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Symptoms resulting from kidney damage
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and
Nephrotic_syndrome
Medical condition
Congenital nephrotic syndrome is a rare kidney disease which manifests in infants during the first 3 months of life, and is characterized by high levels
Congenital_nephrotic_syndrome
Kidney disorder
Childhood-onset nephrotic syndrome is a kidney disorder characterized by severe proteinuria (excess proteins in the urine), hypoalbuminemia (low albumin
Childhood-onset nephrotic syndrome
Childhood-onset_nephrotic_syndrome
Kidney disease causing nephrotic syndrome
others, is a disease affecting the kidneys which causes nephrotic syndrome. Nephrotic syndrome leads to the loss of significant amounts of protein to the
Minimal_change_disease
Term for several kidney diseases
inflammation typically results in one or both of the nephrotic or nephritic syndromes. The nephrotic syndrome is characterised by the finding of edema in a person
Glomerulonephritis
Symptoms resulting from kidney inflammation
symptoms that specifically do not include hematuria. Nephritic syndrome, like nephrotic syndrome, may involve low level of albumin in the blood due to the
Nephritic_syndrome
Accumulation of excess fluid in tissue
pressure occurs in cardiac failure. A fall in osmotic pressure occurs in nephrotic syndrome and liver failure. Causes of edema that are generalized to the whole
Edema
Abnormally low levels of albumin in the blood
result of severe anorexia nervosa, sepsis, cirrhosis in the liver, nephrotic syndrome in the kidneys, or protein-losing enteropathy in the gastrointestinal
Hypoalbuminemia
Medical condition
syndrome is a very rare autosomal recessive genetic disorder, consisting of a variety of features including hiatal hernia, microcephaly and nephrotic
Galloway–Mowat_syndrome
Kidney disease
nephrotic syndrome in adults, with focal segmental glomerulosclerosis (FSGS) recently becoming the most common. Most people will present as nephrotic
Membranous_glomerulonephritis
Syndromes
myasthenic syndrome Congenital nephrotic syndrome Congenital rubella syndrome Conn's syndrome Conorenal syndrome Conradi–Hünermann syndrome Constriction
List_of_syndromes
Kidney disease
due to protein loss. FSGS is a leading cause of excess protein loss—nephrotic syndrome—in children and adults in the US. Signs and symptoms include proteinuria
Focal segmental glomerulosclerosis
Focal_segmental_glomerulosclerosis
Disease typically found in young children
Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children
Kawasaki_disease
Medical condition
blood clotting abnormalities or dehydration and adults with nephrotic syndrome. Nephrotic syndrome, a kidney disorder, causes excessive loss of protein in
Renal_vein_thrombosis
Cylindrical protein structure in urine in certain disease states
product of a dilated duct, and are seen in chronic kidney failure. In nephrotic syndrome, many additional types of casts exist, including broad and waxy casts
Urinary_cast
Medical condition
clinical presentation of MesPGN usually consists of hematuria or nephrotic syndrome. Treatment is often consistent with the histologic pattern of and
Mesangial proliferative glomerulonephritis
Mesangial_proliferative_glomerulonephritis
Disease where the kidneys fail to adequately filter waste products from the blood
breakdown, and hemolytic uremic syndrome. Causes of chronic kidney failure include diabetes, high blood pressure, nephrotic syndrome, and polycystic kidney disease
Kidney_failure
Protein-coding gene in the species Homo sapiens
resistant nephrotic syndrome. A1BG was present in 7/19 patients with SRNS and was absent from all patients with steroid sensitive nephrotic syndrome. The 13
Alpha-1-B_glycoprotein
Medical condition
Imune Syndrome (RENI), or Nephrotic Syndrome, type 14 (NPHS14). This disease can cause a variety of symptoms, including steroid-resistant nephrotic syndrome
Sphingosine phosphate lyase insufficiency syndrome
Sphingosine_phosphate_lyase_insufficiency_syndrome
Large plasma protein found in the blood
The concentration of α2-macroglobulin rises 10-fold or more in the nephrotic syndrome when other lower molecular weight proteins are lost in the urine.
