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In cell biology, single-cell variability occurs when individual cells in an otherwise similar population differ in shape, size, position in the cell cycle
Single-cell_variability
Study of biochemical processes in an individual cell
cell biology, single-cell analysis and subcellular analysis refer to the study of genomics, transcriptomics, proteomics, metabolomics, and cell–cell interactions
Single-cell_analysis
Examines sequence information from individual cells
genetically clonal. Still, single-cell sequencing of RNA or epigenetic modifications can reveal cell-to-cell variability that may help populations rapidly
Single-cell_sequencing
Variation in the time intervals between heartbeats
Heart rate variability (HRV) is the physiological phenomenon of variation in the time interval between heartbeats. It is measured by the variation in
Heart_rate_variability
Computational methods in biology
each cell type Cell sorting List of single cell omics methods Multiomics Single-cell analysis Single-cell transcriptomics Single-cell variability Adossa
Single-cell multi-omics integration
Single-cell_multi-omics_integration
Malaysian haematologist
two QTLs (6q and 2p), and a single-nucleotide polymorphism on the HBB cluster account for around half of the variability in HbF levels. She established
Swee_Lay_Thein
Mathematical models representing biological cells
easy integration of cell level processes such as cell division, intracellular processes and single-cell variability within a cell population. Continuum-based
Cell-based_models
Tropical atmospheric circulation feature
associated with the seasonal variability of the Hadley circulation cause monsoons. The sinking branches of the Hadley cells give rise to the oceanic subtropical
Hadley_cell
Difference in DNA among individuals or populations
during meiosis and more genetic variability in one's offspring. However, this phenomenon can also prove difficult for cell division. Diffuse centromeres
Genetic_variation
Range of possible values for any characteristic of human beings
Human variability, or human variation, is the range of possible values for any characteristic, physical or mental, of human beings. Frequently debated
Human_variability
Analysis technique of genes
Single-cell transcriptomics examines the gene expression level of individual cells in a given population by simultaneously measuring the RNA concentration
Single-cell_transcriptomics
Global climate phenomenon
climate change science, ENSO is known as one of the internal climate variability phenomena. Future trends in ENSO due to climate change are uncertain
El_Niño–Southern_Oscillation
Oldest cultured human cell line (1951)
an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. HeLa cells are durable and
HeLa
Domain of life whose cells have nuclei
in size from single-celled organisms to huge trees and whales Prokaryotes (small cylindrical cells, bacteria, on left) and a single-celled eukaryote, Paramecium
Eukaryote
Genus of viruses
surface of the cell to obtain their envelope and leave the cell. The most common form of evolution for hantaviruses is mutations through single nucleotide
Hantavirus
Organelle in eukaryotic cells responsible for respiration
stochastic processes in the cell to increase the cell-to-cell variability in mutant load as an organism develops: a single egg cell with some proportion of
Mitochondrion
Human retrovirus, cause of AIDS
many variants of HIV in a single infected patient in the course of one day. This variability is compounded when a single cell is simultaneously infected
HIV
Viral pulmonary disease of humans
surface of the cell to obtain their envelope and leave the cell. The most common form of evolution for hantaviruses is mutations through single nucleotide
Hantavirus_pulmonary_syndrome
Medical procedure to replace blood or immune stem cells
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral
Hematopoietic stem cell transplantation
Hematopoietic_stem_cell_transplantation
Process of separating populations of cells
March 2019). "Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting". PLOS ONE.
