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Measurement made on an electrocardiogram
The QT interval is a measurement made on an electrocardiogram used to assess some of the electrical properties of the heart. It is calculated as the time
QT_interval
Medical condition
LQTS can be diagnosed using an electrocardiogram (EKG) if a corrected QT interval of greater than 450–500 milliseconds is found, but clinical findings
Long_QT_syndrome
Changes to heartbeat caused by a drug
the length of phase 3 myocardial repolarization, resulting in QT prolongation. A QT interval is a value that is measured on an electrocardiogram. Measurements
Drug-induced_QT_prolongation
QT interval variability (QTV) refers to the physiological phenomenon of beat-to-beat fluctuations in QT interval of electrocardiograms. Increased QTV appears
QT_interval_variability
Medical condition
characteristic feature seen on an electrocardiogram (ECG) – a shortening of the QT interval. It is caused by mutations in genes encoding ion channels that shorten
Short_QT_syndrome
SSRI antidepressant
dose-dependent QT interval prolongation, which is a measure of how rapidly the heart muscle repolarizes after each heartbeat. Prolongation of the QT interval is a
Escitalopram
Type of abnormal heart rhythm
the QT interval can increase a person's risk of developing this abnormal heart rhythm, occurring in between 1% and 10% of patients who receive QT-prolonging
Torsades_de_pointes
Examination of the heart's electrical activity
This analysis calculates features such as the PR interval, QT interval, corrected QT (QTc) interval, PR axis, QRS axis, rhythm and more. The results from
Electrocardiography
Antifungal medication
QT interval prolongation, which may lead to serious cardiac arrhythmias. Thus, it is used with caution in patients with risk factors for prolonged QT
Fluconazole
Rare autosomal dominant genetic disorder
characterised by an abnormality seen on an electrocardiogram (a long QT interval) and a tendency to abnormal heart rhythms, physical characteristics including
Andersen–Tawil_syndrome
SSRI antidepressant
taken alongside other drugs that prolong the QT interval, or by those with a susceptibility to long QT syndrome, there is a small risk of potentially
Fluoxetine
Topics referred to by the same term
Look up QT, Qt, qt, or q.t. in Wiktionary, the free dictionary. QT or Qt may refer to: Qt Group, a Finnish software developer QT Hotels & Resorts, an Australasian
QT
Abnormally fast rhythm of the heart's ventricles
ECG as a prolongation of the QT interval. QT prolongation may be congenital or acquired. Congenital problems include long QT syndrome and catecholaminergic
Ventricular_tachycardia
Antimalarial medication
with short-term use of Hydroxychloroquine include low blood sugar and QT interval prolongation. Idiosyncratic hypersensitivity reactions have occurred
Hydroxychloroquine
High calcium (Ca2+) level in the blood serum
confirmed after a week. Specific changes, such as a shortened QT interval and prolonged PR interval, may be seen on an electrocardiogram (ECG). Treatment may
Hypercalcaemia
Medication to prevent nausea and vomiting
people taking other medicines that prolong the QT interval, as well as in people with congenital long QT syndrome, congestive heart failure, and/or bradyarrhythmias
Ondansetron
Medical condition
phase of the cardiac action potential, and therefore the length of the QT interval. The LQT3 subtype of Romano–Ward syndrome is caused by variants in the
Romano–Ward_syndrome
Online medication database
has a special focus on drugs that prolong the QT interval on the ECG and thereby carry the risk of QT prolongation and torsades de pointes (TdP) ventricular
CredibleMeds
Teaching aid in cardiac physiology
Cardiac diastole ECG The EKG complex. P=P wave, PR=PR interval, QRS=QRS complex, QT=QT interval, ST=ST segment, T=T wave Wiggers with jugular venous waveform
Wiggers_diagram
Class of medications
prolonged QT interval in the heart, which can be dangerous for patients with heart disease or those taking other drugs that prolong the QT interval. Lurasidone
Antipsychotic
