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Species of bacterium
glycosylates Rho and Ras GTPases, disrupting host cell signaling. Perfringolysin O (PFO) is a pore-forming haemolytic toxin belonging to the cholesterol-dependent
Clostridium_perfringens
Perfringolysin O (PFO), historically known as theta toxin, is cholesterol-dependent cytolysin (CDC) produced by many strains of Clostridium perfringens
Perfringolysin_O
Toxin produced by microorganisms
producing toxins relating to the cause of diseases. The pore-forming toxin perfringolysin has the ability to cause gangrene in calves with the presence of alpha
Microbial_toxin
Family of toxins from bacteria
recognition. Single amino acid modifications in these loops prevented perfringolysin O (PFO; TC# 1.C.12.1.1), which is a CDC secreted by Clostridium perfringens
Cholesterol-dependent cytolysin
Cholesterol-dependent_cytolysin
Membrane-bound extracellular vesicles
microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O". The Journal of Histochemistry and Cytochemistry. 50 (1): 43–55. doi:10
Exosome_(vesicle)
Toxin from bacteria that destroys or disrupts cells
pneumoniae Pneumolysin, Clostridium perfringens perfringolysin O, and Listeria monocytogenes listeriolysin O cause specific modifications of histones in the
Exotoxin
Substances toxic to individual cells
also been surveyed. Rossjohn et al. present the crystal structure of perfringolysin O, a thiol-activated cytolysin, which creates membrane holes on eukaryotic
Cytolysin
Large group of transport proteins
Figure 1: a) The structure of the CDC perfringolysin O [1] and b) the structure of Plu-MACPF [2]. In both proteins the two small clusters of α-helicesl
MACPF
Protein-produced toxins that create pores in cell membrane
highly conserved cholesterol-dependent cytolysins, closely related to perfringolysin from Clostridium perfringens are produced by bacteria from across the
Pore-forming_toxin
Dutch chemist and physicist specialized in photochemistry
used to measure the direct interaction of pore-forming toxins such as perfringolysin O and aerolysin with liposomes. By investigating aqueous solutions, she
Sylvie_Roke
Membrane proteins that adhere temporarily to membranes with which they are associated
on 2007-09-29. Retrieved 2007-01-25. Casale, Jarett; Kacimi, Salah Eddine O.; Varacallo, Matthew (2023), "Biochemistry, Phospholipase A2", StatPearls
Peripheral_membrane_protein
PERFRINGOLYSIN O
PERFRINGOLYSIN O
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Surname or Lastname
English and Scottish (of Norman origin) and French
English and Scottish (of Norman origin) and French : habitational name from any of various places in northern France which get their names from the Gallo-Roman personal name Maccius + the locative suffix -acum.English (of Norman origin) : habitational name from Marcy in La Manche. This surname is preserved in the English place name Stondon Massey.English : from a pet form of Matthew.Altered spelling of French Massé (see Masse 4).
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Surname or Lastname
English and Irish (of Norman origin)
English and Irish (of Norman origin) : nickname from Old French mau ‘bad’ + clerc ‘cleric’.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : habitational name from Marigni in La Manche, so called from the Gallo-Roman personal name Marinius + the locative suffix -acum.
Surname or Lastname
English or Irish
English or Irish : unexplained. Perhaps an Anglicized form of Gaelic Mac Thom ‘son of Tom’.
Surname or Lastname
English (Oxfordshire)
English (Oxfordshire) : from a personal name based on Old French Otuel.
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Surname or Lastname
English (Devon; of Cornish origin)
English (Devon; of Cornish origin) : topographic name for someone who lived by a menhir, i.e. a tall standing stone erected in prehistoric times (Cornish men ‘stone’ + hir ‘long’).
Surname or Lastname
English (Suffolk) of uncertain derivation;
English (Suffolk) of uncertain derivation; : of uncertain derivation; perhaps from a reduced form of the personal name Dominicus (see Dominick).English (Suffolk) of uncertain derivation; : alternatively, as Reaney proposes, it may be from the Breton personal name Menguy, a compound of men ‘stone’ + ki ‘dog’.
Surname or Lastname
Altered spelling of French Minot, written thus to preserve the final -t, which is pronounced in Canadian French.English
Altered spelling of French Minot, written thus to preserve the final -t, which is pronounced in Canadian French.English : variant of Minett.
Surname or Lastname
Americanized form of German Möller (see Moeller).German
Americanized form of German Möller (see Moeller).German : habitational name for someone from Melle.German, Jewish (Ashkenazic), and Polish : occupational name for a miller or flour merchant, from an agent derivative of German Mehl ‘flour’.English : variant of Miller.
Surname or Lastname
English or Scottish
English or Scottish : unexplained.German and Dutch : probably a variant of Maske.