Alpha-2-Macroglobulin
Mammalian protein found in Homo sapiens
defect in the gene for nephrin, NPHS1, is associated with congenital nephrotic syndrome of the Finnish type and causes massive amounts of protein to be leaked
Nephrin
Presence of an excess of serum proteins in the urine
also be caused by other conditions). Severe proteinuria can cause nephrotic syndrome in which there is worsening swelling of the body. Proteinuria often
Proteinuria
Disease characterized by hypoparathyroidism, sensorineural deafness and renal disease
may range from mild to profound impairment. Renal disease includes nephrotic syndrome, cystic kidney, renal dysplasia, hypoplasia or aplasia, pelvicalyceal
Barakat_syndrome
Type of kidney cell
currently 53 genes known to play a role in genetic nephrotic syndrome. In idiopathic nephrotic syndrome, there is no known genetic mutation. It is thought
Podocyte
Laboratory test
in nephrotic syndrome. Increased AMG is also noted in rats with no albumin indicating that this is a response to low albumin rather than nephrotic syndrome
Serum_protein_electrophoresis
Biochemical cofactor and antioxidant
mutations in COQ6, can lead to serious diseases such as steroid-resistant nephrotic syndrome with sensorineural deafness. Although CoQ10 may be measured in blood
Coenzyme_Q10
Medical condition
trauma, AIDS, chemotherapy), or in hypoalbuminemic states such as the nephrotic syndrome or dietary protein deficiency. They are also seen in people with end-stage
Muehrcke's_nails
Fluid-filled space between the lungs
effusions occur in congestive heart failure (CHF), cirrhosis, or nephrotic syndrome. Localized pleural fluid effusion noted during pulmonary embolism
Pleural_cavity
Abnormally elevated levels of lipids or lipoproteins in the blood
to acquired hyperlipidemia include: Hypothyroidism Kidney failure Nephrotic syndrome Alcohol consumption Some rare endocrine disorders and metabolic disorders
Hyperlipidemia
Organ of the urinary system
addresses diseases of kidney function: these include CKD, nephritic and nephrotic syndromes, acute kidney injury, and pyelonephritis. Urology addresses diseases
Kidney
Presence of lipids in the urine
of lipids in the urine. Lipiduria is most frequently observed in nephrotic syndrome where it is passed as lipoproteins along with other proteins. It has
Lipiduria
Diuretics that act along the loop of Henle in the kidneys
Volume overload associated with liver cirrhosis, heart failure, or nephrotic syndrome Cerebral edema - intravenous furosemide can be combined with mannitol
Loop_diuretic
New Zealand rugby union player (1975–2015)
IRB Hall of Fame on 24 October 2011. In 1995 he was diagnosed with nephrotic syndrome, a genetic kidney disorder. After a period of hiatus, he returned
Jonah_Lomu
Medical condition
presentation of AA amyloidosis is renal in nature, including proteinuria, nephrotic syndrome and progressive development of chronic kidney disease leading to end
AA_amyloidosis
Accumulation of excess fluid in the pleural cavity
hydrothorax Severe hypoalbuminemia Nephrotic syndrome Acute atelectasis Myxedema Peritoneal dialysis Meigs's syndrome Obstructive uropathy End-stage kidney
Pleural_effusion
Protein in the extracellular matrix
(junctional epidermolysis bullosa), and/or defects of the kidney filter (nephrotic syndrome). In humans, fifteen laminin trimers have been identified. The laminins
Laminin
Metabolic disease involving abnormal deposited amyloid proteins
(proteinuria) and nephrotic syndrome. Several types of amyloidosis, including the AL and AA types, are associated with nephrotic syndrome. Approximately
Amyloidosis
Loop diuretic medication
Furosemide is also used for liver cirrhosis, kidney impairment, nephrotic syndrome, in adjunct therapy for swelling of the brain or lungs where rapid
Furosemide
Medication used as chemotherapy and to suppress the immune system
neuroblastoma, and sarcoma. As an immune suppressor it is used in nephrotic syndrome, ANCA-associated vasculitis, and following organ transplant, among
Cyclophosphamide
glomerulonephritis 580.9 Glomerulonephritis, acute, unspec. 581 Nephrotic syndrome 581.9 Nephrotic syndrome, unspec. 582 Chronic glomerulonephritis 582.9 Glomerulonephritis
List of ICD-9 codes 580–629: diseases of the genitourinary system
