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CARDIOPROTECTION

  • Cardioprotection
  • Mechanisms that contribute to the preservation of the heart

    Cardioprotection includes all mechanisms and means that contribute to the preservation of the heart by reducing or even preventing myocardial damage. Cardioprotection

    Cardioprotection

    Cardioprotection

  • Ibuprofen
  • Nonsteroidal anti-inflammatory drug

    aspirin, potentially rendering aspirin less effective when used for cardioprotection and stroke prevention". Allowing sufficient time between doses of ibuprofen

    Ibuprofen

    Ibuprofen

    Ibuprofen

  • BW373U86
  • Opioid analgesic drug used in research

    (August 2001). "BW373U86, a δ Opioid Agonist, Partially Mediates Delayed Cardioprotection via a Free Radical Mechanism that is Independent of Opioid Receptor

    BW373U86

    BW373U86

    BW373U86

  • PRKCE
  • Protein-coding gene in the species Homo sapiens

    PKCε is clinically significant in that it is a central player in cardioprotection against ischemic injury and in the development of cardiac hypertrophy

    PRKCE

    PRKCE

    PRKCE

  • Xenon
  • Chemical element with atomic number 54 (Xe)

    original source, without environmental impact. Xenon induces robust cardioprotection and neuroprotection through a variety of mechanisms. Through its influence

    Xenon

    Xenon

    Xenon

  • Dexrazoxane
  • Chemical compound

    doxorubicin or > 540 mg/m2 epirubicin and general approval for use for cardioprotection. That showed a possibly higher rate of secondary malignancies and acute

    Dexrazoxane

    Dexrazoxane

    Dexrazoxane

  • Adenosine receptor
  • Class of four receptor proteins to the molecule adenosine

    PMC 2423946. PMID 18537674. Peart JN, Headrick JP (May 2007). "Adenosinergic cardioprotection: multiple receptors, multiple pathways". Pharmacology & Therapeutics

    Adenosine receptor

    Adenosine receptor

    Adenosine_receptor

  • Spermidine
  • Chemical compound

    U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A (2016). "Cardioprotection and lifespan extension by the natural polyamine spermidine". Nature

    Spermidine

    Spermidine

    Spermidine

  • Melatonin
  • Hormone released by the pineal gland

    red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection". Journal of Pineal Research

    Melatonin

    Melatonin

    Melatonin

  • Ciclosporin
  • Chemical compound

    NeuroVive's formulation of ciclosporin called Neurostat (also known by its cardioprotection brand name of Ciclomulsion). This formulation uses a lipid emulsion

    Ciclosporin

    Ciclosporin

    Ciclosporin

  • Tyrosol
  • Chemical compound

    Penumathsa SV, Paul D, Maulik N (2008). "Akt/FOXO3a/SIRT1-Mediated Cardioprotection by n-Tyrosol against Ischemic Stress in Rat in Vivo Model of Myocardial

    Tyrosol

    Tyrosol

    Tyrosol

  • VK2735
  • peptide-1/glucose-dependent insulinotropic polypeptide receptor co-agonists for cardioprotection, type 2 diabetes and obesity: a review of mechanisms and clinical data"

    VK2735

    VK2735

  • Reperfusion injury
  • Tissue damage after return of blood supply following ischemia or hypoxia

    PMID 14767591. S2CID 5733761. Heusch, Gerd (2015-02-13). "Molecular Basis of Cardioprotection Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning"

    Reperfusion injury

    Reperfusion injury

    Reperfusion_injury

  • Teprenone
  • Chemical compound

    S (September 2008). "Low-dose sevoflurane inhalation enhances late cardioprotection from the anti-ulcer drug geranylgeranylacetone". Anesth. Analg. 107

    Teprenone

    Teprenone

  • Aspartate transaminase
  • Enzyme involved in amino acid metabolism

    (September 2007). "The role of existing and novel cardiac biomarkers for cardioprotection". Current Opinion in Investigational Drugs. 8 (9): 711–717. PMID 17729182

