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Electric current in the heart
The pacemaker current (If, or IKf, also called funny current) is an electric current in the heart that flows through the HCN channel or pacemaker channel
Pacemaker_current
Electrical potential difference in the heart
cells of the heart (e.g., the sinoatrial node), the pacemaker potential (also called the pacemaker current) is the slow, positive increase in voltage across
Pacemaker_potential
Medical device for artificially stimulating heart contractions
A pacemaker, also known as an artificial cardiac pacemaker, is an implanted medical device that generates electrical pulses delivered by electrodes to
Pacemaker
Network of cells that facilitate rhythmic heart contraction
The natural pacemaker is the heart's natural rhythm generator. It employs pacemaker cells that produce electrical impulses, known as cardiac action potentials
Natural_pacemaker
Heart medication
the brand name Procoralan among others, is a medication, which is a pacemaker current (If) inhibitor, used for the symptomatic management of heart-related
Ivabradine
Group of cells in the wall of the heart
in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately 15 mm long, 3 mm wide, and 1 mm
Sinoatrial_node
Intermembrane proteins
The current through HCN channels, designated If or Ih, plays a key role in the control of cardiac and neuronal rhythmicity and is called the pacemaker current
HCN_channel
American neuroscientist and professor emeritus
in the early characterization of the hyperpolarization-activated pacemaker current (f) responsible for the spontaneous rhythmic activity of the sinoatrial
Jeffry_Lansman
Specialized cells used to improve heart regulation
A biological pacemaker is one or more types of cellular components that, when "implanted or injected into certain regions of the heart," produce specific
Biological_pacemaker
Anticholinergic medication used as antidote for nerve agent poisoning
potassium and calcium currents, as well as the slow-inward sodium current that is thought to be responsible for the pacemaker current (If). By hyperpolarizing
Atropine
English band
Gerry and the Pacemakers were an English beat group prominent in the 1960s Merseybeat scene. In common with the Beatles, they came from Liverpool, were
Gerry_and_the_Pacemakers
Interstitial cells found in the gastrointestinal tract
(1 July 1998). "Interstitial cells of Cajal generate a rhythmic pacemaker current". Nature Medicine. 4 (7): 848–851. doi:10.1038/nm0798-848. ISSN 1078-8956
Interstitial_cell_of_Cajal
Part of the enteric nervous system
D. (1998-07-01). "Interstitial cells of Cajal generate a rhythmic pacemaker current". Nature Medicine. 4 (7): 848–851. doi:10.1038/nm0798-848. ISSN 1078-8956
Myenteric_plexus
Biological process in the heart
known as pacemaker cells, that have automatic action potential generation capability. In healthy hearts, these cells form the cardiac pacemaker and are
Cardiac_action_potential
Italian physiologist (born 1948)
and collaborators discovered the so-called "funny" (or "pacemaker") current in cardiac pacemaker cells, a new mechanism involved in the generation of cardiac
Dario_DiFrancesco
Effects that change the heart rate
chronotropic effect. Beta blockers such as metoprolol Acetylcholine Digoxin Pacemaker current (i.e. HCN channel) inhibitors (e.g. ivabradine) Alboni, P.; Menozzi
Chronotropic
Variation in the time intervals between heartbeats
"pacemaker" current. The "Ik decay" hypothesis proposes that pacemaker depolarization results from slow deactivation of the delayed rectifier current,
Heart_rate_variability
Pocket-sized DJ system
The Pacemaker is a pocket-size DJ system invented by Jonas Norberg. The device features include a 120 GB hard drive, a signal-to-noise ratio of 103, and
The_Pacemaker
Topics referred to by the same term
organization Isiah Kiner-Falefa (born 1995), American baseball player Pacemaker current of the heart, IKf This disambiguation page lists articles associated
IKF
increasing the slope of the pacemaker phase, while parasympathetic activation exerts the opposite action. The amount of net inward current required to move the
Diastolic_depolarization
Group of medical conditions characterized by irregular heartbeat
Treatments may include medications, medical procedures such as inserting a pacemaker, and surgery. Medications for a fast heart rate may include beta blockers
Arrhythmia
Devices generating electricity from radioisotope decay
equipment that must operate unattended for long periods, such as spacecraft, pacemakers, medical devices, underwater systems, and automated scientific stations
Atomic_battery
American engineer and inventor (1919–2011)
limited its current load to under 0.1 mA and was thus considered useless. Greatbatch sought to introduce this invention into the pacemaker industry, which
Wilson_Greatbatch
American engineer, inventor, and holistic healthcare promoter (1924–2018)