List_of_ICD-9_codes_580–629:_diseases_of_the_genitourinary_system
Skin discoloration caused by carotenoids
carotenoderma include hypothyroidism, diabetes mellitus, anorexia nervosa, nephrotic syndrome, and liver disease. In hypothyroidism and diabetes mellitus, the underlying
Carotenosis
Medical condition
loss of albumin) occurs, with a resultant edema as would occur in nephrotic syndrome. Other major symptoms are bilateral pitting edema of extremities,
Epidemic_dropsy
Medical condition
sclerosis, and Wilms' tumor. The condition first manifests as early nephrotic syndrome and progresses to mesangial renal sclerosis, and ultimately kidney
Denys–Drash_syndrome
Medical condition
glomerular proteinuria (present in as many as 30%) and, in some, the nephrotic syndrome. Co-inheritance of microdeletions in the -globin gene (thalassemia)
Sickle_cell_nephropathy
Stiffening of a tissue or anatomical feature
filtering system (glomeruli) causing serious scarring and thus a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney
Sclerosis_(medicine)
Abnormal build-up of fluid in the abdomen
or spontaneous bacterial peritonitis Pancreatitis – 1% Serositis Nephrotic syndrome Hereditary angioedema Routine complete blood count (CBC), basic metabolic
Ascites
Inflammation of the kidneys
this case, lupus nephritis) is 28.4 years old. Nephrotic syndrome Bright's disease Goodpasture syndrome "Glomerulonephritis: MedlinePlus Medical Encyclopedia"
Nephritis
Formation of a blood clot in a deep vein
thrombocytopenia, catastrophic antiphospholipid syndrome, paroxysmal nocturnal hemoglobinuria, nephrotic syndrome, chronic kidney disease, polycythemia vera
Deep_vein_thrombosis
Chemical compound
intravenously for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, eczema, and in organ transplants to prevent rejection. It is also
Ciclosporin
Medical condition
dysgenesis), females are usually given the diagnosis of isolated nephrotic syndrome. Frasier syndrome in some infants may therefore go unrecognized until the affected
Frasier_syndrome
Non-inflammatory kidney disease
set of signs called the nephrotic syndrome. Nephrosis can be a primary disorder or can be secondary to another disorder. Nephrotic complications of another
Nephrosis
Pathological conditions of the kidney, impairing the organ's ability to filter blood
glomerulonephritis, can be further divided into the nephritic and nephrotic syndromes, which are respectively characterized by blood and protein leaking
Kidney_disease
Abnormal accumulation of fluid in the pericardial cavity of the heart
dissection Reduced lymphatic drainage: congestive heart failure, nephrotic syndrome How much fluid is stored in the pericardial sac at one particular
Pericardial_effusion
Severe swelling throughout the body
heart failure Severe protein deficiency Nephrotic syndrome Protein-losing enteropathies Capillary leak syndrome In Hb Barts, the high oxygen affinity results
Anasarca
Type of globular protein produced by the liver
A defect in this property results in nephrotic syndrome leading to albumin loss in the urine. Nephrotic syndrome patients are sometimes given albumin
Serum_albumin
Steroid medication
hives, eczema, lipid pneumonitis, pericarditis, multiple sclerosis, nephrotic syndrome, sarcoidosis, to relieve the effects of shingles, lupus, myasthenia
Prednisone
Medical condition
complication of cirrhosis of the liver. It can also occur in patients with nephrotic syndrome. SBP has a high mortality rate. The diagnosis of SBP requires paracentesis
Spontaneous bacterial peritonitis
Spontaneous_bacterial_peritonitis
Monosaccharide sugar
Quérin S (September 2009). "FSGS permeability factor-associated nephrotic syndrome: remission after oral galactose therapy". Nephrology, Dialysis, Transplantation
Galactose
Thiazide-like diuretic drug
pressure, swelling (such as occurs in heart failure, liver failure, and nephrotic syndrome), diabetes insipidus, and renal tubular acidosis. Because chlortalidone
Chlortalidone
Disease of the kidney
have minimal change disease on light microscopy and clinically have nephrotic syndrome, show an exquisite response to corticosteroids, behaving more or less
IgA_nephropathy
Abnormal kidney structure or gradual loss of kidney function
