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Medical condition
People with lupus erythematosus are more likely to develop a lupus anticoagulant than the general population. The term "anticoagulant" accurately describes
Lupus_anticoagulant
Immune disorder leading to increased risk of blood clots
blood test results spaced at least three months apart that detect lupus anticoagulant, anti-apolipoprotein antibodies, and/or anti-cardiolipin antibodies
Antiphospholipid_syndrome
Autoimmune disease in which the immune system attacks healthy tissue
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue
Lupus
Laboratory test
venom time (dRVVT) is a laboratory test often used for detection of lupus anticoagulant (LA). It is an assessment of the time for blood to clot in the presence
Dilute Russell's viper venom time
Dilute_Russell's_viper_venom_time
Medical diagnostic method
test to detect lupus anticoagulants. There is evidence that suggests it is the most sensitive test for detecting lupus anticoagulants. It can also detect
Kaolin_clotting_time
antibodies and lupus anticoagulant. These antibodies are involved in sclerosis and are strongly associated with thrombotic forms of lupus. As a result,
Anti-apolipoprotein antibodies
Anti-apolipoprotein_antibodies
Type of blood plasma screening test
distinguish factor deficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against
Mixing_study
Blood test that evaluates clotting
prothrombin complex concentrate (PCC), or fresh frozen plasma (FFP). Lupus anticoagulant, a circulating inhibitor predisposing for thrombosis, may skew PT
Prothrombin_time
Health issue
anticoagulant (the RVVT and sensitive PTT are the best screening battery) and anticardiolipin antibodies. Neonatal lupus is the occurrence of lupus symptoms
Lupus_and_pregnancy
Medical condition
phlegmasia cerulea dolens with concurrent cholangiocarcinoma and a lupus anticoagulant: a case report and review of the literature". Blood Coagulation &
Phlegmasia_cerulea_dolens
Medical condition
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and
Childhood-onset systemic lupus erythematosus
Childhood-onset_systemic_lupus_erythematosus
Fluid found in the cavities of synovial joints
Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 978-0-7817-7153-5. "Lupus Anticoagulant". Family Practice Notebook. Archived from the original on 18 January
Synovial_fluid
Species of venomous snake
dRVVT test is more sensitive than the aPTT test for the detection of lupus anticoagulant (an antibody associated with antiphospholipid syndrome), because
Russell's_viper
Topics referred to by the same term
Linoleic acid, a fatty acid Lipoic acid, an organosulfur compound Lupus anticoagulant, an autoimmune disorder Local anesthetic, in medicine Ludwig's angina
La
Abnormality of blood coagulation increasing the risk of blood clotting (thrombosis)
constituents of the cell membrane, particularly lupus anticoagulant (first found in people with the disease systemic lupus erythematosus but often detected in people
Thrombophilia
Medical condition
deficiency Antiphospholipid antibodies Anticardiolipin antibodies Lupus anticoagulant Thrombocytosis Subclavian steal syndrome Malignant hypertension can
Amaurosis_fugax
Medical disorders that destroy blood vessels by inflammation
Susca, Nicola; Ingravallo, Giuseppe; Racanelli, Vito (5 November 2021). "Lupus Vasculitis: An Overview". Biomedicines. 9 (11). MDPI AG: 1626. doi:10
Vasculitis
Toxins that destroy red blood cells
Haemotoxins are used in diagnostic studies of the coagulation system. Lupus anticoagulant is detected by changes in the dilute Russell's viper venom time,
Hemotoxin
Inflammation of the cerebrum
inflammation of the brain tissue. It is commonly found in patients with lupus. Lupus cerebritis may occur in adults and children. The duration of the central
Cerebritis
Chemical compound
the coagulopathy. Lupus anticoagulant studies were negative. Superwarfarin toxicity was suspected and confirmed with an anticoagulant poison panel positive
Brodifacoum
Laboratory test
with warfarin or the presence of phospholipid-dependent anticoagulants, such as lupus anticoagulant. Thus, the ECT is prolonged in a specific and linear
Ecarin_clotting_time
