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Schaffer collaterals are axon collaterals given off by CA3 pyramidal cells in the hippocampus. These collaterals project to area CA1 of the hippocampus
Schaffer_collateral
Part of the brain of mammals
Schaffer collaterals similar to CA3 pyramidal cells. Amaral showed that the mossy cells in the CA4 of Lorente de Nó did not have schaffer collaterals
Hippocampal_subfields
Neural circuit in the hippocampus
pyramidal cells in CA3 via mossy cell fibers. CA3 then fires to CA1 via Schaffer collaterals which synapse in the subiculum and are carried out through the fornix
Trisynaptic_circuit
Persistent strengthening of synapses based on recent patterns of activity
anatomic location in which LTP is observed. For example, LTP in the Schaffer collateral pathway of the hippocampus is NMDA receptor-dependent - this was
Long-term_potentiation
synaptic activity originating from a different brain region, the Schaffer collateral. Astrocytes integrate and modulate information from their synaptic
Tripartite_synapse
Nerve fiber part
"Vesicular release probability sets the strength of individual Schaffer collateral synapses". Nature Communications. 13 (1): 6126. doi:10.1038/s41467-022-33565-6
Axon_terminal
Hungarian anatomist and neurologist
Vienna. The axon projection from CA3 to CA1 neurons in hippocampus, Schaffer collateral, is named after him. He was involved in the early studies of Tay–Sachs
Károly_Schaffer
In neurophysiology, a reduction of neuronal synapse efficacy
affects hippocampal synapses between the Schaffer collaterals and the CA1 pyramidal cells. LTD at the Schaffer collateral-CA1 synapses depends on the timing
Long-term_depression
Chemical compound
learning-impaired, aging rat models. It has been shown to increase Schaffer collateral-CA1 long-term potentiation in vitro. In concert with a learning task
Rapastinel
Protein involved in the breakdown of blood clots
exosome extracellular space collagen-containing extracellular matrix Schaffer collateral - CA1 synapse glutamatergic synapse Biological process negative regulation
Tissue-type plasminogen activator
Tissue-type_plasminogen_activator
Protein found in humans
cell-cell junction ruffle plasma membrane COP9 signalosome lamellipodium Schaffer collateral - CA1 synapse glutamatergic synapse intracellular anatomical structure
PLCG1
Electrical signal encouraging a neuron to fire
the field EPSP (fEPSP) in stratum radiatum of CA1 in response to Schaffer collateral stimulation. This is the signal seen by an extracellular electrode
Excitatory postsynaptic potential
Excitatory_postsynaptic_potential
Protein-coding gene in the species Homo sapiens
anchored component of synaptic vesicle membrane presynapse cytoskeleton Schaffer collateral - CA1 synapse extrinsic component of synaptic vesicle membrane Biological
Synapsin_I
Protein-coding gene in the species Homo sapiens
projection neuron projection perikaryon synapse postsynaptic membrane Schaffer collateral - CA1 synapse glutamatergic synapse integral component of presynaptic
PTPRS
Protein-coding gene in the species Homo sapiens
neuron projection Golgi apparatus presynaptic active zone membrane Schaffer collateral - CA1 synapse glutamatergic synapse plasma membrane dendritic spine
APBA1
Protein found in humans
adherens extracellular exosome nucleus lamellipodium catenin complex Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse presynaptic
P120_catenin
Component of brain anatomy
and contralateral CA1 regions through a set of fibers called the Schaffer collaterals, and commissural pathway, respectively. Region CA1 receives input
Hippocampus_anatomy
Peptide hormone involved in appetite regulation
extracellular region axon secretory granule lumen extracellular space Schaffer collateral - CA1 synapse glutamatergic synapse Biological process positive regulation
Ghrelin
Protein-coding gene in the species Homo sapiens
presynaptic membrane cytoplasmic vesicle neuromuscular junction Schaffer collateral - CA1 synapse perinuclear region of cytoplasm Biological process
Synaptophysin
Protein found in humans
complex dendrite cell projection dendritic spine postsynaptic membrane Schaffer collateral - CA1 synapse Biological process phosphorylation interferon-gamma-mediated
