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Chemical data page
view edit Except where noted otherwise, data relate to Standard temperature and pressure. Reliability of data general note. ^a ^b ^c ^d ^e ^f ^g ^h CID
Phencyclidine_(data_page)
Dissociative hallucinogenic drug, mostly used recreationally
Phencyclidine or phenylcyclohexyl piperidine (PCP), also known in its use as a street drug as angel dust among other names, is a dissociative anesthetic
Phencyclidine
Class of psychoactive drugs
for abuse, unlike psychedelics. Despite some dissociatives, such as phencyclidine (PCP) possessing stimulating properties, most dissociatives seem to
Dissociative
Topics referred to by the same term
patients Phencyclidine, a hallucinogenic and dissociative recreational drug, also known as angel dust 3-HO-PCP, a designer drug related to phencyclidine 3-MeO-PCP
PCP
Cough suppressant and dissociative drug
other dissociative anesthetics such as ketamine, nitrous oxide, and phencyclidine. It was patented in 1949 and approved for medical use in 1953. In 2023
Dextromethorphan
Chemical compound
generic arylcyclohexylamine derivative, and a structural isomer of phencyclidine. 3-Methyl-PCP 3-HO-PCE BTCP Deoxymethoxetamine Ephenidine MDPCP Wallach
3-Methyl-PCPy
Chemical compound
to phencyclidine and has been sold online as a designer drug. It has been shown to have reinforcing effects in animal studies, although human data is
3-MeO-PCMo
Topics referred to by the same term
name for high-fidelity audio equipment Leak, a slang term for the drug phencyclidine (PCP) Leak, a slang term for urination Memory leak, incorrect allocation
Leak_(disambiguation)
Glutamate receptor and ion channel protein found in nerve cells
of the NMDA receptor is blocked by many psychoactive drugs such as phencyclidine (PCP), alcohol (ethanol) and dextromethorphan (DXM). The anaesthetic
NMDA_receptor
Chemical compound
α-Endopsychosin is a putative antagonist of the phencyclidine site of the NMDA receptor which was discovered in extracts of porcine brain and may also
Α-Endopsychosin
Chemical compound
recreational drug of the arylcyclohexylamine class which is related to phencyclidine (PCP). It was first described in a patent application naming Marc Caron
Benocyclidine
Dissociative anesthetic designer drug
Bruylants reaction similar to the one later employed in the discovery of phencyclidine in 1956. Following the 2013 UK ban on arylcyclohexylamines, diphenidine
Diphenidine
Pharmaceutical compound
Japan. Ketamir Shulgin AT, Mac Lean DE (1976). "Illicit synthesis of phencyclidine (PCP) and several of its analogs". Clinical Toxicology. 9 (4): 553–560
PCPEP
Chemical compound
hallucinogenic and stimulant effects. It is around the same potency as phencyclidine, although slightly less potent than the ethyl homologue eticyclidine
PCPr
Chemical compound
vitro and in vivo metabolism and detection of 3-HO-PCP, a synthetic phencyclidine, in human samples and pooled human hepatocytes using high resolution
3-HO-PCP
Chemical compound
the Sciences in Philadelphia. 3690548. Wallach J, Brandt SD (2018). "Phencyclidine-Based New Psychoactive Substances". New Psychoactive Substances. Handbook
MDPCP
Dissociative drug
designer drug. It differs from many dissociatives such as ketamine and phencyclidine (PCP) that were developed as pharmaceutical drugs for use as general
Methoxetamine
SNRI medication
predefined minimal clinically important differences. There was insufficient data to assess suicide or other serious adverse events. All results assessed were
Duloxetine
Designer drug combination mimicking MDMA
Retrieved 4 November 2025. DrugsData.org / Erowid (10 April 2024). "Pink Star, Result #13477". DrugsData.org (was EcstasyData). Erowid. Retrieved 4 November
Borax_combo
Chemical compound
Maddox VH, Godefroi EF, Parcell RF (March 1965). "The synthesis of phencyclidine and other 1-arylcyclohexylamines". Journal of Medicinal Chemistry. 8