first external, battery-operated, transistorized, wearable artificial pacemaker in 1957. Bakken was born on January 10, 1924, in Columbia Heights, Minnesota
Earl_Bakken
activity (ECA) is the spontaneous depolarization and repolarization of pacemaker cells known as interstitial cells of Cajal (ICCs) in the smooth muscle
Basal_electrical_rhythm
Enlargement of the heart muscle
use of a pacemaker has been advocated in a subset of individuals, to cause asynchronous contraction of the left ventricle. Since the pacemaker activates
Hypertrophic_cardiomyopathy
English broadcaster and natural historian (born 1926)
independent schools like the Emmanuel Schools Foundation. Attenborough had a pacemaker fitted in June 2013, as well as a double knee replacement in 2015. In
David_Attenborough
Medical condition
the potassium channel that carries the rapid inward rectifier current IKr. This current contributes to the terminal repolarisation phase of the cardiac
Long_QT_syndrome
Disease involving heart or blood vessels
a person could have surgery to replace the valve. For arrhythmias, a pacemaker can be put in place to help reduce abnormal heart rhythms and for a heart
Cardiovascular_disease
Organ found in humans and other animals
with a rhythm determined by a group of pacemaker cells in the sinoatrial node. These generate an electric current that causes the heart to contract, traveling
Heart
Pacemaker crosstalk results when the pacemaker-generated electrical event in one heart chamber is sensed by the lead in another chamber, resulting in inappropriate
Pacemaker_crosstalk
American journalism awards
The National Pacemaker Awards are awards for excellence in American student journalism, given annually since 1927. The awards are generally considered
National_Pacemaker_Awards
Applied science and research
needs, resulting in creations such as bridges, engines, smartphones, pacemakers, the internet, spacecraft, and washing machines. Engineering involves
Engineering
Irish tax-registered medical device company
systems. They also created miniaturized devices like the world's smallest pacemaker and spinal cord stimulator. Medtronic was founded in 1949 in Minneapolis
Medtronic
Medical imaging procedure
of a body. CT scans can be used in patients with metallic implants or pacemakers, for whom magnetic resonance imaging (MRI) is contraindicated. Since its
CT_scan
Purposeful modulation of nervous system activity
"Implantable pacemaker for the heart". In Smyth CN (ed.). Medical electronics. Paris: Iliffe & Sons. Warren J, Nelson J (2000). "Pacemakers and ICD pulse
Neurostimulation
Failure of the heart to provide sufficient blood flow
shortness of breath. Depending on the case, an implanted device such as a pacemaker or implantable cardiac defibrillator may sometimes be recommended. In
Heart_failure
Country in North America
major Canadian scientific contributions include the artificial cardiac pacemaker, mapping the visual cortex, the development of the electron microscope
Canada
Chemical compound
developed in the 1970s and 1980s. It causes bradycardia by inhibiting the pacemaker current by altering the maximal channel conductance and alter the voltage
Alinidine
Physiological reaction or injury caused by electric current
directly to the heart i.e. a pacemaker lead, or a guide wire, conductive catheter etc. connected to a source of current. This is a largely theoretical
Electrical_injury
American physician (1934–2023)
for his work and research in the diagnostic cardiac ultrasound, heart pacemakers, exercise stress testing, and heart catheterization. He was the president
Riaz_Haider
Chest discomfort due to disorder of the heart muscles
PMID 17387127. Tobin KJ (July 2010). "Stable angina pectoris: what does the current clinical evidence tell us?". The Journal of the American Osteopathic Association
Angina
Infectious disease caused by Borrelia bacteria, spread by ticks
sleeping. About a third of people with Lyme carditis need a temporary pacemaker until their heart conduction abnormality resolves, and 21% need to be
Lyme_disease
Irregular beating of the atria of the heart
of the heart allows electrical impulses generated by the heart's own pacemaker (the sinoatrial node) to spread to and stimulate the muscular layer of
Atrial_fibrillation
Reduction of blood flow to the heart
(April 2014). "Screening low-risk individuals for coronary artery disease". Current Atherosclerosis Reports. 16 (4) 402. doi:10.1007/s11883-014-0402-8. PMID 24522859
Coronary_artery_disease
man with severe chest pains who needs urgent medical attention and a pacemaker, but the patient states his desire is to die. Ultimately, Jared chooses
List of The Good Doctor episodes
List_of_The_Good_Doctor_episodes
Association football club in England
musical Carousel and later recorded by Liverpool musicians Gerry and the Pacemakers, is the club's anthem and has been sung by the Anfield crowd since the
Liverpool_F.C.