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Calcium/calmodulin-dependent_protein_kinase_type_II_subunit_alpha
Structure connecting neurons in the nervous system
chicks Calyx of Held in the brainstem Ribbon synapse in the retina Schaffer collateral synapses in the hippocampus. These synapses are small, but their
Synapse
"Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses". Proceedings of the National Academy of Sciences. 115 (21):
Glutamate-sensitive fluorescent reporter
Glutamate-sensitive_fluorescent_reporter
Biological process that adjusts the strength of connections between neurons in the brain
(2021-01-30). "Impairment of Spike-Timing-Dependent Plasticity at Schaffer Collateral-CA1 Synapses in Adult APP/PS1 Mice Depends on Proximity of Aβ Plaques"
Spike-timing-dependent plasticity
Spike-timing-dependent_plasticity
Protein
axon cytoplasm microtubule cytoskeleton midbody asymmetric synapse Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
Dysbindin
Mammalian protein found in Homo sapiens
alpha3-beta1 complex membrane raft focal adhesion glial cell projection Schaffer collateral - CA1 synapse glutamatergic synapse integral component of synaptic
Integrin_beta_1
Protein-coding gene in the species Homo sapiens
projection intermediate filament axon cytoplasm neuromuscular junction Schaffer collateral - CA1 synapse cholinergic synapse postsynaptic intermediate filament
Neurofilament light polypeptide
Neurofilament_light_polypeptide
Subgroup of serine proteases
"Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo". The Journal
Kallikrein
Protein-coding gene in the species Homo sapiens
terminal bouton axon membrane raft neuron projection plasma membrane Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse integral component
P2RX3
Protein-coding gene in humans
membrane extracellular exosome cell surface catenin complex synapse Schaffer collateral - CA1 synapse glutamatergic synapse Biological process homophilic
CDH11
Protein-coding gene in the species Homo sapiens
membrane cell surface neuron projection membrane raft plasma membrane Schaffer collateral - CA1 synapse postsynapse glutamatergic synapse integral component
Growth hormone secretagogue receptor
Growth_hormone_secretagogue_receptor
Protein-coding gene in the species Homo sapiens
component of plasma membrane nucleolus protein-containing complex Schaffer collateral - CA1 synapse glutamatergic synapse GABA-ergic synapse integral component
NRXN1
Protein domain
synapse cell junction extracellular exosome protein-containing complex Schaffer collateral - CA1 synapse glutamatergic synapse postsynaptic density, intracellular
BCR_(gene)
Protein-coding gene in the species Homo sapiens
vesicle membrane secretory granule membrane protein-containing complex Schaffer collateral - CA1 synapse Biological process release of sequestered calcium ion
ITPR1
Protein-coding gene in the species Homo sapiens
focal adhesion plasma membrane integral component of plasma membrane Schaffer collateral - CA1 synapse glutamatergic synapse integral component of presynaptic
Ephrin_B2
Protein-coding gene in the species Homo sapiens
integral component of membrane cytosol membrane plasma membrane axon Schaffer collateral - CA1 synapse integral component of postsynaptic density membrane
Netrin_receptor_DCC
Frey and Morris involved the stimulation of two different sets of Schaffer collateral fibers that synapsed on same population of CA1 cells. They then recorded
Synaptic_tagging
Protein-coding gene in the species Homo sapiens
plasma membrane integral component of plasma membrane early endosome Schaffer collateral - CA1 synapse integral component of postsynaptic density membrane
Beta-1_adrenergic_receptor
Protein-coding gene in the species Homo sapiens
plasma membrane cell junction dendrite asymmetric synapse synapse Schaffer collateral - CA1 synapse glutamatergic synapse cholinergic synapse integral
Muscarinic acetylcholine receptor M1
Muscarinic_acetylcholine_receptor_M1
Protein found in humans
cytosol cell surface postsynaptic density cerebellar mossy fiber Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
CACNG2
Protein-coding gene in humans