kidney length on the US image is illustrated by '+' and a dashed line. Nephrotic syndrome. Hyperechoic kidney without demarcation of cortex and medulla. Chronic
Chronic_kidney_disease
Chemical compound
be used in kidney disease, such as chronic kidney disease or the nephrotic syndrome. Chronic kidney disease causes excess fluid retention that is often
Metolazone
Abnormality of blood coagulation increasing the risk of blood clotting (thrombosis)
catheters for chemotherapy) may increase the risk of thrombosis further. Nephrotic syndrome, in which protein from the bloodstream is released into the urine
Thrombophilia
Indications of a specific illness, including psychiatric
syndrome. Noonan syndrome for example, has a diagnostic set of unique facial and musculoskeletal features. Some syndromes such as nephrotic syndrome may
Signs_and_symptoms
Group of autoimmune diseases resulting in abnormal growth of connective tissue
One form of the condition, known as CREST syndrome, classically results in calcium deposits, Raynaud's syndrome, esophageal problems, thickening of the
Scleroderma
kidney glomerulus. Mutations in the podocin gene NPHS2 can cause nephrotic syndrome, such as focal segmental glomerulosclerosis (FSGS) or minimal change
Podocin
Medication
remission in children with steroid-dependent or frequently relapsing nephrotic syndrome. This effect is particularly shown in children who have rituximab
Obinutuzumab
Inflammation of the kidneys
presence of red blood cell casts, red blood cells and proteinuria however a nephrotic picture may also be seen depending on the classification of lupus nephritis
Lupus_nephritis
German-American physician and nephrology researcher
multiple kidney diseases caused by single-genes (Mendelian) including nephrotic syndrome, cystic renal ciliopathies, and congenital anomalies of the kidney
Friedhelm_Hildebrandt
Tissue type
Peritonitis: Inflammation of the peritoneal lining due to infection. Nephrotic syndrome: Altered filtration in the kidneys affecting protein levels in urine
Simple_squamous_epithelium
Medical condition
insufficiency, proteinuria and these symptoms are often accompanied by nephrotic syndrome, but patients may also present with acute renal failure. 83% of MIDD
Monoclonal immunoglobulin deposition disease
Monoclonal_immunoglobulin_deposition_disease
Medication used to treat hypertension and heart failure
ISBN 978-0-07-176401-8. Reddi A (2018). "Disorders of ECF Volume: Nephrotic Syndrome". Fluid, Electrolyte and Acid-Base Disorders. Springer. ISBN 978-3-319-60167-0
Lisinopril
Condition in which the jaw is small
pseudo-hydrocephalic progeroid syndrome Nephrotic syndrome, type 11 Nestor-Guillermo progeria syndrome Neu–Laxova syndrome 1 and 2 Neuropathy, congenital
Micrognathism
Type of blood and immune-system cancer
However, there is debate as to whether the P-E fever truly exists. Nephrotic syndrome can occur in individuals with Hodgkin lymphoma and is most commonly
Hodgkin_lymphoma
Medical condition
Cushing's disease, hemolytic anemia, limbic encephalopathy, myocarditis, nephrotic syndrome, panhypopituitarism, pernicious anemia, polymyositis, rheumatoid arthritis
Thymoma
Human disease from a bacterial infection of the skin
edema Lymphatic obstruction Lymphoedema Nasopharyngeal infection Nephrotic syndrome Pregnancy Previous episode(s) of erysipelas Toe web intertrigo Traumatic
Erysipelas
Species of legume
other kidney diseases and Nephrotic Syndromes (NS). Reduced blood urea nitrogen and creatinine levels in nephrotic syndrome mouse indicated that Glycine
Glycine_tabacina
Type of connective tissue in animals
are usually sites that undergo oedema, indicating kidney failure or nephrotic syndrome. Therefore, periorbital swelling is one characteristic finding in
Loose_connective_tissue
White spots on finger and toe nails
clinical sign of hypoalbuminaemia (low albumin), which can be seen in nephrotic syndrome (a form of kidney failure), liver failure, protein malabsorption and
Leukonychia
Removal of fluids/air from the pleural cavity of the lungs
vs Constrictive pericarditis Transudate Congestive heart failure Nephrotic syndrome Hypoalbuminemia Cirrhosis Atelectasis Trapped lung Peritoneal dialysis
Thoracentesis
Pharmaceutical drug