Medical condition
differential diagnosis, one must consider: haemophilia A, haemophilia B, lupus anticoagulant and heparin contamination. The prolongation of the activated partial
Haemophilia_C
Medical laboratory instrument
(and the calculated INRs commonly used for therapeutic evaluation), Lupus anticoagulant screens, D dimer assays, and factor assays. Coagulometers require
Automated_analyser
Medical condition
to clot and how fast it takes to clot, indicating the presence of lupus anticoagulant in the blood. An enzyme-linked immunosorbent assay (ELISA) test is
Catastrophic antiphospholipid syndrome
Catastrophic_antiphospholipid_syndrome
Medical condition
Thrombin levels increase. Protein S, an anticoagulant, decreases. However, the other major anticoagulants, protein C and antithrombin III, remain constant
Hypercoagulability in pregnancy
Hypercoagulability_in_pregnancy
Blood clot (thrombus) that forms within a vein
Pregnancy and the postpartum period Antiphospholipid syndrome (such as lupus anticoagulant) Trauma and minor leg injury Previous VTE Oral contraceptives Hormonal
Venous_thrombosis
Blood test for syphilis
"Beta2-glycoprotein I dependent anticardiolipin antibodies and lupus anticoagulant in patients with recurrent pregnancy loss". Journal of Postgraduate
Venereal Disease Research Laboratory test
Venereal_Disease_Research_Laboratory_test
Test for coagulation of blood
sample) Vitamin K deficiency Antiphospholipid antibody (especially lupus anticoagulant, which paradoxically increases propensity to thrombosis) Coagulation
Partial_thromboplastin_time
Antibody directed against an autogenic protein
more of the individual's own proteins. Many autoimmune diseases (notably lupus erythematosus) are associated with such antibodies. Antibodies are produced
Autoantibody
Spontaneous loss of multiple pregnancies
recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant". The Cochrane Database of Systematic Reviews. 2005 (2) CD002859
Recurrent_miscarriage
Enzyme involved in blood coagulation in humans
antibodies in autoimmune disease may be a factor in the formation of the lupus anticoagulant (also known as antiphospholipid syndrome). Hyperprothrombinemia can
Thrombin
Medical condition
autoantibodies which bind to prothrombin and remove it from the bloodstream (lupus anticoagulant-hypoprothrombinemia syndrome). The most common viral pathogen that
Hypoprothrombinemia
is the major DQ7 allele DQB1*0301 appears to be associated with lupus anticoagulant. DQB1*0304 is the minor DQ7 allele DQ haplotypes of this serotype
HLA-DQ7
Type of autoantibody
Whiting-O'Keefe Q, Corash L, Hellmann D (1987). "Antinuclear antibody, lupus anticoagulant, and anticardiolipin antibody in women with idiopathic habitual abortion
Anti-cardiolipin_antibodies
Human disease
with a normal prothrombin time (PT) includes factor deficiencies, lupus anticoagulant or heparin therapy. The first step to distinguish between factor
Acquired_haemophilia
Medical condition
using lupus anticoagulants often requires more time for the blood to clot. Though this result is often related to bleeding risk, when using lupus anticoagulant
Occlusive_vasculopathy
Topics referred to by the same term
medicinal clay Kaolin clotting time, a sensitive test to detect lupus anticoagulants Kaolin spray, pest control that has kaolin as the main ingredient
Kaolin_(disambiguation)
Lung herniation congenital defect of sternem Lung neoplasm Lupus anticoagulant, familial Lupus erythematosus Lurie–Kletsky syndrome Luteinizing hormone
List_of_diseases_(L)
Medical condition
Neuropsychiatric systemic lupus erythematosus (NPSLE) refers to the neurological and psychiatric manifestations of systemic lupus erythematosus (SLE). SLE
Neuropsychiatric systemic lupus erythematosus
Neuropsychiatric_systemic_lupus_erythematosus
Medical condition
with systemic lupus erythematosus, antiphospholipid syndrome, and malignancies. It is one of the most common cardiac manifestations of lupus (the most common
Libman–Sacks_endocarditis
vitamin K deficiency and lupus anticoagulant. The Ecarin clotting time (ECT) is a test that is widely used for lupus anticoagulant testing in certain regions
Ecarin
Protein-coding gene in humans
