Search references for PLEXIN. Phrases containing PLEXIN
See searches and references containing PLEXIN!PLEXIN
Protein
A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. It is classically known for its expression on the surface of axon
Plexin
Protein-coding gene in the species Homo sapiens
Plexin-B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene. Within neural tissues, the plexin family serves as transmembrane
Plexin-B1
Process of synapse elimination
in mice that have a Plexin-A3 defect. Specifically, axons that are connected to a transient target will retract once the Plexin-A3 receptors are activated
Synaptic_pruning
Protein-coding gene in the species Homo sapiens
PMID 15520858. Gu C, Yoshida Y, Livet J, et al. (2005). "Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins". Science. 307
SEMA3F
Protein-coding gene in the species Homo sapiens
Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. Plexin A1 has been shown to interact with AKT1. GRCh38: Ensembl release 89: ENSG00000114554
Plexin_A1
Protein found in Homo sapiens
induces growth cone collapse in the central nervous system. By binding plexin B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and
SEMA4D
Protein-coding gene in the species Homo sapiens
Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that
PLXNB2
Protein-coding gene in the species Homo sapiens
Plexin-A4 is a protein that in humans is encoded by the PLXNA4 gene. Plexin A4 binds to neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) and transduces signals
PLXNA4A
Protein-coding gene in the species Homo sapiens
Nakamura F, Wang LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99
Semaphorin-3A
Part of the brain where the optic nerves cross
(Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest
Optic_chiasm
Human chromosome
protein ORMDL sphingolipid biosynthesis regulator 3 PLXDC1: encoding protein Plexin domain-containing protein 1 PNPO: encoding enzyme Pyridoxine-5'-phosphate
Chromosome_17
Protein-coding gene in the species Homo sapiens
Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins
PLXNA2
Protein-coding gene in the species Homo sapiens
P, Fazzari P, Gilestro GF, Barberis D, Giordano S, et al. (July 2004). "Plexin-B3 is a functional receptor for semaphorin 5A". EMBO Reports. 5 (7): 710–714
SEMA5A
Protein family
receptors are called plexins, with neuropilins as their co-receptors in many cases. The main receptors for semaphorins are plexins, which have established
Semaphorin
Chinese neuroscientist
explored the role of the plexin receptor and the Rho family GTPases in central nervous system development in Drosophila. Plexins are receptors involved
Hailan_Hu
Protein-coding gene in the species Homo sapiens
Plexin-D1 is a protein that in humans is encoded by the PLXND1 gene. GRCh38: Ensembl release 89: ENSG00000004399 – Ensembl, May 2017 GRCm38: Ensembl release
PLXND1
Group of genetic disorders affecting motor neurons controlling the lower limbs
the association of L1CAM with neuropilin-1. Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor complex. Semaphorin-a3A is
Hereditary_spastic_paraplegia
Protein-coding gene in the species Homo sapiens
Plexin-B3 is a protein that in humans is encoded by the PLXNB3 gene. PLXNB3 has been shown to interact with ARHGEF11. GRCh38: Ensembl release 89: ENSG00000198753
PLXNB3
Type of cell within the eye
RGCs and the midline glia and acts along with Sema6D, mediated via the plexin-A1 receptor. VEGF-A is released from the midline directs RGCs to take a
Retinal_ganglion_cell
Protein-coding gene in the species Homo sapiens
proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based
Semaphorin_3E
Protein-coding gene in the species Homo sapiens
L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored
Neuropilin_2
neuropilin 1 and plexin A1. While some of the other class of semaphorins directly bind to plexin receptors, Sema3A does not bind to plexin directly. Instead
Collapsin response mediator protein family
Collapsin_response_mediator_protein_family
Protein-coding gene in the species Homo sapiens
signal transduction regulation of Rho protein signal transduction semaphorin-plexin signaling pathway hair cycle process Sources:Amigo / QuickGO Orthologs Species