Teddy Boy The Back Seat of My Car Jimmy McCracklin The Walk Gerry and the Pacemakers Don't Let the Sun Catch You Crying Carl Perkins Blue Suede Shoes Gone
The Beatles' recording sessions
The_Beatles'_recording_sessions
Medical intervention
device to the commercial market in the early 1970s. The Avery Breathing Pacemaker received pre-market approval from the FDA in 1987 for "chronic ventilatory
Diaphragm_pacing
Newspaper in Auburn, Alabama
decorated non-weekly print student publication in the history of the National Pacemaker competition. As of February 2021, the Plainsman is primarily an online
The_Auburn_Plainsman
Head of the Catholic Church from 2005 to 2013
had been fitted with a pacemaker while he was still a cardinal, before his election as pope in 2005. The battery in the pacemaker had been replaced three
Pope_Benedict_XVI
American cardiologist (1911–1999)
and one of the pioneers in the development of the artificial cardiac pacemaker and cardiac defibrillator. Zoll's parents were Hyman and Mollie Zoll.
Paul_Zoll
Warm-blooded animals with wings and feathers
during contraction. Being myogenic, the heart's pace is maintained by pacemaker cells found in the sinoatrial node, located on the right atrium. The sinoatrial
Bird
Swedish surgeon
pacemaker, 1958 Copy of the first implantable heart pacemaker First commercial heart pacemaker (Elema-Schönander), 1960–61 Commercial heart pacemaker
Åke_Senning
Independent student newspaper of the Pennsylvania State University
States receiving multiple notable journalism awards including National Pacemaker Awards, top rankings from The Princeton Review, and Sigma Delta Chi Awards
Daily_Collegian
2019 attempt to beat a 2-hour marathon
May 2019. 41 pacemakers, rotating in and out in groups of 7, assisted Kipchoge throughout the attempt. Due to the presence of the pacemakers, delivery of
Ineos_1:59_Challenge
2020 studio album by Stray Kids
Sales)". Billboard. Retrieved July 16, 2023. "Stray Kids Chart History (Top Current Album Sales)". Billboard. Retrieved July 16, 2023. [dead link] "Stray Kids
Go_Live_(album)
Rapid quivering of the ventricles of the heart
myocardial cells. These may then act as pacemakers. The ventricles are then being stimulated by more than one pacemaker. Scar and dying tissue is inexcitable
Ventricular_fibrillation
Examination of the heart's electrical activity
healthy heart has an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads throughout the atrium, and passes
Electrocardiography
Sudden or unexpected loss of heartbeat
Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): developed in collaboration with the American
Cardiac_arrest
American distance runner (born 1955)
former professional distance runner and current businessman. In 1981, when running as a designated pacemaker or 'rabbit' in the high-profile 1500 meters
Tom_Byers_(runner)
Study of heart disorders
field include antiarrhythmic drug therapy and surgical implantation of pacemakers and implantable cardioverter-defibrillators. Common rhythms dealt with
Clinical cardiac electrophysiology
Clinical_cardiac_electrophysiology
City in Merseyside, England
originated in the city including Billy J. Kramer, Cilla Black, Gerry and the Pacemakers and the Searchers. The influence of musicians from Liverpool, coupled
Liverpool
Train system using magnetic levitation
electromagnetic propulsion was by attraction of iron in the train by direct current solenoids spaced along the track. The electromagnetic levitation was due
Maglev
Cluster of interneurons in the medulla oblongata
activity of pacemaker neurons through sodium current activation. Hypoxia results in gasping due to the increased dependence on the sodium current and the
Pre-Bötzinger_complex
Prime Minister of Israel (1996–1999; 2009–2021; 2022–present)
removed a small colon polyp that proved to be benign. On 22 July 2023, a pacemaker was implanted in his body. A hernia was discovered on him in March 2024
