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Chemical compound
Phenylacetic acid (conjugate base phenylacetate) is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It
Phenylacetic_acid
Trace amine
(MAO-B) and then aldehyde dehydrogenase (ALDH), which converts it to phenylacetic acid. This means that for significant concentrations to reach the brain
Phenethylamine
Nonsteroidal anti-inflammatory drug
"diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid. It was patented in Germany in 1978 by Ciba-Geigy (now Novartis).
Diclofenac
Chemical compound
trans-cinnamate via phenylacetic acid, which is hydroxylated. Phenylpyruvic acid is another precursor to mandelic acid. Derivatives of mandelic acid are formed
Mandelic_acid
Technique for solving problems in the planning of organic syntheses
from a single product. Shown below is a retrosynthetic analysis of phenylacetic acid: In planning the synthesis, two synthons are identified: a nucleophilic
Retrosynthetic_analysis
Chemical compound
2-Nitrophenylacetic acid is an organic compound used in organic synthesis that has also been used as an herbicide. It is a derivative of phenylacetic acid, containing
(2-Nitrophenyl)acetic_acid
Chemical compound
4-Bromophenylacetic acid, also known as p-bromophenylacetic acid, is an organic compound. It is a derivative of phenylacetic acid containing a bromine
4-Bromophenylacetic_acid
Chemical compound
the gas-phase ketonic decarboxylation of phenylacetic acid using acetic acid over a ceria-alumina solid acid catalyst. A related laboratory-scale reaction
Phenylacetone
Chemical compound
Cinnamic acid is an organic compound with the formula C6H5−CH=CH−COOH. It is a white crystalline compound that is slightly soluble in water, and freely
Cinnamic_acid
Plant hormone
include indole-3-acetic acid, 4-chloroindole-3-acetic acid, phenylacetic acid, indole-3-butyric acid, and indole-3-propionic acid. However, most of the
Auxin
Oxyacid of phosphorus
and α-methylstyrene, acid-catalyzed alkyl migrations lead instead to the main products phenylacetic acid and 2-phenylpropionic acid, respectively. The oxidation
Peroxymonophosphoric_acid
Antihistamine medication
for this interaction, including the piperidine nitrogen, the carboxylic acid (-COOH) group, and both hydroxyl (-OH) groups. The older antihistaminic agent
Fexofenadine
Chemical compound
Phenylacetaldehyde is readily oxidized to phenylacetic acid. Therefore will eventually be hydrolyzed and oxidized to yield phenylacetic acid that will be excreted primarily
Phenylacetaldehyde
Organic compound (C6H5COOH)
Benzoic acid (/bɛnˈzoʊ.ɪk/) is a white or colorless crystalline organic compound with the formula C6H5COOH, whose structure consists of a benzene ring
Benzoic_acid
Chemical compound
nitriles. It can be hydrolyzed to give phenylacetic acid or it can be used in the Pinner reaction to yield phenylacetic acid esters. Hydrogenation gives β-phenethylamine
Benzyl_cyanide
Southeast Asian fruit
organic compounds, including beta-damascenone, vanillin, phenylacetic acid, and cinnamic acid. Well over 200 cultivars have been developed from selected
Rambutan
Chemical compound
ketone is prepared by ketonic decarboxylation of phenylacetic acid. One method is where phenylacetic acid is reacted with acetic anhydride and anhydrous
Dibenzyl_ketone
Chemical compound
4-methylmethamphetamine, Wy-28342, PheTQS, & Imrecoxib (via the mandelic acid FGI to the phenylacetic acid). Coleman, G. H.; Craig, David (1932). "p-Tolualdehyde". Org
4-Methylbenzaldehyde
Chemical compound
phenylacetate is an organic compound that is the methyl ester of phenylacetic acid, with the structural formula C6H5CH2CO2CH3. It is a colorless liquid
Methyl_phenylacetate
Substances used to manufacture illicit drugs
manufacture of narcotic drugs and psychoactive substances. For example, phenylacetic acid is used legally in the production of penicillin, flavourings, perfume
Drug_precursors
Chemical compound
DCC, formic acid, and a strong base such as sodium methoxide. In the presence of DMAP, DCC self-condenses two molecules of phenylacetic acid and its substituted
N,N'-Dicyclohexylcarbodiimide
Class of enzymes
carboxylate + 6-aminopenicillanic acid For example, in Escherichia coli, benzylpenicillin is converted to 6-APA and phenylacetic acid: benzylpenicillin H2O
Penicillin_amidase
Chemical reaction
pyridine) is the conversion of acetophenone to 2-phenylacetamide and phenylacetic acid The related Willgerodt–Kindler reaction takes place with elemental
Willgerodt_rearrangement
Chemical compound
