Search references for PHOSPHOPEPTIDE. Phrases containing PHOSPHOPEPTIDE
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Phosphopeptides are modified self antigens which may induce an immune response. Protein phosphorylation is a very important and frequent post-translational
Phosphopeptide
Family of proteins found in milk
"Increased remineralization of tooth enamel by milk containing added casein phosphopeptide-amorphous calcium phosphate". The Journal of Dairy Research. 73 (1):
Casein
Chemical substance
incorporated into the ACP structure. A commercial preparation of ACP is casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), derived from cow milk. It is
Amorphous_calcium_phosphate
Chemical process of introducing a phosphate
"Gas-phase intermolecular phosphate transfer within a phosphohistidine phosphopeptide dimer". International Journal of Mass Spectrometry. 367: 28–34. Bibcode:2014IJMSp
Phosphorylation
Addition of fluoride to a water supply to reduce tooth decay
experimental approaches include fluoridated sugar, polyphenols, and casein phosphopeptide–amorphous calcium phosphate nanocomplexes. A 2007 Australian review
Water_fluoridation
American biochemist
published a novel strategy to determine the sequence specificity of phosphopeptide binding domains (initially SH2 domains). Subsequently, the oriented
Lewis_C._Cantley
Nutrient-rich liquid produced by mammals
Kruif and Holt, proposes that nanoclusters of calcium phosphate and the phosphopeptide fraction of beta-casein are the centerpiece to micellar structure. Specifically
Milk
Substance to clean and maintain teeth
promotes remineralization, but is limited by bioavailable calcium. Casein phosphopeptide stabilised amorphous calcium phosphate (CPP-ACP) is a toothpaste ingredient
Toothpaste
Soft substance meant to be chewed without swallowing
polyols and carbamide. A study investigating the in situ effect of casein phosphopeptide–amorphous calcium phosphate (CPP–ACP) found that its incorporation into
Chewing_gum
Gene known for its role in breast cancer
PMID 11477095. Rodriguez M, Yu X, Chen J, Songyang Z (December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal
BRCA1
Protein domain
Shoelson SE, Fesik SW (April 1996). "Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain". Nat. Struct. Biol. 3 (4): 388–93
Phosphotyrosine-binding domain
Phosphotyrosine-binding_domain
Protein-coding gene in the species Homo sapiens
PMID 11861901. Rodriguez M, Yu X, Chen J, Songyang Z (December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal
HDAC10
Class of enzymes
Pawson T, Haser WG, et al. (March 1993). "SH2 domains recognize specific phosphopeptide sequences". Cell. 72 (5): 767–78. doi:10.1016/0092-8674(93)90404-E.
Phosphoinositide_3-kinase
Paired cells that control the stomatal aperture
activation of plasma membrane H+-ATPase activity. This was done by adding phosphopeptides such as P-950, which inhibits the binding of 14-3-3 protein, to phosphorylated
Guard_cell
Ionization technique
proteomics; mass analysis of DNA, RNA, PNA, lipids, oligosaccharides, phosphopeptides, bacteria, small molecules and synthetic polymers, similar applications
Matrix-assisted laser desorption/ionization
Matrix-assisted_laser_desorption/ionization
Protein domain
Honig B (2003). "Sequence, structure, and energetic determinants of phosphopeptide selectivity of SH2 domains". Journal of Molecular Biology. 334 (4):
SH2_domain
Type of mass spectrometer
versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning". J Mass Spectrom. 36 (7): 782–90. Bibcode:2001JMSp
Quadrupole_mass_analyzer
Chemical labels used to quantify biomolecules via mass spectrometry
detection sensitivity of certain highly hydrophilic analytes, such as phosphopeptides, in RPLC-MS analyses. There are currently six varieties of TMT available:
Tandem_mass_tag
Protein-coding gene in the species Homo sapiens
PMC 133867. PMID 12024042. Rodriguez M, Yu X, Chen J, Songyang Z (2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
Nuclear receptor coactivator 2
Nuclear_receptor_coactivator_2
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
List_of_MeSH_codes_(D12.644)
Interdisciplinary science
S (November 2012). "Fully automated isotopic dimethyl labeling and phosphopeptide enrichment using a microfluidic HPLC phosphochip". Analytical and Bioanalytical
Microfluidics
Chemical entity which can be bound by an antibody
Lewis ST, et al. (2006). "Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy". Proceedings of the National Academy
Epitope
Protein domain
molecular biology, the forkhead-associated domain (FHA domain) is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity
Forkhead-associated_domain
