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HUS1

  • HUS1
  • Protein-coding gene in the species Homo sapiens

    Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene. The protein encoded by this gene is a component of an evolutionarily

    HUS1

    HUS1

    HUS1

  • RAD1 homolog
  • Protein-coding gene in the species Homo sapiens

    germ cells and infertility. RAD1 homolog has been shown to interact with: HUS1, RAD17, and RAD9A, GRCh38: Ensembl release 89: ENSG00000113456 – Ensembl

    RAD1 homolog

    RAD1 homolog

    RAD1_homolog

  • Microsporidia
  • Phylum of fungi

    derive from animals and bacteria, and some even from fungi. The Rad9-Rad1-Hus1 protein complex (also known as the 9-1-1 complex) in eukaryotes is recruited

    Microsporidia

    Microsporidia

    Microsporidia

  • G2-M DNA damage checkpoint
  • Cell cycle checkpoint in eukaryotic organisms

    abolishes checkpoint DNA repair, including rad1, rad9, hus1 and rad17. It has been hypothesized that rad9, hus1 and rad17 are similar to proteins involved in forming

    G2-M DNA damage checkpoint

    G2-M DNA damage checkpoint

    G2-M_DNA_damage_checkpoint

  • RAD9A
  • Protein-coding gene in the species Homo sapiens

    It forms a checkpoint protein complex with Rad1 and Hus1. This is also known as the Rad9-Rad1-Hus1 or 9-1-1 complex. This complex is recruited by checkpoint

    RAD9A

    RAD9A

    RAD9A

  • Ataxia telangiectasia and Rad3 related
  • Protein kinase that detects DNA damage and halts cell division

    that are needed for ATR activation. While RPA recruits ATRIP, the RAD9-RAD1-HUS1 (9-1-1) complex is loaded onto the DNA adjacent to the ssDNA; though ATRIP

    Ataxia telangiectasia and Rad3 related

    Ataxia telangiectasia and Rad3 related

    Ataxia_telangiectasia_and_Rad3_related

  • List of human protein-coding genes 4
  • HGNC:26909; P83105 7369 HTT HGNC:4851; P42858 7370 HUNK HGNC:13326; P57058 7371 HUS1 HGNC:5309; O60921 7372 HUS1B HGNC:16485; Q8NHY5 7373 HUWE1 HGNC:30892; Q7Z6Z7

    List of human protein-coding genes 4

    List_of_human_protein-coding_genes_4

  • CpG site
  • Region of often-methylated DNA with a cytosine followed by a guanine

    RAD51B, XRCC3, RAD54B, BRCA1, SHFM1, GEN1, FANCE, FAAP20, SPRTN, SETMAR, HUS1, and PER1. About seventeen types of cancer are frequently deficient in one

    CpG site

    CpG site

    CpG_site

  • RFC3
  • Protein-coding gene in the species Homo sapiens

    checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9". The Journal of Biological Chemistry. 275 (38): 29767–71. doi:10

    RFC3

    RFC3

    RFC3

  • HDAC1
  • Protein-coding gene in the species Homo sapiens

    Death-associated protein 6, EED, EVI1, EZH2, FKBP3, GATA1, HMG20B, HSPA4, HUS1, Histone deacetylase 2, Homeobox protein TGIF1, Host cell factor C1, IFRD1

    HDAC1

    HDAC1

    HDAC1

  • DNA damage (naturally occurring)
  • Damage in DNA which occurs naturally

    DNA is damaged, it is hypothesized that RAD9 forms a complex with RAD1 and HUS1, and this complex is recruited to sites of DNA damage. It is in this way

    DNA damage (naturally occurring)

    DNA_damage_(naturally_occurring)

  • Proliferating cell nuclear antigen
  • Mammalian protein found in Homo sapiens

    Cohesion 2 Flap structure-specific endonuclease 1 GADD45A GADD45G HDAC1 HUS1 ING1 KCTD13 KIAA0101 Ku70 Ku80 MCL1 MSH3 MSH6 MUTYH P21 POLD2 POLD3 POLDIP2

    Proliferating cell nuclear antigen

    Proliferating cell nuclear antigen

    Proliferating_cell_nuclear_antigen

  • DNA clamp
  • Protein family

    eukaryotes, a homologous, heterotrimeric "9-1-1 clamp" made up of RAD9-RAD1-HUS1 (911) is responsible for DNA damage checkpoint control. This 9-1-1 clamp

