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Chemical compound
Phenylpyruvic acid is the organic compound with the formula C6H5CH2C(O)CO2H. It is a keto acid. The compound exists in equilibrium with its (E)- and (Z)-enol
Phenylpyruvic_acid
Amino acid metabolic disorder
substance causing the odor in the urine was phenylpyruvic acid. The children, he concluded, had excess phenylpyruvic acid in the urine, the condition which came
Phenylketonuria
Chemical compound
dehydratase to phenylpyruvic acid, which is a precursor of phenylalanine. prephenic acid CO2 + H2O CO2 + H2O phenylpyruvic acid Alternatively,
Prephenic_acid
Chemical compound
via phenylacetic acid, which is hydroxylated. Phenylpyruvic acid is another precursor to mandelic acid. Derivatives of mandelic acid are formed as a result
Mandelic_acid
interconverts phenylalanine and phenylpyruvic acid: phenylalanine + α-ketoglutaric acid phenylpyruvic acid + L-glutamic acid This enzyme is a transferase
Aromatic-amino-acid transaminase
Aromatic-amino-acid_transaminase
Chemical compound
Phenylalanine undergoes biotransformation to form an alpha-keto acid, phenylpyruvic acid, which can tautomerize to a reactive enol. The benzylic carbon
Hippuric_acid
Class of enzymes
interconverts phenylalanine and phenylpyruvic acid: phenylalanine + glyoxylic acid phenylpyruvic acid + glycine This enzyme is a transferase
Aromatic-amino-acid—glyoxylate transaminase
Aromatic-amino-acid—glyoxylate_transaminase
Chemical compound
γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a depressant drug. It is a precursor to
Γ-Hydroxybutyric_acid
Index of chemical compounds with the same molecular formula
seeds of Phytolacca americana Coumaric acids o-Coumaric acid p-Coumaric acid m-Coumaric acid Phenylpyruvic acid Diformylcresol Nadic anhydride This set
C9H8O3
Organic compounds with a –COOH group and a C=O group
extensive chemistry as acylation agents. Furthermore, alpha-keto acids such as phenylpyruvic acid are endogenous sources for carbon monoxide (as a gasotransmitter)
Keto_acid
Norwegian physician and biochemist
substance causing the odor in the urine was phenylpyruvic acid. The children, he concluded, had excess phenylpyruvic acid in the urine, the condition which came
Ivar_Asbjørn_Følling
phenylalanine + pyruvic acid phenylpyruvic acid + alanine The two substrates of this enzyme are L-phenylalanine and pyruvic acid. Its products are
Phenylalanine(histidine) transaminase
Phenylalanine(histidine)_transaminase
Chemical compound
N-methyl-2-pyrrolidone. In humans, GBL acts as a prodrug for gamma-hydroxybutyric acid (GHB) and is often used as a recreational drug. GHB acts as a central nervous
Γ-Butyrolactone
D-phenylalanine: D-phenylalanine + a quinone H2O NH3 H2O NH3 phenylpyruvic acid + a quinol This enzyme is iron-sulfur flavoprotein. Tanigawa M,
D-amino acid dehydrogenase (quinone)
D-amino_acid_dehydrogenase_(quinone)
One of four stable isomers of butanediol
HOCH2CH2CH2CH2OH. It is a colorless viscous liquid first synthesized in 1890 via acidic hydrolysis of N,N'-dinitro-1,4-butanediamine by Dutch chemist Pieter Johannes
1,4-Butanediol
Anticholinergic medication used as antidote for nerve agent poisoning
transamination forming phenylpyruvic acid which is then reduced to phenyl-lactic acid. Coenzyme A then couples phenyl-lactic acid with tropine forming littorine
Atropine
chemical reactions that interconverts L-tryptophan and phenylpyruvic acid with indole-3-pyruvic acid and L-phenylalanine. The enzyme has also been found
Tryptophan—phenylpyruvate transaminase
Tryptophan—phenylpyruvate_transaminase
Chemical compound
