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Regulator for flow of signals in neural networks
In neural networks, the gating mechanism is an architectural motif for controlling the flow of activation and gradient signals. They are most prominently
Gating_mechanism
Memory unit used in neural networks
In artificial neural networks, the gated recurrent unit (GRU) is a gating mechanism used in recurrent neural networks, introduced in 2014 by Kyunghyun
Gated_recurrent_unit
Type of membrane proteins
exclusively use this mechanism of gating are the TREK-1 and TRAAK channels. In studies using mammalian hair cells, the mechanism that pulls on proteins
Mechanosensitive_channels
Automatic process by which the brain adjusts to stimuli
referred to as gating or filtering, sensory gating prevents an overload of information in the higher-order centers of the brain. Sensory gating can also occur
Sensory_gating
these gating processes occurs in response to these triggers are known as the kinetics of gating. Some drugs and many ion channel toxins act as 'gating modifiers'
Gating_(electrophysiology)
Topics referred to by the same term
Gating (cytometry), manually selecting a population during flow cytometry analysis Gating mechanism, an architectural motif in neural networks. Gate (disambiguation)
Gating
Protein subfamily of calcium-activated potassium channels
conductance) due to its higher conductance 20 – 80 pS. The SK channel gating mechanism is controlled by intracellular calcium levels. Calcium enters the cell
SK_channel
Power management technique for synchronous digital circuits
(typically as module-level clock gating) by instantiating library-specific integrated clock gating (ICG) cells to gate the clocks of specific modules or
Clock_gating
Class of iron-containing proteins
reversible Fe3+/Fe2+ redox coupling by the reduction of Fe3+ to Fe2+ and a gating mechanism caused by the conformational changes of Leu41. Upon the reduction of
Rubredoxin
Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition
Synaptic_gating
Power-saving technique for circuits
leakage power, power gating has the benefit of enabling Iddq testing. Power gating affects design architecture more than clock gating. It increases time
Power_gating
An electric gate is a type of gate that can be opened and closed using an electrically powered mechanism. Driveway gate openers can be the rollback (sliding)
Electric_gate
Type of ion channel transmembrane protein
diverse class of voltage-gated channels, with over 100 encoding human genes. These types of channels differ significantly in their gating properties; some inactivating
Voltage-gated_ion_channel
Water channel protein in cell membranes
cellular water due to drought. The gating of an aquaporin is carried out by an interaction between a gating mechanism and the aquaporin, which causes a
Aquaporin
Circuit components acting like computer memory
addressable register involves gating its output data onto a shared bus. Depending on the application, the gating mechanism may employ multiplexers or tri-state
Hardware_register
Family of transport proteins
in the muscles and is expressed in the electric organ. Gating (electrophysiology) Ligand-gated ion channel List of investigational analgesics Sodium channel
Voltage-gated_sodium_channel
Mathematical activation function in data analysis
vanishing gradient problem during backpropagation. Activation function Gating mechanism Ramachandran, Prajit; Zoph, Barret; Le, Quoc V. (2017-10-27). "Searching
Swish_function
Class of transport proteins
alters the selectivity. Gating occurs through two mechanisms: protopore or fast gating and common or slow gating. Common gating involves both protein subunits
Chloride_channel
Pore-forming membrane protein
membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions
Ion_channel
Type of artificial neural network
previous neural networks. It uses skip connections modulated by learned gating mechanisms to regulate information flow, inspired by long short-term memory (LSTM)
Highway_network
Group of transport proteins
proposed in explaining the gating mechanism of MS channels: membrane-mediated mechanism and trapdoor mechanism. The trapdoor mechanism is responsible for the