Electrocardiogram waveform representing repolarization of the heart's ventricles
or vulnerable period. The T wave contains more information than the QT interval. The T wave can be described by its symmetry, skewness, slope of ascending
T_wave
Antibiotic
absorption of moxifloxacin. Drugs that prolong the QT interval (e.g., pimozide) may have an additive effect on QT prolongation and lead to increased risk of ventricular
Moxifloxacin
Chemical compound
lengthening of the QT interval. Therefore, it should not be taken by people taking other medications that affect the QT interval (such as amiodarone)
Vardenafil
Cardiac rhythm
of 1:1. Normal P wave axis (0 to +75 degrees) Normal PR interval, QRS complex and QT interval. QRS complex positive in leads I, II, aVF and V3–V6, and
Sinus_rhythm
Drug used to treat angina
QT interval in some patients and the FDA label contains a warning for doctors to beware of this effect in their patients. The drug's effect on the QT
Ranolazine
Chemical compound
including people with a known history of QT prolongation and people taking medications known to prolong the QT interval. The most common side effects of solifenacin
Solifenacin
Use of arsenic trioxide as a medication
channel and altering calcium channel activity, which can lead to prolonged QT intervals and arrhythmias, sometimes causing fatal cardiac events. The broad range
Arsenic_trioxide_(medication)
Genetic kidney disorder
paralysis have been reported. Abnormal heart rhythms and a prolonged QT interval can be detected on electrocardiogram and cases of sudden cardiac death
Gitelman_syndrome
Medical condition
loss from birth, affecting both ears. Those affected have a prolonged QT interval on an electrocardiogram and are at risk of abnormal heart rhythms (arrhythmias)
Jervell and Lange-Nielsen syndrome
Jervell_and_Lange-Nielsen_syndrome
Aspect of heart function
The ECG complex. P=P wave, PR=PR interval, QRS=QRS complex, QT=QT interval, ST=ST segment, T=T wave
Cardiac_conduction_system
Antidopaminergic drug
(November 1994). "Droperidol causes a dose-dependent prolongation of the QT interval". Anesthesia and Analgesia. 79 (5): 983–986. doi:10.1213/00000539-199411000-00028
Droperidol
evidence supporting this contention consists mostly of minor changes in QT interval in a small number of astronauts after long-duration space flight. Concurrent
Cardiac rhythm problems during spaceflight
Cardiac_rhythm_problems_during_spaceflight
Antiarrythmic medication
drug causes increased action potential duration, as well as a prolonged QT interval. As of 2019, its IV formulation is no longer being manufactured for use
Quinidine
Poisoning of heart electrophysiology or muscle
such as thioridazine which can prolong QT interval Antibiotics such as erythromycin and levofloxacin due to QT prolongation Heavy metals such as lead
Cardiotoxicity
Antihistamine medication
antihistamines, as levocetirizine does not significantly prolong the QT interval in healthy individuals. However, some people may still experience some
Levocetirizine
Antibiotic
prolong the QT interval in some people, especially the elderly, and levofloxacin should not be used for people with a family history of long QT syndrome
Levofloxacin
Endocrine disease
irregularities in the normal heart beat (specifically prolongation of the QT interval), as well as spasm of the upper part of the airways or the smaller airways
Hypoparathyroidism
Peripheral D2 receptor antagonist
death (by 70%) most likely through its prolonging effect of the cardiac QT interval and ventricular arrhythmias. The cause is thought to be blockade of hERG
Domperidone
Medical condition
electrocardiogram (ECG). ECG changes may include QRS widening and a prolonged QT interval. Initial treatment of exposure involves removing contaminated clothing
Hydrofluoric_acid_burn
Inflammation of the heart muscle
The presence of Q waves, a widened QRS complex, prolongation of the QT interval, high degree AV nodal blockade, and ventricular tachyarrhythmias are
Myocarditis
Branch of medicine dealing with the heart
lengthening of the QT interval—drug-induced QT prolongation—and an EKG may be warranted before starting the medication to ensure a normal QT interval, but this
