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VDAC3

  • VDAC3
  • Protein-coding gene in the species Homo sapiens

    Voltage-dependent anion-selective channel protein 3 (VDAC3) is a protein that in humans is encoded by the VDAC3 gene on chromosome 8. The protein encoded by this

    VDAC3

    VDAC3

    VDAC3

  • Erastin
  • Molecule initiating ferroptotic cell death

    voltage-dependent anion channels (VDAC) by reversing tubulin's inhibition on VDAC2 and VDAC3, and functionally inhibits the cystine-glutamate antiporter enzyme SLC7A11

    Erastin

    Erastin

    Erastin

  • VDAC1
  • Protein-coding gene in the species Homo sapiens

    shares high structural homology with the other VDAC isoforms (VDAC2 and VDAC3), which are involved in the regulation of cell metabolism, mitochondrial

    VDAC1

    VDAC1

    VDAC1

  • Voltage-dependent anion channel
  • Class of porin ion channels in the outer mitochondrial membrane

    members (genes VDAC1, VDAC2 and VDAC3). Humans, like most higher eukaryotes, encode three different VDACs; VDAC1, VDAC2, and VDAC3. Together with TOMM40 and

    Voltage-dependent anion channel

    Voltage-dependent anion channel

    Voltage-dependent_anion_channel

  • Bcl-2 family
  • Protein family

    porin (VDAC). Interaction of Bcl-2 with VDAC1 or with peptides derived from VDAC3 protects against cell death by inhibiting cytochrome c release. A direct

    Bcl-2 family

    Bcl-2 family

    Bcl-2_family

  • VDAC2
  • Protein-coding gene in the species Homo sapiens

    (2010). "Characterization of human VDAC isoforms: a peculiar function for VDAC3?". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797 (6–7): 1268–75

    VDAC2

    VDAC2

    VDAC2

  • Ferroptosis
  • Type of programmed cell death

    mutant RAS cells. Initial studies characterized the mitochondrial VDAC2 and VDAC3 as the targets of erastin, though it was later found that the mechanistic

    Ferroptosis

    Ferroptosis

  • Index of biophysics articles
  • Index of articles on biophysics

    Two-pore channel Undulatory locomotion Undulipodium VCAM-1 VDAC1 VDAC2 VDAC3 V formation Venkatraman Ramakrishnan Vertical clinging and leaping Vesicle

    Index of biophysics articles

    Index_of_biophysics_articles

  • List of human protein-coding genes 9
  • O14598 18099 VDAC1 HGNC:12669; P21796 18100 VDAC2 HGNC:12672; P45880 18101 VDAC3 HGNC:12674; Q9Y277 18102 VDR HGNC:12679; P11473 18103 VEGFA HGNC:12680;

    List of human protein-coding genes 9

    List_of_human_protein-coding_genes_9

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