    Aspartate transaminase

    Aspartate transaminase

    Aspartate_transaminase

  • Senescence
  • Deterioration of function with age

    O'Keefe JH, DiNicolantonio JJ, Lavie CJ (1 May 2018). "Coffee for Cardioprotection and Longevity". Progress in Cardiovascular Diseases. 61 (1): 38–42

    Senescence

    Senescence

    Senescence

  • CLIC4
  • Protein-coding gene in the species Homo sapiens

    are implicated in angiogenesis, pulmonary hypertension, cancer, and cardioprotection from ischemia-reperfusion injury. They exhibit an intracellular vesicular

    CLIC4

    CLIC4

    CLIC4

  • Sparassis
  • Genus of fungi

    activity (reverse transcriptase inhibitory activity), neuroprotection, cardioprotection, anti-inflammation, hyperlipidemia, anti-diabetic medication, antimicrobial

    Sparassis

    Sparassis

    Sparassis

  • Lipid emulsion
  • Emulsion of fat for human intravenous use

    potential cardioprotective agent Lou et al. (2014) found that the cardioprotection aspect of Intralipid is initiated by the accumulation of acylcarnitines

    Lipid emulsion

    Lipid emulsion

    Lipid_emulsion

  • SHMOOSE
  • Mitochondria-derived microprotein discovered in 2022

    Humanin and SHMOOSE; potential role of the Humanin–Nox2 interaction in cardioprotection". Frontiers in Nutrition. 12 1727012. Frontiers Media SA. doi:10.3389/fnut

    SHMOOSE

    SHMOOSE

  • Κ-opioid receptor
  • Protein-coding gene in the species Homo sapiens, named for ketazocine

    See Hoe LE, Du Toit EF, Peart JN (April 2015). "Opioid receptors and cardioprotection - 'opioidergic conditioning' of the heart". British Journal of Pharmacology

    Κ-opioid receptor

    Κ-opioid receptor

    Κ-opioid_receptor

  • SOD1
  • Protein-coding gene in humans

    cardioprotective effects. In addition, SOD1 has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioning

    SOD1

    SOD1

    SOD1

  • Platelet
  • Component of blood aiding in coagulation

    "Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection". Seminars in Thrombosis and Hemostasis. 31 (2): 234–246. doi:10.1055/s-2005-869528

    Platelet

    Platelet

    Platelet

  • Nicorandil
  • Chemical compound

    "Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?". Circulation. 97 (24): 2463–2469. doi:10.1161/01.cir.97.24.2463.

    Nicorandil

    Nicorandil

    Nicorandil

  • Intermittent fasting
  • Various systems to schedule meals

    "Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial"

    Intermittent fasting

    Intermittent_fasting

  • Calorie restriction
  • Dietary regime

    Carter CS, Leeuwenburgh C (November 2009). "Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives"

    Calorie restriction

    Calorie_restriction

  • Ursolic acid
  • Pentacyclic chemical compound found in fruits

    atrophy and to stimulate muscular growth in mice, also shows a potential cardioprotection. In mice, ursolic acid induces neural regeneration after sciatic nerve

    Ursolic acid

    Ursolic acid

    Ursolic_acid

  • SGLT2 inhibitor
  • Class of medication

    "SGLT-2 Inhibitors in NAFLD: Expanding Their Role beyond Diabetes and Cardioprotection". International Journal of Molecular Sciences. 23 (6): 3107. doi:10

    SGLT2 inhibitor

    SGLT2_inhibitor

  • Influenza vaccine
  • Vaccine against influenza

    JA (January 13, 2022). "Universal flu vaccines: a shot at lifelong cardioprotection?". Nature Reviews Cardiology. 19 (3): 145–146. doi:10.1038/s41569-021-00670-w