Outline_of_cardiology
Chemical compound
decreased likelihood that electrical re-entry will occur. Increasing the time interval between stimulus to atrium and/or atrium to bundle of his in action potential
Budiodarone
Perceived cardiac abnormality in which one's heartbeat can be felt
the etiology of the palpitations, and a prolonged QT interval may indicate the presence of the long QT syndrome. Laboratory studies should be limited initially
Palpitations
Illness from ingesting arsenic
portal hypertension). There may also be cardiovascular effects such as QT interval prolongation, tachycardia or heart failure which may result in death
Arsenic_poisoning
Sudden increase in adrenaline and noradrenaline in the blood
use was formerly discouraged because of their potential to prolong the QT interval; however, more recent research performed since 2019 has revealed that
Adrenergic_storm
Antihistamine medication
plasma levels of fexofenadine, but this increase does not influence the QT interval. The reason for this effect is likely due to transport-related effects
Fexofenadine
Class of antibacterial drugs, subgroup of quinolones
Fluoroquinolones prolong the heart's QT interval by blocking voltage-gated potassium channels. Prolongation of the QT interval can lead to torsades de pointes
Quinolone_antibiotic
Medical condition
in excitotoxicity. Alterations in ECG (in particular an increase in QT interval) and EEG abnormalities (including abnormal quantified EEG) may occur
Alcohol_withdrawal_syndrome
Heart rate exceeding normal resting rate
due to its appearance on an EKG), which tends to result from a long QT interval. Both of these rhythms normally last for only a few seconds to minutes
Tachycardia
UK, US Neurotoxicity Clobutinol 2007 Germany Ventricular arrhythmias, QT-interval prolongation Cloforex 1969 Germany Cardiovascular toxicity Clomacran
List_of_withdrawn_drugs
Antiarrhythmic medication
polymorphic ventricular tachycardia as it is associated with a prolonged QT interval which will be made worse with anti-arrhythmic drugs. Individuals who
Amiodarone
Atypical antipsychotic medication
Rare (<1% incidence) adverse effects Prolonged QT interval (had an odds ratio for prolonging the QT interval over placebo of 0.17) Sudden cardiac death Syncope
Quetiapine
Physiological state of dormant inactivity in order to pass the winter season
the reduced relaxation (QT) interval of small hibernators was the same for the three bear species. They also found the QT interval changed for both typical
Hibernation
Chemical compound
affect QT interval and possibly predispose those using it to cardiac arrhythmias. However, itopride does not have any adverse effect on the QT interval. Later
Itopride
Flushing Rare (<0.1%) adverse effects include: Urinary retention Prolonged QT interval Torsades de Pointes Ataxia Breast enlargement or engorgement Lactation
List of adverse effects of trazodone
List_of_adverse_effects_of_trazodone
Critical potential value
care must be exercised when QT intervals are prolonged in such patients: arrhythmias as a result of prolonged QT intervals include the potentially fatal
Threshold_potential
Pharmaceutical drug
drugs that both prolong the QT interval and are metabolized by CYP2D6 (e.g., thioridazine, pimozide); effects on QT interval may be increased Concomitant
Dextromethorphan/quinidine
Enzymes that block actions of protein kinases
fluid retention, pancreatitis and cardiotoxicity (mostly QT interval prolongation). QT interval prolongation and electrolyte anomalies ++ + + D D 29 October
Protein_kinase_inhibitor
Immunosuppressive drug
Neoplastic disease, such as: Skin cancer Lung cancer Oliguria Pregnancy QT interval prolongation Sunlight (UV) exposure Grapefruit juice Occlusive dressing
Tacrolimus
Science of elucidating, diagnosing, and treating the electrical activities of the heart
refractory period Pacemaker potential Electrocardiography P wave PR interval QRS complex QT interval ST segment T wave U wave Hexaxial reference system Chamber
Cardiac_electrophysiology
Group of autoimmune diseases resulting in abnormal growth of connective tissue