Cell_sorting
Treatment of cancer using drugs that inhibit cell division or kill cells
of genetically identical cells varying in phenotype, cellular response, and drug sensitivity. Cell-to-cell response variability has been attributed to random
Chemotherapy
Type of photovoltaic
BHJs are ordered nanomaterials for solar cells, or ordered heterojunctions (OHJs). OHJs minimize the variability associated with BHJs. OHJs are generally
Organic_solar_cell
Cancerous overproduction of T cells
of T-cell lymphoma can vary drastically based on the specific type of lymphoma and its growth patterns. Due to their rarity and high variability between
T-cell_lymphoma
Random variability in quantities arising in cellular biology
Cellular noise is random variability in quantities arising in cellular biology. For example, cells which are genetically identical, even within the same
Cellular_noise
Study of epigenomics in individual cells by single cell sequencing
separate cells based on their cell types, uncover sources of cell-to-cell variability, and show a link between chromatin organization and cell-to-cell variation
Single_cell_epigenomics
Form of programmed cell death
off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. Biochemical
Apoptosis
Different genetic causes for the same disease
this variability. Single-cell RNA sequencing has revealed differences in transcriptional activity that may play a role in processes such as cell differentiation
Genetic_heterogeneity
Electrical component that can break an electrical circuit
in the electronics industry such as "single-pole, single-throw" (SPST) (the simplest type, "on or off") or "single-pole, double-throw" (SPDT), connecting
Switch
Cell organelle that packages proteins for export
apparatus varies among eukaryotes. In mammals, a single Golgi apparatus is usually located near the cell nucleus, close to the centrosome. Tubular connections
Golgi_apparatus
Formation of blood cellular components
of mouse haematopoietic progenitor cells, underlying stochastic variability in the distribution of Sca-1, a stem cell factor, subdivides the population
Haematopoiesis
Genetic diversity in human populations
this variation accounts for a small portion (~15%) of human genome variability. The majority of variation exists within the members of each human population
Human_genetic_variation
Type of cell within the eye
inhibition results in a depressed rate of firing. There is wide variability in ganglion cell types across species. In primates, including humans, there are
Retinal_ganglion_cell
Biological process
prokaryotic cell (or organelle) by dividing the cell into two parts, each with the potential to grow to the size of the original. The single DNA molecule
Fission_(biology)
Early embryonic mass that gives rise to the fetus
what are known as inside and outside cells and thus cell lineage specification. However, due to the variability and regulative nature of mammalian embryos
Inner_cell_mass
Electronic device
Joan; Perez-Murano, Francesc (2017). "Exploring the Influence of Variability on Single-Electron Transistors Into SET-Based Circuits". IEEE Transactions
Single-electron_transistor
Species of virus
segments to occur, whereby segments from different lineages mix in a single host cell and produce hybrid progeny. For Seoul virus, this has been observed
Seoul_virus
Eukaryotes other than animals, plants or fungi
from which land plants, animals, and fungi evolved. They are primarily single-celled, exhibiting a wide range of forms such as amoebae, ciliates, thick-walled
Protist
Property of genes where transcription from DNA to RNA occurs in "bursts"
L (2015). "Control of Transcript Variability in Single Mammalian Cells". Cell. 163 (7): 1596–610. doi:10.1016/j.cell.2015.11.018. PMID 26687353. Losick
Transcriptional_bursting
Largest known protein in human muscles
contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Considerable variability exists in the I-band, the
Titin
Type of rechargeable battery
low as 0.9 volts, Ni–Cd cells and alkaline cells are typically interchangeable for most applications. In addition to single cells, batteries exist that
Nickel–cadmium_battery
Genus of algae
iron and manganese compounds. The cell nucleus is located in the middle of the cell. Each semicell contains a single axial chloroplast dotted with several
Closterium
Biological analysis approach
Lubling, Yaniv; Nagano, Takashi (October 2013). "Single-cell Hi-C reveals cell-to-cell variability in chromosome structure". Nature. 502 (7469): 59–64
Multiomics
Solid, liquid or gel used to grow microorganisms or cells
but can lead to variability and contamination issues. Fetal bovine serum (FBS) is commonly used due to its high capacity to support cell growth, although
Growth_medium
Repeating unit of a myofibril in a muscle cell
between species and between muscles in a single individual. The reasons for the lack of substantial sarcomere variability in vertebrates is not fully known.[citation
Sarcomere