FARP2
Renewal or physiological repair of damaged nerve tissue
and inhibits remyelination. Sema 4D(Semaphorin 4D) functions through the PlexinB1 receptor and inhibits remyelination. Sema 3A (Semaphorin 3A) is present
Neuroregeneration
Protein-coding gene in the species Homo sapiens
Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, et al. (October 1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99
Neuropilin_1
American neuroscientist
brain hemispheres. Jones took on two different research projects: studying Plexin-A1 during the postnatal development of the corpus callosum and how Tsc1
Lataisia_Jones
Protein-coding gene in the species Homo sapiens
neural crest cell migration) and appears to have similar functions for plexin and Flt-1 pathways. PTK7 was identified to be highly expressed in colon
PTK7
Protein family
also occur in the hepatocyte growth factor receptor (Uniprot: P08581), Plexin-A3 (Uniprot: P51805) and in viral proteins. CD100 (also called SEMA4D) is
Sema_domain
Protein-coding gene in the species Homo sapiens
Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene. Plexin PLXDC2 Protein domain GRCh38: Ensembl release 89:
PLXDC1
Protein receptor active in neurons
documented to regulate neurogenesis and angiogenesis by complexing with Plexin receptors/class-3 semaphorin ligands and Vascular Endothelial Growth Factor
Neuropilin
H (Mar 2003). "Identification and characterization of a novel mouse plexin, plexin-A4". Mechanisms of Development. 120 (3): 385–96. doi:10.1016/S0925-4773(02)00421-5
Tropic cues involved in growth cone guidance
Tropic_cues_involved_in_growth_cone_guidance
Protein-coding gene in the species Homo sapiens
protein 13 (NLPR13) Involved in inflammation Semaphorin-3C (SEMA3C) Binds to plexin family members and plays an important role in the regulation of developmental
C1orf21
French researcher (born 1967)
Corey S.; Poo, Mu-Ming; Tessier-Lavigne, Marc; Comoglio, Paolo M. (1999). "Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored
Alain_Chédotal
Protein-coding gene in the species Homo sapiens
L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored
SEMA7A
Protein family
Blondelle J, Singh MK, Flaherty KM, Means PC, et al. (August 2011). "Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1"
VEGF_receptor
Protein-coding gene in the species Homo sapiens
Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene. GRCh38: Ensembl release 89: ENSG00000130827 – Ensembl, May 2017 GRCm38: Ensembl release
PLXNA3
Protein-coding gene in the species Homo sapiens
Plexin domain-containing protein 2 is a protein that in humans is encoded by the PLXDC2 gene. GRCh38: Ensembl release 89: ENSG00000120594 – Ensembl, May
PLXDC2
Professor of Neurobiology
M.; Kolodkin, Alex L.; Ginty, David D. (2005-01-14). "Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins". Science. 307
Chenghua_Gu
Protein found in humans
chemoattraction of axon commissural neuron axon guidance regulation of semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse
Glial cell line-derived neurotrophic factor
Glial_cell_line-derived_neurotrophic_factor
Type of cell surface receptor
family mediates binding of VEGF in conjunction with the VEGFR1/VEGFR2 and Plexin signaling receptors, and therefore also plays a role in tumor vascular development
Co-receptor
Protein-coding gene in humans
PMID 11410591. Turner LJ, Nicholls S, Hall A (Aug 2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32): 33199–205. doi:10
AKT1
Human chromosome
PLEKHS1 encoding protein Pleckstrin homology domain containing S1 PLXDC2: plexin domain-containing protein 2 PRAP1: encoding protein Proline rich acidic
Chromosome_10
Protein-coding gene in the species Homo sapiens
(Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"
ARHGEF11
Protein-coding gene in the species Homo sapiens
347. PMID 11214970. Swiercz JM, Kuner R, Behrens J, Offermanns S (2002). "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone
SEMA4B
Type of chemical bond
Reinherz EL (January 2014). "Dynamic control of beta1 integrin adhesion by the plexinD1-sema3E axis". Proceedings of the National Academy of Sciences of the United
