatidic acid in endothelin-1-and hematoma-induced alteration of cerebral microcirculation". American
Lysophosphatidic_acid
G protein-coupled receptor
antidepressant-like activities of MCL0129 (1-[(S)-2-(4-fluorophenyl)-2-(4-isopropylpiperadin-1-yl)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine), a
Melanocortin_receptor
Mammalian protein found in humans
Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene. mGluR2 is a G protein-coupled receptor (GPCR) that
Metabotropic glutamate receptor 2
Metabotropic_glutamate_receptor_2
Chemical compound
enzyme thermolysin, of the membrane metallo-endopeptidase, and of the endothelin converting enzyme. Chemically, phosphoramidon differs from its closely
Phosphoramidon
Protein-coding gene in the species Homo sapiens
Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. The SSTR2 gene is located on chromosome 17 on the long arm in position
Somatostatin_receptor_2
Widening of blood vessels
as endogenous and exogenous. The vasodilating action of activation of beta-2 receptors (such as by adrenaline) appears to be endothelium-independent. As
Vasodilation
Category of drug
Dihydroergolines (e.g., ergoloid (dihydroergotoxine)) Etazepine Etifoxine 2-Substituted phenols (e.g., thymol, eugenol) Imidazoles (e.g., etomidate) Kavalactones
GABA_receptor_agonist
Medication
treatment of pulmonary arterial hypertension. It contains macitentan, an endothelin receptor antagonist (ERA); and tadalafil, a phosphodiesterase 5 (PDE5)
Macitentan/tadalafil
G-protein-coupled receptor
(HCRTR1, HCRTR2). Both orexin receptors exhibit a similar pharmacology – the 2 orexin peptides, orexin-A and orexin-B, bind to both receptors and, in each
Orexin_receptor
Mammalian protein
2003-1695. PMID 15090463. Casey ML, MacDonald PC (October 1996). "The endothelin-parathyroid hormone-related protein vasoactive peptide system in human
Parathyroid hormone-related protein
Parathyroid_hormone-related_protein
Endocrine gland in the brain of most vertebrates
2004). "Cellular distribution of the endothelin system in the human brain". Journal of Chemical Neuroanatomy. 27 (2): 87–98. doi:10.1016/j.jchemneu.2003
Pineal_gland
Species of fungus
Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes". Scientific Reports
Psilocybe_cubensis
Compounds that bind to and activate adrenergic beta-2 receptors
ISBN 978-3-319-52173-2. PMC 5480238. PMID 27878470. Lulich KM, Goldie RG, Ryan G, Paterson JW (July 1986). "Adverse reactions to beta 2-agonist bronchodilators"
Beta2-adrenergic_agonist
Disease of the kidney
IgA nephropathy. It is a dual endothelin angiotensin receptor antagonist that uniquely combines angiotensin and endothelin inhibition without immunosuppression
IgA_nephropathy
Cardiac hormone which increases renal sodium excretion
concentration is not the direct stimulus for increased ANP secretion Endothelin, a potent vasoconstrictor Recently, it was discovered that ANP also can
Atrial_natriuretic_peptide
Subclass of purinergic P2 receptors
). Cleveland, OH: Elsevier Inc. pp. 375–378. doi:10.1016/B978-0-12-378630-2.00350-9. ISBN 978-0-12-378631-9. Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L
P2Y_receptor
Organ that connects the fetus to the uterine wall
intermingling of fetal and maternal blood occurs ("placental barrier"). Endothelin and prostanoids cause vasoconstriction in placental arteries, while nitric
Placenta
Changes in the physiology of the heart
such as Angiotensin II, Transforming growth factor beta (TGF-beta), and Endothelin 1 are known to trigger synthesis and degradation of collagen fibres in
Ventricular_remodeling
Involuntary non-striated muscle
invaginations in the sarcoplasm contain a host of receptors (prostacyclin, endothelin, serotonin, muscarinic receptors, adrenergic receptors), second messenger
Smooth_muscle
Drug that makes neurotransmitter transporters more active
Adenosine reuptake inhibitor (AdoRI) Angiotensin II receptor antagonist Endothelin receptor antagonist NK1 receptor antagonist Vasopressin receptor antagonist
Reuptake_enhancer
Genetic color in horses
Bellone R; Bailey E (2008). Barsh, Gregory S. (ed.). "Missense Mutation in Exon 2 of SLC36A1 Responsible for Champagne Dilution in Horses". PLOS Genetics. 4
Palomino
Relationship between biological organs
prolactin, oxytocin, and prostaglandins. Luteolysis involves factors such as endothelin-1 and TNFα, which inhibit steroidogenesis and induce apoptosis. Estrogen
Hypothalamic–pituitary–gonadal axis
Hypothalamic–pituitary–gonadal_axis
Chemical compound
PMID 12297490. Maguire JJ, Davenport AP (Nov 2002). "Is urotensin-II the new endothelin?". British Journal of Pharmacology. 137 (5): 579–88. doi:10.1038/sj.bjp
Urotensin-II
Drugs that block the action of histamine
carbon, nitrogen, or CO Spacer between the central X and the amine, usually 2–3 carbons in length, linear, ring, branched, saturated, or unsaturated Amine
H1_antagonist
Protein-coding gene in the species Homo sapiens
which is inhibited by SP1. BMPER is inhibited by endothelin-1, which may be mediated by endothelin inhibition of KLF15. GRCh38: Ensembl release 89: ENSG00000164619
BMP binding endothelial regulator
BMP_binding_endothelial_regulator
Protein-coding gene in the species Homo sapiens
Neuropeptide FF receptor 2, also known as NPFF2 and formerly as GPR74, is a human protein encoded by the NPFFR2 gene. Neuropeptide FF receptor GRCh38:
Neuropeptide_FF_receptor_2
Protein-coding gene in the species Homo sapiens
Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2
TAAR2
ENDOTHELIN 2
ENDOTHELIN 2
Surname or Lastname
English
English : patronymic from a variant spelling of Mayer 1.English : variant of Myers.Spanish : variant of Mier 2.Dutch : variant of Mier 3.Dutch (van der Miers) : variant of Meers 2.