"Beta2-glycoprotein I dependent anticardiolipin antibodies and lupus anticoagulant in patients with recurrent pregnancy loss". Journal of Postgraduate
Apolipoprotein_H
German-American biologist and researcher (1954–2023)
FR, Ledford Kraemer MR, Meijer P, Peerschke EI (November 2010). "Lupus anticoagulant testing: performance and practices by north american clinical laboratories"
Ellinor_Peerschke
Class of autoantibodies found in mammals
thrombin that may constitute a fraction of lupus anticoagulant and are seen an increased levels in systemic lupus erythematosus. In mammals, there is normally
Anti-thrombin_antibodies
Topics referred to by the same term
metropolitan area Kaolin clotting time, a medical test used to detect lupus anticoagulant Kensington Corridor Trust, a neighborhood trust in Philadelphia,
KCT
Corticosteroid medication
Methylprednisolone is used to treat several rheumatic diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Methylprednisolone dosage
Methylprednisolone
Norwegian veterinarian and physician (1922–2019)
Stormorken, H; Gjemdal, T; Bjøro, K (1988). "Lupus anticoagulant: a unique case with lupus anticoagulant and habitual abortion together with antifactor
Helge_Stormorken
Species of small, carnivorous mammal native to North America
tribe showed that fishers in California were exposed to and killed by anticoagulant rodenticides associated with marijuana cultivation. In this study, 79%
Fisher_(animal)
Medical condition
taxanes Hydroxyurea dermopathy Exudative hyponychial dermatitis Anticoagulants Anticoagulant-induced skin necrosis Warfarin necrosis Vitamin K Texier's disease
Fixed_drug_reaction
American hematologist (1915–2010)
for vitamin B-12 deficiency. In 1947 he discovered and described lupus anticoagulants. In 1953 he and a research fellow, Ernest W. Smith, described a simple
C._Lockard_Conley
Symptoms resulting from kidney damage
minimal change disease. It may also occur as a complication of diabetes, lupus, or amyloidosis. The underlying mechanism typically involves damage to the
Nephrotic_syndrome
Steroid medication
lichen sclerosus, psoriasis, arthritis, allergies, ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, ocular inflammation
Triamcinolone
Blood vessel disorder causing ulcers in the lower limbs
additional complications. In addition to general supportive measures, anticoagulants and antiplatelet medications can be considered the first-line treatments
Livedoid_vasculopathy
Formation of a blood clot in a deep vein
parenteral anticoagulant to initiate oral anticoagulant therapy. When warfarin is initiated for VTE treatment, a 5-day minimum of a parenteral anticoagulant together
Deep_vein_thrombosis
Swedish Doctor
C4b-Binding Protein: Components Involved in the Regulation of the Protein C Anticoagulant System". Thrombosis and Haemostasis. 66 (1): 049–061. doi:10.1055/s-0038-1646373
Björn_Dahlbäck
Blockage of the hepatic veins that drain the liver
hypercoagulability is not found. Warfarin is the preferred, and best studied anticoagulant, but direct factor Xa inhibitors may also be used. Many patients will
Budd–Chiari_syndrome
Removal, treatment and return of blood plasma
Grifols, S.A. ISBN 978-84-697-1739-4. Wallace, D.J. "Apheresis for lupus erythematosus". Lupus (1999) 8, 174–80. ES application 309216 V. Grifols Lucas: "Aparato
Plasmapheresis
Medication used to treat malaria and babesiosis
only when artemisinins are not available. Quinine is also used to treat lupus and arthritis. Quinine was frequently prescribed as an off-label treatment
Quinine
Abnormally low levels of albumin in the blood
and platelet aggregation in an action similar to the commonly used anticoagulant heparin. It also inhibits inflammatory mediators such as TNF-α and complement
Hypoalbuminemia
Localized discoid lupus erythematosus Localized morphea Lupus erythematosus panniculitis (lupus erythematosus profundus, lupus panniculitis, lupus profundus,
List_of_skin_conditions
Medical condition
smoking, hypertension, migraines, contraceptive use, pregnancy, and systemic lupus erythematosus. Hereditary connective tissue diseases include autosomal polycystic
Cervical_artery_dissection
Type of cells of the immunological system