Genus of green algae
a genus of about thirteen species of single-celled or colonial green algae of the division Chlorophyta. The cells are spherical in shape, about 2 to 10
Chlorella
Species of virus
negative-sense, single-stranded RNA virus. Its name is derived from the large, multinucleated cells known as syncytia that form when infected cells fuse. RSV
Respiratory_syncytial_virus
Variety and variability of life forms
Biodiversity is the variability of life on Earth. It can be measured on various levels, for example, genetic variability, species diversity, ecosystem
Biodiversity
Group of clinically similar illnesses caused by species of hantaviruses
from the cell surface to obtain their envelope and leave the cell. The most common form of evolution for hantaviruses is mutations through single nucleotide
Hantavirus hemorrhagic fever with renal syndrome
Hantavirus_hemorrhagic_fever_with_renal_syndrome
Malignant tumor characterized by uncontrolled cell growth in lung tissue
damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply
Lung_cancer
Genes on human chromosome 6
(HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. The HLA
Human_leukocyte_antigen
Single-Cell RNA-Sequencing Method
high-throughput, single-cell RNA sequencing (scRNA-seq) technology used to analyze the mRNA expression of thousands of individual cells by separating them
Drop-Seq
Theory of early hominid migration
commonly attributed to the remains is 67,000 years ago. High rates of variability yielded by various dating techniques carried out by different researchers
Recent African origin of modern humans
Recent_African_origin_of_modern_humans
Plant organelle that conducts photosynthesis
plant cell. If the cell divides, chloroplast division provides the additional chloroplasts to partition between the two daughter cells. In single-celled algae
Chloroplast
Photographic display of total chromosome complement in a cell
potentially be sex chromosomes. Polyploid cells have multiple copies of chromosomes and haploid cells have single copies. Karyotypes can be used for many
Karyotype
Protein(s) forming a major part of an organism's immune system
essential for its ability to invade a host cell). Antibodies may be borne on the surface of an immune cell, as in a B cell receptor, or they may exist freely
Antibody
Genetic trait in fungi and algae
different cells of a single mycelium. It can be contrasted to heterothallic. It is often used to categorize fungi. In yeast, heterothallic cells have mating
Homothallism
Neuron communication by electric impulses
cells, which include animal cells like neurons and muscle cells, as well as some plant cells. Certain endocrine cells such as pancreatic beta cells,
Action_potential
Confinement of Single Cells of Bacteria in Small Volumes Initiates High-Density Behavior of Quorum Sensing and Growth and Reveals Its Variability". Angewandte
Cell culturing in open microfluidics
Cell_culturing_in_open_microfluidics
Interconnected biochemical reactions releasing energy
citric acid cycle is in general highly conserved, there is significant variability in the enzymes found in different taxa (note that the diagrams on this
Citric_acid_cycle
Gonadotropin secreted by the adenohypophysis
lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by
Luteinizing_hormone
Investigative procedure in microbiology
chemical and physical properties of their cell walls. Gram-positive cells have a thick layer of peptidoglycan in the cell wall that retains the primary stain
Gram_stain
Medical condition
to cellular energy production, increases oxidative stress and cell death. PD has no single cause: rather, genetic and environmental factors interact and
Pathophysiology of Parkinson's disease
Pathophysiology_of_Parkinson's_disease
Fast-flowing atmospheric air current
several decades to definitively distinguish various forms of natural variability from climate trends. This point was stressed by reviews in 2013 and in
Jet_stream
Developmental biological concept
a complex organ, variability in gene expression may be required to contribute to differentiation of multiple cell types from cells that have equivalent
Developmental_noise
Epigenetic phenomenon
a lymphoid cell into a myeloid cell was C/EBPα. MyoD and C/EBPα are examples of a small number of single factors that can transform cells. More often
Reprogramming
Chromosomal disorder in which there are three copies of chromosome 13
Ductus Arteriosus) Dextrocardia Single umbilical artery Trisomy 13 is the cause of Patau syndrome, which means each cell in the body has three copies of
Patau_syndrome
pseudo-bulk sample and or cell level single cell libraries. This loses however the information on the variability of the cells. Optimal transport theory
Disease_Cell_Atlas
Type of immunotherapy
eliminated. Upon injection, these homogenous antibodies produced from a single B cell can target a specific epitope on the antigen. The major advantage of
Passive_antibody_therapy
