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PRDM9

  • PRDM9

    • Protein-coding gene in humans

    zinc finger protein 9 is a protein that in humans is encoded by the PRDM9 gene. PRDM9 is responsible for positioning recombination hotspots during meiosis

    PRDM9

    PRDM9

    PRDM9

  • Homologous recombination

    • Genetic recombination between identical or highly similar strands of genetic material

    at which recombination occurs are determined by the binding locations of PRDM9, a protein which recognizes a specific sequence motif by its zinc finger

    Homologous recombination

    Homologous recombination

    Homologous_recombination

  • ATR-X syndrome

    • Medical condition

    and pericentromeric regions. A couple of these genes include: PRDM9 and 2-BHMT2. PRDM9 encodes for a histone H3 lysine-4 trimethyltransferase, which is

    ATR-X syndrome

    ATR-X syndrome

    ATR-X_syndrome

  • Recombination hotspot

    • Genome region with relatively high rate of recombination

    2 to 16.7-Mb region of mouse chromosome 17, which contains the PRDM9 gene. The PRDM9 gene encodes a histone methyltransferase in the Dsbc1 region, providing

    Recombination hotspot

    Recombination_hotspot

  • Homeobox

    • DNA pattern affecting anatomy development

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Homeobox

    Homeobox

    Homeobox

  • FOXP2

    • Transcription factor gene of the forkhead box family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    FOXP2

    FOXP2

    FOXP2

  • FOXO3

    • Protein-coding gene in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    FOXO3

    FOXO3

    FOXO3

  • SMAD (protein)

    • Family of proteins

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    SMAD (protein)

    SMAD_(protein)

  • Philip Awadalla

    • Canadian geneticist (born 1969)

    discovered the relationship of a histone methylating factor encoded by the gene PRDM9 and child-hood acute lymphoblastic leukemia. Research by Awadalla (with

    Philip Awadalla

    Philip_Awadalla

  • NFAT

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    NFAT

    NFAT

  • Basic helix–loop–helix

    • Protein structural motif

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Basic helix–loop–helix

    Basic helix–loop–helix

    Basic_helix–loop–helix

  • Receptor (biochemistry)

    • Protein molecule receiving signals for a cell

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • Peroxisome proliferator-activated receptor

    • Group of nuclear receptor proteins

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Peroxisome proliferator-activated receptor

    Peroxisome proliferator-activated receptor

    Peroxisome_proliferator-activated_receptor

  • NFE2L2

    • Human protein and coding gene

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    NFE2L2

    NFE2L2

    NFE2L2

  • HIF1A

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    HIF1A

    HIF1A

    HIF1A

  • FOX proteins

    • Family of transcription factors involved in anatomical development

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    FOX proteins

    FOX proteins

    FOX_proteins

  • TP63

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    TP63

    TP63

    TP63

  • P53

    • Mammalian protein found in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    P53

    P53

    P53

  • BAZ1B

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    BAZ1B

    BAZ1B

    BAZ1B

  • Progesterone receptor A

    • Isoform of the progesterone receptor

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Progesterone receptor A

    Progesterone receptor A

    Progesterone_receptor_A

  • Rho factor

    • Prokaryotic protein

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Rho factor

    Rho factor

    Rho_factor

  • IRF9

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    IRF9

    IRF9

    IRF9

  • CREB

    • Class of proteins

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    CREB

    CREB

    CREB

  • NF-κB

    • Family of transcription factor protein complexes

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    NF-κB

    NF-κB

    NF-κB

  • Steroid hormone receptor

    • Group of protein families

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Steroid hormone receptor

    Steroid_hormone_receptor

  • Sex-determining region Y protein

    • Protein that initiates male sex determination in therian mammals

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • Myc

    • Family of regulator genes

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Myc

    Myc

  • Androgen receptor

    • Mammalian protein found in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • Retinoid receptor

    • Nuclear receptors that bind to retinoids

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Retinoid receptor

    Retinoid_receptor

  • Progesterone receptor

    • Cytoplasmic receptor protein found inside cells

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Progesterone receptor

    Progesterone receptor

    Progesterone_receptor

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • IRF4

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    IRF4

    IRF4

    IRF4

  • HES1

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    HES1

    HES1

    HES1

  • List of human transcription factors

    • specific TF according to literature or domain structure – No motif [740] PRDM9 ENSG00000164256 C2H2 ZF Known motif – High-throughput in vitro [741]

    List of human transcription factors

    List_of_human_transcription_factors

  • AP-1 transcription factor

    • Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    AP-1 transcription factor

    AP-1 transcription factor

    AP-1_transcription_factor

  • Transcription factor

    • Protein that regulates the rate of DNA transcription

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Transcription factor

    Transcription factor

    Transcription_factor

  • Gil McVean

    • British statistical geneticist (born 1973)

    statistical method to look at recombination rate which helped to identify PRDM9 as a hotspot positioning gene. In 2014, with Peter Donnelly, McVean co-founded