also been reported rarely. Patients with hypothyroidism, diabetes, nephrotic syndrome, dysproteinemia, obstructive liver disease, kidney disease, or alcoholism
Colestyramine
Medical condition
as seen in nephrotic syndrome when a renal vein thrombosis embolizes to the lungs. Cardiogenic shock can mimic a pulmonary renal syndrome and lead to
Pulmonary-renal_syndrome
Chemical compound
inflammation; sarcoidosis in the lungs; and to treat edema in certain nephrotic syndromes. In the UK tetracosactide is used for short-term therapy in conditions
Adrenocorticotropic hormone (medication)
Adrenocorticotropic_hormone_(medication)
Chemical compound
treatment of cancer. It has also shown some efficacy in the treatment of nephrotic syndrome in children. After being pulled from the market in the US and Canada
Levamisole
Low sodium concentration in the blood
to hyponatremia. Cirrhosis of the liver Congestive heart failure Nephrotic syndrome in the kidneys Excessive water consumption (Water intoxication) There
Hyponatremia
British paediatrician and professor
kidney diseases., and for research into childhood Nephrotic syndrome and Hemolytic-uremic syndrome. Barratt's father owned and ran a law firm, and his
Martin_Barratt
American baseball executive
dedicated to raising funds and awareness for kidney diseases, including Nephrotic Syndrome and Focal Segmental Glomerulosclerosis (FSGS), conditions that his
Jim_Duquette
Blockage of an artery in the lungs
plasminogen/fibrinolysis disorders) Acquired thrombophilia (antiphospholipid syndrome, nephrotic syndrome, paroxysmal nocturnal hemoglobinuria) Cancer (due to secretion
Pulmonary_embolism
Group of autosomal recessive genetic disorders that affect Finns much more frequently
dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 3 Nephrotic syndrome, type 1 (Finnish congenital nephrosis) Ovarian dysgenesis 1 Polycystic
Finnish_heritage_disease
Formation of blood clots inside the blood vessels
otherwise healthy people. Men are affected more than women. Budd-Chiari syndrome is the blockage of a hepatic vein or of the hepatic part of the inferior
Thrombosis
Medical condition
the blood (hypoalbuminemia), heart failure, renal insufficiency, or nephrotic syndrome), conditions that place increased stress on the respiratory system
Transfusion-associated circulatory overload
Transfusion-associated_circulatory_overload
Medical condition
glomeruli. MPGN accounts for approximately 4% of primary renal causes of nephrotic syndrome in children and 7% in adults. It should not be confused with membranous
Membranoproliferative glomerulonephritis
Membranoproliferative_glomerulonephritis
High protein concentration in the blood
production (hypogammaglobulinemia), as well as increased protein loss (nephrotic syndrome, protein-losing enteropathy), can cause hypoproteinemia. To determine
Hyperproteinemia
Low protein concentration in the blood
decreasing synthesis of plasma proteins like albumin. Renal disease like nephrotic syndrome can also result in hypoproteinemia because plasma proteins are lost
Hypoproteinemia
Abnormal presence of albumin in the urine
swelling of the ankles, hands, belly or face may occur (see edema and nephrotic syndrome). This is because a major role of albumin in the blood is to act as
Albuminuria
Immunosuppressive drug
has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis
Mizoribine
Three factors thought to cause internal blood clots (thrombosis)
mutation, deficiency of antithrombin III, protein C or S deficiency, nephrotic syndrome, changes after severe trauma or burn, cancer, late pregnancy and delivery
Virchow's_triad
malformation Nephrosis neuronal dysmigration syndrome Nephrotic syndrome Nephrotic syndrome ocular anomalies Nephrotic syndrome, idiopathic, steroid-resistant Nerve
List_of_diseases_(N)
Inflammatory disease of the kidney
(nephrosis) presenting primarily in the glomerulus (a glomerulopathy) as nephrotic syndrome. The nephron is the functional unit of the kidney and it contains
Glomerulonephrosis
Russian and Soviet author (1891–1940)
constantly on duty at his bedside. On 10 March 1940, Bulgakov died from nephrotic syndrome (an inherited kidney disorder). His father had died of the same disease
Mikhail_Bulgakov
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