    DNA clamp

    DNA clamp

    DNA_clamp

  • List of fictional astronauts (exploration of inner Solar System)
  • last name given) NashaSlava1: Klara Vasily Yuraj (no last names given) JanHus1: Jakub Procházka Spaceman of Bohemia (2017), novel Spaceman (2024), film

    List of fictional astronauts (exploration of inner Solar System)

    List of fictional astronauts (exploration of inner Solar System)

    List_of_fictional_astronauts_(exploration_of_inner_Solar_System)

  • Eukaryotic DNA replication
  • DNA replication in eukaryotic organisms

    proteins are localized to a valid site of DNA replication stress. The RAD9-HUS1-Rad1 (9-1-1) heterotrimeric clamp and its clamp loader RFCRad17 are able

    Eukaryotic DNA replication

    Eukaryotic DNA replication

    Eukaryotic_DNA_replication

  • Regulation of transcription in cancer
  • Aspect of cancer

    RAD51B, XRCC3, RAD54B, BRCA1, SHFM1, GEN1, FANCE, FAAP20, SPRTN, SETMAR, HUS1, and PER1. About seventeen types of cancer are frequently deficient in one

    Regulation of transcription in cancer

    Regulation_of_transcription_in_cancer

  • Werner syndrome helicase
  • Enzyme found in humans

    fragmentation. As shown by Pichierri et al., WRN interacts with the RAD9-RAD1-HUS1 (9.1.1) complex, one of the central factors of the replication checkpoint

    Werner syndrome helicase

    Werner syndrome helicase

    Werner_syndrome_helicase

  • TOPBP1
  • Protein-coding gene in the species Homo sapiens

    TOPBP1 was found to associate with Rad9, which forms a complex with Rad1 and Hus1, hereby termed the 9-1-1 DNA repair clamp. TOPBP1 binds to Rad9 with its

    TOPBP1

    TOPBP1

    TOPBP1

  • CLSPN
  • Protein-coding gene in humans

    Syljuåsen RG, Lukas J, Bartek J (2006). "ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage". Cell Cycle

    CLSPN

    CLSPN

    CLSPN

  • RAD17
  • Protein-coding gene in the species Homo sapiens

    phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be

    RAD17

    RAD17

    RAD17

  • Bcl-2-associated death promoter
  • Mammalian protein found in Homo sapiens

    Lieberman HB, Pledger WJ, Wang HG (November 2000). "PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition". Oncogene. 19

    Bcl-2-associated death promoter

    Bcl-2-associated death promoter

    Bcl-2-associated_death_promoter

  • Bcl-2-like protein 1
  • Protein-coding gene in the species Homo sapiens

    Singh S, Lieberman HB, Pledger WJ, Wang HG (Nov 2000). "PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition". Oncogene. 19

    Bcl-2-like protein 1

    Bcl-2-like protein 1

    Bcl-2-like_protein_1

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Online names & meanings

  • YGERNE
  • Female

    Arthurian

    YGERNE

    , the virgin.

  • Acarya
  • Boy/Male

    Assamese, Hindu, Indian, Kannada, Sanskrit, Telugu

    Acarya

    Teacher; Another Name for Drona

  • Fazeela
  • Girl/Female

    Arabic, Gujarati, Hindu, Indian, Kannada, Marathi, Muslim

    Fazeela

    Faithful

  • Zamaan
  • Boy/Male

    Arabic

    Zamaan

    Time; Age; Destiny

  • Laraine
  • Girl/Female

    American, Australian, British, Christian, English, French, Latin

    Laraine

    Sorrowful; From Lothair's Kingdom; Sea Bird; The Bay; Laurel; Plant; Land of the People of Lothar

  • Madeley
  • Surname or Lastname

    English

    Madeley

    English : habitational name from places so named in Shropshire and Staffordshire, named in Old English with the personal name Māda + lēah ‘woodland clearing’.

  • Tone
  • Girl/Female

    Australian, Danish, Swedish

    Tone

    Priceless

  • EUFROZINA
  • Female

    Hungarian

    EUFROZINA

    Hungarian form of Greek Euphrosyne, EUFROZINA means "joy, mirth."

  • Narine
  • Girl/Female

    Hindu

    Narine

  • Vartanu | வர்தாணு
  • Boy/Male

    Tamil

    Vartanu | வர்தாணு

    Beautiful

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