    Influenza vaccine

    Influenza vaccine

    Influenza_vaccine

  • Gerd Heusch
  • German physician, physiologist, and professor

    2020, his long-term collaborator Petra Kleinbongard is professor for cardioprotection at the University of Duisburg-Essen Medical School since 2020. Heusch

    Gerd Heusch

    Gerd_Heusch

  • Wine chemistry
  • Chemistry of wine

    red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection". Journal of Pineal Research

    Wine chemistry

    Wine chemistry

    Wine_chemistry

  • Berkeley
  • Topics referred to by the same term

    California, U.S. Berkeley Test, saliva nitric test for assessing cardioprotection Berkeley Racing Canoe Center, a non-profit organization promoting dragon

    Berkeley

    Berkeley

  • Fatty acid oxidation inhibitors
  • biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction". J. Cardiovasc. Pharmacol. 48 (6):

    Fatty acid oxidation inhibitors

    Fatty_acid_oxidation_inhibitors

  • Δ-opioid receptor
  • Opioid receptor

    the rat model, introduction of DOR ligands results in significant cardioprotection. Until comparatively recently, there were few pharmacological tools

    Δ-opioid receptor

    Δ-opioid receptor

    Δ-opioid_receptor

  • Mitophagy
  • Autophagic process in which mitochondria are delivered to the vacuole and degraded

    Christopher; Gross, Angelina S.; Herbst, Viktoria (December 2016). "Cardioprotection and lifespan extension by the natural polyamine spermidine". Nature

    Mitophagy

    Mitophagy

    Mitophagy

  • SOD2
  • Enzyme

    cardioprotective effects. In addition, SOD2 has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioning

    SOD2

    SOD2

    SOD2

  • Dieting
  • Regulation of the consumption of food

    alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults". The American Journal of Clinical Nutrition. 90 (5):

    Dieting

    Dieting

  • Gingerol
  • Chemical compound

    Elberry AA, Ghareib SA, Azhar A, Banjar ZM, Watson ML (September 2016). "Cardioprotection by 6-gingerol in diabetic rats". Biochemical and Biophysical Research

    Gingerol

    Gingerol

    Gingerol

  • Bilophila wadsworthia
  • Species of bacterium

    there are some benefits to hydrogen sulfide production in the gut like cardioprotection, hydrogen sulfide production also contributes to disease pathology

    Bilophila wadsworthia

    Bilophila_wadsworthia

  • Roberta Gottlieb
  • American oncologist

    mitochondria and mitochondrial biogenesis as essential elements of cardioprotection; efficient removal of damaged mitochondria is important for limiting

    Roberta Gottlieb

    Roberta_Gottlieb

  • Troponin
  • Protein complex

    troponins as biomarkers of drug- and toxin-induced cardiac toxicity and cardioprotection". Expert Opin Drug Metab Toxicol. 1 (4): 715–25. doi:10.1517/17425255

    Troponin

    Troponin

    Troponin

  • ACSF3
  • Protein-coding gene in the species Homo sapiens

    Mulvey JF, Sauchanka O, et al. (2022-09-02). "Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury". Circulation Research

    ACSF3

    ACSF3

    ACSF3

  • Intrinsic cardiac nervous system
  • Cardiac network of neurons and ganglia

    Influences AV node and Purkinje fiber activity for coordinated contraction. Cardioprotection: Responds to ischemia or stress by altering cardiac output. The ICNS

    Intrinsic cardiac nervous system

    Intrinsic_cardiac_nervous_system

  • HRS9531
  • peptide-1/glucose-dependent insulinotropic polypeptide receptor co-agonists for cardioprotection, type 2 diabetes and obesity: a review of mechanisms and clinical data"

    HRS9531

    HRS9531

  • Survival activating factor enhancement
  • red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection". J. Pineal Res. 50 (4): 374–80