3-Methyl-PCP
Chemical compound
affinity NMDA antagonist (IC50 = 0.51 μM). It is a structural analog of phencyclidine. It was first synthesized by a team at Parke-Davis in the late 1950s
NEFA_(drug)
Opioid receptor antagonist
"(+)-[3H]SKF 10,047, (+)-[3H]ethylketocyclazocine, mu, kappa, delta and phencyclidine binding sites in guinea pig brain membranes". European Journal of Pharmacology
Naloxone
Typical antipsychotic medication
drug-induced psychosis caused by ketamine,[unreliable medical source?] and phencyclidine, and psychosis associated with high fever or metabolic disease. Some
Haloperidol
Unpleasant experience triggered by psychoactive drugs
intoxication caused by LSD and other tryptamines, amphetamines, ketamine, and phencyclidine. Psychiatrist Stanislav Grof once said in an interview: There is a tremendous
Bad_trip
Medication
anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the
Eticyclidine
Pharmaceutical compound
agonist, enhancing amphetamine-induced hyperlocomotion, inhibiting phencyclidine (PCP)-induced hyperlocomotion, and restoring PCP-induced disruption
Nuciferine
Psychoactive substance found in plants in the family Apocynaceae
affinity for the NMDA receptor. However, the NMDA receptor antagonists phencyclidine (PCP) and dizocilpine (MK-801) fail to substitute for ibogaine and ibogaine
Ibogaine
Chemical compound
dissociative effects. It has potency in between that of ketamine and phencyclidine but with somewhat more sedating effects in animal studies. It has been
4-Keto-PCP
Pharmaceutical compound
negligible behavioral effects itself. Fourphit is an acylating derivative of phencyclidine (PCP) and a positional isomer of metaphit (3-isothiocyanato-PCP). RTI-76
Fourphit
CIA program involving illegal experimentation on human test subjects (1953–1972)
as radiation, blister and nerve agents, biological agents, LSD, and phencyclidine (PCP). These tests and experiments were conducted to support weapon
MKUltra
Chemical compound
Shannon HE (January 1984). "Structure-activity relationship studies of phencyclidine derivatives in rats". The Journal of Pharmacology and Experimental Therapeutics
3-Fluoro-PCP
Form of the drug cocaine
tobacco ("coolie"); marijuana ("turbbo"); heroin ("moon rock"); and phencyclidine ("spacebase"). This type of mixed-drug use is higher risk than single-drug
Crack_cocaine
Chemical compound
research chemical of the arylcyclohexylamine chemical class related to phencyclidine (PCP) and eticyclidine (PCE). It acts as an NMDA receptor antagonist
Dieticyclidine
Designer drug, analog of modafinil
Dieticyclidine Esketamine Eticyclidine Gacyclidine Ketamine Phencyclamine Phencyclidine Rolicyclidine Tenocyclidine Tiletamine Benzazepines 6-Br-APB SKF-77434
CE-123
Species of plant
other reviews note that kratom withdrawal itself can still be quite severe. Data on how widely it is used worldwide are lacking, as it is not detected by
Mitragyna_speciosa
Pharmaceutical compound
hyperlocomotion in female but not male mice, to not exacerbate phencyclidine (PCP)-induced hyperlocomotion, to not worsen dizocilpine (MK-801)-induced
JRT_(drug)
Pharmaceutical compound
is orally active. Ketamir-2 is a very low-affinity antagonist of the phencyclidine (PCP) site of the NMDA receptor. Its affinity (IC50Tooltip half-maximal
Ketamir-2
Chemical compound
patients reported side effects such as nightmares and hallucinations. Phencyclidine (PCP), tenocyclidine (TCP), etoxadrol and its precursor, dexoxadrol
Etoxadrol
SSRI antidepressant
group cognitive behavioral therapy is undergone or not. Limited pediatric data also demonstrates a reduction in depressive symptoms in the pediatric population
Sertraline
Chemical compound
synthesized in 1979 to investigate the structure–activity relationships of phencyclidine (PCP) derivatives. The effects of 3-MeO-PCP in humans were not described