    Gil McVean

    Gil McVean

    Gil_McVean

  • Peroxisome proliferator-activated receptor delta

    • Nuclear receptor protein found in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Peroxisome proliferator-activated receptor delta

    Peroxisome proliferator-activated receptor delta

    Peroxisome_proliferator-activated_receptor_delta

  • Glucocorticoid receptor

    • Receptor to which cortisol and other glucocorticoids bind

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Glucocorticoid receptor

    Glucocorticoid receptor

    Glucocorticoid_receptor

  • Estrogen receptor

    • Proteins activated by the hormone estrogen

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Estrogen receptor

    Estrogen receptor

    Estrogen_receptor

  • KMT2A

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    KMT2A

    KMT2A

    KMT2A

  • Pax genes

    • Family of transcription factors

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Pax genes

    Pax genes

    Pax_genes

  • CLOCK

    • Human protein and coding gene

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    CLOCK

    CLOCK

    CLOCK

  • PAX6

    • Protein-coding gene in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    PAX6

    PAX6

    PAX6

  • SOX9

    • Transcription factor gene of the SOX family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    SOX9

    SOX9

    SOX9

  • Oct-4

    • Mammalian protein found in Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Oct-4

    Oct-4

    Oct-4

  • CTCF

    • Transcription factor

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    CTCF

    CTCF

    CTCF

  • Heterochromatin protein 1

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Heterochromatin protein 1

    Heterochromatin_protein_1

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • FOXP3

    • Immune response protein

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    FOXP3

    FOXP3

    FOXP3

  • Vitamin D receptor

    • Transcription factor activated by vitamin D

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Vitamin D receptor

    Vitamin D receptor

    Vitamin_D_receptor

  • Zinc finger

    • Small structural protein motif found mostly in transcriptional proteins

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Zinc finger

    Zinc finger

    Zinc_finger

  • Protein c-Fos

    • Mammalian protein found in Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Protein c-Fos

    Protein c-Fos

    Protein_c-Fos

  • Eomesodermin

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Eomesodermin

    Eomesodermin

    Eomesodermin

  • Retinoid X receptor

    • Genes on human chromosome 9

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Retinoid X receptor

    Retinoid_X_receptor

  • Transcription factor Sp3

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Transcription factor Sp3

    Transcription factor Sp3

    Transcription_factor_Sp3

  • FOSB

    • Protein

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    FOSB

    FOSB

    FOSB

  • NFE2L1

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    NFE2L1

    NFE2L1

    NFE2L1

  • Transcription factor II H

    • Protein complex

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Transcription factor II H

    Transcription_factor_II_H

  • Retinoic acid receptor

    • Type of nuclear receptor

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Retinoic acid receptor

    Retinoic acid receptor

    Retinoic_acid_receptor

  • GATA transcription factor

    • Transcription factor

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    GATA transcription factor

    GATA transcription factor

    GATA_transcription_factor

  • ETS transcription factor family

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    ETS transcription factor family

    ETS transcription factor family

    ETS_transcription_factor_family

  • E2F

    • Family of transcription factors

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    E2F

    E2F

  • CCAAT-enhancer-binding proteins

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding_proteins

  • General transcription factor

    • Class of protein transcription factors

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    General transcription factor

    General transcription factor

    General_transcription_factor

  • MADS-box

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    MADS-box

    MADS-box

  • Zbtb7

    • Mammalian protein found in Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Zbtb7

    Zbtb7

  • T-box

    • Genes that affect limb and heart development

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    T-box

    T-box

    T-box

  • Interferon regulatory factors

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Interferon regulatory factors

    Interferon regulatory factors

    Interferon_regulatory_factors

  • Hormone receptor

    • Group of proteins

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Hormone receptor

    Hormone_receptor

  • HOXD13

    • Protein

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    HOXD13

    HOXD13

    HOXD13

  • ARID1B

    • Protein-coding gene in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    ARID1B

    ARID1B

    ARID1B

  • SMAD7

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    SMAD7

    SMAD7

    SMAD7

  • Intracellular receptor

    • Receptors located inside the cell

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Intracellular receptor

    Intracellular_receptor

  • SPI1

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    SPI1

    SPI1

    SPI1

  • Krüppel associated box

    • Protein domain

    Acids That Transform the Ancestral KRAB-A-Related Domain Present in Human PRDM9 into a Canonical Modern KRAB-A Domain". International Journal of Molecular

    Krüppel associated box

    Krüppel associated box

    Krüppel_associated_box

  • Nuclear receptor

    • Protein

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Nuclear receptor

    Nuclear receptor

    Nuclear_receptor

  • Transcription factor II D

    • General transcription factors

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Transcription factor II D

    Transcription_factor_II_D

  • FOXA2

    • Mammalian protein found in Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    FOXA2