    Survival activating factor enhancement

    Survival_activating_factor_enhancement

  • Sandra M. Swain
  • American oncologist

    E. Velez-Garcia, M. S. Ewer, J. R. Bianchine & R. A. Gams (1997). "Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast

    Sandra M. Swain

    Sandra M. Swain

    Sandra_M._Swain

  • BAY 60–6583
  • Chemical compound

    Grenz A, Köhler D, Mittelbronn M, Ledent C, et al. (March 2007). "Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors". Circulation

    BAY 60–6583

    BAY 60–6583

    BAY_60–6583

  • Sodium nitroprusside
  • Medication for lowering blood pressure

    Guanosine Monophosphate Signaling and Phosphodiesterase-5 Inhibitors in Cardioprotection". Journal of the American College of Cardiology. 59 (22): 1921–1927

    Sodium nitroprusside

    Sodium nitroprusside

    Sodium_nitroprusside

  • IRF3
  • Protein-coding gene in the species Homo sapiens

    response as a potential therapeutic target for post-myocardial infarction cardioprotection. IRF3 has been shown to interact with IRF7. GRCh38: Ensembl release

    IRF3

    IRF3

    IRF3

  • Michel Chrétien
  • Canadian medical researcher

    Chrétien’s group is associated with markedly low LDL cholesterol and cardioprotection, work that helped validate PCSK9 as a therapeutic target. Chrétien’s

    Michel Chrétien

    Michel_Chrétien

  • Perfluorocarbon emulsions
  • Unger, Evan C.; Martin, Diego R. (March 2019). "Imaging assessment of cardioprotection mediated by a dodecafluoropentane oxygen-carrier administered during

    Perfluorocarbon emulsions

    Perfluorocarbon_emulsions

  • PER2
  • Protein found in mammals

    PER2 in turn enhances oxygen-efficient glycolysis and hence provides cardioprotection from ischemia. Therefore, it is speculated that strong light may reduce

    PER2

    PER2

    PER2

  • ERA-45
  • Chemical compound

    Tabor C, Black D, Ederveen A, Gray GA (2008). "Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor

    ERA-45

    ERA-45

  • Combined malonic and methylmalonic aciduria
  • Rare metabolic disease

    Murphy, Michael P.; Krieg, Thomas (2022-09-02). "Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury". Circulation Research

    Combined malonic and methylmalonic aciduria

    Combined_malonic_and_methylmalonic_aciduria

  • TAN-67
  • Chemical compound

    Fryer RM, Hsu AK, Nagase H, Gross GJ (August 2000). "Opioid-induced cardioprotection against myocardial infarction and arrhythmias: mitochondrial versus

    TAN-67

    TAN-67

    TAN-67

  • Phosphodiesterase
  • Class of enzymes

    (2018-03-08). "Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection?". Heart. 104 (15): 1244–1250. doi:10.1136/heartjnl-2017-312865. ISSN 1355-6037

    Phosphodiesterase

    Phosphodiesterase

    Phosphodiesterase

  • Beta-1 adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    and response to maximum heart rate during exercise, evident for the cardioprotection related to this polymorphism. Because ADRB-1 plays such a critical

    Beta-1 adrenergic receptor

    Beta-1 adrenergic receptor

    Beta-1_adrenergic_receptor

  • ABT-702
  • Pharmaceutical compound

    "An adenosinergic positive feedback loop extends pharmacological cardioprotection duration". British Journal of Pharmacology. 181 (23): 4920–4936. doi:10

    ABT-702

    ABT-702

    ABT-702

  • Hsp20
  • Protein family

    PMID 21853411. G.C, Fan; G, Chu; EG, Kranies (May 2005). "Hsp20 and its cardioprotection". Trends Cardiovasc. Med. 15 (4): 138–41. doi:10.1016/j.tcm.2005.05

    Hsp20

    Hsp20

  • Histone acetylation and deacetylation
  • Biological processes used in gene regulation