complex mitochondrial inner membrane cytosol postsynaptic density Schaffer collateral - CA1 synapse glutamatergic synapse transcription regulator complex
STAT3
fluid, Foramina of Scarpa, Scarpa's ganglion Károly Schaffer 1864–1939 Hungary Schaffer collateral Andrew Schally 1926–2024 France Nobel Prize in Physiology
List_of_neuroscientists
Finally, the axons of the pyramidal cells in the CA3 regions, the Schaffer collateral pathway (CA1), terminate on the pyramidal cells of the CA1 region
Early_long-term_potentiation
Vertebrate brain region
cell fibers to CA3 (second synapse). From there, CA3 axons called Schaffer collaterals leave the deep part of the cell body and loop up to the apical dendrites
Hippocampus
Protein-coding gene in humans
SNARE complex protein-containing complex presynapse calyx of Held Schaffer collateral - CA1 synapse postsynapse glutamatergic synapse terminal bouton Biological
CPLX1
Protein-coding gene in humans
presynaptic membrane nucleus basement membrane cell-cell junction Schaffer collateral - CA1 synapse Biological process negative regulation of cellular
CASK
Protein-coding gene in the species Homo sapiens
protein-containing complex intracellular membrane-bounded organelle Schaffer collateral - CA1 synapse glutamatergic synapse intracellular anatomical structure
RAB11A
Protein-coding gene in the species Homo sapiens
exosome nucleus cytoplasm nucleoplasm protein-containing complex Schaffer collateral - CA1 synapse glutamatergic synapse Biological process negative regulation
PRKCI
Protein-coding gene in the species Homo sapiens
platelet alpha granule lumen extracellular space mast cell granule Schaffer collateral - CA1 synapse glutamatergic synapse postsynaptic specialization,
Serglycin
Mammalian protein found in humans
membrane dendrite neuron projection nucleus presynaptic membrane Schaffer collateral - CA1 synapse glutamatergic synapse postsynaptic density membrane
Metabotropic glutamate receptor 1
Metabotropic_glutamate_receptor_1
American neuroscientist
channels in the active zone shapes neurotransmitter release from Schaffer collateral synapses". The Journal of Neuroscience. 32 (50): 18157–18176. doi:10
Annalisa_Scimemi
Mammalian protein found in humans
complex presynaptic membrane cell projection postsynaptic membrane Schaffer collateral - CA1 synapse presynaptic active zone cytoplasmic component postsynaptic
Catenin_beta-1
Type of dendrite found at the apex of cortical pyramidal cell pathways
distant to most distant from the soma of the neuron. CA3 projects Schaffer collaterals to apical dendrites in CA1. Individual pyramidal cells in the CA3
Apical_dendrite
Protein-coding gene in the species Homo sapiens
intermediate filament cytoplasm postsynaptic density cytoskeleton Schaffer collateral - CA1 synapse postsynaptic intermediate filament cytoskeleton Biological
NEFH
Chemical compound
disinhibiting acetylcholine release, and increasing hippocampal CA3-schaffer collateral mediated glutamate release onto CA1 pyramidal neurons. In a murine
Linopirdine
Protein-coding gene in the species Homo sapiens
plasma membrane postsynaptic density SNARE complex myelin sheath Schaffer collateral - CA1 synapse glutamatergic synapse Biological process neurotransmitter
Synapsin_2
Protein-coding gene in the species Homo sapiens
extracellular exosome plasma membrane intracellular anatomical structure Schaffer collateral - CA1 synapse integral component of synaptic membrane Biological
PTPRA
Protein-coding gene in humans
cytoplasm perinuclear endoplasmic reticulum glial cell projection Schaffer collateral - CA1 synapse glutamatergic synapse postsynaptic density, intracellular
FYN
Protein-coding gene in the species Homo sapiens
endoplasmic reticulum neuron projection dendritic shaft receptor complex Schaffer collateral - CA1 synapse glutamatergic synapse integral component of postsynaptic
EPH_receptor_A4
Mammalian protein found in Homo sapiens
membrane stress fiber postsynaptic density protein-containing complex Schaffer collateral - CA1 synapse glutamatergic synapse Biological process positive regulation
Protein_kinase_C_zeta_type
Cell surface receptor found in humans
component of plasma membrane intracellular anatomical structure synapse Schaffer collateral - CA1 synapse glutamatergic synapse Biological process cellular response
Adenosine_A2B_receptor