3-MeO-PCP
American rapper and songwriter (born 1987)
recalled once trying marijuana, where the blunt had been laced with Phencyclidine (PCP), and he has not used any drugs since. In an interview with Starz
Kendrick_Lamar
Atypical opioid analgesic
McAninch J. 7-Hydroxymitragynine (7-OH): An Assessment of the Scientific Data and Toxicological Concerns Around an Emerging Opioid Threat (Report). "Federal
7-Hydroxymitragynine
Chemical compound
(25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before
Methoxmetamine
Pharmaceutical compound
4-MeO-PCP BDPC Dieticyclidine (PCDE) Eticyclidine (PCE) MDPCP PCPEP PCPr Phencyclidine (PCP) Rolicyclidine (PCPy) TCTHP Tenocyclidine (TCP) Others: Gacyclidine
Tilmetamine
US military chemical warfare research
anxiolytic which shows deliriant and hallucinogenic effects EA 2148-A - Phencyclidine (PCP) EA 2233 - A dimethylheptylpyran variant, a synthetic cannabanoid
Edgewood Arsenal human experiments
Edgewood_Arsenal_human_experiments
Investigational antipsychotic
prevented the hyperlocomotion induced by the NMDA receptor antagonist phencyclidine (PCP). Conversely, ulotaront did not affect dextroamphetamine-induced
Ulotaront
Drug that reduces excitement without inducing sleep
(Ketalar) Methoxyflurane (Penthrox) Nitrous oxide ("Laughing gas") Phencyclidine (PCP) Propofol (Diprivan) Sevoflurane (Sevorane) Xenon Methaqualone
Sedative
Chemical compound
heart rate and no significant effect on blood pressure. Hyperforin Phencyclidine Indatraline Dexanabinol Doggrell SA. "Tesofensine – a novel potent weight
Tesofensine
Chemical compound
Gannon BM, Fitzgerald LR, Carbonaro TM, Johnson CR, et al. (June 2024). "Phencyclidine-Like Abuse Liability and Psychosis-Like Neurocognitive Effects of Novel
3-Chloro-PCP
Chemical compound
and Loathing on the Campaign Trail '72. In the footnotes in chapter April, page 140, he says: "It was sometime after midnight in a ratty hotel room and my
Adrenochrome
Chemical compound
(25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before
MDPHP
Peptide hormone and neuropeptide
but not LSD, significantly increased plasma oxytocin concentrations. These data may help explain why pro-social effects are particularly pronounced during
Oxytocin
Pharmaceutical compound
Difemetorex Ethylphenidate HDMP-28 Methylphenidate Pethidine (meperidine) Phencyclidine Pipradrol Serdexmethylphenidate Tenocyclidine Pyrrolidines: Diphenylprolinol
Cendifensine
Chemical compound
Difemetorex Ethylphenidate HDMP-28 Methylphenidate Pethidine (meperidine) Phencyclidine Pipradrol Serdexmethylphenidate Tenocyclidine Pyrrolidines: Diphenylprolinol
Org_6582
banned substance in the U.K.). Unlike the other well-known dissociatives phencyclidine (PCP) and dextromethorphan (DXM), ketamine is very short-acting. It
Ketamine in society and culture
Ketamine_in_society_and_culture
Dissociative designer drug
novel dissociative drug of the arylcyclohexylamine class, related to phencyclidine. It was first identified as a novel psychoactive substance in Sweden
3-HO-PCE
Adulteration of drugs
include diphenhydramine, acetaminophen, 5-MeO-DiPT, 2C-B, procaine, and phencyclidine (PCP). Ecstasy pills sometimes contain dimethylamylamine to increase
Lacing_(drugs)
Pharmaceutical compound
rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia". Behavioural Brain Research. 454 114614
NU-1223
Sigma σ2 receptor ligand
Ketamine MDMA (midomafetamine) Methamphetamine OPC-14523 Opipramol PB-28 Phencyclidine Siramesine (Lu 28-179) UKH-1114 Antagonists: AC-927 BD-1008 BD-1067
Lu_29-252
Deadly nightshade, a flowering plant
projects: Media from Commons Quotations from Wikiquote Taxa from Wikispecies Data from Wikidata "Compounds in deadly nightshade". Phytochemical and Ethnobotanical
Atropa_bella-donna
Pharmaceutical compound