Surname or Lastname
Variant spelling of German Mentzer, a habitational name for someone from a place called Mentz (possibly Mainz) or Menz.English
Variant spelling of German Mentzer, a habitational name for someone from a place called Mentz (possibly Mainz) or Menz.English : probably a variant of Manser. Compare Menser.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : from a derivative of the Continental Germanic personal name Maginhari, composed of the elements magin ‘strength’, ‘might’ + hari ‘army’.
Surname or Lastname
English (of Norman origin) and French
English (of Norman origin) and French : from the Continental Germanic personal name Mainard, composed of the elements magin ‘strength’ + hard ‘hardy’, ‘brave’, ‘strong’.
Surname or Lastname
English and Irish (of Norman origin)
English and Irish (of Norman origin) : nickname for a thin person, from Old French maigre ‘thin’, ‘slender’ (Latin macer ‘delicate’).
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddock.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : via Old French from the Germanic personal name Milo, of unknown etymology. The name was introduced to England by the Normans in the form Miles (oblique case Milon). In English documents of the Middle Ages the name sometimes appears in the Latinized form Milo (genitive Milonis), although the normal Middle English form was Mile, so the final -s must usually represent the possessive ending, i.e. ‘son or servant of Mile’.English : patronymic from the medieval personal name Mihel, an Old French contracted form of Michael.English : occupational name for a servant or retainer, from Latin miles ‘soldier’, sometimes used as a technical term in this sense in medieval documents.Irish (County Mayo) : when not the same as 1 or 3, an Anglicized form of Gaelic Ó Maolmhuire, Myles being used as the English equivalent of the Gaelic personal name Maol Muire (see Mullery).Jewish (eastern Ashkenazic) : unexplained.Dutch : variant of Miels, a variant of Miele 3.John Miles or Myles (c.1621–83), born probably in Herefordshire, England, was a pioneer American Baptist minister who emigrated to New England in 1662 and had a pastorate in Swansea, MA. Many of his descendants spell their name Myles.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : occupational name for a goldsmith, from Anglo-Norman French orfrer, Old French orfevre, Latin aurifaber, from aurum ‘gold’ + faber ‘maker’. Compare French Fèvre (see Lefevre).German : variant of Off.Jewish : unexplained.
PERFRINGOLYSIN O
PERFRINGOLYSIN O
Female
English
Variant spelling of English Earline, EARLENE means "nobleman, prince, warrior."
Boy/Male
Hindu, Indian, Marathi
A King
Girl/Female
Gaelic
Spear.
Boy/Male
Tamil
Sai Karthik | ஸாஈ காரà¯à®¤à®¿à®•
Flower
Boy/Male
Indian
Handsome, Healthy
Boy/Male
Australian, French, Greek, Latin
Masculine
Female
Spanish
Feminine form of Spanish Teófilo, TEÓFILA means "God's friend."
Boy/Male
Hindu
Bron from a good family, Well-born
Boy/Male
Australian, Dutch, Italian
Italian Form of Bertrand; Brilliant Raven; Fiery Torch; Beacon
Boy/Male
Australian, Romanian
Worker
PERFRINGOLYSIN O
PERFRINGOLYSIN O
PERFRINGOLYSIN O
PERFRINGOLYSIN O
PERFRINGOLYSIN O
imp., p. p., or auxi
To be bound in duty or by moral obligation.
n.
A yellow, earthy incrustation, consisting essentially of the oxide of uranium, but more or less impure.
n.
Alt. of Uran-ochre
n.
A short side track on a railroad, which may be occupied by one train while another is passing on a main track; a shunt; a siding; a switch.
imp., p. p., or auxi
Was or were under obligation to pay; owed.
n.
Net quantity of produce yielded.
imp., p. p., or auxi
Owned; possessed.
interj., adv., or a.
A word of unknown origin and signification, formerly used as expressive of contempt, or when anything said was reject as trifling or impertinent.
obs.
imp. of Tide, v. i.
pl.
of Turn-out
n.
That which is prominently brought forward or exhibited; hence, an equipage; as, a man with a showy carriage and horses is said to have a fine turn-out.
n.
In racing, the going over a course by a horse which has no competitor for the prize; hence, colloquially, a one-sided contest; an uncontested, or an easy, victory.
a.
Containing or exhibiting positive, or vitreous, electricity.
imp., p. p., or auxi
To be necessary, fit, becoming, or expedient; to behoove; -- in this sense formerly sometimes used impersonally or without a subject expressed.
n.
The aggregate number of persons who have come out, as from their houses, for a special purpose.
n.
The act of coming forth; a leaving of houses, shops, etc.; esp., a quitting of employment for the purpose of forcing increase of wages; a strike; -- opposed to lockout.