Topics referred to by the same term
interacting with sound waves in transparent crystals or glasses Schaffer collaterals, given off by CA3 pyramidal cells in the hippocampus Shafer Commission
Schaefer_(disambiguation)
Protein found in humans
nucleoplasm nucleus cytoplasm cytosol microtubule neuron projection Schaffer collateral - CA1 synapse postsynapse glutamatergic synapse Biological process
Cyclin-dependent_kinase_5
Protein-coding gene in the species Homo sapiens
protein-coupled receptor heterodimeric complex presynaptic membrane presynapse Schaffer collateral - CA1 synapse GABA-ergic synapse Biological process gamma-aminobutyric
GABBR1
Protein-coding gene in the species Homo sapiens
membrane dendritic spine slit diaphragm cell projection synapse Schaffer collateral - CA1 synapse glutamatergic synapse Biological process multicellular
PPP3CA
"Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses". Proceedings of the National Academy of Sciences. 115 (21):
Optogenetic methods to record cellular activity
Optogenetic_methods_to_record_cellular_activity
Action potential generated in the dendrite of a neuron
through the apical dendritic tuft (500-750 μm from soma) and the Schaffer-collateral (SC) through the basal and apical dendrites (250-500 μm from soma)
Dendritic_spike
Protein found in humans
membrane membrane T-tubule plasma membrane endoplasmic reticulum Schaffer collateral - CA1 synapse integral component of postsynaptic density membrane
Zinc_transporter_1
Human protein and coding gene
presynapse dendritic spine postsynaptic density cytoplasmic vesicle Schaffer collateral - CA1 synapse glutamatergic synapse Biological process regulation
DVL1
Neurotransmitters that are released at the synapse
Thomas G. (2013). "Developmental Refinement of Vesicle Cycling at Schaffer Collateral Synapses". Neuron. 77 (6): 1109–1121. doi:10.1016/j.neuron.2013.01
Synaptic_vesicle
Protein-coding gene in the species Homo sapiens
protein binding Cellular component cytosol membrane plasma membrane Schaffer collateral - CA1 synapse glutamatergic synapse postsynaptic density, intracellular
ABR, RhoGEF and GTPase activating protein
ABR,_RhoGEF_and_GTPase_activating_protein
Protein-coding gene in the species Homo sapiens
glutamate receptor complex postsynaptic density cytosol plasma membrane Schaffer collateral - CA1 synapse glutamatergic synapse neuron spine Biological process
SHANK1
Protein-coding gene in the species Homo sapiens
region cytosol plasma membrane intercellular bridge Flemming body Schaffer collateral - CA1 synapse glutamatergic synapse anchored component of presynaptic
Netrin_G2
Thomas G. (2013). "Developmental Refinement of Vesicle Cycling at Schaffer Collateral Synapses". Neuron. 77 (6): 1109–1121. doi:10.1016/j.neuron.2013.01
Synapto-pHluorin
Mammalian protein found in humans
extracellular exosome postsynaptic density membrane presynaptic membrane Schaffer collateral - CA1 synapse postsynaptic density membrane Biological process phospholipase
Metabotropic glutamate receptor 5
Metabotropic_glutamate_receptor_5
Protein-coding gene in the species Homo sapiens
component cytoplasm terminal bouton extracellular exosome cytoskeleton Schaffer collateral - CA1 synapse presynapse postsynapse glutamatergic synapse Biological
PFN2
Mammalian protein found in Homo sapiens
discdkac nucleus actin cytoskeleton stress fiber spine apparatus Schaffer collateral - CA1 synapse glutamatergic synapse Biological process positive regulation
SYNPO
Protein-coding gene in the species Homo sapiens
membrane ciliary base cAMP-dependent protein kinase complex synapse Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
PRKAR1B
Protein-coding gene in the species Homo sapiens
inhibitory synapse dendrite presynaptic membrane cell surface axon Schaffer collateral - CA1 synapse glutamatergic synapse GABA-ergic synapse integral component
NPTN
Protein-coding gene in the species Homo sapiens
activity Cellular component cytoplasm nucleus nucleoplasm cytosol Schaffer collateral - CA1 synapse postsynaptic endocytic zone glutamatergic synapse Biological
RNF216
Protein-coding gene in the species Homo sapiens
cell cortex cytoskeleton membrane focal adhesion cytoplasm cytosol Schaffer collateral - CA1 synapse soma Biological process protein targeting G protein-coupled