Physical effects resulting from activation of the immune system
cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out damaged cells
Inflammation
Blood test
Smock, KJ in Greer et al. 2018, Ch. 1 § Cell counts Ruemke, C. L. (1978). "The statistically expected variability in differential leukocyte counting" (PDF)
White_blood_cell_differential
Microscopic living organism
organism of microscopic size, which may exist in its single-celled form or as a colony of cells. The possible existence of unseen microbial life was suspected
Microorganism
Fusion of natural selection with Mendelian inheritance
unifying cell biology, genetics, and both micro and macroevolution. His work emphasized that real-world populations had far more genetic variability than
Modern synthesis (20th century)
Modern_synthesis_(20th_century)
Medical condition
Giliani S, Gu Y, Mazzolari E, Bates A, Pegoiani E, et al. (2008). "Variability of clinical and laboratory features among patients with ribonuclease
Cartilage–hair_hypoplasia
Topics referred to by the same term
contains members with varying chromosome counts or shapes Cell polymorphism, variability in size of cells or nuclei Gene polymorphism, the existence of more
Polymorphism
X chromosome monosomy
The phenotype of Turner syndrome is affected by mosaicism, where cell lines with a single sex chromosome are combined with those with multiple. Individuals
Turner_syndrome
Form of kidney cancer
Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney
Renal_cell_carcinoma
Family of regulator genes
large B-cell lymphoma (DLBCLs), an aggressive Non-Hodgkin Lymphoma (NHL). Patients with MYC-R have inferior outcomes and can be classified as single-hit,
Myc
Large-scale study of proteins
analysis of proteomes, both in large samples composed of millions of cells, and in single cells. Proteins are vital macromolecules of all living organisms, with
Proteomics
Neuromuscular disease
mutations in over 100 different genes, which disrupt the function of nerve cells' axons (responsible for transmitting signals) and their myelin sheaths (which
Charcot–Marie–Tooth_disease
Biological process of getting older
potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of
Ageing
Subspecies of mammal
parallel sequencing approach uncovers ancient origins and high genetic variability of endangered Przewalski's horses". Genome Biology and Evolution. 3:
Przewalski's_horse
Design of experiments to collect similar contexts together
These variables are chosen carefully to minimize the effect of their variability on the observed outcomes. There are different ways that blocking can
Blocking_(statistics)
Photosynthetic process in some plants
deserts of the Middle East. These plants have been shown to operate single-cell C4 CO2-concentrating mechanisms, which are unique among the known C4
C4_carbon_fixation
Union of opposite-sex gametes in sexual reproduction to form a zygote
nature is increased genetic variability that promotes adaptation or avoidance of extinction (see Genetic variability). Cell fusion Conception cap Conception
Fertilisation
Production of sperm
These cells are called spermatogonial stem cells. The mitotic division of these produces two types of cells. Type A cells replenish the stem cells, and
Spermatogenesis
Theory regarding color vision in humans
and the same type of opponent cell." Webster et al. and Wuerger et al. have conclusively re-affirmed that single-cell spectrally opposed responses do
Opponent_process
information on spatial variability and supports management decisions for producers. Grain mass flow is most commonly measured using a load cell with an impact
Grain_yield_monitor
Fusion of the nuclei of two haploid eukaryotic cells
four new haploid gamete cells. One possible advantage of sexual reproduction is that it results in more genetic variability, providing the opportunity
Karyogamy
Allotropes of carbon with a cylindrical nanostructure
are also generated to incorporate variability such as waviness, orientation and agglomeration of multiwall or single-wall carbon nanotubes. There are many
Carbon_nanotube
System of surface and deep currents in the Atlantic Ocean
1980, and a single-sverdrup reduction in AMOC strength did not occur until 1980, a variation that remains within range of natural variability. Sediment
Atlantic meridional overturning circulation
Atlantic_meridional_overturning_circulation
Adaptive immunity variety-generation process
cell maturation. It results in the highly diverse repertoire of antibodies/immunoglobulins and T cell receptors (TCRs) found in B cells and T cells,
V(D)J_recombination
Genus of algae
cell, but single cells (unicells) may be found as well. These single cells may be confused with Lagerheimia, a genus of single-celled algae. The cell
Desmodesmus
Species of parasite that causes sexually transmitted infections
New population studies and genomic sequences illustrate the genetic variability of the parasite and the parasite's possible resistance to treatment.
