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Chemical compound
Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound
Carmustine
Drugs that are useful against cancer
of antineoplastic agents Altretamine Bendamustine Busulfan Carboquone Carmustine Chlorambucil Chlormethine Chlorozotocin Cyclophosphamide Dacarbazine Fotemustine
List of chemotherapeutic agents
List_of_chemotherapeutic_agents
Japanese pharmaceutical company
(palonosetron), Hexalen (altretamine) for ovarian cancer, and the Gliadel Wafer (carmustine) for brain tumors into the Eisai product portfolio. In 2009, Eisai received
Eisai_(company)
Family of chemical compounds
chemotherapy that have the ability to form ICLs are cisplatin, mitomycin C, carmustine, and psoralen. These kinds of lesions are effective at forcing the cell
Nitrogen_mustard
Low temperature dehydration process
intravenous "blood clot buster" used for treatment of ischemic stroke. Carmustine, a chemotherapy drug used for treatment of glioblastoma, brainstem glioma
Freeze_drying
Chemical compound
Examples include: Arabinopyranosyl-N-methyl-N-nitrosourea (Aranose) Carmustine (BCNU, BiCNU) Chlorozotocin Ethylnitrosourea (ENU) Fotemustine Lomustine
Nitrosourea
Type of immune system cancer
Topical and oral corticosteroids Bexarotene (Targretin) gel and capsules Carmustine (BCNU, a nitrosourea) Mechlorethamine (nitrogen mustard) Phototherapy
Cutaneous_T-cell_lymphoma
Pharmaceutical drugs
uracil mustard Melphalan Chlorambucil Ifosfamide Bendamustine Nitrosoureas Carmustine Lomustine Streptozocin Alkyl sulfonates Busulfan Platinum-based chemotherapeutic
Alkylating antineoplastic agent
Alkylating_antineoplastic_agent
Radiologic sign on radiographs and computed tomography scans
pneumonitis Drug toxicity (most common include cyclophosphamide, amiodarone, carmustine, methotrexate, and bleomycin) Hypersensitivity pneumonitis EVALI Radiation
Ground-glass_opacity
Diseases of the space or tissue between the alveoli of the lungs
Pulmonary Langerhans cell histiocytosis Silicosis Coal workers pneumoconiosis Carmustine-related pulmonary fibrosis Respiratory broncholitis associated with interstitial
Interstitial_lung_disease
Gene therapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Idecabtagene_vicleucel
Pharmaceutical drug classification
Mannosulfan L01AC01 Thiotepa L01AC02 Triaziquone L01AC03 Carboquone L01AD01 Carmustine L01AD02 Lomustine L01AD03 Semustine L01AD04 Streptozocin L01AD05 Fotemustine
ATC_code_L01
Chemotherapy regimen
CBV refers to Cytoxan (cyclophosphamide), BCNU (carmustine), and VP-16 (etoposide), three drugs in a chemotherapy regimen commonly given to lymphoma patients
CBV_(chemotherapy)
Medical technique
or loaded microbubbles without FUS. Another study found encapsulating carmustine in microbubbles led to a five-fold increase in the circulating half-life
Focused ultrasound for intracranial drug delivery
Focused_ultrasound_for_intracranial_drug_delivery
Chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Doxorubicin
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Enocitabine
Class of drugs used to treat malignant tumors
pneumonia and pulmonary fibrosis, with key drugs including bleomycin, carmustine, mitomycin C, methotrexate, and gefitinib. Long-term high-dose bleomycin
Antineoplastic
Chemical compound
(TBC) and thiotepa/carmustine (TT-BCNU) improve progression-free survival of PCNSL compared to traditional therapies carmustine/etoposide/cytarabine/melphalan
Thiotepa
Form of phototherapy
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Photodynamic_therapy
Cancerous tumor originating in the stomach lining
treatment have included: fluorouracil or its analog capecitabine, BCNU (carmustine), methyl-CCNU (semustine) and doxorubicin (Adriamycin), as well as mitomycin
Stomach_cancer
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Talazoparib
Nonsteroidal anti-inflammatory medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Celecoxib
Anti-breast cancer medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Abemaciclib
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Capecitabine
Common side effects in chemotherapy treatment
emetogenic agents and chemotherapy regimens include: ABVD AC BEP Cisplatin Carmustine (>250 mg/m2) CBV Cyclophosphamide (>1500 mg/m2) Dacarbazine Mechlorethamine
Chemotherapy-induced nausea and vomiting
Chemotherapy-induced_nausea_and_vomiting
Treatment of cancer using drugs that inhibit cell division or kill cells
ifosfamide and busulfan. Nitrosoureas include N-Nitroso-N-methylurea (NMU), carmustine (BCNU), lomustine (CCNU) and semustine (MeCCNU), fotemustine and streptozotocin
Chemotherapy
French multinational pharmaceutical and healthcare company
colorectal cancer. Fludara (Fludarabine), for leukemia. Gliadel Wafer (Carmustine), for cancer, now owned by Arbor Pharmaceuticals. Jevtana (Cabazitaxel)
Sanofi
American pharmaceutical company
(triamcinolone acetonide) Oncology Abecma (idecabtagene vicleucel) BiCNU (carmustine) Breyanzi (lisocabtagene maraleucel) CeeNU (lomustine) Droxia/Hydrea (hydroxycarbamide)
Bristol_Myers_Squibb
Chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Vinblastine
Chemical compound and pharmaceutical drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Cisplatin
Medication used as chemotherapy and to suppress the immune system
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Cyclophosphamide
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Epirubicin
Phenomenon in genetics
testicular and ovarian cancers. Chloro ethyl nitroso urea (CENU), specifically carmustine (BCNU), are crosslinking agents that are widely used in chemotherapy,
Crosslinking_of_DNA
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Chlorambucil
Concept in toxicology
with DNA replication and transcription by modifying DNA bases. Busulfan, Carmustine, Mechlorethamine Intercalating agents interfere with DNA replication and
Genotoxicity
Medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Tretinoin
U.S. health institute
Mitotane) (1970) Dacarbazine (DTIC) (1975) CCNU (Lomustine) (1976) BCNU (Carmustine) (1977) Cis-diamminedichloroplatinum (Cisplatin) (1978) Mitoxantrone (Novantrone)