AKAP12
Protein-coding gene in the species Homo sapiens
projection branch point dendritic spine cytoplasm presynapse nucleoplasm Schaffer collateral - CA1 synapse glutamatergic synapse postsynaptic density, intracellular
BAIAP2
Protein-coding gene in humans
plasma membrane integral component of plasma membrane soma dendrite Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
EPHA7
Protein-coding gene in the species Homo sapiens
protein binding Cellular component plasma membrane synaptic vesicle Schaffer collateral - CA1 synapse cytoplasm dendritic spine synapse Biological process
APBA2
Protein-coding gene in the species Homo sapiens
membrane cytosol hippocampal mossy fiber to CA3 synapse synapse Schaffer collateral - CA1 synapse presynapse glutamatergic synapse postsynaptic density
SH3GL1
Protein-coding gene in the species Homo sapiens
net collagen-containing extracellular matrix extracellular matrix Schaffer collateral - CA1 synapse glutamatergic synapse Biological process negative regulation
Tenascin-R
Protein-coding gene in the species Homo sapiens
nucleus guanylate cyclase complex, soluble postsynaptic density Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
ADCY1
Protein-coding gene in the species Homo sapiens
postsynapse endomembrane system presynaptic active zone membrane Schaffer collateral - CA1 synapse glutamatergic synapse Biological process synaptic vesicle
Syntaxin_3
Protein-coding gene in the species Homo sapiens
membrane membrane plasma membrane guanylate cyclase complex, soluble Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
ADCY8
Protein-coding gene in the species Homo sapiens
membrane cytoplasmic vesicle cytosol cytoplasm neuromuscular junction Schaffer collateral - CA1 synapse extrinsic component of presynaptic membrane presynaptic
STXBP5
Mammalian protein found in Homo sapiens
activity Cellular component cytoplasm nucleus cytosol plasma membrane Schaffer collateral - CA1 synapse glutamatergic synapse Biological process platelet activation
DGKB
Protein-coding gene in the species Homo sapiens
presynapse synaptic vesicle membrane photoreceptor ribbon synapse Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse glutamatergic
SH3GL2
InterPro Family
axons of the CA3 pyramidal cells project into CA1 cells through the Schaffer collaterals. The long-term potentiation (LTP) may induce in either of these pathways
Trk_receptor
Protein-coding gene in humans
compartment dendrite excitatory synapse postsynaptic density membrane Schaffer collateral - CA1 synapse glutamatergic synapse integral component of postsynaptic
CACNG3
Protein-coding gene in the species Homo sapiens
of plasma membrane membrane extracellular region plasma membrane Schaffer collateral - CA1 synapse glutamatergic synapse anchored component of presynaptic
Netrin_G1
Protein-coding gene in the species Homo sapiens
dendritic spine plasma membrane synapse excitatory synapse membrane Schaffer collateral - CA1 synapse glutamatergic synapse integral component of postsynaptic
LRRC4
Protein-coding gene in the species Homo sapiens
vesicle membrane dendritic spine dendritic shaft cytoplasmic vesicle Schaffer collateral - CA1 synapse presynapse postsynapse glutamatergic synapse Biological
GIPC1
Protein-coding gene in the species Homo sapiens
region of cytoplasm integral component of synaptic vesicle membrane Schaffer collateral - CA1 synapse postsynapse integral component of presynaptic active
SYT11
Governor of Colorado since 2019 (born 1975)
won't accomplish a meaningful reduction in piracy and causes massive collateral damage to the Internet ecosystem." While debating SOPA on the House floor
Jared_Polis
American intelligence officer (born 1971)
February 18, 2025. Retrieved May 22, 2026. Nakashima, Ellen; Strobel, Warren; Schaffer, Aaron (April 8, 2025). "Gabbard sets up DOGE-style team to cut costs,
Aaron_Lukas
was popularized". The Consumers Union Report on Licit and Illicit Drugs. Schaffer Drug Library. Retrieved 1 June 2010. Woods, Crawford (July 23, 1972). Fear
History and culture of substituted amphetamines
History_and_culture_of_substituted_amphetamines
SCHAFFER COLLATERAL
SCHAFFER COLLATERAL
Surname or Lastname
English
English : variant of Chaffee.