γ-Hydroxyvaleric acid (GHV), also known as 4-methyl-GHB, is a designer drug related to γ-hydroxybutyric acid (GHB). It is sometimes seen on the grey market
Γ-Hydroxyvaleric_acid
Chemical compound
Aceburic acid (INN), also known as 4-acetoxybutanoic acid or 4-hydroxybutyric acid acetate, is a drug described as an analgesic which was never marketed
Aceburic_acid
Organic compounds of the form >C=O
doi:10.15227/orgsyn.005.0037. Herbst, R. M.; Shemin, D. (1939). "Phenylpyruvic acid". Organic Syntheses. 19: 77. doi:10.15227/orgsyn.019.0077. Evans,
Ketone
that catalyzes the chemical reaction aspartic acid + phenylpyruvic acid oxaloacetic acid + phenylalanine The two substrates of this enzyme
Aspartate—phenylpyruvate transaminase
Aspartate—phenylpyruvate_transaminase
Chemical compound
sugars using acid catalysts. The resulting glucose can then be dehydrated via hydroxymethylfurfural to yield formic acid and levulinic acid, which cyclises
Γ-Valerolactone
Medication to treat symptoms of narcolepsy
withdrawal syndrome. Sodium oxybate is the sodium salt of γ-hydroxybutyric acid (GHB). The clinical trials for narcolepsy were conducted just as abuse of
Sodium_oxybate
substituted oxophenylpropanoic acids (phenylpyruvic acids). Terphenylquinones are typical constituents of the Boletales. Thelephoric acid Burkhard Fugmann, ed.
Terphenylquinones
catalyzes the chemical reaction phenylalanine + NAD+ H2O H+ H2O H+ phenylpyruvic acid + NADP + NH3 The three substrates of this enzyme are L-phenylalanine
Phenylalanine_dehydrogenase
Medication for nausea, psychosis, and anxiety
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Prochlorperazine
1.51) catalyzes the chemical reaction: prephenic acid CO2 + H2O CO2 + H2O phenylpyruvic acid This enzyme belongs to the family of lyases, specifically
Prephenate_dehydratase
Atypical antipsychotic
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Sulpiride
Class of drugs
anxiolytics. Butyric acid (butanoic acid) – histone deacetylase inhibitor and full agonist of free fatty acid receptor 2, free fatty acid receptor 3, and niacin
GABA_analogue
Atypical antipsychotic and antiemetic medication
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Amisulpride
Combination drug
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Xywav
Investigational drug
Parkinson's disease. The drug is taken orally once per night. It is an amino acid (L-valine) ester prodrug of GHB, which itself acts as a GABAB and GHB receptor
Valiloxybate
that catalyzes the chemical reaction glutamine + phenylpyruvic acid 2-oxoglutaramic acid + phenylalanine The two substrates of this enzyme
Glutamine—phenylpyruvate transaminase
Glutamine—phenylpyruvate_transaminase
4-sided ring molecule (C2H2O4)
peroxidation Peroxidation of the reactive enol of alpha keto acids, such as the tautomer of phenylpyruvic acid at the benzylic carbon, can form a fluorescing 1,2-dioxetane
1,2-Dioxetane
Chemical compound
4-Hydroxy-4-methylpentanoic acid (UMB68) is a tertiary alcohol, similar in structure to the drug GHB. The molecule has been synthesized and tested on animals
4-Hydroxy-4-methylpentanoic acid
4-Hydroxy-4-methylpentanoic_acid
Chemical compound
3-Chloropropanoic acid (also known as 3-chloropropionic acid or UMB66) is the organic compound with the formula ClCH2CH2CO2H. A white or colorless solid
3-Chloropropanoic_acid
Chemical compound
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Gallocatechol
Chemical compound
(R) HOCPCA (3-hydroxycyclopent-1-enecarboxylic acid) is a compound with an affinity for the GHB receptor 39 times greater than that of GHB itself. T-HCA
HOCPCA
Chemical compound