also exist, PepCyber and ScanSite focus on smaller subsets of motifs, phosphopeptide binding and important signaling domains respectively. PDZBase focuses
Short_linear_motif
Suspension of gold nanoparticles in a liquid
1021/la9502711. Lin HY, Chen CT, Chen YC (October 2006). "Detection of phosphopeptides by localized surface plasma resonance of titania-coated gold nanoparticles
Colloidal_gold
Mammalian protein found in Homo sapiens
N, Macura S, Chen J, et al. (July 2004). "Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains". Structure. 12 (7): 1137–1146
BRIP1
Mammalian protein found in humans
STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX 1f1w: SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN 1f2f: SRC SH2 THREF1TRP
Proto-oncogene tyrosine-protein kinase Src
Proto-oncogene_tyrosine-protein_kinase_Src
Process of introducing a phosphate group on to a protein
structure, but much more flexible for phosphates that interact with phosphopeptide-binding domains to recruit regulatory proteins. Protein phosphorylation
Protein_phosphorylation
Egg yolk phosphoprotein
Samaraweera, Himali (Sep 2011). "Egg Yolk Phosvitin and Functional Phosphopeptides—Review". Journal of Food Science. 76 (7): R143–R150. doi:10.1111/j
Phosvitin
Protein found in humans
structure of the human sigma isoform of 14-3-3 in complex with a mode-1 phosphopeptide 1yz5: The crystal structure of 14-3-3-sigma at 2.8 angstrom resolution
Stratifin
DNA replication in eukaryotic organisms
had two pairs of BRCA1 C Terminus (BRCT) domains which are known as a phosphopeptide-binding domains. The N-terminal pair of the BRCT domains binds to phosphorylated
Eukaryotic_DNA_replication
Class of protein inhibiting drugs
consisting of ovalicin (a MetAP-2 small molecule inhibitor) and IκBα phosphopeptide (a recruiter of the SCFβ-TRCP E3 ligase complex) separated by a linker
Targeted_protein_degradation
Protein-coding gene in humans
to tyrosine-phosphorylated proteins but they are different in their phosphopeptide-binding specificities. P66SHC is characterized by having an additional
SHC1
Natural repair process for non-cavitated tooth lesions
Thikrayat Bani; O'Connell, Anne C.; Duane, Brett (24 June 2016). "Casein phosphopeptide-amorphous calcium phosphate products in caries prevention". Evidence-Based
Remineralisation_of_teeth
phosphorylate Plk1 in vitro. The polo-box domain (PBD) of Plk1 is a phosphopeptide-binding motif. This means that in the absence of a phosphorylated ligand
Polo-like_kinase
Protein-coding gene in the species Homo sapiens
PMID 14519663. S2CID 24870579. Rodriguez M, Yu X, Chen J, Songyang Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
MDC1
Chemical compound
"Iodoacetamide-alkylated methionine can mimic neutral loss of phosphoric acid from phosphopeptides as exemplified by nano-electrospray ionization quadrupole time-of-flight
Iodoacetamide
Post-translational carbohydrate modification of proteins
have been shown to form functional complexes with OGT. A synthetic phosphopeptide was able to be dephosphorylated and O-GlcNAcylated by an OGT immunoprecipitate
O-GlcNAc
Mammalian protein found in humans
Roberts-Thomson M, et al. (August 2010). "Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular
PLK1
Protein found in humans
e PDB gallery 1irs: IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE 1qqg: CRYSTAL STRUCTURE OF THE PH-PTB
Insulin_receptor_substrate_1
Protein found in humans
PMID 12490152. Rodriguez M, Yu X, Chen J, Songyang Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
Centromere_protein_C
Laboratory technique to separate ions and polar molecules
Otto; Mechtler, Karl (5 May 2015). "Anion-Exchange Chromatography of Phosphopeptides: Weak Anion Exchange versus Strong Anion Exchange and Anion-Exchange
Ion_chromatography
Protein-coding gene in the species Homo sapiens
6-phosphate receptor 1lf8: Complex of GGA3-VHS Domain and CI-MPR C-terminal Phosphopeptide 1p4u: CRYSTAL STRUCTURE OF GGA3 GAE DOMAIN IN COMPLEX WITH RABAPTIN-5
GGA3
Compounds that inhibit the activity of DNA topoisomerases
DNA cleavage associated with hypophosphorylation of topoisomerase II phosphopeptides". Molecular Pharmacology. 50 (2): 243–248. doi:10.1016/S0026-895X(25)09213-2
Topoisomerase_inhibitor
Type of chromatography
Isocratic Separation of Charged Solutes and Selective Isolation of Phosphopeptides". Anal. Chem. 80 (1): 62–76. Bibcode:2008AnaCh..80...62A. doi:10.1021/ac070997p
Hydrophilic interaction chromatography
Hydrophilic_interaction_chromatography
phenylalanine - Philadelphia chromosome - phospholipid - phospholipid bilayer - phosphopeptide - phosphoprotein - phosphorus - phosphorylation - phosphoserine - phosphothreonine