Surname or Lastname
English
English : variant of Mixon 2.
Surname or Lastname
English
English : variant of Maul 2.
Surname or Lastname
English
English : variant spelling of Miner.German : nickname, meaning ‘small(er)’, from Latin minor ‘less’, ‘smaller’.French : nickname meaning ‘younger’, from the same word as in 2.
Surname or Lastname
Americanized spelling of German Beiss(e), a variant of Beitz 2.English
Americanized spelling of German Beiss(e), a variant of Beitz 2.English : perhaps a variant of Biss. Compare Beese, Bise, Buys, Byce.Hungarian : nickname for someone with a limp or a peculiar gait, from bice ‘limp’.
Surname or Lastname
English
English : habitational name from places called Merton in London, Devon, Norfolk, and Oxfordshire, named in Old English with mere ‘lake’, ‘pool’ + tūn ‘enclosure’, ‘settlement’. Compare Marton, Martin 2.
Surname or Lastname
English
English : patronymic meaning ‘son of the mayor’ (see Mayer 1).Jewish (Ashkenazic) : patronymic from the personal Meyer (see Meyer 2).American form of German Meyer, with excrescent -s.Irish : variant of Meyer 3.
Surname or Lastname
English
English : patronymic from Mayer 1.German : patronymic from Mayer 2.Dutch : variant of Meyer 1 and 3.
Surname or Lastname
English
English : habitational name from Melhuish in Devon, so called from Old English mǣl(e) ‘brightly colored’, ‘flowery’ + hīwisc ‘hide’ (a measurement of land).Scottish : variant of Mellis 2.
Surname or Lastname
English (Lancashire)
English (Lancashire) : variant spelling of Mayer 1.Spanish and Jewish (Sephardic) : nickname for an older man or a distinguishing epithet for the elder of two bearers of the same personal name, from Spanish mayor ‘older’ (Latin maior (natus), literally ‘greater (by birth)’).Spanish and Jewish (Sephardic) : occupational or status name, from major ‘governor’, ‘chief’.Catalan : variant spelling of Major.Jewish (Ashkenazic) : variant of Meyer 2.
Surname or Lastname
Americanized spelling of Jewish Leykin (from Belarus), a metronymic from Leyke, a pet form of the Yiddish female personal name Leye, from the Hebrew female personal name Lea, from which English Leah is derived (see Genesis 29
Americanized spelling of Jewish Leykin (from Belarus), a metronymic from Leyke, a pet form of the Yiddish female personal name Leye, from the Hebrew female personal name Lea, from which English Leah is derived (see Genesis 29 : 16) + the Slavic possessive suffix -in.English : from a medieval personal name, a diminutive of Lawrence. Compare Law 1 and Larkin.
Surname or Lastname
English
English : variant spelling of Mellis 1.German : variant of Melius.Dutch ((van) Melis) : variant of Millis 2.Czech and Slovak (Meliš), and Hungarian : from a short form of the Biblical personal name Melichar (see Melchior).Greek : from the personal name Melis, a pet form of Meletios or Meliton (names of various early saints and martyrs). The personal names are derived from either meli ‘honey’ or meletan ‘care for’, ‘study’.Italian (Sardinia and southern Italy) : habitational name from a place so named in Sardinia.Lithuanian : nickname from melis ‘blue’.Latvian : unflattering nickname from melis ‘liar’.Latvian : variant of Mellis.
Surname or Lastname
English
English : variant of or patronymic from Merritt 2.
Surname or Lastname
North German variant of Laas 2.Jewish (Ashkenazic)
North German variant of Laas 2.Jewish (Ashkenazic) : unexplained.English : nickname from Middle English lesse, lasse ‘smaller’ (from Old English lǣssa ‘less’), perhaps also used in the sense ‘younger’.