Catch_bond
as Huntington's chorea, fragile X syndrome and myotonic dystrophy. CD232 Plexin-C1 (PLXNC1 gene); also called Virus-encoded semaphorin protein receptor
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
protein, member A1 PCDHA4 Phospholipase A1 Phosphorylase kinase, alpha 1 Plexin A1 Polymerase (DNA directed), alpha 1 Potassium large conductance calcium-activated
List of A1 genes, proteins or receptors
List_of_A1_genes,_proteins_or_receptors
Protein-coding gene in humans
cerebral cortex radially oriented cell migration cell migration semaphorin-plexin signaling pathway positive regulation of stress fiber assembly axon guidance
RAC1
Protein-coding gene in humans
Hartwig C, Veske A, Krejcova S, Rosenberger G, Finckh U (August 2005). "Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with
RIT2
Protein-coding gene in the species Homo sapiens
(Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"
Rnd1
Protein-coding gene in the species Homo sapiens
negative regulation of axon extension involved in axon guidance semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse
SEMA4F
Endogenous tag expressed in different cells along neurogenesis and differentiated cells
LINGO-1; MAP1B/MAP5; Mical-3; NAP-22; NGFR; Nestin; Netrin-1; Neuropilin; Plexin-A1; RanBPM; Semaphorin 3A; Semaphorin 3F; Semaphorin 4D; Slit2; Slit3; Staufen;
Neuronal_lineage_marker
Mammalian protein found in Homo sapiens
regulation of autophagy branching morphogenesis of an epithelial tube semaphorin-plexin signaling pathway signal transduction positive regulation of transcription
Hepatocyte growth factor receptor
Hepatocyte_growth_factor_receptor
Protein-coding gene in humans
regulation of cell migration wound healing, spreading of cells semaphorin-plexin signaling pathway formation of radial glial scaffolds cerebral cortex development
FLNA
Group of prokaryotic enzymes
non-canonical catalysis of the Rap GTPase activating protein domain of plexin". eLife. 2 e01279. doi:10.7554/eLife.01279. PMC 3787391. PMID 24137545.
Sortase
Protein-coding gene in the species Homo sapiens
"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8
MICALL1
ideal regions. Receptor complexes for semaphorins include neuropilins and plexins. The Slit-Robo cell signaling pathway plays an important role in guiding
Pioneer_axon
Small signalling G protein
Mellor H (March 2015). "The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction". Neuroscience Letters. 590: 178–83. doi:10
Rif_(GTPase)
Protein-coding gene in the species Homo sapiens
Nirasawa H, Furuyama T, Kogo M, et al. (September 2002). "Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors".
ARHGEF12
Protein-coding gene in the species Homo sapiens
PMID 17151277. Takahashi T, Strittmatter SM (2001). "Plexina1 autoinhibition by the plexin sema domain". Neuron. 29 (2): 429–39. doi:10.1016/S0896-6273(01)00216-1
NPTX1
Cell type
regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex". Journal of Cell Biology. 183 (3): 555–66. doi:10.1083/jcb
GnRH_neuron
Protein-coding gene in the species Homo sapiens
transduction regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway regulation of catalytic activity Rho protein signal transduction
ARHGDIA
Protein-coding gene in the species Homo sapiens
proteins which possess a semaphoring (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Semaphorins
SEMA4G
Protein-coding gene in the species Homo sapiens
epidermal growth factor (EGF). PSI domain: domain found in plexins, semaphorins and integrins. Plexin are involved in the development of neural and epithelial
Multiple epidermal growth factor-like domains 8
Multiple_epidermal_growth_factor-like_domains_8
Protein-coding gene in the species Homo sapiens
"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8
MICAL3
Protein-coding gene in the species Homo sapiens
"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8
MICAL1
however, full length Slit2, through interactions with semaphorin receptor plexin-A4 regulates axonal branching. Interactions between Slit and Robo in this
Slit-Robo
Class of compounds