    Stanmore DA, Backs J (May 2014). "Histone deacetylase signaling in cardioprotection". Cellular and Molecular Life Sciences. 71 (9): 1673–90. doi:10

    Histone acetylation and deacetylation

    Histone acetylation and deacetylation

    Histone_acetylation_and_deacetylation

  • CGMP-specific phosphodiesterase type 5
  • Mammalian protein found in humans

    (March 2018). "Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection?". Heart. 104 (15). British Cardiac Society: 1244–1250. doi:10

    CGMP-specific phosphodiesterase type 5

    CGMP-specific phosphodiesterase type 5

    CGMP-specific_phosphodiesterase_type_5

  • Thomas Pieber
  • Endrocrinologist

    S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nature

    Thomas Pieber

    Thomas_Pieber

  • TRPC
  • Family of transient receptor potential cation channels in animals

    (NYR-BI03) – a selective TRPC3/6/7 inhibitor – is under development for cardioprotection (protecting heart tissue after myocardial infarction) and neuroprotection

    TRPC

    TRPC

  • ROMK
  • Potassium channel

    ATP-sensitive potassium (mitoKATP) channel, known to play a critical role in cardioprotection against ischemic-reperfusion injury in the heart as well as in the

    ROMK

    ROMK

    ROMK

  • Peptidylprolyl isomerase A
  • Protein-coding gene in the species Homo sapiens

    complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, PPIA expression is highly

    Peptidylprolyl isomerase A

    Peptidylprolyl isomerase A

    Peptidylprolyl_isomerase_A

  • Diallyl trisulfide
  • Chemical compound

    Bhushan, Shashi; Lefer, David J (2011). "Hydrogen sulfide-mediated cardioprotection: Mechanisms and therapeutic potential". Clinical Science. 120 (6):

    Diallyl trisulfide

    Diallyl_trisulfide

  • Myocardial scarring
  • Fibrous tissue in the heart

    "Cardiotoxicity of Anticancer Drugs: Molecular Mechanisms and Strategies for Cardioprotection". Frontiers in Cardiovascular Medicine. 9 847012. doi:10.3389/fcvm

    Myocardial scarring

    Myocardial scarring

    Myocardial_scarring

  • Myokine
  • Class of proteins produced by muscle

    reductions in insulin sensitivity [200,227,228]. Females achieve superior cardioprotection and all-cause mortality reduction through moderate-intensity regimens

    Myokine

    Myokine

  • Forsythoside B
  • Chemical compound

    PMID 8593444. Jiang WL, Fu FH, Xu BM, Tian JW, Zhu HB (July 2010). "Cardioprotection with forsythoside B in rat myocardial ischemia-reperfusion injury:

    Forsythoside B

    Forsythoside B

    Forsythoside_B

  • Hepatocyte growth factor receptor
  • Mammalian protein found in Homo sapiens

    channels. In the injured heart, HGF/MET axis plays important roles in cardioprotection by promoting pro-survival (anti-apoptotic and anti-autophagic) effects

    Hepatocyte growth factor receptor

    Hepatocyte growth factor receptor

    Hepatocyte_growth_factor_receptor

  • ATP-sensitive potassium channel
  • Family of transport proteins

    5-hydroxydecanoic acid ("5-HD") or MCC-134 completely inhibits the cardioprotection afforded by IPC, and genetic knockout of sarcKATP genes in mice has

    ATP-sensitive potassium channel

    ATP-sensitive_potassium_channel

  • HMR 1883
  • Chemical compound

    , & Marban, E. (2000). The role of mitochondrial KATP channels in cardioprotection. Bas Res Cardiol 95, 285−289 Bohn, H., Englert, H. C., & Schoelkens

    HMR 1883

    HMR_1883

  • Caloric restriction mimetic
  • Hypothetical anti-aging dietary supplement or drug candidate