uncommonly hepatotoxicity, heart dysfunction/failure, myocardial infarction, QT interval prolongation, renal failure and hypersensitivity. Imatinib As above PO
Scleroderma
Heart rhythm medication
myocyte repolarization. Class III agents have the potential to prolong the QT interval of the EKG, and may be proarrhythmic (more associated with development
Antiarrhythmic_agent
Typical antipsychotic medication
both of which may be permanent. Neuroleptic malignant syndrome and QT interval prolongation may occur, the latter particularly with IV administration
Haloperidol
Medication used for opioid withdrawal
the QT interval, which can result in a severe interaction (torsade de pointes) when combined with other drugs that also prolong the QT interval. Patient-specific
Lofexidine
Chemical compound
1–10% of people. Anaphylactic reactions are rare. The drug prolongs the QT interval. Miconazole is partly absorbed in the intestinal tract when used orally
Miconazole
Chemical compound with formula MgSO4
consideration of intravenous magnesium sulfate when secondary to a long QT interval. Blitz M, Blitz S, Hughes R, Diner B, Beasley R, Knopp J, Rowe BH (2005)
Magnesium_sulfate
Sudden temporary weakening of the heart muscle
pain, shortness of breath, ST-segment elevation, T-wave inversion or QT-interval prolongation on ECG. Cardiac enzymes are usually negative and are moderate
Takotsubo_cardiomyopathy
Opioid analgesic
depression. Abnormal heart rhythms may also occur due to a prolonged QT interval. The number of deaths in the United States involving methadone poisoning
Methadone
Low calcium levels in one's blood serum
include the following: Intermittent QT prolongation, or intermittent prolongation of the QTc (corrected QT interval) on the ECG (electrocardiogram) is
Hypocalcemia
Medication used to treat ADHD
there was a slight but significant increase in QTc interval with higher atomoxetine concentrations. QT prolongation has been reported with atomoxetine at
Atomoxetine
Antibiotic
conditions are at particular risk, such as those with abnormalities in the QT interval, low blood levels of potassium or magnesium, a slower than normal heart
Azithromycin
Medication
Severe hepatic impairment QTc Bazett interval ≥500 ms, or use with drugs or herbal supplements that prolong QT interval or increase risk of torsades de points
Dronedarone
Australian exoneree (born 1967)
Long QT syndrome, a disorder that affects repolarisation (relaxing) of the heart after a heartbeat, giving rise to an abnormally lengthy QT interval. It
Kathleen_Folbigg
Plant-derived medication
people taking digoxin include increased PR interval (due to decreased AV conduction) and a shortened QT interval. Also, the T wave may be inverted and accompanied
Digoxin
Antibiotic medication
administered to people using these drugs, or drugs that also prolong the QT interval. Other examples include terfenadine (Seldane, Seldane-D), astemizole
Erythromycin
vomiting, and diarrhea (especially at higher doses) Prolonged cardiac QT interval (especially erythromycin) Hearing loss (especially at higher doses) Jaundice
List_of_antibiotics
SSRI drug and metabolite of fluoxetine
blocking the KvLQT1 protein, which is responsible for the management of the QT interval. This is the time it takes for the heart to contract and recover. Due
Seproxetine
Medical condition
reflecting current outcomes. Since then, systematic screening for prolonged QT interval in infants born with syndactyly has enabled earlier diagnosis, and early
Timothy_syndrome
Medication
sotalol prolongs the QT interval, the FDA recommends against using it in conjunction with other medications that prolong the QT interval. Studies have found
Sotalol
Medical diagnostic method
primarily on the monitoring of arrhythmia, myocardial infarction, and QT interval monitoring. It is categorized into one of three classes using a rating
Cardiac_monitoring
pectoris Myocardial ischaemia Pancreatitis Diabetic ketoacidosis Prolonged QT interval (less common than with most other atypical antipsychotic drugs) Speech
List of adverse effects of aripiprazole