Phenylpropanoic acid or hydrocinnamic acid is a carboxylic acid with the formula C9H10O2 belonging to the class of phenylpropanoids. It is a white, crystalline
Phenylpropanoic_acid
ω-phenylalkanoic acids have long been known to occur in natural products. Phenylacetic, 3-phenylpropanoic and 3-phenylpropenoic (cinnamic) acids are found in
Phenyl_alkanoic_acids
Transnational drug-trafficking organization
(phenyl-2-propanone) is usually obtained from phenylacetic acid and acetic anhydride, with phenylacetic acid possibly arising from benzaldehyde, benzylcyanide
Sinaloa_Cartel
Chemical compound
Mosher's acid, or α-methoxy-α-trifluoromethylphenylacetic acid (MTPA) is a carboxylic acid which was first used by Harry Stone Mosher as a chiral derivatizing
Mosher's_acid
methyl ethyl ketone or MEK) Toluene Hydrochloric acid (including anhydrous hydrogen chloride) Sulfuric acid Methyl isobutyl ketone (MIBK) Sodium permanganate
DEA_list_of_chemicals
Index of chemical compounds with the same molecular formula
benzoate Phenyl acetate Phenylacetic acid Piceol and other hydroxy acetophenones Toluic acids p-Toluic acid o-Toluic acid m-Toluic acid This set index page
C8H8O2
Chemical compound
prepared by the Ivanov reaction between phenylacetic acid and formaldehyde. In this method, the dianion of the acid is formed using a Grignard reagent, isopropyl
Tropic_acid
Chemical compound
Benzilic acid is an organic compound with formula C 14H 12O 3 or (C 6H 5)2(HO)C(COOH). It is a white crystalline aromatic acid, soluble in many primary
Benzilic_acid
Chemical compound
Homogentisic acid (2,5-dihydroxyphenylacetic acid) is a phenolic acid usually found in Arbutus unedo (strawberry-tree) honey. It is also present in the
Homogentisic_acid
methylamine, P2P was usually obtained from phenylacetic acid and acetic anhydride, and phenylacetic acid might arise from benzaldehyde, benzylcyanide
History and culture of substituted amphetamines
History_and_culture_of_substituted_amphetamines
Index of chemical compounds with the same name
refer to: Phenyl acetate, the ester of phenol and acetic acid The conjugate base of phenylacetic acid This set index article lists chemical compounds articles
Phenylacetate
Hypothetical unit in retrosynthetic analysis
potentially very unstable charged synthons. In planning the synthesis of phenylacetic acid, two synthons are identified: a nucleophilic "COOH−" group, and an
Synthon
Brazil's federal drug control statute
(N-Phenyl-4-piperidinamine) 23056-29-3 Anthranilic acid Phenylacetic acid Lysergic acid N-Acetylanthranilic acid Alpha-phenylacetoacetonitrile (APAAN) (CAS:
Brazilian Controlled Drugs and Substances Act
Brazilian_Controlled_Drugs_and_Substances_Act
Chemical reaction
possible with some reagents. Use of the dianion of phenylacetic acid with formaldehyde gives tropic acid, an intermediate used in the synthesis of atropine
Ivanov_reaction
Reagent for converting a chemical compound to a chiral derivative
(α-methoxy-α-(trifluoromethyl)phenylacetic acid), also known as Mosher's acid. The corresponding acid chloride is also known as Mosher's acid chloride, and the resultant
Chiral_derivatizing_agent
Law of Singapore
1'-Oxybisethane Hydrochloric acid Methyl ethyl ketone also known as 2-Butanone Phenylacetic acid also known as Benzeneacetic acid or a-Toluic acid Piperidine also
Misuse of Drugs Act (Singapore)
Misuse_of_Drugs_Act_(Singapore)
the chemical reaction phenylacetaldehyde + NAD+ H2O H+ H2O H+ phenylacetic acid + NADH The three substrates of this enzyme are phenylacetaldehyde
Phenylacetaldehyde dehydrogenase
Phenylacetaldehyde_dehydrogenase
Species of bacterium
that the N-terminal Gly is substituted with phenylacetic acid. This is the first instance of phenylacetic acid found in the murein of bacterial cells. The
Thermus_thermophilus
Chemical compound
Carbon acids which can be deprotonated by sodium amide in liquid ammonia include: Terminal alkynes Methyl ketones Cyclohexanone Phenylacetic acid and its
Sodium_amide
Chemical compound
3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One
3,4-Dihydroxyphenylacetic acid
3,4-Dihydroxyphenylacetic_acid
Aromatic organochlorine compound
from benzyl chloride. The resulting benzyl cyanide is a precursor to phenylacetic acid, a precursor to pharmaceuticals and commercial fragrances. Phenols
Benzyl_chloride
Chemical compound
and 7-nitrobenzimidazoles. Varying the choice of the substituted phenylacetic acid imino ether affords compounds with a diversity of substituents on
Etonitazene
Antihistamine medication
T, Tsukada W (July 1976). "6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity". Journal of Medicinal Chemistry.