    Tobias; Harger, Alexandra; Schipke, Julia; Zimmermann, Andreas (2016). "Cardioprotection and lifespan extension by the natural polyamine spermidine". Nature

    Caloric restriction mimetic

    Caloric_restriction_mimetic

  • PPIE (gene)
  • Protein-coding gene in the species Homo sapiens

    complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, cyclophilin expression

    PPIE (gene)

    PPIE (gene)

    PPIE_(gene)

  • Topoisomerase
  • Class of enzymes

    Cvetković RS, Scott LJ (2005). "Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy". Drugs. 65 (7): 1005–1024. doi:10

    Topoisomerase

    Topoisomerase

  • Ankyrin-2
  • Protein-coding gene in the species Homo sapiens

    regulate cardiac ankyrin-B levels, and ankyrin-B is required for normal cardioprotection following ischemia reperfusion injury. ITPR1 HDJ1/HSP40 SPTBN1 OBSCN

    Ankyrin-2

    Ankyrin-2

    Ankyrin-2

  • Adenosine deaminase
  • Mammalian protein found in humans

    during ischemic stress". HIF-1α in the Heart: Provision of Ischemic Cardioprotection and Remodeling of Nucleotide Metabolism (PDF) (PhD). Electronic Theses

    Adenosine deaminase

    Adenosine deaminase

    Adenosine_deaminase

  • Remote ischemic conditioning
  • Experimental medical procedure

    1161/STROKEAHA.123.043279. Heusch, Gerd (2015-02-13). "Molecular Basis of Cardioprotection Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning"

    Remote ischemic conditioning

    Remote_ischemic_conditioning

  • Mitochondrial permeability transition pore
  • Protein pore formed in mitochondria under pathological conditions

    permeability transition pore: molecular nature and role as a target in cardioprotection". Journal of Molecular and Cellular Cardiology. 78: 100–106. doi:10

    Mitochondrial permeability transition pore

    Mitochondrial_permeability_transition_pore

  • Tracy L. Johnson
  • American biochemist and academic

    DeAntonio, J. H., Thayne, K., Ding, J. M., & Lust, R. M. (2013). Cardioprotection via preserved mitochondrial structure and function in the mPer2-mutant

    Tracy L. Johnson

    Tracy_L._Johnson

  • PPIB
  • Protein-coding gene in the species Homo sapiens

    complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. PPIB contributes to the replication

    PPIB

    PPIB

    PPIB

  • Peptidylprolyl isomerase D
  • Protein-coding gene in the species Homo sapiens

    complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, cyclophilin expression

    Peptidylprolyl isomerase D

    Peptidylprolyl isomerase D

    Peptidylprolyl_isomerase_D

  • Adenosine monophosphate deaminase deficiency type 1
  • Metabolic disorder leading to muscle dysfunction

    Skalova, K; Luptak, I; Turcani, M; Hulin, I (2002). "Adenosine and cardioprotection: what can we learn from nature's genetic polymorphism?" (PDF). Bratislavske

    Adenosine monophosphate deaminase deficiency type 1

    Adenosine monophosphate deaminase deficiency type 1

    Adenosine_monophosphate_deaminase_deficiency_type_1

  • Hanoch Senderowitz
  • Israeli chemist

    1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model". Journal of Medicinal Chemistry

    Hanoch Senderowitz

    Hanoch Senderowitz

    Hanoch_Senderowitz

  • Intracrine signaling
  • differentiation. The intracrine actions of VEGF have been implicated in cardioprotection, particularly in response to ischemic stress. Cardiac myocytes exposed

    Intracrine signaling

    Intracrine signaling

    Intracrine_signaling

  • HSPB6
  • Protein-coding gene in the species Homo sapiens

    PMID 18579210. Fan GC, Chu G, Kranias EG (May 2005). "Hsp20 and its cardioprotection". Trends Cardiovasc. Med. 15 (4): 138–41. doi:10.1016/j.tcm.2005.05

