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CDK12

  • CDK12

    • Protein kinase gene

    CDK12 cyclin-dependent kinase 12 is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein

    CDK12

    CDK12

    CDK12

  • Katherine Jones (academic)

    • Biochemist

    studied the CDK12 gene, which is mutated in 3 - 5% of prostate, ovarian and breast cancers. The majority of cancers that contain a mutated CDK12 gene are

    Katherine Jones (academic)

    Katherine Jones (academic)

    Katherine_Jones_(academic)

  • Molecular glue

    • Class of chemical compounds

    RBM39/RBM23. [see also indisulam, tasisulam] CR8 [CDK12-DDB1] Links CDK12 to CRL4-DDB1 ligase, triggering CDK12-associated cyclin K degradation. PF-07208254

    Molecular glue

    Molecular glue

    Molecular_glue

  • Ovarian cancer

    • Cancer originating in or on the ovary

    common gene mutations in ovarian cancer occur in NF1, BRCA1, BRCA2, and CDK12. Type I ovarian cancers, which tend to be less aggressive, tend to have

    Ovarian cancer

    Ovarian cancer

    Ovarian_cancer

  • Serine/threonine-specific protein kinase

    • Class of protein kinase enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • Titin

    • Largest known protein in human muscles

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Titin

    Titin

    Titin

  • Ca2+/calmodulin-dependent protein kinase II

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • Casein kinase 1, alpha 1

    • Enzyme found in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Casein kinase 1, alpha 1

    Casein kinase 1, alpha 1

    Casein_kinase_1,_alpha_1

  • ATM serine/threonine kinase

    • Mammalian protein found in Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    ATM serine/threonine kinase

    ATM serine/threonine kinase

    ATM_serine/threonine_kinase

  • GAK (protein)

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • Talazoparib

    • Chemical compound

    with a CYP17 inhibitor or docetaxel. HRR genes (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) were assessed prospectively

    Talazoparib

    Talazoparib

    Talazoparib

  • Mitogen-activated protein kinase kinase

    • Kinase enzyme

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Mitogen-activated protein kinase kinase

    Mitogen-activated_protein_kinase_kinase

  • Mitogen-activated protein kinase

    • P38 mitogen-activated protein kinases

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • G protein-coupled receptor kinase

    • Family of protein kinases

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    G protein-coupled receptor kinase

    G protein-coupled receptor kinase

    G_protein-coupled_receptor_kinase

  • Cyclin-dependent kinase 6

    • Protein found in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Cyclin-dependent kinase 6

    Cyclin-dependent kinase 6

    Cyclin-dependent_kinase_6

  • AMP-activated protein kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • Cyclin-dependent kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • SNRK

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    SNRK

    SNRK

    SNRK

  • TRIB3

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    TRIB3

    TRIB3

    TRIB3

  • Rhodopsin kinase

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Rhodopsin kinase

    Rhodopsin_kinase

  • Casein kinase 2

    • Protein

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Casein kinase 2

    Casein_kinase_2

  • (tyrosine 3-monooxygenase) kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    (tyrosine 3-monooxygenase) kinase

    (tyrosine_3-monooxygenase)_kinase

  • TRIB1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    TRIB1

    TRIB1

    TRIB1

  • PHKG2

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PHKG2

    PHKG2

    PHKG2

  • Wee1-like protein kinase

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Wee1-like protein kinase

    Wee1-like protein kinase

    Wee1-like_protein_kinase

  • RPS6KA5

    • Enzyme

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    RPS6KA5

    RPS6KA5

    RPS6KA5

  • Extracellular signal-regulated kinases

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • TGF beta receptor

    • Protein family

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    TGF beta receptor

    TGF_beta_receptor

  • MAP3K8

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MAP3K8

    MAP3K8

    MAP3K8

  • IDH3G

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    IDH3G

    IDH3G

    IDH3G

  • PHKG1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PHKG1

    PHKG1

    PHKG1

  • MAPK13

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MAPK13

    MAPK13

    MAPK13

  • PLK3

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PLK3

    PLK3

    PLK3

  • Protein kinase B

    • Set of three serine threonine-specific protein kinases

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • PKN3 (gene)

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PKN3 (gene)

    PKN3 (gene)

    PKN3_(gene)