Olopatadine
Wound care by maggot therapy
have broad-spectrum antimicrobial activity include allantoin, urea, phenylacetic acid, phenylacetaldehyde, calcium carbonate, proteolytic enzymes, and many
Maggot_therapy
Drugs used to achieve relief from pain
PMID 9646006. S2CID 46662001. "PRODUCT INFORMATION PONSTAN CAPSULES (mefenamic acid)" (PDF). TGA eBusiness Services. Pfizer Australia Pty Ltd. 12 October 2012
Analgesic
Species of the family Mustelidae
3-methylbutanoic acid, 2-methylbutanoic acid, phenylacetic acid, alpha-tocopherol, cholesterol, and a compound tentatively identified as 2-methyldecanoic acid. The
Wolverine
Cox-2 inhibitor anti-inflammatory drug
substituted by fluorine, the phenylacetic acid has another methyl group in meta position), making it a member of the arylalkanoic acid class of NSAIDs; it binds
Lumiracoxib
Chemical compound
were 1.9 hours (range 0.8–7.4 hours) for phenylbutyric acid, 1.0–1.8 hours for phenylacetic acid (PAA), and 1.9–16.9 hours for phenylacetylglutamine (PAGN)
Glycerol_phenylbutyrate
Chemical compound
2-[4-[(3S)-3-[[(1R)-1-Naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]acetic acid CAS Number 870964-67-3 PubChem CID 71242808 DrugBank DB12388 ChemSpider 44208828
Evocalcet
Chemical compound
similar fragmentation by oxidative intramolecular ring closure from phenylacetic acid also yields only modest returns (< 20%) due to the oxidation sensitivity
2-Coumaranone
Non-steroidal anti-inflammatory drug
Janssen PA, Van Daele GH, Boey JM, "Antiphlogistic aroyl-substituted phenylacetic acid derivatives", issued 1974 Nies AS (1988). "Renal Effects of Nonsteroidal
Suprofen
Chemical compound
the ester resulting from the esterification of allyl alcohol and phenylacetic acid. It has not been reported to be found in nature. Allyl phenylacetate
Allyl_phenylacetate
Genus of fungi
fungus garden with this phenylacetic acid. Bioassays showed that Escovopsis from leafcutter ants is not as affected by the acid than that from more basic
Escovopsis
Chemical compound
is also possible to produce phenethyl alcohol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF. Phenethyl alcohol is found
Phenethyl_alcohol
American cigarette brand
cigarettes contain 26 additional ingredients, which include: molasses, phenylacetic acid, and the oil of patchouli. L&M was the fourth-largest cigarette brand
L&M
Medication of the barbiturate type
these methods consists of a Pinner reaction of benzyl cyanide, giving phenylacetic acid ethyl ester. Subsequently, this ester undergoes cross Claisen condensation
Phenobarbital
American crime drama TV series (2008–2013)
also known as phenylacetone or P2P, being produced from phenylacetic acid and acetic acid with a tube furnace and thorium dioxide catalyst, and later
Breaking_Bad
Chemical compound
via Perkin reaction in dimethyl sulfoxide from methoxy-substituted phenylacetic acid and methoxy- or ethoxy-substituted salicylaldehyde using the dehydrating
3-Phenylcoumarin
relevant synthetic precursors, including P2P, phenylacetic acid, MDP2P, safrole, isosafrole, piperonal, lysergic acid, ergotamine, and ergometrine, among others
Legal status of psychedelic drugs in Canada
Legal_status_of_psychedelic_drugs_in_Canada
Enclosed area surrounding a house
the home, namely that it was being used to store large amounts of phenylacetic acid (used in the illegal manufacture of drugs) and that it had a very
Curtilage
Species of bacterium
2001). "Isolation and In Vivo and In Vitro Antifungal Activity of Phenylacetic Acid and Sodium Phenylacetate from Streptomyces humidus". Applied and Environmental
Streptomyces_humidus
Canadian federal drug regulation act
glycidate) 3-oxo-2-phenylbutanamide (α- phenylacetoacetamide-APAA) Phenylacetic acid and its salts Piperidine and its salts Piperonal (1,3-benzodioxole-5-carboxaldehyde)
