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IRGM

  • IRGM
  • Protein-coding gene in the species Homo sapiens

    family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is encoded by the IRGM gene. IRGM is a member of

    IRGM

    IRGM

    IRGM

  • Crohn's disease
  • Type of inflammatory bowel disease

    autophagy-related 16-like 1, ATG16L1 and the immunity-related GTPase M, IRGM) are involved in innate immune responses against gut microbiota, while one

    Crohn's disease

    Crohn's disease

    Crohn's_disease

  • Sukhoi Su-25
  • Soviet attack aircraft introduced 1978

    protection against infra-red guided missiles (IRGM), a minimal requirement on today's battle fields where IRGMs proliferate. The Su-25UTG (Uchebno-Trenirovochnyy

    Sukhoi Su-25

    Sukhoi Su-25

    Sukhoi_Su-25

  • List of disabled human pseudogenes
  • loss of the gene causes tail shortening loss. Resurrected pseudogenes: IRGM, associated with the immune system Merling RK, Kuhns DB, Sweeney CL, Wu X

    List of disabled human pseudogenes

    List_of_disabled_human_pseudogenes

  • IRGs
  • humans out of which IRGM is known to be an orthologue of mouse Irgm1. There are four isoforms of IRGM (a-d). Unlike mouse IRGs, human IRGM isoforms are always

    IRGs

    IRGs

    IRGs

  • Vojo Deretic
  • American geneticist

    IRGM and TRIMs including TRIM5, TRIM16, PYRIN/TRIM20, and TRIM21, which act as autophagic receptor-regulators. Their studies further showed how IRGM assembles

    Vojo Deretic

    Vojo Deretic

    Vojo_Deretic

  • Endogenous retrovirus
  • Inherited retrovirus encoded in an organism's genome

    reading frame, causing the rebirth of the human immunity related GTPase gene (IRGM). ERV insertions have also been shown to generate alternative splice sites

    Endogenous retrovirus

    Endogenous retrovirus

    Endogenous_retrovirus

  • Interferon-inducible GTPase 5
  • Protein-coding gene in the species Homo sapiens

    Mediated mRNA Decay Factor (SMG9). There is one paralog for IRGC named IRGM. IRGM, or immunity related GTPase M, is associated with intracellular defense

    Interferon-inducible GTPase 5

    Interferon-inducible GTPase 5

    Interferon-inducible_GTPase_5

  • List of human protein-coding genes 4
  • HGNC:5358; Q02556 7784 IRF9 HGNC:6131; Q00978 7785 IRGC HGNC:28835; Q6NXR0 7786 IRGM HGNC:29597; A1A4Y4 7787 IRGQ HGNC:24868; Q8WZA9 7788 IRS1 HGNC:6125; P35568

    List of human protein-coding genes 4

    List_of_human_protein-coding_genes_4

  • ZNF300
  • Human protein-coding gene

    "Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease". Human Molecular Genetics. 19 (9): 1828–1839

    ZNF300

    ZNF300

    ZNF300

  • Mir-196 microRNA precursor family
  • RNA family

    Hofman P (2011). "A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease"

    Mir-196 microRNA precursor family

    Mir-196 microRNA precursor family

    Mir-196_microRNA_precursor_family

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