  • C-Jun N-terminal kinases

    • Chemical compounds

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • Protein kinase C

    • Family of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase C

    Protein_kinase_C

  • MYLK

    • Gene of the immunoglobulin superfamily

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MYLK

    MYLK

    MYLK

  • EIF-2 kinase

    • Protein serine/threonine kinase that is induced by interferon

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    EIF-2 kinase

    EIF-2 kinase

    EIF-2_kinase

  • MTORC1

    • Protein complex

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MTORC1

    MTORC1

    MTORC1

  • P38 mitogen-activated protein kinases

    • Protein family

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • MAP kinase kinase kinase kinase

    • Family of proteins

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • IkappaB kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    IkappaB kinase

    IkappaB_kinase

  • Phototropin

    • Class of photoreceptor proteins in plants

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Phototropin

    Phototropin

  • MTOR

    • Mammalian protein found in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MTOR

    MTOR

    MTOR

  • P70-S6 Kinase 1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • Cyclin-dependent kinase complex

    • phase p16INK4A, p19INK4D, and P18INK4C-cyclin K Cdk8 Cyclin C --- --- Cdk9 Cyclin T --- Tat, AFF4, and TAR Cdk12 Cyclin K --- --- Cdk13 Cyclin K --- ---

    Cyclin-dependent kinase complex

    Cyclin-dependent kinase complex

    Cyclin-dependent_kinase_complex

  • Protein kinase A

    • Family of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • The Cancer Genome Atlas

    • Project to catalogue genetic mutations responsible for cancer

    found in a handful of other genes, including NF1, BRCA1, BRCA2, RB1 and CDK12. TCGA researchers were also able to identify gene expression patterns that

    The Cancer Genome Atlas

    The_Cancer_Genome_Atlas

  • BRAF (gene)

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • Aurora inhibitor

    • Putative drug class for treating cancer

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • MTOR inhibitors

    • Class of pharmaceutical drugs

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • NLK

    • Mammalian protein found in Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    NLK

    NLK

    NLK

  • Protein kinase R

    • Human protein and coding gene

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • Cyclin-dependent kinase 7

    • Protein-coding gene in the species Homo sapiens

    forming a bond at C312, which is unique to CDK7 within the CDK family. CDK12 and CDK13 could also be inhibited using THZ1 (but at higher concentrations)

    Cyclin-dependent kinase 7

    Cyclin-dependent kinase 7

    Cyclin-dependent_kinase_7

  • Protein kinase domain

    • Protein domain

    CDC42BPA ; CDC42BPB ; CDC42BPG ; CDC7 ; CDK1 ; CDK10 ; CDK11A ; CDK11B ; CDK12 ; CDK13 ; CDK14 ; CDK15 ; CDK16 ; CDK17 ; CDK18 ; CDK19 ; CDK2 ; CDK20 ;

    Protein kinase domain

    Protein kinase domain

    Protein_kinase_domain

  • CAMK

    • Enzyme type

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    CAMK

    CAMK

  • VRK2

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    VRK2

    VRK2

    VRK2

  • PIK3R4

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PIK3R4

    PIK3R4

    PIK3R4

  • Phosphoinositide-dependent kinase-1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • BMPR1A

    • Bone morphogenetic protein receptor

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    BMPR1A

    BMPR1A

    BMPR1A

  • Cyclin K

    • Protein-coding gene in the species Homo sapiens

    has been shown to interact with multiple CDKs including CDK9 and latest CDK12 and CDK13. Roles include helping to phosphorylate C-terminal domains of

    Cyclin K

    Cyclin K

    Cyclin_K

  • RAF kinase

    • 7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    RAF kinase

    RAF kinase

    RAF_kinase

  • MTORC2

    • Protein complex

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MTORC2

    MTORC2

  • MAP kinase kinase kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • AKT1

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    AKT1

    AKT1

    AKT1

  • Myosin light-chain kinase

    • Class of kinase enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

  • GSK-3

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    GSK-3

    GSK-3

    GSK-3

  • Phosphatidylinositol 3-kinase-related kinase

    • Protein family

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • SMG1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    SMG1

    SMG1

    SMG1

  • PKMYT1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PKMYT1

    PKMYT1

    PKMYT1

  • Protein kinase C zeta type

    • Mammalian protein found in Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • MYLK2

