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Chemical compound
Glycinamide is an organic compound with the molecular formula H2NCH2C(O)NH2. It is the amide derivative of the amino acid glycine. It is a water-soluble
Glycinamide
Any salt of an organic base and hydrochloric acid
"Asymmetric Synthesis of α-Amino Acids by the Alkylation of Pseudoephedrine Glycinamide: L-Allylglycine and N-BOC-l-Allylglycine". Organic Syntheses. 76: 57
Hydrochloride
Protein domain
Phosphoribosylamine—glycine ligase, also known as glycinamide ribonucleotide synthetase (GARS), (EC 6.3.4.13) is an enzyme that catalyzes the chemical
Phosphoribosylamine—glycine ligase
Phosphoribosylamine—glycine_ligase
Class of enzymes
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2), also known as glycinamide ribonucleotide transformylase (GAR Tfase), is an enzyme with systematic
Phosphoribosylglycinamide formyltransferase
Phosphoribosylglycinamide_formyltransferase
catalyzes the chemical reaction ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate
Phosphoribosylformylglycinamidine synthase
Phosphoribosylformylglycinamidine_synthase
Chemical compound
PMID 5283931. Petersson M, Uvnäs-Moberg K (December 2004). "Prolyl-leucyl-glycinamide shares some effects with oxytocin but decreases oxytocin levels". Physiology
Melanocyte-inhibiting_factor
Mammalian protein found in Homo sapiens
apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase". Biochemistry. 44 (29): 9841–50. doi:10
Trifunctional purine biosynthetic protein adenosine-3
Trifunctional_purine_biosynthetic_protein_adenosine-3
Antihypotensive medication
with azide and the resulting product 6 reduced catalytically to the glycinamide, midodrine (7). Midodrine was discovered by 1971. It was approved in
Midodrine
Chemical compound
Glycinamide ribonucleotide (or GAR) is a biochemical intermediate in the formation of purine nucleotides via inosine-5-monophosphate, and hence is a building
Glycineamide_ribonucleotide
Chemical compound
synthesis—thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). By inhibiting the formation
Pemetrexed
Peptide consisting of three amino acids joined by peptide bonds
that also acts as an inhibitor of calpain Melanostatin (prolyl-leucyl-glycinamide) is a peptide hormone produced in the hypothalamus that inhibits the
Tripeptide
Chemical compound
"Asymmetric Synthesis of α-Amino Acids by the Alkylation of Pseudoephedrine Glycinamide: L-Allylglycine and N-BOC-l-Allylglycine". Organic Syntheses. 76: 57
Glycine methyl ester hydrochloride
Glycine_methyl_ester_hydrochloride
Treatment of cancer using drugs that inhibit cell division or kill cells
DHFR, aminoimidazole carboxamide ribonucleotide formyltransferase and glycinamide ribonucleotide formyltransferase. The fluoropyrimidines include fluorouracil
Chemotherapy
Chemical compound
Trimecaine Names IUPAC name N2,N2-Diethyl-N1-(2,4,6-trimethylphenyl)glycinamide Systematic IUPAC name 2-(Diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
Trimecaine
Protein structural motif
TJ, Stubbe J, Ealick SE (November 1998). "X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli". Biochemistry. 37 (45):
ATP-grasp
Chemical reactions and pathways involving lysis of purine nucleotides
Caperelli CA, Hua M, Vince R (April 1996). "Substrate specificity of glycinamide ribonucleotide synthetase from chicken liver". The Journal of Biological
Purine_metabolism
Molecule that blocks enzyme activity
purine biosynthesis, a potent Multi-substrate Adduct Inhibitor (MAI) to glycinamide ribonucleotide (GAR) TFase was prepared synthetically by linking analogues
Enzyme_inhibitor
Glufosfamide – Glutamine – Glutathione – Glutathione S-transferase – Glycinamide ribonucleotide formyltransferase inhibitor – Glycolysis – Glycopeptide
Index_of_oncology_articles
Chemical reaction
biosynthesis of purines. These reactions are catalyzed by the enzymes glycinamide ribonucleotide (GAR) transformylase and 5-aminoimidazole-4-carboxyamide
Formylation
Chemical compound
Butanilicaine Names IUPAC name N2-Butyl-N1-(2-chloro-6-methylphenyl)glycinamide Systematic IUPAC name 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide
Butanilicaine
Drugs used to achieve relief from pain
cataract surgery. As per bromfenac. Niflumic acid Comes in free acid form, glycinamide and ethyl ester form; practically insoluble in water, soluble in ethanol
Analgesic
Pharmaceutical compound
also known as 621 I.S. or as N,N-diethyl-N′-(1,2,3,4-tetrahydronaphthyl)glycinamide, is an oxytocic drug related to ergometrine which does not appear to
Tochergamine
Chemical compound
name N2-(2,5-Dichlorobenzoyl)-N-[(1R)-1-(dihydroxyboryl)-3-methylbutyl]glycinamide CAS Number 1072833-77-2 PubChem CID 25183872 DrugBank DB09570 ChemSpider
Ixazomib
Buffering agents for biochemical and biological research
HEPPSO [fr] 7.90 1980 HEPPS 8.10 7.6–8.6 1972 Tricine 8.15 7.4–8.8 1966 Glycinamide 8.20 1966 Glycylglycine 8.20 7.5–8.9 1966 Bicine 8.35 7.6–9.0 1966 TAPS
Good's_buffers
Process where substrates are converted into more complex products in living organisms
Ebihara, A; Nakagawa, N; Kawai, G (October 2010). "Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria". Journal
Biosynthesis
Nucleotide containing ribose as its pentose component
glycine and ATP, activates the glycine carboxylase group of 5-PRA to form Glycinamide ribonucleotide (GAR). Co-enzyme N10-formyl-THF, along with enzyme GAR
Ribonucleotide
formamide and methylformamide are rare. Diacetamide (HN(C(O)CH3)2) and glycinamide (H2NC(O)CH2NH2) are two of many examples of chelating amide ligands.