Controlled Drugs and Substances Act
Controlled_Drugs_and_Substances_Act
Type of drugs
mitochondria which deaminates free primary and secondary amines) to form phenylacetic acid due to MAO-B selectivity on non-polar aromatic amines. Then, the metabolites
Synthetic_drug
4-Phenyl-3-buten-2-one Phenylacetaldehyde Phenylacetic acid L-Phenylalanine 3-Phenylpropionaldehyde 3-Phenylpropionic acid 3-Phenylpropyl acetate 3-Phenylpropyl
List of additives in cigarettes
List_of_additives_in_cigarettes
Chemical compound
This is an organic ammonium salt of mandelic acid. The compound can be prepared by reacting mandelic acid and ammonia or excess of strong ammonia water
Ammonium_mandelate
Aspect of medical history
penicillin of X-1612, but in the form of the less desirable penicillin K. Phenylacetic acid was added to switch it to producing the highly potent penicillin G
History_of_penicillin
Chemical compound
An alternative procedure is described: Phthalic anhydride (1) and phenylacetic acid (2) in the presence of sodium acetate also gives benzalphthalide [575-61-1]
Dibenzosuberone
Class of enzymes
Olivera ER, Luengo JM, García JL, Díaz E (October 1998). "Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway"
Oxepin-CoA_hydrolase
Irreversible non-selective MAO inhibitor and antidepressant drug
route of metabolism, and the major metabolites are phenylacetic acid and parahydroxyphenylacetic acid, recovered as about 73% of the excreted dose of phenelzine
Phenelzine
Drug control treaty
N-Acetylanthranilic acid ephedrine ergometrine ergotamine isosafrole lysergic acid 3,4-methylenedioxyphenyl-2-propanone norephedrine phenylacetic acid 1-phenyl-2-propanone
United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances
United_Nations_Convention_Against_Illicit_Traffic_in_Narcotic_Drugs_and_Psychotropic_Substances
Operational technique in biotechnological processes
, glucose) and penicillin precursors (e.g., phenylacetic acid). Subsequently, in the field of amino acid fermentation—an industry pioneered by Japan starting
Fed-batch_culture
Chemical compound
amide of vanillylamine and ricinoleic acid, with the hydroxyl group on ricinoleic acid esterified with phenylacetic acid. It is used to study the function
Phenylacetylrinvanil
being the salts of cathine. red phosphorus acetic anhydride phenylacetic acid anthranilic acid piperidine potassium permanganate The salts of the substances
European law on drug precursors
European_law_on_drug_precursors
Topics referred to by the same term
School Peroxyacetic acid, a chemical Pharmacologic Ascorbic Acid, a medical treatment Phenylacetic acid, a chemical Phosphoamino acid analysis, a biochemistry
PAA
Neural, cognitive, and behavioral effects of physical exercise
urinary β-phenylacetic acid, the primary metabolite of phenethylamine. Two reviews noted a study where the average 24 hour urinary β-phenylacetic acid concentration
Neurobiological effects of physical exercise
Neurobiological_effects_of_physical_exercise
Photochemical reaction
9, doi:10.15227/orgsyn.002.0009. Roger Adams, A. F. Thal: Phenylacetic Acid [α-Toluic acid]. In: Organic Syntheses. 2, 1922, p. 63, doi:10.15227/orgsyn
Photochlorination
Atypical antipsychotic medication
a phenylacetic acid derivative after acid hydrolysis of the amide intermediate. Cyclization of this compound in the presence of polyphosphoric acid forms
Zotepine
Enzyme
isomerase to obtain phenylacetaldehyde, which can be transformed into phenylacetic acid by phenylacetaldehyde dehydrogenase. The enzyme belongs to the group
Styrene_monooxygenase
Chemical reaction
diazoacetophenone with silver (I) oxide and water resulted in formation of phenylacetic acid. Similarly, treatment with silver (I) oxide and ammonia formed phenylacetamide