Trichomonas_vaginalis
Group of brain diseases induced by prions
tauopathy similar to that seen in Alzheimer's disease, highlighting the variability diseases presentation. Despite this variation, all prion diseases share
Transmissible spongiform encephalopathy
Transmissible_spongiform_encephalopathy
Informal grouping of virus species
lysis of the cell (in this case, a lymphocyte). The virion is spherical to pleomorphic, about 80-100 nm in diameter. Unusually, the single-stranded RNA
Primate_T-lymphotropic_virus
Species of virus affecting humans and animals
the disease severity and the genetic nature of the virus. Hence the variability in the severity of illness was suspected to correlate with genetic differences
Zaire_ebolavirus
Nitrogen-fixing cells
between the cells in the filament. Heterocysts maintain photosystem I, allowing them to generate ATP by cyclic photophosphorylation. Single heterocysts
Heterocyst
Biological process of yeast
yeast), are single-celled eukaryotes that can exist as either haploid cells, which contain a single set of chromosomes, or diploid cells, which contain
Mating_of_yeast
Observation of the diversity of tumour cells
observed between tumour cells is the result of differences in the stem cells from which they originated. Stem cell variability is often caused by epigenetic
Tumour_heterogeneity
Inactivation of copies of X chromosome
possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated in a particular embryonic cell is random
X-inactivation
SINGLE CELL-VARIABILITY
SINGLE CELL-VARIABILITY
Female
English
Variant spelling of English Belle, BELL means "beautiful."Â
Surname or Lastname
English
English : occupational name for someone who laid wooden tiles (shingles) on roofs, from an agent derivative of Middle English schingle ‘shingle’.
Surname or Lastname
English
English : perhaps a metonymic occupational name for a spindle maker, from Middle English spindle, spindel (Old English spinel).Americanized spelling of German and Jewish Spindel.
Surname or Lastname
English
English : from Middle English sengler, syngler ‘singular’ (Old French se(i)ngler), perhaps a nickname for a solitary person.German : topographic name for a valley dweller, from a diminutive of Middle High German senke ‘valley’ + the suffix -er, denoting an inhabitant.German : habitational name for someone from Singeln near Waldshut.German : variant of Sing 1.
Surname or Lastname
English
English : topographic name for someone who lived in a small valley, from Middle English, Old English dell ‘dell’, ‘valley’, or a habitational name from any of several minor places named Dell, from this word, for example in Buckinghamshire, Essex, and Sussex.German : from Low German delle ‘dell’, ‘depression’ (Middle High German telle ‘gorge’).
Female
English
Pet form of English Eleanor, NELL means "foreign; the other."
Surname or Lastname
English
English : variant of Ingle.
Male
Norwegian
Norwegian form of Old Norse Sindri, possibly SINDRE means "sparkling."
Male
English
Short form of English unisex Kelly, KELL means "bright-headed."
Surname or Lastname
English
English : from either of two Old Norse personal names: Ingjaldr, in which the prefix in- probably reinforces the element -gjaldr, related to Old Norse gjalda ‘to pay or recompense’, or Ingólfr ‘Ing’s wolf’ (Ing was an ancient Germanic fertility god).English : habitational name from Ingol in Lancashire, which is named from the Old English personal name Inga + holh ‘hollow’, ‘depression’.Probably a variant of German Ingel, from a short form of any of several Germanic personal names formed with Ing- (see 1 above).An early bearer, Richard Ingle (1609–c. 1653), was a rebel and a pirate who first came to the colonies in 1631 or 1632 as a tobacco merchant. He is known to have practiced piracy in MD.
Surname or Lastname
English
English : occupational name from an agent derivative of Middle English tingle (see Tingle).German : occupational or status name for a medieval judge or court official, from Old High German ding ‘legal proceeding’.German : variant of Tengler.
Surname or Lastname
English (chiefly northern)
English (chiefly northern) : topographic name for someone who lived by an area of high ground or by a prominent crag, from northern Middle English fell ‘high ground’, ‘rock’, ‘crag’ (Old Norse fjall, fell).English, German, and Jewish (Ashkenazic) : metonymic occupational name for a furrier, from Middle English fell, Middle High German vel, or German Fell or Yiddish fel, all of which mean ‘skin’, ‘hide’, or ‘pelt’. Yiddish fel refers to untanned hide, in contrast to pelts ‘tanned hide’ (see Pilcher).
Surname or Lastname
English
English : topographic name for someone who lived in a place cleared of woods by fire, from Middle English sengle ‘burnt clearing’.German : from a pet form of a short form of a Germanic person name formed with sing ‘sing’ as the first element.