Transition metal carboxamide complex
Transition_metal_carboxamide_complex
Cleavage of C-terminal glycinamide from polypeptides This enzyme inactivates vasopressin and oxytocin by splitting off glycinamide. Fruhaufová, L.; Suska-Brezezinska
Peptidyl-glycinamidase
Index of chemical compounds with the same molecular formula
74.08 g/mol, exact mass: 74.0480 u) may refer to: Azoxymethane (AOM) Glycinamide N-Nitrosodimethylamine (NDMA), or DMN This set index page lists chemical
C2H6N2O
Self-stable region of a protein's chain that folds independently from the rest
AIR synthetase and GAR transformylase domains (GARs-AIRs-GARt; GAR: glycinamide ribonucleotide synthetase/transferase; AIR: aminoimidazole ribonucleotide
Protein_domain
larvae, are co-treated with naloxone. Both naloxone and prolyl-leucyl-glycinamide (another opiate antagonist in mammals) reduced the analgesic effects
Pain_in_fish
Intramolecular route to Co glycinamide complex.
Transition metal amino acid complexes
Transition_metal_amino_acid_complexes
Pharmaceutical compound
2-(3-(2-aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide Routes of administration Intranasal, subcutaneous Drug class Serotonin
IS-159
Chemical compound
latter. Synthesis starts by reductive amination of salicylaldehyde and glycinamide to give 3. The synthesis is completed by reaction with phosgene and NaHCO3
Caroxazone
Highly ordered, branched polymeric molecule
Johnson KD, Khan AA, O'Hagan SE, et al. (August 2016). "Poly Ethoxy Ethyl Glycinamide (PEE-G) Dendrimers: Dendrimers Specifically Designed for Pharmaceutical
Dendrimer
Chemical compound
activity of the N-methyl-D-aspartate receptor antagonist N-(2-Indanyl)-glycinamide hydrochloride (CHF3381) in experimental models of inflammatory and neuropathic
Indantadol
Chemical compound
N-Ethyl-N2-(6-methoxy-3-pyridinyl)-N2-[(2-methylphenyl)sulfonyl]-N-(3-pyridinylmethyl)glycinamide CAS Number 680590-49-2 Y PubChem CID 9981404 ChemSpider 8156996 UNII
EMPA_(drug)
(rare). Pemetrexed IV Dihydrofolate reductase, thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. Malignant mesothelioma and
List_of_antineoplastic_agents
Polymer showing drastic changes in physical properties with temperature
(January 10, 2012). "Upper Critical Solution Temperature of Poly(N-acryloyl glycinamide) in Water: A Concealed Property". Macromolecules. 45 (1): 374–384. Bibcode:2012MaMol
Temperature-responsive polymer
Temperature-responsive_polymer
Chemical compound
mouth ATC code none Identifiers IUPAC name N-(1-methyl-1,2-diphenylethyl)glycinamide CAS Number 128298-28-2 Y PubChem CID 60511 ChemSpider 54551 N UNII EH6763C1IC
Remacemide
Mammalian protein found in Homo sapiens
McKellar BR, Caperelli CA, Hua M, Vince R (1996). "Substrate specificity of glycinamide ribonucleotide synthetase from chicken liver". The Journal of Biological
Amidophosphoribosyltransferase
Amidophosphoribosyltransferase
Medical intervention
Pemetrexed inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase. Pemetrexed induces cell cycle arrest
Treatment_of_lung_cancer
Patterson, D. (1986). "Assignment of a third purine biosynthetic gene (glycinamide ribonucleotide transformylase) to human chromosome 21". American Journal
Purinosome
Chemical compound
phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1→6)-disulfide Other names H-Cys(1)-Phe-Phe-Gln-Asn-Cys(1)-Pro-Arg-Gly-NH2
Phenypressin
Pharmaceutical compound
eta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds". Journal of Medicinal Chemistry. 48 (24): 7808–7820
GP3269
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