Benjamin_Netanyahu
Medical device
implantation of an ICD system is similar to implantation of an artificial pacemaker. The first component or generator contains a computer chip or circuitry
Implantable cardioverter-defibrillator
Implantable_cardioverter-defibrillator
C.H. (Positive Approach to Changing Humans) c-16m July 23, 1970 Video Pacemakers and Your Heart Rhythm c-13m 1982 Cardiology: You & Your Heart The Pacific
List_of_Coronet_Films_films
President of South Africa from 1989 to 1994
biggest known South African that has ever lived." De Klerk received a pacemaker in July 2013. Upon hearing of the death of Mandela, de Klerk said: "He
F._W._de_Klerk
Medical condition
is the heart's "pacemaker". The electrical activity of sinus rhythm originates in the sinoatrial node and depolarizes the atria. Current then passes from
Junctional_rhythm
Hybrid compact car produced by Toyota
Mayo Clinic found that patients with implanted cardiac devices such as pacemakers and defibrillators can safely drive or ride in hybrids or plug-in electric
Toyota_Prius
Protein-coding gene in the species Homo sapiens
Robinson RB (September 2013). "An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia". Journal of Cardiovascular
KCNE2
Blood clot within the heart's blood vessels
myocardial infarction over a 15-year period. There are numerous treatments currently being studied for management and prevention of coronary thrombosis. Statin
Coronary_thrombosis
Naturally recurring resting state of mind and body
not) and drops to almost nothing during subjective night. The circadian pacemaker in the suprachiasmatic nucleus has a direct neural connection to the pineal
Sleep
Country in South America
medicine have been made in Colombia, such as the first external artificial pacemaker with internal electrodes, invented by the electrical engineer Jorge Reynolds
Colombia
Monoamine neurotransmitter
(November 2016). "SERCA2a was serotonylated and may regulate sino-atrial node pacemaker activity". Biochemical and Biophysical Research Communications. 480 (3):
Serotonin
British multi-role combat aircraft of WW2
Vancouver Vanessa Varuna Vedette Velos Vigil Vista Avro 504N Avro 552 CH-300 Pacemaker PBV-1 Canso HS-3L FC-2 Super Universal Delta Stranraer Viking IV Cub Aircraft
De_Havilland_Mosquito
Autoimmune disease resulting in uncontrollable jerking motions
Raymund A.C. (July 2010). "Sydenham's Chorea: A Practical Overview of the Current Literature". Pediatric Neurology. 43 (1): 1–6. doi:10.1016/j.pediatrneurol
Sydenham's_chorea
President of Poland from 1990 to 1995
underwent a coronary artery stent placement and the implantation of a cardiac pacemaker at the Houston Methodist Hospital in Houston, Texas. He underwent a heart
Lech_Wałęsa
Electrical generator that uses heat from radioactive decay
number was reported to be down to just nine. The Mound Laboratory Cardiac Pacemaker program began on 1 June 1966, in conjunction with NUMEC. The program was
Radioisotope thermoelectric generator
Radioisotope_thermoelectric_generator
Sexual practice
cardiac arrest), and this risk is higher for those who use an artificial pacemaker or similar device or who have heart conditions. A few cases of accidental
Erotic_electrostimulation
Drug mixture used mainly to treat ADHD and narcolepsy
interval timing, leading to the hypothesis that dopamine influences internal pacemaker, or "clock," activity. For instance, amphetamine, which increases concentrations
Adderall
President of Italy since 2015
Festival. On 15 April 2025, Mattarella underwent heart surgery to have a pacemaker fitted. Italian pronunciation: [ˈsɛrdʒo mattaˈrɛlla]. Elected in a closed
Sergio_Mattarella
later time. This contrasts with pacemaker potential or current which drives rhythmic modulation of firing rate. Some pacemaker action generate rhythms for
Pacemaker_action_potential