SDA Clinical data Other names 3-Thio-MDA; 3T-MDA; 3,4-Methylenethiooxyamphetamine Drug class Serotonin–norepinephrine–dopamine releasing agent; Serotonin
SDA_(drug)
Atypical antipsychotic medication
other atypical antipsychotics found it difficult to determine differences as data quality is poor. A 2011 Cochrane review comparing aripiprazole with placebo
Aripiprazole
Pharmaceutical compound
Dieticyclidine Esketamine Eticyclidine Gacyclidine Ketamine Phencyclamine Phencyclidine Rolicyclidine Tenocyclidine Tiletamine Benzazepines 6-Br-APB SKF-77434
N,N-Dipropyldimethocaine
Chemical compound
aineista" [Government decree on psychoactive substances banned from the consumer market]. Finlex Data Bank (in Finnish). Finnish Ministry of Justice. v t e
Methoxpropamine
Pharmaceutical compound
The Shulgin Index (The 23 homo-phenylethylamines compounds in table 10, page 358). Shulgin AT, Jacob P (March 1982). "1-(3,4-methylenedioxyphenyl)-3-aminobutane:
GAMMA_(drug)
Use of drugs with the primary intention to alter the state of consciousness
(see also the section below): tobacco, cannabis, opium, crystal meth, phencyclidine, crack cocaine, and heroin (diamorphine as freebase) known as chasing
Recreational_drug_use
SSRI antidepressant
mg/day dose of citalopram, which increased the QTc interval by 18.5 ms. More data about the cardiac risk from escitalopram can be found in a large observational
Escitalopram
Chemical compound
acetyltransferase production in the medial septal nucleus of rats exposed to phencyclidine (PCP), and is considered a potential therapeutic drug for schizophrenia
Coluracetam
Practice of humans eating other humans
Does PCP turn people into cannibals? (2005) – answers that while using phencyclidine occasionally turns people violent, only in the case of Antron Singleton
Human_cannibalism
Medication mainly used for depression and smoking cessation
sigma receptors in mouse brain with [ 3 H]-(+)-SKF 10,047: Effects of phencyclidine, (+)- and (−)-N-allylnormetazocine, and other drugs". Drug Development
Bupropion
Blue dye also used as a medication
controversial problem given the heterogeneity of available data and the lack of preclinical data, which is in conflict with standards of safe use of such
Methylene_blue
Chemical compound
journal}}: CS1 maint: periodical has ISBN (link) Erowid, DrugsData org /. "DrugsData.org (was EcstasyData): Test Details : Result #15191 - White Crystals, 15191"
Fluorexetamine
Antihistamine medication
Diphenhydramine Clinical data Pronunciation /ˌdaɪfɛnˈhaɪdrəmiːn/ Trade names Benadryl, others AHFS/Drugs.com Monograph MedlinePlus a682539 License data US DailyMed: Diphenhydramine
Diphenhydramine
Pharmaceutical compound
somniferum (opium) Pentazocine Pericine Pethidine (meperidine) Phenazocine Phencyclidine Piminodine Piritramide PL-017 Prodine Propiram PZM21 Racemethorphan
SR-15099
Pharmaceutical compound
somniferum (opium) Pentazocine Pericine Pethidine (meperidine) Phenazocine Phencyclidine Piminodine Piritramide PL-017 Prodine Propiram PZM21 Racemethorphan
R6372
New Psychoactive Substance Dissociative Eticyclidine Derivative
4-MeO-PCP BDPC Dieticyclidine (PCDE) Eticyclidine (PCE) MDPCP PCPEP PCPr Phencyclidine (PCP) Rolicyclidine (PCPy) TCTHP Tenocyclidine (TCP) Others: Gacyclidine
3-Me-PCE
Chemical compound
involved in the drug psychosis that can be induced by some drugs such as phencyclidine and cocaine, and rimcazole was originally researched as a potential
Rimcazole
Pharmaceutical compound
tenocyclidine itself and other related compounds such as ketamine and phencyclidine, TCTHP acts as an NMDA antagonist. While NMDA antagonists can be neurotoxic
TCTHP
Chemical compound
"The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor"
3-MeO-PCE
Pharmaceutical compound
locomotor activity by itself, but blocks the hyperlocomotion induced by phencyclidine (PCP). In addition, whereas meta-chlorophenylpiperazine (mCPP) produces
LY-53857