Boy/Male
German
Steward.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : descriptive nickname from a derivative of Old French chauf ‘bald’ (Latin calvus). Compare Cave.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : nickname for a greedy person, from Old French saffre ‘glutton’.South German : topographic name for someone living in a damp depression.Jewish (Ashkenazic) : variant of Safir.
Boy/Male
German
Steward.
Surname or Lastname
English (Dorset)
English (Dorset) : variant spelling of Chaffee. In the U.K. this is the usual spelling of the surname.
Surname or Lastname
English
English : topographic name for someone who lived by the seashore, Middle English schore.English : topographic name for someone who lived on or by a bank or steep slope, Old English scora. There are minor places named with this word in Lancashire and West Yorkshire, and the surname may also be a habitational name from these.Americanized spelling of Ashkenazic Jewish S(c)hor(r) or Szor, variants of Schauer.
Boy/Male
Arabic
Kind
Surname or Lastname
English, Portuguese, Galician, Spanish, Catalan, and French
English, Portuguese, Galician, Spanish, Catalan, and French : occupational name for a shepherd, Anglo-Norman French pastre (oblique case pastour), Portuguese, Galician, Spanish, Catalan, pastor ‘shepherd’, from Latin pastor, an agent derivative of pascere ‘to graze’. The religious sense of a spiritual leader was rare in the Middle Ages, and insofar as it occurs at all it seems always to be a conscious metaphor; it is unlikely, therefore, that this sense lies behind any examples of the surname.German and Dutch : humanistic name, a Latinized form of various vernacular names meaning ‘shepherd’, for example Hirt or Schäfer (see Schafer).Americanized spelling of Hungarian Pásztor, an occupational name from pásztor ‘shepherd’.
Boy/Male
Arabic, Muslim
Messenger
Surname or Lastname
English
English : variant of Chaffee.
Boy/Male
Muslim
Messenger
Boy/Male
German
Steward; Shepherd
SCHAFFER COLLATERAL
SCHAFFER COLLATERAL
Boy/Male
Indian, Punjabi, Sikh
Honour of the People
Boy/Male
Hindu, Indian, Sanskrit
Seller of Milk; One who Brings the Milk; A Hermit who was Taught by Indra the Art of Preparing Rice for Offering to the Gods
Boy/Male
Celtic American Gaelic Irish
White.
Girl/Female
Tamil
Phullara | பà¯à®²à¯à®²à®¾à®°à®¾
Goddess Durga
Girl/Female
Hindu
Discipline
Girl/Female
Hindu
Emerald, It is very precious natural stone in the world
Girl/Female
English French
Medieval male name adopted as a feminine name.
Male
Greek
(Υπάτιος) Variant form of Greek Hypatos, HYPATIOS means "most high, supreme."Â
Girl/Female
Arabic, Muslim
Iron
Girl/Female
Indian
Pleasant Touch
SCHAFFER COLLATERAL
SCHAFFER COLLATERAL
SCHAFFER COLLATERAL
SCHAFFER COLLATERAL
SCHAFFER COLLATERAL
n.
A scoffer; a railer; a mocker.
p. pr. & vb. n.
of Chamfer
n.
Bargaining; merchandise.
n.
A chamfer.
v. i.
To chaffer; to stickle for small advantages in buying and selling; to haggle.
v. t.
To make a chamfer on.
n.
One who chaffs.
p. p. & a.
Sunk into a chamfer; as, a countersunk bolt.
imp. & p. p.
of Chamfer
n.
A hobbler; one who limps; a shuffer.
p. pr. & vb. n.
of Chaffer
v. t.
To exchange; to bandy, as words.
n.
To treat or dispute about a purchase; to bargain; to haggle or higgle; to negotiate.
n.
To talk much and idly; to chatter.
v. t.
To buy or sell; to trade in.
imp. & p. p.
of Chaffer
n.
A kind of beetle; the cockchafer. The name is also applied to other species; as, the rose chafer.
v. t.
To ask the price of; to bid, bargain, or chaffer for.
n.
A spurner or contemner; a despiser; a scoffer.
n.
One who chaffers; a bargainer.