Complications resulting from surgical incision of the pericardium
placement after a myocardial infarction or heart attack), or due to pacemaker or pacemaker wire placement. The typical signs of post-pericardiotomy syndrome
Postpericardiotomy_syndrome
Australian musician and actor (born 1953)
He was diagnosed as having a heart arrhythmia and was fitted with a pacemaker at Sydney's Mater Hospital. His surgery was "urgent but routine" and Fatt
Jeff_Fatt
Chemical element with atomic number 46 (Pd)
& Keilberth, Richard et al., "Electrode connecting cable for cardiac pacemaker", issued 30 April 1985 Gupta, Dinesh C.; Langer, Paul H.; ASTM Committee
Palladium
British rock band (1961–1984)
Anniversary of the British Rock 'N' Roll Tour", which included Gerry and the Pacemakers, the Troggs, Billy J. Kramer and Herman's Hermits. In 1986, Molland and
Badfinger
Long-distance running event of 42.195 kilometres
versus Horse Marathon Marathons at the Paralympics Other related topics Pacemaker (running) Physiology of marathons This date is specified as 10 March in
Marathon
Sudden temporary weakening of the heart muscle
Retrieved 27 May 2017. McPhee SJ, Rabow MW, Papadakis MA (1 September 2016). Current medical diagnosis & treatment 2017 (Fifty-sixth ed.). New York: McGraw
Takotsubo_cardiomyopathy
Object that has a magnetic field
different type of indirect magnetic health risk exists involving pacemakers. If a pacemaker has been embedded in a patient's chest (usually for the purpose
Magnet
Organ system within humans and other animals
myenteric plexus. This controls peristalsis. Activity is initiated by the pacemaker cells, (myenteric interstitial cells of Cajal). The gut has intrinsic
Gastrointestinal_tract
Natural internal process that regulates the sleep-wake cycle
involved both as a photoreceptor and as part of the clock's endogenous pacemaker mechanism. Cryptochromes 1–2 (involved in blue–UVA) help to maintain the
Circadian_rhythm
Abnormally fast heart rhythm
small (1%) incidence of injuring the AV node, then requiring a permanent pacemaker. Cryoablation uses a catheter supercooled by nitrous oxide gas freezing
Supraventricular_tachycardia
Disease of the heart muscle
may include medication (conservative treatment) or iatrogenic/implanted pacemakers for slow heart rates, defibrillators for those prone to fatal heart rhythms
Cardiomyopathy
CNS stimulant and isomer of amphetamine
interval timing, leading to the hypothesis that dopamine influences internal pacemaker, or "clock," activity. For instance, amphetamine, which increases concentrations
Dextroamphetamine
Finding in electrocardiograms
caused by pacemakers are normal as well, but if they occur too frequently may reduce cardiac output and so can require adjustment of the pacemaker. Understanding
Fusion_beat
Therapeutic technique
essential tremor and is currently marketed as Cala Trio. People who have implanted electronic medical devices including pacemakers and cardiodefibrillators
Transcutaneous electrical nerve stimulation
Transcutaneous_electrical_nerve_stimulation
Medical condition
of TTR amyloidosis. Ten to 20% of those with ATTR amyloidosis required pacemakers, usually due to high degree atrioventricular blocks. Observational cohort
Cardiac_amyloidosis
Volcanic supereruption 74,000 years ago in Indonesia
John; Shackleton, N. J. (1976-12-10). "Variations in the Earth's Orbit: Pacemaker of the Ice Ages: For 500,000 years, major climatic changes have followed
Youngest_Toba_eruption
PACEMAKER CURRENT
PACEMAKER CURRENT
Boy/Male
Muslim
Peacemaker
Girl/Female
Tamil
Peacemaker, Who is calm and disciplined
Girl/Female
Muslim
Peacemaker
Boy/Male
Arabic
Peacemaker; Mediator
Girl/Female
Tamil
Peacemaker, Who is calm and disciplined
Surname or Lastname
English (Norfolk)
English (Norfolk) : diminutive of Platt 1.English (Norfolk) : metonymic occupational name for a platemaker, from Old French platon ‘metal plate’.