Large-conductance mechanosensitive channel
Large-conductance_mechanosensitive_channel
2017 research paper by Google
technical report and formally published in 1997), an RNN that introduced gating mechanisms to mitigate the vanishing gradient problem, allowing efficient learning
Attention_Is_All_You_Need
Transmembrane protein allowing sodium ions in and out
channels are treated as a population that are affected by three independent gating variables. Each of these variables can attain a value between 1 (fully permeant
Sodium_channel
Bolt-action repeating rifle
War. Although "Krags" were popular and efficient, the side loading gate mechanism was slow and cumbersome to reload in combat compared to the clip loaded
Springfield_Model_1892–99
Ion channel complex through which calcium ions pass
following tables explain gating, gene, location and function of different types of calcium channels, both voltage and ligand-gated. voltage-operated calcium
Calcium_channel
Level crossing protective system with four barriers
A four-quadrant gate or full-barrier equipment is a type of boom barrier gate protecting a grade crossing. It has a gate mechanism on both sides of the
Four-quadrant_gate
Class of porin ion channels in the outer mitochondrial membrane
Radhakrishnan (February 2026). "Protein–lipid interplay governs ion channel gating and bioenergetics in human mitochondrial VDAC3". Protein Science. 35 (2)
Voltage-dependent anion channel
Voltage-dependent_anion_channel
Protein-coding gene in the species Homo sapiens
Biology Has Directly Impacted Our Understanding of P2X Receptor Function and Gating". In Nicke A (ed.). The P2X7 Receptor. Methods in Molecular Biology. Vol
P2RX4
Class of transport proteins
contribute to the gating charge. The position of these arginines, known as gating arginines, are highly conserved in all voltage-gated potassium, sodium
Voltage-gated potassium channel
Voltage-gated_potassium_channel
Group of voltage-gated ion channels permeable to Ca2+
several functions including modulation of gating. There are several different kinds of high-voltage-gated calcium channels (HVGCCs). They are structurally
Voltage-gated_calcium_channel
Family of transport proteins
the voltage sensing domain, the conduction pore, and gating apparatus. Like most voltage-gated ion channels, the α-subunit is composed of 4 subunits
L-type_calcium_channel
in turn provides a dynamic gating mechanism for controlling working memory updating. Computationally, the learning mechanism is designed to simultaneously
Prefrontal cortex basal ganglia working memory
Prefrontal_cortex_basal_ganglia_working_memory
Abnormally fast heart rhythm
excessively high rates arising from the supraventricular areas by a "gating mechanism" at the atrioventricular node, which allows only a proportion of the
Supraventricular_tachycardia
Electric current in the heart
responsible for starting the diastolic depolarization phase (DD); by this mechanism, the funny current controls the rate of spontaneous activity of sinoatrial
Pacemaker_current
Family of transport proteins
Light-gated ion channels are a family of ion channels regulated by electromagnetic radiation. Other gating mechanisms for ion channels include voltage-gated
Light-gated_ion_channel
Ion channel that selectively passes K+
prokaryotic and eukaryotic channels, pH gating domain of KcsA, cyclic nucleotide gating domains, and voltage gated potassium channels. N-type inactivation
Potassium_channel
Type of ion channel transmembrane protein
(2004). "Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels"
Ligand-gated_ion_channel
Mammalian protein found in humans
changing conformations between conducting and non-conducting states (called 'gating'). Between the S5 and S6 helices, there is an extracellular loop (known
KCNH2
Shackle with a spring-loaded gate
carabiners, but have an additional mechanism securing the gate to prevent unintentional opening during use. These mechanisms may be either threaded sleeves
Carabiner
Enzyme
ubiquinone, is shown in image 4. It has also been proposed that a gating mechanism may be in place to prevent the electrons from tunneling directly to
Succinate_dehydrogenase
Intermembrane proteins
