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Protein-coding gene in humans
is a protein that in humans is encoded by the PMEL gene. Its gene product may be referred to as PMEL, silver, ME20, gp100 or Pmel17. MEL is a type I
PMEL_(gene)
Genetic pattern in a dog's coat
Merle is a genetic pattern in a dog's coat and alleles of the PMEL gene. It results in different colors and patterns and can affect any coats. The allele
Merle_(dog_coat)
Scottish breed of cattle
or – more rarely – red. The dun colour is caused by a mutation in the PMEL gene, the same mutation that causes dun and silver dun in Highland cattle.
Belted_Galloway
Medical condition
melanoma antigen recognized by T cells 1 protein), S100, and PMEL (a product of the PMEL gene which is detected using an antibody termed HMB-45.) proteins
Undifferentiated pleomorphic sarcoma
Undifferentiated_pleomorphic_sarcoma
Genetics behind dog coat
at the M locus (the silver locus protein homolog gene or SILV, aka premelanosome protein gene or PMEL) determine whether an animal expresses a merle pattern
Dog_coat_genetics
Scottish breed of cattle
brindle/dun. The coat colours are caused by alleles at the MC1R gene (E locus) and the PMEL or SILV gene (D locus). They have an unusual double coat of hair. On
Highland_cattle
Protein domain
extreme environments, and in the human receptor SorCS2. GPNMB; PKD1; PKD1L1; PMEL; SORCS1; SORCS2; SORCS3 Bycroft M, Bateman A, Clarke J, Hamill SJ, Sandford
PKD_domain
Skin cancer originating in melanocytes
to other forms of cancer. Examples of melanoma specific genes are tyrosinase, MLANA, and PMEL. UV radiation causes damage to the DNA of cells, typically
Melanoma
Enzyme found in humans
"Entrez Gene: BACE2 beta-site APP-cleaving enzyme 2". Rochin L, Hurbain I, Serneels L, Fort C, Watt B, Leblanc P, et al. (Jun 2013). "BACE2 processes PMEL to
Beta-secretase_2
Medical condition
nestin protein in 95% of cases, and S100 protein and melanocyte protein PMEL protein in some cases. DFSP-FS tumors have a DFSP-FS histopathology in 5%
Dermatofibrosarcoma protuberans, fibrosarcomatous
Dermatofibrosarcoma_protuberans,_fibrosarcomatous
"Statistics & download files". www.genenames.org. HUGO Gene Nomenclature Committee. 3 November 2025. Retrieved 3 November 2025.
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Pharmaceutical drug
consisting of the α and β chains of a T cell receptor protein targeting gp100 (PMEL, specifically the fragment presented by HLA-A*02:01) and a single-chain variable
Tebentafusp
Hydrothermal field in the mid-Atlantic Ocean
"Return to the Lost City 2018 | Earth-Ocean Interactions Program". www.pmel.noaa.gov. Retrieved 2019-04-11. "CruisePlanner Synopsis: AT42-01: Lang -
Lost_City_Hydrothermal_Field
Genetics behind the equine coat color
be affected by any number of dilution genes and patterning genes. The dilution genes include the wildtype dun gene, believed to be one of the oldest colors
Equine_coat_color_genetics
2014 nonfiction book by Elizabeth Kolbert
We Now Living in the Anthropocene?". GSA Today (18): 6. Sabine, Chris. "PMEL CO2". National Oceanic and Atmospheric Administration-Pacific Marine Environmental
The Sixth Extinction: An Unnatural History
The_Sixth_Extinction:_An_Unnatural_History
Species of mollusc
1–77. "Ocean Acidification's impact on oysters and other shellfish". www.pmel.noaa.gov. Retrieved 15 April 2018. Voss, Jn; Brown-Peterson, Nj; Delgado
Aliger_gigas
Insoluble protein aggregate with a fibrillar morphology
Functional amyloid in Homo sapiens: Intralumenal domain of melanocyte protein PMEL Peptide/protein hormones stored as amyloids within endocrine secretory granules
Amyloid
Aspect of marine biology
et al. - Impact of Anthropogenic CO2 on the CaCO3 System in the Oceans". pmel.noaa.gov. Retrieved 2016-11-05. Revelle R (1934) Physico-chemical factors
Shell_growth_in_estuaries
Geographically located ocean measurement site
sediment traps to quantify sinking particle flux. From 1997 to 1999, a NOAA PMEL surface mooring was deployed as part of the National Ocean Partnership Program
Station P (ocean measurement site)
Station_P_(ocean_measurement_site)
travel, tourism, insurance
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