Pharmaceutical compound
Norquetiapine Clinical data Other names N-Desalkylquetiapine; NQTP Drug class Atypical antipsychotic ATC code N05AH02 (WHO) Identifiers IUPAC name
Norquetiapine
Chemical compound
social interaction deficits induced by the NMDA receptor antagonist phencyclidine (PCP). In contrast to serotonin 5-HT2A receptor agonists, DLX-2270 does
DLX-2270
Central nervous system stimulant
alcohol, cannabinoids, cocaine, methylphenidate, nicotine, opioids, phencyclidine, propofol, and substituted amphetamines, among others. ΔJunD, a transcription
Methamphetamine
Drug used to treat depressive and anxiety disorders
antidepressants and dextromethorphan bind with higher affinity to the phencyclidine receptor in the absence of magnesium and L-glutamate". Molecular Pharmacology
Opipramol
Pharmaceutical compound
found to reverse the hyperlocomotion induced by dizocilpine (MK801) and phencyclidine (PCP) in rodents. The pharmacokinetics of 11-chloroasimilobine have
11-Chloroasimilobine
Chemical compound
somniferum (opium) Pentazocine Pericine Pethidine (meperidine) Phenazocine Phencyclidine Piminodine Piritramide PL-017 Prodine Propiram PZM21 Racemethorphan
MGM-15
Chemical compound
two-compartment model for absorption and elimination best describes this data. However, at most, only 7% of the ingested cathinone is recovered in the
Cathinone
Experimental esketamine prodrug
4-MeO-PCP BDPC Dieticyclidine (PCDE) Eticyclidine (PCE) MDPCP PCPEP PCPr Phencyclidine (PCP) Rolicyclidine (PCPy) TCTHP Tenocyclidine (TCP) Others: Gacyclidine
XW10508
Chemical compound
Ketamine MDMA (midomafetamine) Methamphetamine OPC-14523 Opipramol PB-28 Phencyclidine Siramesine (Lu 28-179) UKH-1114 Antagonists: AC-927 BD-1008 BD-1067
Noscapine
Pharmaceutical compound
MDM1EA Clinical data Other names N-Methyl-1-(3,4-methylenedioxyphenyl)-1-ethanamine; MDM1EA; α,N-Dimethyl-3,4-methylenedioxybenzylamine; α,N-DMMDBA; α
MDM1EA
Pharmaceutical compound
(May 2022). "Dual 5-HT3 and 5-HT6 Receptor Antagonist FPPQ Normalizes Phencyclidine-Induced Disruption of Brain Oscillatory Activity in Rats". The International
FPPQ
Type of α-amino acid
5313600I. doi:10.1002/anie.201406886. PMID 25336255. Dawson RM, et al. (1959). Data for Biochemical Research. Oxford: Clarendon Press. "Nomenclature and Symbolism
Phenylalanine
Chemical compound
somniferum (opium) Pentazocine Pericine Pethidine (meperidine) Phenazocine Phencyclidine Piminodine Piritramide PL-017 Prodine Propiram PZM21 Racemethorphan
IC-26
Medication
Milsaperidone Clinical data Trade names Bysanti Other names VHX896, VHX-896 AHFS/Drugs.com Monograph MedlinePlus a626033 License data US DailyMed: Milsaperidone
Milsaperidone
Stimulant drug
Dieticyclidine Esketamine Eticyclidine Gacyclidine Ketamine Phencyclamine Phencyclidine Rolicyclidine Tenocyclidine Tiletamine Benzazepines 6-Br-APB SKF-77434
Bromantane
Chemical compound
Ephenidine Fluorolintane Lanicemine Lefetamine NMDA receptor antagonist Phencyclidine Morris H, Wallach J (July–August 2014). "From PCP to MXE: a comprehensive
Methoxphenidine
Chemical compound
somniferum (opium) Pentazocine Pericine Pethidine (meperidine) Phenazocine Phencyclidine Piminodine Piritramide PL-017 Prodine Propiram PZM21 Racemethorphan
MGM-16
Experimental antidepressant
Difemetorex Ethylphenidate HDMP-28 Methylphenidate Pethidine (meperidine) Phencyclidine Pipradrol Serdexmethylphenidate Tenocyclidine Pyrrolidines: Diphenylprolinol
Lafadofensine
Chemical compound
somniferum (opium) Pentazocine Pericine Pethidine (meperidine) Phenazocine Phencyclidine Piminodine Piritramide PL-017 Prodine Propiram PZM21 Racemethorphan
Semax
Chemical compound
4-MeO-PCP BDPC Dieticyclidine (PCDE) Eticyclidine (PCE) MDPCP PCPEP PCPr Phencyclidine (PCP) Rolicyclidine (PCPy) TCTHP Tenocyclidine (TCP) Others: Gacyclidine
Deoxymethoxetamine
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