slowly gating and strongly sensitive to cAMP. HCN2 and HCN3 have intermediate properties. Hyperpolarization-activated and cyclic nucleotide–gated (HCN)
HCN_channel
Class of transport proteins
2006). "Crystal structures of a ligand-free MthK gating ring: insights into the ligand gating mechanism of K+ channels". Cell. 126 (6): 1161–73. doi:10
Calcium-activated potassium channel
Calcium-activated_potassium_channel
French neuroscientist (born 1936)
receptor gating mechanism. Biophys. J. 88:3954-3965 Calimet N., Simoes M., Changeux J.-P., Karplus M., Taly A., Cecchini M. (2013) From the Cover: A gating mechanism
Jean-Pierre_Changeux
Prokaryotic potassium ion channel
pH gating in KcsA channel function. In 2006, the Perozo group proposed a mechanistic explanation for the effects of voltage fields on KcsA gating. After
KcsA_potassium_channel
State of unresponsiveness to repeated stimuli
property of voltage-gated sodium channels and the lag of potassium channels in closing. Voltage-gated sodium channels have two gating mechanisms, the activation
Refractory period (physiology)
Refractory_period_(physiology)
Class of intracellular transport proteins
EF-hands originating from the α-solenoid scaffold, suggesting a mechanism for channel gating by Ca2+. Each major ryanodine receptor isoform (RyR1, RyR2, and
Ryanodine_receptor
Y, Derebe MG, Jiang Y (2012). "Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel". eLife. 1 e00184. doi:10.7554/eLife
Potassium_in_biology
Class of transport proteins
V (July 2015). "Comparative sequence analysis suggests a conserved gating mechanism for TRP channels". The Journal of General Physiology. 146 (1): 37–50
Transient receptor potential channel
Transient_receptor_potential_channel
Cell-cell junction composed of innexins or connexins
ISBN 0-8153-4072-9. Hu X, Dahl G (1999). "Exchange of conductance and gating properties between gap junction hemichannels". FEBS Lett. 451 (2): 113–117
Gap_junction
Conditions to be met in order to let a signal flow
signal. The gating signal acts as a control mechanism, determining when the main signal can pass through the gate and when it is blocked. The gating signal
Gating_signal
Class of ligand activated receptors localized in surface of plama cell membrane
ISBN 978-0-87893-321-1. Miyazawa A.; Fujiyoshi Y.; Unwin N. (2003). "Structure and gating mechanism of the acetylcholine receptor pore". Nature. 423 (6943): 949–955. Bibcode:2003Natur
Cell_surface_receptor
Integral membrane protein
S2CID 36451231. Miyazawa A, Fujiyoshi Y, Unwin N (2003). "Structure and gating mechanism of the acetylcholine receptor pore". Nature. 423 (6943): 949–55. Bibcode:2003Natur
Acetylcholine_receptor
Family of ion channel proteins
2006). "Crystal structures of a ligand-free MthK gating ring: insights into the ligand gating mechanism of K+ channels". Cell. 126 (6): 1161–73. doi:10
Cation_channel_superfamily
Brand of 3D time-of-flight camera products in the 2000s by 3DV Systems
fast gating mechanism. Based on the known speed of light, ZCam coordinates the timing of NIR pulse wave emissions from the illuminator with the gating of
ZCam
Gene found in fruit flies
(February 1998). "Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels". The Journal of General Physiology
Shaker_(gene)
Biological membrane structure
voltage-gated Na+ channel, which allows conduction of an action potential along neurons. All ion pumps have some sort of trigger or "gating" mechanism. In
Lipid_bilayer
Protein-coding gene in the species Homo sapiens
The Kir2.1 inward-rectifier potassium channel is a lipid-gated ion channel encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil
Kir2.1
Type of drug which modulates ion channels
blockers and channel openers. Ion channels are typically categorised by gating mechanism and by the ion they conduct. Note that an ion channel may overlap between
Channel_modulator
Family of transport proteins
identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating". Nat. Genet. 36 (4): 382–7. doi:10.1038/ng1329. PMC 1995438. PMID 15034580
ATP-sensitive potassium channel
ATP-sensitive_potassium_channel
Protein and coding gene in humans
bind TRPA1 non-covalently in the same region as electrophiles and act as a gating modifier toxin for the receptor, stabilizing the channel in an open conformation