Surname or Lastname
English
English : topographic name for someone living in a small wooded dell or hollow, Middle English dingle (of uncertain origin). There is a district of Liverpool called Dingle.South German : nickname or status name for a smallholder, from Middle High German dingelīn ‘smallholding’.Americanized spelling of the old Prussian name Dingel or Dyngele, possibly from Germanic thing ‘legal assembly’.
Surname or Lastname
English
English : habitational name from a place in Northamptonshire named Dingley, possibly from Middle English dingle ‘hollow’ + Old English lēah ‘woodland clearing’.
Surname or Lastname
English
English : from the Old English personal name Hringwulf.German : from a short form of a Germanic personal name based on hring ‘ring’.German : metonymic occupational name for a ring maker (see Ringler).German : altered spelling of Ringel, an Old Prussian personal name.
Surname or Lastname
English
English : metonymic occupational name for a worker in the linen or hemp industry, from Middle English swingle ‘swingle’, a wooden implement used for beating flax or hemp (Middle Dutch swinghel, from the verb ‘to swing’).Possibly an Americanized spelling of German Zwingel, a topographic name from Middle High German zwingel ‘citadel’.
Surname or Lastname
English
English : topographic name for someone who lived near a spring or stream, Middle English well(e) (Old English well(a)).German : from a short form of the personal names Wallo, Walilo.German : nickname from Middle High German wël ‘round’.
Surname or Lastname
English (West Midlands)
English (West Midlands) : occupational name for a worker in the linen or hemp industry, from an agent derivative of Middle English swingle ‘swingle’ (see Swingle).
Surname or Lastname
English
English : metonymic occupational name for a maker of nails or pins, or nickname for a small, thin man, from Middle English tingle, a kind of very small nail (of North German origin).
SINGLE CELL-VARIABILITY
SINGLE CELL-VARIABILITY
Boy/Male
Indian, Kannada, Mythological, Traditional
Lord Vishnu
Boy/Male
Muslim/Islamic
Of mercy
Surname or Lastname
English
English : occupational name for a maker of wheels (for vehicles or for use in spinning or various other manufacturing processes), from an agent derivative of Middle English whele ‘wheel’. The name is particularly common on the Isle of Wight; on the mainland it is concentrated in the neighboring region of central southern England.A founder of Salisbury, NH, in 1634 was John Wheeler.
Girl/Female
Hindu, Indian
Pride
Boy/Male
Indian, Sanskrit
With Bay Horses
Girl/Female
Hindu, Indian, Traditional
Innocense
Boy/Male
French
Red haired.
Girl/Female
Hindu, Indian, Kannada, Telugu
Peacock
Girl/Female
Latin
Loved by God.
Boy/Male
Hindu
Peace-lover, Warm, Mediator
SINGLE CELL-VARIABILITY
SINGLE CELL-VARIABILITY
SINGLE CELL-VARIABILITY
SINGLE CELL-VARIABILITY
SINGLE CELL-VARIABILITY
n. & v.
See Jingle.
imp. & p. p.
of Jingle
n.
A cell; a house.
a.
Hence, unmarried; as, a single man or woman.
n.
Same as Cella.
n. pl.
See Single, n., 2.
imp. & p. p.
of Mingle
v. i.
To take the irrregular gait called single-foot;- said of a horse. See Single-foot.
n.
An irregular gait of a horse; -- called also single-footed pace. See Single, v. i.
a.
One only, as distinguished from more than one; consisting of one alone; individual; separate; as, a single star.
a.
Simple; not wise; weak; silly.
a.
Not doubled, twisted together, or combined with others; as, a single thread; a single strand of a rope.
v. t.
To place or inclose in a cell.
n.
A unit; one; as, to score a single.
imp. & p. p.
of Single
v. t.
To cause to give a sharp metallic sound as a little bell, or as coins shaken together; to tinkle.
a.
Having a single purpose; hence, artless; guileless; single-hearted.
v. t.
To cover with shingles; as, to shingle a roof.
adv.
Without partners, companions, or associates; single-handed; as, to attack another singly.
a.
Performed by one person, or one on each side; as, a single combat.