trans-4-Hydroxycrotonic acid (T-HCA), also known as γ-hydroxycrotonic acid (GHC), is an agent used in scientific research to study the GHB receptor. It
T-HCA
Pharmaceutical compound
4-Butanediol (1,4-BD) 1,6-Dioxecane-2,7-dione γ-Butyrolactone (GBL) Aceburic acid Ethyl acetoxy butanoate Glyceryl-tris-3-hydroxybutyrate (3GHB) Tributyrin
1,2,3-Tris(4-hydroxybutyroyloxy)propane
1,2,3-Tris(4-hydroxybutyroyloxy)propane
Chemical compound
γ-crotonolactone (GCL), as it is formally the lactone derived from γ-hydroxyisocrotonic acid. The chemical is colloquially called "butenolide", and is the parent structure
2-Furanone
GHB receptor coding gene in the species Homo sapiens
(GPCR) that binds the neurotransmitter and psychoactive drug γ-hydroxybutyric acid (GHB). As solute carrier family 52 member 2 (SLC52A2), it is also a transporter
GHB_receptor
Chemical compound
intermediate in the biosynthesis of the neurotransmitter γ-hydroxybutyric acid (GHB) from 1,4-butanediol (1,4-BD). Like 1,4-BD, it also behaves as a prodrug
Γ-Hydroxybutyraldehyde
the enzyme that can deaminate the amino acid phenylalanine into the products ammonia and phenylpyruvic acid. The test is performed by adding phenylalanine
Diagnostic_microbiology
Dopamine antagonist medication
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Levosulpiride
Pharmaceutical compound
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
JZP-386
Chemical compound
other aromatic alpha-keto acid-derived compounds, such those from L-phenylalanine like ralfuranone B via phenylpyruvic acid, and from L-tryptophane like
Atromentin
Chemical compound
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Monastrol
Chemical compound
sodium ethoxide. 1,4-Butanediol (1,4-BD) 1,6-Dioxecane-2,7-dione Aceburic acid gamma-Hydroxybutyraldehyde Valiloxybate Umano RP, Hagi Y, Nakahara K, Shoji
Ethyl_acetoxy_butanoate
American microbiologist (1916–1995)
PKU at the time was mixing urine with ferric chloride. The excess phenylpyruvic acid in the urine of an individual with PKU would produce a bright green
Robert Guthrie (microbiologist)
Robert_Guthrie_(microbiologist)
Chemical compound
"α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)". Proceedings of the National Academy of Sciences of the United States
Gabazine
Group of chemical compounds
phenylated substances like phenylacetic and phenylpyruvic acids. Other compounds like atromentin and thelephoric acid can also be isolated from fungi in the
Naturally_occurring_phenols
Antipsychotic medication
Benzoic acid BHB Butyric acid CHCA DBDS DIDS Hexanoic acid Lactic acid Luteolin Niflumic acid NPPB Phenylpyruvic acid Phloretin Probenecid Pyruvic acid Quercetin
Sultopride
BM (1957). "Enzymic catalysis of the keto-enol tautomerization of phenylpyruvic acids". J. Biol. Chem. 225 (2): 675–88. doi:10.1016/S0021-9258(18)64866-5
Phenylpyruvate_tautomerase
Brazilian biochemist (1923-1994)
horseradish peroxidase. An example mechanism resides in keto acids such as phenylpyruvic acid, which under certain circumstances tautomerizes to form a reactive
Giuseppe_Cilento
Chemical compound
of pharmacology of NCS-382, a putative antagonist of gamma-hydroxybutyric acid (GHB) receptor". CNS Drug Reviews. 10 (3): 243–260. doi:10.1111/j.1527-3458
NCS-382
607.812 – pyruvates MeSH D02.241.607.812.601 – phenylpyruvic acids MeSH D02.241.607.812.800 – pyruvic acid MeSH D02.355.291.205 – ciguatoxins MeSH D02.355
List_of_MeSH_codes_(D02)
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PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
PHENYLPYRUVIC ACID
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