proteins can get into connective tissue more easily. Heparin is an anticoagulant that inhibits blood clotting and promotes the movement of white blood
White_blood_cell
Presence of a blood clot in the dural venous sinuses or cerebral veins
especially if one is not readily apparent. Treatment is typically with anticoagulants (medications that suppress blood clotting) such as low molecular weight
Cerebral venous sinus thrombosis
Cerebral_venous_sinus_thrombosis
Medical condition
"Radiology-Pathology Conference: pulmonary hyalinizing granuloma associated with lupus-like anticoagulant and Morvan's Syndrome". Clinical Imaging. 31 (4): 264–268. doi:10
Morvan's_syndrome
plasmapheresis, and corticosteroids. Studies have shown that when anticoagulant therapy is withheld, recurrence of thrombosis usually follows. International
Thrombotic_storm
Species of owl
poisoning from pest control efforts is widely reported variously due to anticoagulant rodenticides, strychnine, organophosphates (famphur applied topically
Great_horned_owl
Immunosuppressive medication
Shoenfeld Y (2001). "Azathioprine therapy for patients with systemic lupus erythematosus". Lupus. 10 (3): 152–153. doi:10.1191/096120301676669495. PMID 11315344
Azathioprine
Medical condition where blood clots block small blood vessels
breakdown of clots results in an excess of FDPs, which have powerful anticoagulant properties, contributing to hemorrhage. The excess plasmin also activates
Disseminated intravascular coagulation
Disseminated_intravascular_coagulation
Medical condition
non-immunological (for example, in photodermatitis or as a side effect of anticoagulants). A fixed drug eruption is the term for a drug eruption that occurs
Drug_eruption
Classification based on antibodies and antigens on RBC surfaces
problem caused by a condition such as advanced liver disease, overdose of anticoagulant, or disseminated intravascular coagulation (DIC).[citation needed] Units
Blood_type
Medium-sized North American wild cat
; Bromley, C.; Poppenga, R.H.; Whited, L.; Sauvajot, R.M. (2007). "Anticoagulant exposure and notoedric mange in bobcats and mountain lions in urban
Bobcat
Subgenus of mammals
Csaba; Lanszki, József (2024-10-20). Mateo, Rafael (ed.). "Exposure to anticoagulant rodenticides in steppe polecat (Mustela eversmanii) and European polecat
Putorius
Bleeding from the nose
hypertension) tends to increase the duration of spontaneous epistaxis. Anticoagulant medication and disorders of blood clotting can promote and prolong bleeding
Nosebleed
Presence of blood in urine
natural anticoagulants and promote ongoing bleeding from the urinary tract. Removing all blood clots prevents the formation of this natural anticoagulant. This
Hematuria
Effects of drug consumption during pregnancy
LMWH may not experience the full anticoagulant effect due to the nature of the medication compared to other anticoagulants (i.e. warfarin) and may be less
Drugs_in_pregnancy
Treatment of cancer using drugs that inhibit cell division or kill cells
uncertain. Cyclophosphamide is sometimes used to treat lupus nephritis, a common symptom of systemic lupus erythematosus. Dexamethasone along with either bortezomib
Chemotherapy
valves with the resultant need of drugs in pregnancy in the form of anticoagulants. Diabetes mellitus and pregnancy deals with the interactions of diabetes
Pre-existing disease in pregnancy
Pre-existing_disease_in_pregnancy
Abnormally low levels of platelets in the blood
blockers and proton-pump inhibitors Laboratory error, possibly due to the anticoagulant EDTA in CBC specimen tubes; a citrated platelet count is a useful follow-up
Thrombocytopenia
Category of drugs
term has come to pertain to many other diseases, such as Crohn's disease, lupus erythematosus, Sjögren's disease, immune thrombocytopenic purpura, myasthenia
Disease-modifying antirheumatic drug
Disease-modifying_antirheumatic_drug
colorectal cancer Olendalizumab mab humanized complement C5a systemic lupus erythematosus, lupus nephritis, acute graft-versus-host disease Olokizumab mab humanized
List of therapeutic monoclonal antibodies
List_of_therapeutic_monoclonal_antibodies
Corticosteroid medication