National_Cancer_Institute
Chemotherapy and immunosuppressant medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Methotrexate
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Aminopterin
Chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Fluorouracil
Industrial chemical and medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Arsenic_trioxide
Highly aggressive brain tumor, mostly found in children
placed at the time of surgery and will release the chemotherapy agent carmustine slowly over time. This provides a much higher concentration of chemotherapy
Diffuse_midline_glioma
Drug type for epigenetic therapy
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Hypomethylating_agent
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Gemcitabine
Chemotherapy regimen for colorectal cancer treatment
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
FOLFIRI
Cell division inhibitor
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Mitotic_inhibitor
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Amsacrine
Chemical compound
compounds Tetramethylurea Noxytiolin Metformin Buformin Allantoic acid Carmustine Except where otherwise noted, data are given for materials in their standard
1,1,3,3-Tetramethylguanidine
Chemotherapeutic agents used to treat cancer
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Platinum-based_antineoplastic
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Vepdegestrant
Chemical compound (chemotherapy medication)
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Cytarabine
Gene therapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Lisocabtagene_maraleucel
Medication used for cancer
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Paclitaxel
Chemical compound
compounds Related compounds Noxytiolin 1,1,3,3-Tetramethylguanidine Metformin Carmustine Except where otherwise noted, data are given for materials in their standard
Allantoic_acid
Anti-cancer medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Vorasidenib
Medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Hydroxycarbamide
Chemical compound; chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Vincristine
Endogenous non-proteinogenic amino acid
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Aminolevulinic_acid
Cancer medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Temozolomide
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Floxuridine
Gene therapy medication used to treat multiple myeloma
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Ciltacabtagene_autoleucel
Pharmaceutical drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Tebentafusp
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Sotorasib
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Busulfan
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Mercaptopurine
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Bendamustine
Chemical compound
3-Dimethylurea 1,1,3,3-Tetramethylguanidine Metformin Allantoic acid Carmustine Except where otherwise noted, data are given for materials in their standard
Noxytiolin
Cancer drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Protein-bound_paclitaxel
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Mitomycin_C
Investigational oral small-molecule drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Pelabresib
Chemical that inhibits the use of a metabolite
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Antimetabolite
Medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Lifileucel
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Azacitidine
Drug for treatment of breast cancer
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Utidelone
Insertion of molecules between DNA
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Intercalation_(biochemistry)
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Taxane
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Belzutifan
Compounds that inhibit the activity of DNA topoisomerases
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Topoisomerase_inhibitor
Pharmaceutical drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Fuzuloparib
Medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Decitabine/cedazuridine
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Vatalanib
Chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Docetaxel
Cancer medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Irinotecan
Anticancer drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Olutasidenib
Chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Daunorubicin
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Hazardous_drug
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Dactolisib
Medication used to treat cancer
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Carboplatin
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Dordaviprone
Class of chemical compounds
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Indolocarbazole
Chemotherapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Etoposide
Experimental cancer drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Divarasib
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Rabacfosadine
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Stanford_V
Pharmaceutical drug
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Oxaliplatin
Cell based gene therapy
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Brexucabtagene_autoleucel
Chemical compound
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
4-Hydroxycyclophosphamide
Chemical compound
LD50 (median dose) 4 g kg−1 (oral, rat) Related compounds Related ureas Carmustine Related compounds Noxytiolin 1,1,3,3-Tetramethylguanidine Metformin Allantoic
1,3-Dimethylurea
Class of antibiotics
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Anthracycline
Gene therapy medication
Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine Lomustine (Semustine) Nimustine Ranimustine Streptozocin Alkyl
Nadofaragene_firadenovec
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