    FOXA2

    FOXA2

  • MAF (gene)

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    MAF (gene)

    MAF (gene)

    MAF_(gene)

  • Scleraxis

    • Mammalian protein found in Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Scleraxis

    Scleraxis

  • BCL11A

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    BCL11A

    BCL11A

    BCL11A

  • Small heterodimer partner

    • Protein found in humans

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Small heterodimer partner

    Small heterodimer partner

    Small_heterodimer_partner

  • Hypoxia-inducible factor

    • Protein that responds to low oxygen

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • TOX

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    TOX

    TOX

    TOX

  • List of human protein-coding genes 6

    • Q9NQX0 12769 PRDM7 HGNC:9351; Q9NQW5 12770 PRDM8 HGNC:13993; Q9NQV8 12771 PRDM9 HGNC:13994; Q9NQV7 12772 PRDM10 HGNC:13995; Q9NQV6 12773 PRDM11 HGNC:13996;

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

  • Retinoblastoma-like protein 2

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Retinoblastoma-like protein 2

    Retinoblastoma-like protein 2

    Retinoblastoma-like_protein_2

  • Mineralocorticoid receptor

    • Nuclear receptor that mediates the effects of the mineralocorticoid hormone Aldosterone

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Mineralocorticoid receptor

    Mineralocorticoid receptor

    Mineralocorticoid_receptor

  • Aryl hydrocarbon receptor

    • Vertebrate receptor protein and transcription factor

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Aryl hydrocarbon receptor

    Aryl hydrocarbon receptor

    Aryl_hydrocarbon_receptor

  • NPAS2

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    NPAS2

    NPAS2

    NPAS2

  • Kruppel-like factors

    • Family of zinc finger transcription factors

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Kruppel-like factors

    Kruppel-like_factors

  • Liver X receptor

    • Nuclear receptor

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Liver X receptor

    Liver X receptor

    Liver_X_receptor

  • Sterol regulatory element-binding protein

    • Protein family

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Sterol regulatory element-binding protein

    Sterol regulatory element-binding protein

    Sterol_regulatory_element-binding_protein

  • PRDM16

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    PRDM16

    PRDM16

    PRDM16

  • GTF3A

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    GTF3A

    GTF3A

    GTF3A

  • SOX11

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    SOX11

    SOX11

    SOX11

  • EGR1

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    EGR1

    EGR1

    EGR1

  • Pituitary-specific positive transcription factor 1

    • Protein that controls rate of transcription of GH genes

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    Pituitary-specific positive transcription factor 1

    Pituitary-specific positive transcription factor 1

    Pituitary-specific_positive_transcription_factor_1

  • MYC

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    MYC

    MYC

    MYC

  • NRF1

    • Protein-coding gene in the species Homo sapiens

    KLF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 17 SP 1 2 4 7 8 MTF1 MYT1 OSR1 PRDM9 SALL 1 2 3 4 TSHZ3 WT1 Zbtb7 7A 7B ZBTB 11 16 17 20 21 32 33 40 zinc finger

    NRF1

    NRF1

    NRF1

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Online names & meanings

  • Hasiba |

    • Girl/Female

    Muslim

    Hasiba |

    Highborn, Respected, Noble

  • DRUSILLA

    • Female

    English

    DRUSILLA

    Feminine diminutive form of Roman Latin Drusus, possibly DRUSILLA means "oak; strong." 

  • Haiba

    • Girl/Female

    African, Indian, Swahili

    Haiba

    Charm

  • Said

    • Boy/Male

    Indian

    Said

    Blissful, Auspicious, Happy

  • Saniya

    • Girl/Female

    Hindu

    Saniya

    Moment

  • Rosa

    • Girl/Female

    American, Australian, British, Chinese, Christian, Danish, English, Finnish, French, German, Greek, Hindu, Indian, Irish, Italian, Latin, Marathi, Portuguese, Swedish, Swiss, Tamil

    Rosa

    Rose; Little Rose; Flower Name; Truthful; Kindness; Dew; Famous Guardian; Beautiful

  • Vydic

    • Boy/Male

    Indian

    Vydic

    Follower of Vedas; Reader of Vedas; Protecter of Vedas

  • Irum |

    • Girl/Female

    Muslim

    Irum |

    A garden in heaven

  • POSEIDÔN

    • Male

    Greek

    POSEIDÔN

    (Ποσειδῶν) Greek name probably derived from pósis, POSEIDÔN means "lord, husband." In mythology, this is the name of a god of horses and the sea, known as the "earth-shaker." He is equated with Roman Neptune. 

  • Twilley

    • Surname or Lastname

    English

    Twilley

    English : unexplained.

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