TRPA1
Widely distributed inhibitory receptor in the central nervous system
PMID 4329648. Miyazawa A, Fujiyoshi Y, Unwin N (June 2003). "Structure and gating mechanism of the acetylcholine receptor pore". Nature. 423 (6943): 949–55. Bibcode:2003Natur
Glycine_receptor
Mechanism in Intel's x86 architecture for changing the privilege level
A call gate is a mechanism in Intel's x86 architecture for changing the privilege level of a process when it executes a predefined function call using
Call_gate_(Intel)
Group of transport proteins
In Benz R (ed.). Bacterial and eukaryotic porins: structure, function, mechanism. Weinheim: Wiley-VCH. pp. 26–29. ISBN 978-3-527-30775-3. Besnard M, Martinac
Porin_(protein)
Legal term for the physical and emotional stress caused from an injury
medical malpractice or wrongful death cases) Procedural thresholds or gating mechanisms (minimum severity, impairment or percentage thresholds) Reduction
Pain_and_suffering
Type of barrier
mechanism. The gate does not swing on a conventional hinge. Instead, it is fastened to cylinders that loosely encircle a tall post. The bump gate's self-closing
Bump_gate
include voltage gating and chemical modulation. Voltage-gating is a relatively fast modulation categorized into Vj gating and slow voltage gating, which are
Gap_junction_modulation
Protein
striatal synaptic plasticity, possibly by serving as a dopamine-dependent gating mechanism for calcium/CaMKII signaling. It has been predicted that DARPP-32,
PPP1R1B
Class of transport proteins
ML, Wang Z, Baker MR, Sinyagovskiy PA, Chiu W, et al. (November 2015). "Gating machinery of InsP3R channels revealed by electron cryomicroscopy". Nature
Inositol trisphosphate receptor
Inositol_trisphosphate_receptor
Human protein for regulating body temperature
detection of noxious environmental stimuli. TRPV1 is an element of or mechanism used by the mammalian somatosensory system. It is a nonselective cation
TRPV1
Potassium channel
"Structural changes in the cytoplasmic pore of the Kir1.1 channel during pHi-gating probed by FRET". Journal of Biomedical Science. 16 (1): 29. doi:10.1186/1423-0127-16-29
ROMK
Mammalian protein found in humans
inward-facing conformation to an outward-facing one results in channel gating. In particular, NBD dimerization (favored by ATP binding) is coupled to
Cystic fibrosis transmembrane conductance regulator
Cystic_fibrosis_transmembrane_conductance_regulator
Analytical technique used to separate and identify ionized molecules in the gas phase
intervals, a sample of the ions is let into the drift region; the gating mechanism is based on a charged electrode working in a similar way as the control
Ion_mobility_spectrometry
Antihypertensive drug of the calcium channel blocker class
binding pocket and its binding interferes with the voltage sensor and gating mechanism of the channel. Thought to have a domain-interface model of binding
Nitrendipine
Semiconductor memory technology
a storage mechanism in electrically erasable programmable read-only memory (EEPROM), and was an alternative to the standard floating-gate MOSFET technology
Charge_trap_flash
of nociceptive afferent fibres. Melzack and Wall suggested that a gating mechanism is present in the dorsal horn of the spinal cord. They suggested that
Tactile_induced_analgesia
Branch of neuroscience
registering the potentially interesting areas of the retinal input, and a gating mechanism for reducing the amount of incoming visual information, so that the
Computational_neuroscience
Family of transport proteins
(β1-4), each of which have different expression patterns that modify the gating properties of the BK channel. The β1 subunit is primarily responsible for
BK_channel
Membrane protein involved in transportation
transporters, such as rhodopsin The group translocators provide a special mechanism for the phosphorylation of sugars as they are transported into bacteria
Membrane_transport_protein
Peptide neurotoxin
properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating". Biochimica et
Protoxin-I
Protein family
"Alternative splicing in the C-terminus of CaV2.2 controls expression and gating of N-type calcium channels". The Journal of Physiology. 576 (Pt 1): 119–34