Index of biochemistry articles
Index_of_biochemistry_articles
Protein-coding gene in the species Homo sapiens
N-ACETYLTRANSFERASE COMPLEX 1qja: 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) 1qjb: 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1) 2c1j: MOLECULAR BASIS FOR
YWHAZ
Protein-coding gene in the species Homo sapiens
CAN-05-0823. PMID 16140944. Rodriguez M, Yu X, Chen J, Songyang Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
CTCFL
Protein-coding gene in the species Homo sapiens
PMC 151524. PMID 12509458. Rodriguez M, Yu X, Chen J, Songyang Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
HDAC8
Protein family
Panitch, Alyssa (2005). "Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics". The FASEB Journal. 19 (2): 261–263. doi:10
Hsp20
1101/gr.180101. PMC 311163. PMID 11591653. Molloy MP, Andrews PC (2002). "Phosphopeptide derivatization signatures to identify serine and threonine phosphorylated
HSPB8
Protein-coding gene in humans
1gxc: FHA DOMAIN FROM HUMAN CHK2 KINASE IN COMPLEX WITH A SYNTHETIC PHOSPHOPEPTIDE 2cn5: CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH ADP 2cn8: CRYSTAL
CHEK2
Protein-coding gene in the species Homo sapiens
immunoreceptor tyrosine-based activation motif. Reconstitution with synthetic phosphopeptides". J. Biol. Chem. 271 (18): 10775–81. doi:10.1074/jbc.271.18.10775.
PIK3R1
Mammalian gene
Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide 2cbl: N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70
CBL_(gene)
Protein-coding gene in the species Homo sapiens
analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography". Proteomics. 8 (7): 1346–61
RNF213
Protein found in humans
FHAD1 has 4 aliases, Forkhead associated phosphopeptide binding domain 1, Forkhead-associated (FHA) phosphopeptide binding domain 1, FHA Domain-Containing
FHAD1
Protein-coding gene in humans
737. PMID 12888911. Rodriguez M, Yu X, Chen J, Songyang Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
KIF1B
Family of conserved regulatory molecules
(July 2015). "14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides". Bioinformatics. 31 (14): 2276–83. doi:10.1093/bioinformatics/btv133
14-3-3_protein
British biological mass spectrometrist
"Gas-phase intermolecular phosphate transfer within a phosphohistidine phosphopeptide dimer". International Journal of Mass Spectrometry. 367: 28–34. Bibcode:2014IJMSp
Claire_E._Eyers
Protein
signaling. Motifs that were predicted are a canonical arginine-containing phosphopeptide motif, which may be involved in the transportation of the 14-3-3 proteins
TMEM267
Medical condition
to Treat Incisors Hypomineralization (MIH): A Combined Use of Casein Phosphopeptide-Amorphous Calcium Phosphate and Hydrogen Peroxide—A Case Report". Case
Molar incisor hypomineralisation
Molar_incisor_hypomineralisation
Protein-coding gene in the species Homo sapiens
PMID 10196224. Rodriguez M, Yu X, Chen J, Songyang Z (Dec 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol
RBBP8
Protein-coding gene in humans
1158/0008-5472.CAN-05-4443. PMID 16951182. Chini CC, Chen J (2006). "Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin
CLSPN
Chinese biochemist
including multi-dimensional LC-MS/MS that can aid protein profiling, phosphopeptide enrichment, and multiplex quantitation. They applied quantitative proteomics
Zeng_Rong
Protein-coding gene in the species Homo sapiens
deoxyribosephosphate group from the end of a strand break. The BRCT domain is a phosphopeptide binding domain that is common among DNA repair proteins and is likely
DNA_polymerase_lambda
Polymer with synthetic molecular receptor
low abundant phosphopeptides from a cell lysate, outperforming titanium dioxide (TiO2) enrichment- a gold standard to enrich phosphopeptides. Recent reviews
Molecularly_imprinted_polymer
Cell and developmental biologist
, bat085. 14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides Bioinformatics 2015-03-03 DOI: 10.1093/bioinformatics/btv133 GARNL1
Carol_MacKintosh
Protein-coding gene in the species Homo sapiens
Homology-2 domain of the adapter protein SH2-B 2hdx: Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
SH2B1
Reimer, U; Schneider-Mergener, J (2004). "Profiling of generic anti-phosphopeptide antibodies and kinases with peptide microarrays using radioactive and
Peptide_microarray
Sequencing of amino acid arrangement in a protein
acquisition may also be used. For instance, specific enrichment of phosphopeptides may assist in identifying phosphorylation sites in a protein. Alternative
Protein_sequencing
Protein
v t e PDB gallery 2bbu: solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor
SOCS3
Protein-coding gene in humans
"Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping". Biochemistry. 41 (17): 5613–24. doi:10.1021/bi016075c. PMID 11969422
MAP3K11
Method in mass spectrometry
phosphorylation with a minimum number of losses of phosphates and for phosphopeptide/phosphoprotein mapping, which makes ECD a superior technique. ECD has
Electron-capture_dissociation
Family of enzymes important in cell signaling
"Gas-phase intermolecular phosphate transfer within a phosphohistidine phosphopeptide dimer". Int J Mass Spectrom. 367: 28–34. Bibcode:2014IJMSp.367...28G
Histidine_kinase
Field of study in cancer research
Histone 2A. MDC1, mediator of DNA damage checkpoint 1, binds to the phosphopeptide, and phosphorylation of H2AX may spread by a positive feedback loop
Cancer_epigenetics
Protein-coding gene in the species Homo sapiens
IA, Lowery DM, Nguyen A, Yaffe MB (October 2003). "BRCT repeats as phosphopeptide-binding modules involved in protein targeting". Science. 302 (5645)
PAXIP1
Protein-coding gene in the species Homo sapiens
IA, Lowery DM, Nguyen A, Yaffe MB (October 2003). "BRCT repeats as phosphopeptide-binding modules involved in protein targeting". Science. 302 (5645):
TOPBP1
; Cantley, Lewis C. (1997-12-26). "The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity". Cell. 91 (7): 961–971. doi:10.1016/S0092-8674(00)80487-0
Katrin_Rittinger
Canadian chemist; CEO of Visions of Science Network for Learning
tool for the selective sequestration of ATP and PPi to aid in-solution phosphopeptide detection assays." Analyst. 2016 Feb 7;141(3):820-2. Duodu E, Kraskouskaya
Eugenia_Duodu_Addy
Chinese American biochemist
holoenzyme of propionyl-coenzyme A carboxylase, human symplekin-Ssu72-CTD phosphopeptide complex, histone mRNA stem-loop, human stem-loop binding protein and
Liang_Tong
Branch of proteomics
digested, peptides are separated using ion exchange chromatography; phosphopeptides are enriched using phosphospecific antibodies, immobilized metal affinity
Phosphoproteomics
Protein-coding gene in the species Homo sapiens
SH2 domain bound to a phosphopeptide 2etz: The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide 1lun: NMR Structure of
ITK_(gene)
Protein-coding gene in the species Homo sapiens
S2CID 41514608. Rodriguez M, Yu X, Chen J, Songyang Z (December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal
MAP4K4
Defect of tooth enamel when it is softer than normal
fluoride uptake and reducing enamel breakdown. Additionally, casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) based products, derived from casein
Enamel_hypocalcification
Protein-coding gene in Homo sapiens
homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site". The Journal of Biological Chemistry.
MEMO1
Protein-coding gene in humans
immunoreceptor tyrosine-based activation motif. Reconstitution with synthetic phosphopeptides". J. Biol. Chem. 271 (18): 10775–81. doi:10.1074/jbc.271.18.10775.
FCGR2A
Protein-coding gene in the species Homo sapiens
Ratnofsky S, Lechleider RJ (Mar 1993). "SH2 domains recognize specific phosphopeptide sequences". Cell. 72 (5): 767–78. doi:10.1016/0092-8674(93)90404-E.
Embryonal fyn-associated substrate
Embryonal_fyn-associated_substrate
Protein-coding gene in the species Homo sapiens
domain 1py1: Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide 1ujj: VHS domain of human GGA1 complexed with C-terminal peptide from
GGA1
Dutch chemist
introduction of the material TiO2 as a method for the targeted analysis of phosphopeptides in 2004. The methods developed by Heck have been adopted by many scientists
Albert_J._R._Heck
Protein-coding gene in the species Homo sapiens
PMID 12879007. Rodriguez M, Yu X, Chen J, Songyang Z (December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal
DNAJA3
metallic surfaces which adsorb some negatively charged molecules such as phosphopeptides. A typical pressure injection cell holds a micro-tube or a vial in
Pressure_injection_cell
Protein-coding gene in humans
Perich JW, Reynolds EC, Pinna LA (June 1991). "A synthetic beta-casein phosphopeptide and analogues as model substrates for casein kinase-1, a ubiquitous
CSNK1D
versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning". J Mass Spectrom. 36 (7): 782–90. Bibcode:2001JMSp
Hybrid_mass_spectrometer
Protein-coding gene found in humans
Robinson PJ, Roepstorff P (2004). "Improved detection of hydrophilic phosphopeptides using graphite powder microcolumns and mass spectrometry: evidence
DNM3
American chemist
uses negative precursor ion mass spectrometry to discover and count phosphopeptides. Ahn has identified numerous different proteins with this method and
Natalie_Ahn
travel, tourism, insurance
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