Girl/Female
Hindu
Peacemaker
Boy/Male
Arabic
Peacemaker; Mediator
Boy/Male
Hindu
Peacemaker
Girl/Female
Hindu
Peacemaker, Who is calm and disciplined
Boy/Male
Hindu, Indian, Malayalam, Marathi
Peacemaker
Girl/Female
Indian, Swedish
Quiet; Peacemaker
Girl/Female
Hindu
Peacemaker, Who is calm and disciplined
Girl/Female
Tamil
Peacemaker, Who is calm and disciplined
Boy/Male
American, Australian, British, Christian, English, French, German, Polish, Slavic
Peacemaker; From a Polish Word; Proclamation of Peace; Someone who Destroys Opponent's Prestige; Glory During Battle
Girl/Female
Hindu
Peacemaker, Who is calm and disciplined
Girl/Female
Tamil
Peacemaker
Boy/Male
Christian & English(British/American/Australian)
Peacemaker
Girl/Female
Arabic, Muslim
Peacemaker
Boy/Male
Tamil
Peacemaker
PACEMAKER CURRENT
PACEMAKER CURRENT
Girl/Female
Indian
Sweet Smiling; Rose
Boy/Male
Tamil
Lord Krishna
Girl/Female
Tamil
Intellect, Desire, Wish, Goddess of mind
Male
English
Pet form of English Ralph, RALPHIE means "wise wolf."
Biblical
he that measures; water of love
Girl/Female
Indian, Telugu
Scented Ion
Girl/Female
Hindu, Indian, Malayalam, Tamil, Telugu
Hymn; The Writing of the Vedas; Lucky
Boy/Male
Assamese, British, English, French, Gujarati, Hindu, Indian, Indonesian, Kannada, Malayalam, Marathi, Mythological, Telugu
Powerful; Mighty Monkey King of Kiskindha; Monkey King; Brave; Lord of Strength
Boy/Male
American, Australian, British, Celebrity, Danish, English, French, German, Indian, Italian, Portuguese, Spanish, Swiss, Tamil
An Expert with the Spear
Boy/Male
Tamil
Brihatbrahma | பà¯à®°à¯€à®¹à®¾à®¤à¯à®ªà¯à®°à®¹à¯à®®à®¾
Son of sage Agniras
PACEMAKER CURRENT
PACEMAKER CURRENT
PACEMAKER CURRENT
PACEMAKER CURRENT
PACEMAKER CURRENT
v. i.
To do work for a less price than current rates.
n.
An instrument for the exact measurement of electric currents.
a.
Passing from person to person, or from hand to hand; circulating through the community; generally received; common; as, a current coin; a current report; current history.
a.
Of or pertaining to Alessandro Volta, who first devised apparatus for developing electric currents by chemical action, and established this branch of electric science; discovered by Volta; as, voltaic electricity.
n.
One who, or that which, pacifies; a peacemaker.
n.
A peacemaker.
adv.
Toward the higher part of a stream; against the current.
n.
One who makes peace by reconciling parties that are at variance.
n.
A blood-sucking ghost; a soul of a dead person superstitiously believed to come from the grave and wander about by night sucking the blood of persons asleep, thus causing their death. This superstition is now prevalent in parts of Eastern Europe, and was especially current in Hungary about the year 1730.
a.
General course; ordinary procedure; progressive and connected movement; as, the current of time, of events, of opinion, etc.
adv.
In a current manner; generally; commonly; as, it is currently believed.
n.
A train of association, thoughts, emotions, or the like; a current; a course.
n.
One who, or that which, makes a way or path.
a.
Passing through the air upon wings, or as if upon wings; flying; hence, passing from place to place; current.
n.
A wave or current of wind.
n.
The unit of electro-motive force; -- defined by the International Electrical Congress in 1893 and by United States Statute as, that electro-motive force which steadily applied to a conductor whose resistance is one ohm will produce a current of one ampere. It is practically equivalent to / the electro-motive force of a standard Clark's cell at a temperature of 15¡ C.
a.
Now passing, as time; as, the current month.
n.
The quality of being current; currency; circulation; general reception.
a.
A flowing or passing; onward motion. Hence: A body of fluid moving continuously in a certain direction; a stream; esp., the swiftest part of it; as, a current of water or of air; that which resembles a stream in motion; as, a current of electricity.