Surname or Lastname
English and Scottish
English and Scottish : variant of Mill 1.English : either a metronymic form of Mill 2, or a variant of Miles.Irish : in Ulster this is the English name, but elsewhere in Ireland it may be a translation of a Gaelic topographic byname, an Mhuilinn ‘of the mill’.
Surname or Lastname
Variant of Nicolai 2.English
Variant of Nicolai 2.English : variant of Nicholas.
Surname or Lastname
English
English : topographic name for someone who lived by a meadow, from Mead 1 + the suffix -er, denoting an inhabitant.English : occupational name for a brewer or seller of mead, Middle English med(i)er (see Mead 2).
Surname or Lastname
Americanized spelling of Swiss German Bürki, or an altered spelling of Berke (see Berke 2).Possibly an Americanized spelling of Hungarian Berki, a habitational name from a village called Berki, in Pest county, or a topographic name from berek ‘marsh wi
Americanized spelling of Swiss German Bürki, or an altered spelling of Berke (see Berke 2).Possibly an Americanized spelling of Hungarian Berki, a habitational name from a village called Berki, in Pest county, or a topographic name from berek ‘marsh with groves’.English : unexplained.
Surname or Lastname
French
French : from a short form of the personal name Amaury (see Emery).Southern French (Occitan) : habitational name from Maury, in Basses Pyrénées.English : probably a variant of Morey 2.
Surname or Lastname
English
English : status name for a mayor, Middle English, Old French mair(e) (from Latin maior ‘greater’, ‘superior’; compare Mayor). In France the title denoted various minor local officials, and the same is true of Scotland (see Mair 1). In England, however, the term was normally restricted to the chief officer of a borough, and the surname may have been given not only to a citizen of some standing who had held this office, but also as a nickname to a pompous or officious person.German and Dutch : variant of Meyer 1.Jewish (Ashkenazic) : variant of Meyer 2.
ENDOTHELIN 2
ENDOTHELIN 2
Boy/Male
Hindu
Inside viewer, Spilt second
Girl/Female
Tamil
Mehanaz | மேஹாநாஜ
Boy/Male
Welsh
From York.
Boy/Male
Tamil
Longing
Boy/Male
Tamil
Shubh Ansh
Boy/Male
Tamil
Krishnasai | கà¯à®°à¯€à®·à¯à®¨à®¾à®¸à®¾à®ˆ
Dark complexioned, Lord Krishna, Name of a river
Boy/Male
Bengali, Hindu, Indian
Lord Shiva
Male
African
we shall see.
Boy/Male
Greek
Protect the king. The Greek form of the Old Testament Bel-shazzar, referring to the Babylonian...
Boy/Male
Hindu
King of lanka, Ravana is a character in Hindu history, Who is the primary antagonist of the Hindu epic ramayana
ENDOTHELIN 2
ENDOTHELIN 2
ENDOTHELIN 2
ENDOTHELIN 2
ENDOTHELIN 2
n.
A game in word making. See Logomachy, 2.
n.
One of the planets, the second in order from the sun, its orbit lying between that of Mercury and that of the Earth, at a mean distance from the sun of about 67,000,000 miles. Its diameter is 7,700 miles, and its sidereal period 224.7 days. As the morning star, it was called by the ancients Lucifer; as the evening star, Hesperus.
n.
One of the vessels which carry blood, either venous or arterial, to the heart. See Artery, 2.
n.
A sign of the zodiac which the sun enters about the 21st of August, marked thus [/] in almanacs.
n.
A compensation given to a hired person for services; price paid for labor; recompense; hire. See Wage, n., 2.
pl.
of Endothelium
n.
The superficial layer of cells lining the alimentary canal and all its appendages, all glands and their ducts, blood vessels and lymphatics, serous cavities, etc. It often includes the epidermis (i. e., keratin-producing epithelial cells), and it is sometimes restricted to the alimentary canal, the glands and their appendages, -- the term endothelium being applied to the lining membrane of the blood vessels, lymphatics, and serous cavities.
n.
See Viol, 2.
a.
The sixth month of the calendar adopted by the first French republic. It began February 19, and ended March 20. See Vend/miaire.
n.
A book composed of sheets each of which is folded into twenty-four leaves; hence, indicating more or less definitely a size of book so made; -- usually written 24mo, or 24¡.
a.
Of, or relating to, endothelium.
a.
Of no legal force or effect, incapable of confirmation or ratification; null. Cf. Voidable, 2.
a.
Consisting of, or characterized by, voice, or tone produced in the larynx, which may be modified, either by resonance, as in the case of the vowels, or by obstructive action, as in certain consonants, such as v, l, etc., or by both, as in the nasals m, n, ng; sonant; intonated; voiced. See Voice, and Vowel, also Guide to Pronunciation, // 199-202.
n.
The first month of the French republican calendar, dating from September 22, 1792.
n.
The thin epithelium lining the blood vessels, lymphatics, and serous cavities. See Epithelium.
a.
Like endothelium.
n.
See Vinaigrette, n., 2.
a.
Somewhat viscous. Cf. Mobile, a., 2.