headaches, vasculitis, acute lymphoblastic leukemia, autoimmune hepatitis, lupus, Kawasaki disease, dermatomyositis, post-myocardial infarction syndrome
Prednisolone
Medical condition
drugs, anticoagulants, and lipid-lowering drugs Genetics Autoimmune disorders: alopecia areata, discoid lupus erythematosus, chronic cutaneous lupus erythmatosus
Madarosis
Procedure to retain reproductive ability
Chemotherapy and radiation treatments for cancer and autoimmune conditions like Lupus and Multiple Sclerosis have the ability to affect reproductive health. The
Fertility_preservation
Chemical compound
acute pancreatitis Adverse effects may occur for individuals who: Take anticoagulants ('blood thinners') such as warfarin (Coumadin), diabetes medications
Thiamazole
Substance that stimulates the immune system
adaptive and innate immune responses. Some autoimmune diseases such as lupus erythematosus strike women preferentially, and their onset often coincides
Immunostimulant
Inflammation of a vein due to a blood clot
utilizing pain control (such as NSAIDs), application of heat, and use of anticoagulants. Compression stockings may help prevent these for people with varicose
Thrombophlebitis
Disease of the kidney
(Berger's disease) such as liver failure, cancer, celiac disease, systemic lupus erythematosus, rheumatoid arthritis, heart failure, reactive arthritis,
IgA_nephropathy
Medical condition
be associated with cryofibrinogenemia. These diseases include systemic lupus erythematosus, Sjögren syndrome, rheumatoid arthritis, mixed connective
Cryofibrinogenemia
Class of steroid hormones
Multiple Myeloma Rheumatology/Immunology Rheumatoid arthritis Systemic lupus erythematosus Polymyalgia rheumatica Polymyositis Dermatomyositis Polyarteritis
Corticosteroid
Medical techniques to separate one or more components of blood
in Donation Center settings. To stop the blood from coagulating, an anticoagulant is automatically mixed with the blood as it is pumped from the body
Apheresis
Chemical compound
cholesterol side-chain cleavage Import protein into mitochondrial matrix Anticoagulant function Modulates α-synuclein - malfunction of this process is thought
Cardiolipin
Species of owl
Okoniewski, J. C. & Stedelin, J. R. (1999). "Poisoning of wildlife with anticoagulant rodenticides in New York". Journal of Wildlife Diseases. 35 (2): 187–193
Snowy_owl
Class of therapeutic drug
29 January 2020. "Risk of internal bleeding doubles when people on anticoagulants take NSAID painkiller". www.escardio.org. Archived from the original
Nonsteroidal anti-inflammatory drug
Nonsteroidal_anti-inflammatory_drug
Cocktail of drugs ineffective in treating COVID-19
hydroxychloroquine, ivermectin, azithromycin, bromhexine, nitazoxanide, anticoagulants, and zinc supplements. At the start of the pandemic, specifically in
COVID_kit
Overreaction of the immune system to an antigen
hypersensitivities such as lupus, complement deficiencies (particularly in the classical pathway) are a major risk factor for developing systemic lupus erythematosus
Hypersensitivity
Potentially fatal complication of pregnancy
heparin in these cases could be attributable not only to it being an anticoagulant useful in the treatment of DIC, but also due to its ability to enhance
Amniotic_fluid_embolism
Drug that inhibits activity of immune system
compound. In small doses, it is very efficient in the therapy of systemic lupus erythematosus, autoimmune hemolytic anemias, granulomatosis with polyangiitis
Immunosuppressive_drug
disease. Discoid lupus erythematosus is an uncommon autoimmune disease of the skin in dogs. It does not progress to systemic lupus erythematosus in dogs
List_of_dog_diseases
Medical condition
other vitamins to replenish what minerals the kidneys have leaked out. Anticoagulants (such as aspirin, dipyridamole, and warfarin) are used to prevent clot
Congenital_nephrotic_syndrome
Deadly zoonotic disease
(1972-09-01). "Vampire bat control by systemic treatment of livestock with an anticoagulant". Science. 177 (4051): 806–808. Bibcode:1972Sci...177..806T. doi:10
Rabies_in_animals
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LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
LUPUS ANTICOAGULANT
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