List_of_adverse_effects_of_aripiprazole
Mammalian protein found in humans
containing channels are blocked by amiodarone, and it does prolong the QT interval, but its multiple other antiarrhythmic effects prevent this from causing
KCNH2
Electrocardiogram waveform representing atrial contraction
disease states such as cardiac ischaemia. Electrocardiography PR interval QRS complex QT interval ST segment T wave U wave Longmore, Murray (2004). Oxford Handbook
P_wave_(electrocardiography)
Typical antipsychotic medication
Hypoparathyroidism Prostatic hypertrophy Very rarely, elongation of the QT interval, due to hERG blockade, may occur, increasing the risk of potentially
Chlorpromazine
Extreme manifestation of hypothyroidism
Polymorphic ventricular tachycardia (torsades de pointes) Prolonged QT interval Respiratory Hypoxia Hypercapnia Hyperventilation Myxedema of the larynx
Myxedema_coma
Combination of two antibiotic drugs
(increased risk of ventricular arrhythmias) and dofetilide (increased risk of QT interval prolongation) Antibacterials like dapsone (increases plasma levels of
Trimethoprim/sulfamethoxazole
Antiarrhythmic medication
potential. There is a dose-dependent increase in the QT interval and the corrected QT interval (QTc). Because of this, many practitioners will initiate
Dofetilide
Chemical compound
electrical rhythms of the heart (specifically cardiac arrhythmia caused by QT interval prolongation) and has been withdrawn from most markets worldwide. Terfenadine
Terfenadine
Antidepressant medication
(heart attack). Concomitant administration of drugs that prolong the QT interval or that are inhibitors of CYP3A4 may increase the risk of cardiac arrhythmia
Trazodone
Type of diet
diet. Observations in 17 patients and the role of the prolonged QT interval". Circulation. 60 (6): 1401–1412. doi:10.1161/01.CIR.60.6.1401. ISSN 0009-7322
Protein-sparing modified fast (diet)
Protein-sparing_modified_fast_(diet)
Harmful, unintended response to medications
this is multiple medications administered concurrently that prolong the QT interval, such as antiarrhythmics like sotalol and some macrolide antibiotics
Adverse_drug_reaction
adverse effects of risperidone, occurring less than 1%, include: Prolonged QT interval Sudden cardiac death Syncope (oral, up to 1%; IM, up to 2%) Diabetic
List of adverse effects of risperidone
List_of_adverse_effects_of_risperidone
Abnormal depolarizations of cardiac myocytes
arrhythmias. EADs can be triggered by hypokalemia and drugs that prolong the QT interval, including class Ia and III antiarrhythmic agents, as well as catecholamines
Afterdepolarization
Life-threatening response to infection
enteral feeding. However, these agents may precipitate prolongation of the QT interval and consequently provoke a ventricular arrhythmia such as torsades de
Sepsis
Diet with very or extremely low daily food energy consumption
diet. Observations in 17 patients and the role of the prolonged QT interval". Circulation. 60 (6): 1401–12. doi:10.1161/01.cir.60.6.1401. PMID 498466
Very-low-calorie_diet
Abnormal kidney structure or gradual loss of kidney function
and a severe electrolyte imbalance: hyperkalemia (7.4 mmol/L) with hypocalcemia (1.6 mmol/L). The T-waves are peaked and the QT interval is prolonged.
Chronic_kidney_disease
Chemical compound
patients with a previous history of heart disease. It may also cause QT interval prolongation. Probucol was originally developed as an industrial antioxidant
Probucol
Antibiotic medication
Clarithromycin can lead to a prolonged QT interval. In patients with long QT syndrome, cardiac disease, or patients taking other QT-prolonging medications, this
Clarithromycin
Toxicity from too much ethylene glycol
concentrations in the blood, overactive muscle reflexes, muscle spasms, QT interval prolongation, and congestive heart failure may occur. If untreated, death
Ethylene_glycol_poisoning
Excess potassium in the blood
seen in the following progression: peaked T wave, shortened QT interval, lengthened PR interval, increased QRS duration, and eventually absence of the P
Hyperkalemia
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