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MYLK2

    MYLK2

    MYLK2

  • CHEK2

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    CHEK2

    CHEK2

    CHEK2

  • VRK1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    VRK1

    VRK1

    VRK1

  • Cyclin-dependent kinase 4

    • Human protein

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Cyclin-dependent kinase 4

    Cyclin-dependent kinase 4

    Cyclin-dependent_kinase_4

  • IKBKG

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    IKBKG

    IKBKG

    IKBKG

  • Ataxia telangiectasia and Rad3 related

    • Protein kinase that detects DNA damage and halts cell division

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Ataxia telangiectasia and Rad3 related

    Ataxia telangiectasia and Rad3 related

    Ataxia_telangiectasia_and_Rad3_related

  • CGMP-dependent protein kinase

    • Protein kinase

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    CGMP-dependent protein kinase

    CGMP-dependent protein kinase

    CGMP-dependent_protein_kinase

  • G protein-coupled receptor kinase 2

    • Enzyme

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    G protein-coupled receptor kinase 2

    G protein-coupled receptor kinase 2

    G_protein-coupled_receptor_kinase_2

  • Acetate kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Acetate kinase

    Acetate kinase

    Acetate_kinase

  • Phosphorylase kinase

    • Enzyme involved in glycogenolysis

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • SGK

    • Protein family

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    SGK

    SGK

  • DNA-PKcs

    • Protein found in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • Wee1

    • Nuclear protein

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Wee1

    Wee1

    Wee1

  • IRAK4

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    IRAK4

    IRAK4

    IRAK4

  • Protein kinase D1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase D1

    Protein kinase D1

    Protein_kinase_D1

  • 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    • Class of enzymes

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)_kinase

  • ACVR2B

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    ACVR2B

    ACVR2B

    ACVR2B

  • BMPR2

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    BMPR2

    BMPR2

    BMPR2

  • MAP2K1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    MAP2K1

    MAP2K1

    MAP2K1

  • ACVR1

    • Protein-coding gene

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    ACVR1

    ACVR1

    ACVR1

  • CHEK1

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    CHEK1

    CHEK1

    CHEK1

  • Bone morphogenetic protein receptor

    • Group of three receptors to bone morphogenetic proteins

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Bone morphogenetic protein receptor

    Bone_morphogenetic_protein_receptor

  • PLK1

    • Mammalian protein found in Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    PLK1

    PLK1

    PLK1

  • Rho-associated protein kinase

    • Protein family

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • CDKL5

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    CDKL5

    CDKL5

    CDKL5

  • IDH2

    • Protein-coding gene in humans

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    IDH2

    IDH2

    IDH2

  • DAPK1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    DAPK1

    DAPK1

    DAPK1

  • Protein kinase N1

    • Protein-coding gene in the species Homo sapiens

    7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6 CDK7 CDK8 CDK9 CDK10 CDK12 CDC2L5 PCTK1 PCTK2 PCTK3 PFTK1 CDC2L1 (RNA-polymerase)-subunit kinase (EC

    Protein kinase N1

    Protein kinase N1

    Protein_kinase_N1

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Online names & meanings

  • Marleigh

    • Girl/Female

    English

    Marleigh

    Marshy meadow. Also Woman from Magdala.

  • UZZIAH

    • Male

    English

    UZZIAH

    Variant spelling of English Uzzia, UZZIAH means "power of Jehovah."

  • Swarangana

    • Girl/Female

    Hindu

    Swarangana

  • Sanoj

    • Boy/Male

    Hindu

    Sanoj

    Immortal

  • Saanghvi

    • Girl/Female

    Gujarati, Hindu, Indian, Sanskrit

    Saanghvi

    Goddess Lakshmi

  • Inocenta

    • Girl/Female

    Spanish

    Inocenta

    Innocent.

  • Jemma

    • Girl/Female

    American, Australian, British, Christian, English, Italian, Latin

    Jemma

    Little Dove; Gem; Precious Stone; Jewel

  • VIDYA

    • Female

    Hindi/Indian

    VIDYA

    (विद्या) Hindi myth name borne by Saraswati, VIDYA means "knowledge.

  • Eiham

    • Boy/Male

    Indian

    Eiham

    Fantasy

  • Premanidhi

    • Girl/Female

    Hindu, Indian, Marathi

    Premanidhi

    The Treasure of Love

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CDK12

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