N-type_calcium_channel
Voltage-gated potassium channel protein
of the BK channel gating ring 3MT5 – Crystal structure of the human BK gating apparatus 3NAF – Structure of the intracellular gating ring from the human
Calcium-activated potassium channel subunit alpha-1
Calcium-activated_potassium_channel_subunit_alpha-1
Protein-coding gene in the species Homo sapiens
excitability in DRG sensory neurons and hence contribute to pain, but the mechanism by which they do so is not understood. GRCh38: Ensembl release 89: ENSG00000185313
Nav1.8
Protein-coding gene in the species Homo sapiens
N-terminal is unnecessary for proper voltage gating and therefore suggest the flexible beta barrel as the mechanism of conformational change. Atomic Force Microscopy
VDAC1
Class of enzymes
the DNA-binding core had the C-gate closed, this structure captured the gate open, a key step in the two-gate mechanism (see below). More recently, several
Type_II_topoisomerase
2009 film by Roland Emmerich
onto Ark 4. As the gate closes, Tenzin is injured and Gordon is fatally crushed. Tenzin's impact driver lodges in the gate mechanism, preventing it from
2012_(film)
Point of entry to a space enclosed by walls
The Iron Gates of Osgoode Hall, Toronto Beachside gate with a self-latching device and a higher than 54” release mechanism. Military style gates in Chatham
Gate
Family of transport proteins
including TRPN, in the sixth transmembrane domain are critical to the gating mechanism as well. As a mechanoreceptor, TRPN responds to impinging mechanical
TRPN
Protein-coding gene in humans
result, the C-terminal tail is central to functions such as regulating pH gating and channel assembly. Notably, the DNA region of the GJA1 gene encoding
GJA1
Protein-coding gene in humans
1:1:1 ratio. The S3-S4 linkers of Cav1.2 determine the gating phenotype and modulated gating kinetics of the channel. Cav1.2 is widely expressed in the
CACNA1C
Protein-coding gene in humans
in increased sensitization to the menthol stimulus. To investigate the mechanisms of this sensitization, Wasner et al., 2004, performed A fiber conduction
TRPM8
Protein-coding gene in humans
"Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+". The Journal of Biological Chemistry. 275 (37):
ASIC5
Family of toxins produced by spiders
"Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins". J. Mol. Biol.
Spider_toxin
Ionotropic serotonin receptor
helices (M1-M4), with the extracellular M2-M3 loop involved in the gating mechanism; a large cytoplasmic domain between M3 and M4 involved in receptor
5-HT3_receptor
Genetic phenomenon
a role in DNA binding and mRNA transport, making gene gating possible. In addition, gene gating is orchestrated by two protein complexes, Spt-Ada-Gcn5-acetyltransferase
Gene_gating
of the yeast NPC, mapping its architecture and suggesting a virtual gating mechanism for nucleocytoplasmic transport. Additionally, he worked on a method
Michael_Rout
Protein-coding gene in the species Homo sapiens
PMID 15557452. Trudeau MC, Zagotta WN (2002). "Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels". Proc. Natl. Acad. Sci. U.S
CNGB1
Protein-coding gene in the species Homo sapiens
TRPV TRPV5 calcium channels calcium absorption transcellular pathway gating mechanism calmodulin maternal-fetal transport transient neonatal hyperparathyroidism
TRPV6
Protein-coding gene in the species Homo sapiens
Delmas P, Coste B (February 2003). "Na+ channel Nav1.9: in search of a gating mechanism". Trends in Neurosciences. 26 (2): 55–7. doi:10.1016/S0166-2236(02)00030-9
Nav1.9
Group of transmembrane proteins that passively transport potassium ions
While the principal idea of polyamine block is understood, the specific mechanisms are still controversial. All Kir channels require phosphatidylinositol
Inward-rectifier potassium channel
Inward-rectifier_potassium_channel
Computational strategy for large datasets
sub-tasks, each handled by a specialized expert. In the filtering stage, a gating mechanism—acting as a filter that determines the most suitable expert for each
Filter_and_refine
travel, tourism, insurance
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
GATING MECHANISM
travel, tourism, insurance