Sema domain (Semaphorin-like), PSI (Plexins, Semaphorins, Integrins), IPT domain (Immunoglobulin-like, Plexins, Transcription factors) and PTK (Protein
C-Met_inhibitor
Neuroscience field
axonal repellents, and activate complexes of cell-surface receptors called plexins and neuropilins. Cell adhesion molecules (CAMs): Integral membrane proteins
Axon_guidance
Protein-coding gene in the species Homo sapiens
Aurandt J, Vikis HG, Gutkind JS, et al. (2002). "The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide
RAPGEF2
Protein-coding gene in the species Homo sapiens
axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse
SEMA6C
Protein-coding gene in the species Homo sapiens
negative regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway phagocytosis cell migration positive regulation of GTPase
SH3BP1
Protein-coding gene in the species Homo sapiens
axon extension involved in axon guidance chemorepulsion of axon semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse
SEMA3B
Protein-coding gene in the species Homo sapiens
glioma cells express semaphorins and their receptors, neuropilins and plexins". Glia. 42 (4): 379–89. doi:10.1002/glia.10210. PMID 12730958. S2CID 45643250
SEMA3C
Protein-coding gene in the species Homo sapiens
angiogenesis T cell differentiation involved in immune response semaphorin-plexin signaling pathway negative chemotaxis neural crest cell migration positive
SEMA4A
Protein-coding gene in humans
6796-6807.2001. PMC 99857. PMID 11564864. Vikis HG, Li W, Guan KL (2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"
ARHGEF6
membrane-bound form by MT1-MMP (MMP-14) in tumor cells; it then interacts with plexin B1 on endothelial cells, promoting pro-angiogenic chemotaxis. Shedding of
Proteases_in_angiogenesis
Protein-coding gene in the species Homo sapiens
odontogenesis of dentin-containing tooth positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis multicellular
HAND2
Protein-coding gene in the species Homo sapiens
closure positive regulation of stress-activated MAPK cascade semaphorin-plexin signaling pathway negative chemotaxis neural crest cell migration positive
SEMA4C
Protein-coding gene in the species Homo sapiens
axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse
SEMA6A
Protein-coding gene in the species Homo sapiens
from the hippocampus, where it is involved with the receptors Neuropilin1, Plexin D1, and VEGFR2—which together make up the tripartite Semaphorin 3E receptor
MAP6
Protein-coding gene in the species Homo sapiens
Tamagnone L (Oct 2005). "p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling" (PDF). Journal of Cell Science
GRLF1
Protein-coding gene in the species Homo sapiens
mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling". Proc. Natl. Acad. Sci. U.S.A. 106 (33): 13933–8. Bibcode:2009PNAS
WNT2
Protein-coding gene in the species Homo sapiens
"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8
MICAL2
Protein-coding gene in the species Homo sapiens
1016/S1534-5807(01)00110-1. PMID 11782313. Vikis HG, Li W, Guan KL (April 2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"
RACGAP1
Endocytic pathway found in eukaryotic cells
Acetylcholine receptor 4 EGFR HGFR VEGFR PDGFR NGFR IGFR Tetrameric IL2R PlexinA1 ROBO1 Cholera toxins Shiga toxins Membrane scission is the process by
Fast endophilin-mediated endocytosis
Fast_endophilin-mediated_endocytosis
Protein-coding gene in the species Homo sapiens
of spinal motor neuron subtypes through transmembrane Semaphorin6A and PlexinA4 signaling". Neuron. 61 (3): 359–72. doi:10.1016/j.neuron.2008.12.022.
FARP1
PLEXIN
PLEXIN
PLEXIN
PLEXIN
Boy/Male
Tamil
Boy/Male
Gujarati, Hindu, Indian, Kannada
Gold
Boy/Male
Hindu, Indian
Who Give You Love
Boy/Male
Scottish American German
Welshman; stranger. Famous Bearer: Scottish hero Sir William Wallace (executed in...
Boy/Male
Indian, Sanskrit
Little Lamp; Shining; Bright
Girl/Female
Hindu
Someone who is concerned about the welfare (Hita) of others, Indian
Boy/Male
Greek
God of flocks.
Boy/Male
Muslim
Lion, Famous
Girl/Female
Australian, Czechoslovakian, Finnish, German, Latin, Polish, Swedish
Star; Fame; Glory; Strength; Firmness; Peaceful; Glorious
Girl/Female
Russian Latin
Dark.
PLEXIN
PLEXIN
PLEXIN
PLEXIN
PLEXIN