    HSPB6

    HSPB6

    HSPB6

  • NOL3
  • Protein-coding gene in the species Homo sapiens

    "Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress". Circulation. 113

    NOL3

    NOL3

    NOL3

  • VDAC3
  • Protein-coding gene in the species Homo sapiens

    remove "unwanted" cells. In addition, VDAC3 has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioning

    VDAC3

    VDAC3

    VDAC3

  • VDAC2
  • Protein-coding gene in the species Homo sapiens

    remove "unwanted" cells. The VDAC2 protein has been implicated in cardioprotection against ischemia-reperfusion injury, such as during ischemic preconditioning

    VDAC2

    VDAC2

    VDAC2

  • Alpha-ketoglutarate-dependent hydroxylases
  • Class of enzymes

    biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction". Journal of Cardiovascular Pharmacology

    Alpha-ketoglutarate-dependent hydroxylases

    Alpha-ketoglutarate-dependent_hydroxylases

  • Ischemic preconditioning
  • Experimental medical technique

    Mangner, Norman; Linke, Axel; Erbs, Sandra; Lurz, Phillip (2015-11-21). "Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning

    Ischemic preconditioning

    Ischemic_preconditioning

  • Purinergic signalling
  • Biological communication between cells involving purine nucleosides and their receptors

    McIntosh VJ, Lasley RD (March 2012). "Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?". Journal of Cardiovascular

    Purinergic signalling

    Purinergic signalling

    Purinergic_signalling

  • PPIC
  • Protein-coding gene in the species Homo sapiens

    complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Similarly, PPIC may confer neuroprotection

    PPIC

    PPIC

    PPIC

  • G protein-coupled receptor kinase
  • Family of protein kinases

    137026 G protein-coupled receptor kinase 5 Polymorphism associated with cardioprotection GRK5 600870 G protein-coupled receptor kinase 6 Knockout mice are supersensitive

    G protein-coupled receptor kinase

    G protein-coupled receptor kinase

    G_protein-coupled_receptor_kinase

  • PPIF
  • Protein-coding gene in the species Homo sapiens

    complex with heat shock proteins. Thus, cyclophilins may function in cardioprotection during ischemia-reperfusion injury. Currently, cyclophilin expression

    PPIF

    PPIF

    PPIF

  • Homeobox protein Nkx-2.5
  • Protein-coding gene in humans

    profoundly involved in the generation of cardiac hypertrophy or in cardioprotection from cytotoxic stress in the adult heart. The NKX2-5 transcription

    Homeobox protein Nkx-2.5

    Homeobox protein Nkx-2.5

    Homeobox_protein_Nkx-2.5

  • Gamma-butyrobetaine dioxygenase
  • Protein-coding gene in the species Homo sapiens

    biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction". Journal of Cardiovascular Pharmacology

    Gamma-butyrobetaine dioxygenase

    Gamma-butyrobetaine dioxygenase

    Gamma-butyrobetaine_dioxygenase

  • Adenosine A3 receptor
  • Cell surface receptor found in humans

    1998). "A physiological role of the adenosine A3 receptor: sustained cardioprotection". Proceedings of the National Academy of Sciences of the United States

    Adenosine A3 receptor

    Adenosine A3 receptor

    Adenosine_A3_receptor

  • Thromboxane receptor
  • Mammalian protein found in Homo sapiens

    at a distance: Involvement of endothelial vasoactive substances in cardioprotection against ischemia-reperfusion injury". Life Sciences. 151: 250–8. doi:10

    Thromboxane receptor

    Thromboxane receptor

    Thromboxane_receptor

  • Epoxyeicosatrienoic acid
  • Class of fatty acids

    Isbell MA, Falck JR, Gross GJ (Aug 2006). "Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury". American Journal of Physiology

    Epoxyeicosatrienoic acid

    Epoxyeicosatrienoic_acid

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