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Biological molecule
Twisted intercalating nucleic acid (TINA) is a nucleic acid molecule that, when added to triplex-forming oligonucleotides (TFOs), stabilizes Hoogsteen
Twisted intercalating nucleic acid
Twisted_intercalating_nucleic_acid
Insertion of molecules between DNA
with solvent molecules. Anthracycline Intercalation (chemistry) Molecular tweezers Twisted intercalating nucleic acid Richards, A. D.; Rodgers, A. (2007)
Intercalation_(biochemistry)
Structure formed by double-stranded molecules
formed by double-stranded molecules of nucleic acids such as DNA. The double-helical structure of a nucleic acid complex arises as a consequence of its
Nucleic_acid_double_helix
Molecule that carries genetic information
and ribonucleic acid (RNA) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four
DNA
Topics referred to by the same term
truthinadvertising.org Truth in Negotiations Act, a 1962 US law Twisted intercalating nucleic acid Tina!, a 2008 compilation album by Tina Turner T.I.N.A. (album)
Tina
Structure in molecular biology
(April 2013). "MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer
G-quadruplex
Set of three congruent geometrical helices with the same axis
determine whether a TFO can bind to the gene of interest. Twisted intercalating nucleic acid is sometimes used to improve this process. Mapping of genome-wide
Triple_helix
most commonly assumed by double-stranded nucleic acid molecules, resembling a ladder that has been twisted upon its long axis, with the rungs of the
Glossary of cellular and molecular biology (0–L)
Glossary_of_cellular_and_molecular_biology_(0–L)
Amount of twist in a particular DNA strand
to also play a role in gene expression. Based on the properties of intercalating molecules, i.e. fluorescing upon binding to DNA and unwinding of DNA
DNA_supercoil
Cytosine-rich quadruplex DNA structure
slightly acidic pH (between 4.2 and 5.2), some i-motifs have been found to form at neutral pH, when a free proton is used by the nucleic acids during the
I-motif_DNA
One of many possible double helical structures of DNA
their innate ability in binding nucleic acid. Furthermore, different Zα domains bind to the Z conformation of nucleic acid differently providing important
Z-DNA
Class of enzymes
Crick FH (April 1953). "Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid". Nature. 171 (4356): 737–738. Bibcode:1953Natur
Topoisomerase
Phenomenon in genetics
Isaacs, S. T.; Hearst, J. E. (1985). "Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry"
Crosslinking_of_DNA
Basic structural unit of DNA packaging in eukaryotes
Approach: Structural Engineering of Nucleic Acids by Disulfide Cross-Linking". In Eckstein F, Lilley DM (eds.). Nucleic Acids and Molecular Biology. Vol. 8
Nucleosome
Region within a prokaryotic cell containing genetic material
"Time-dependent bending rigidity and helical twist of DNA by rearrangement of bound HU protein". Nucleic Acids Research. 41 (17): 8280–8. doi:10.1093/nar/gkt593
Nucleoid
Mammalian protein found in humans
complete cancer genomes in the Catalogue of Somatic Mutations in Cancer". Nucleic Acids Research. 39 (Database issue): D945–D950. doi:10.1093/nar/gkq929. PMC 3013785
Catenin_beta-1
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