Wolff_rearrangement
Chemical compound
salts with citric acid; basic salts, such as tartaric acid, adipic acid, malic acid, gluconic acid, phenylacetic acid, valeric acid. Other precipitates
Thorium(IV)_nitrate
from Pseudomonas putida. A specific enzyme for the catabolism of phenylacetic acid". J. Biol. Chem. 265 (12): 7084–90. doi:10.1016/S0021-9258(19)39262-2
Phenylacetate—CoA_ligase
Ability of bacteria to break down plastic polymers
polystyrene molecule is transformed into phenylacetic acid during the upper pathway of styrene metabolism. Phenylacetic acid is first converted into phenylacetyl-coA
Plastic degradation by marine bacteria
Plastic_degradation_by_marine_bacteria
Pharmaceutical compound
α-dideutero mescaline would be compromised by this conversion to the phenylacetic acid, but still could be valuable as a measure of the chiral position sensitivity
Alpha-D
Pharmaceutical compound
experimental drug which acts as a mixed agonist-antagonist for certain free fatty acid receptors, being an agonist at FFAR1 (GPR40) but an antagonist at GPR84.
Fezagepras
Acetone Anthranilic acid Diethyl ether Hydrochloric acid Methyl ethyl ketone Phenylacetic acid Piperidine Potassium permanganate Sulfuric acid Toluene Drug policy
Decree-Law_15/93
Trace amine
breaks down into phenylacetaldehyde which is further broken down into phenylacetic acid by monoamine oxidase. When this is inhibited by monoamine oxidase
N-Methylphenethylamine
Amino acid metabolites
addition, decreases in the urine and plasma levels of the PE metabolite phenylacetic acid and the precursors phenylalanine and tyrosine have been reported along
Trace_amine
Chemical compound
activity was due to the replacement of the D-α-aminoadipic acid side chain with phenylacetic acid. Cephalosporin C is the product of a natural biosynthesis
Cephalosporin_C
Chemical compound
Jin-Quan Yu (2015). "Ligand-Accelerated ortho-C-H Olefination of Phenylacetic Acids". Org. Synth. 92: 58–75. doi:10.15227/orgsyn.092.0058. PMC 4936495
Palladium(II)_acetate
Chemical compound
Buphenyl among others, is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. The compound is used to treat urea cycle disorders
Sodium_phenylbutyrate
Species of bacterium
D-aspartic acid, glycyl-L-proline, L-alanine, L-arginine, L-serine, pectine, D-saccharic acid, p-hydroxy-phenylacetic acid, methyl pyruvate, citric acid, bromo-succinic
Rhizobium_lentis
Chemical compound
Ustalic acid is a naturally occurring chemical compound found in the poisonous mushroom Tricholoma ustale. The compound was first reported by Japanese
Ustalic_acid
Antiarrythmic agent
and then acylated with the acid chloride of phenylacetic acid to produce an amide. Selective hydrolysis with hydrobromic acid, followed by alkylation with
Lorcainide
Pharmaceutical compound
α-dideutero mescaline would be compromised by this conversion to the phenylacetic acid, but still could be valuable as a measure of the chiral position sensitivity
Beta-D
Pursuit of chemistry as a hobby
companies. In Canada, a wide range of basic laboratory reagents such as nitric acid and hydrogen peroxide are restricted as "explosives precursors". Two of the
Amateur_chemistry
Chemical compound
chlorobenzene 2 in presence of SnCl4 to afford 85% of the phenylacetic acid 3. Thereafter, the phenylacetic acid is treated with oxalyl chloride at room temperature
Chlorophacinone
Description of the structure and function of a genome
degradation of salicylate, benzoate, 4-hydroxybenzoate, phenylacetic acid, hydroxyphenyl acetic acid, and the recognition of an operon involved in glucose
DNA_annotation
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PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
PHENYLACETIC ACID
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