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Class of neurotransmitters
Gasotransmitters is a class of neurotransmitters. The molecules are distinguished from other bioactive endogenous gaseous signaling molecules based on
Gasotransmitter
Poisonous gas consisting of carbon and oxygen
where low concentrations serve as an endogenous neurotransmitter (gasotransmitter) and high concentrations are toxic, resulting in carbon monoxide poisoning
Carbon_monoxide
Set of chemical reactions in organisms
this gas is poisonous to some animals. Since hydrogen sulfide is a gasotransmitter, certain mammals including humans produce H₂S naturally in very small
Metabolism
Poisonous and flammable gas
"Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter". Nature Reviews Drug Discovery. 14 (5): 329–345. Bibcode:2015NRvDD
Hydrogen_sulfide
English socialite, activist, and author (1757–1806)
framework for modern anesthesia as well as modern biomedical research in gasotransmitters. As was common among the aristocracy of her time, Georgiana routinely
Georgiana Cavendish, Duchess of Devonshire
Georgiana_Cavendish,_Duchess_of_Devonshire
Medical condition of lack of oxygen in the tissues
ISBN 978-1-4614-7542-2. Prabhakar, Nanduri R.; Peers, Chris (2014). "Gasotransmitter Regulation of Ion Channels: A Key Step in O2Sensing by the Carotid
Hypoxia_(medicine)
Chemical substance that enables neurotransmission
glutamate, aspartate, D-serine, gamma-aminobutyric acid (GABA), glycine Gasotransmitters: nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H2S) Monoamines:
Neurotransmitter
Organic compounds with a –COOH group and a C=O group
phenylpyruvic acid are endogenous sources for carbon monoxide (as a gasotransmitter) and pharmaceutical prodrug scaffold. Important representatives: pyruvic
Keto_acid
Molecular gases which transmit information
gaseous signaling molecules behave as neurotransmitters and are called gasotransmitters. These include nitric oxide, carbon monoxide, and hydrogen sulfide
Gaseous_signaling_molecules
Substances delivering CO within the body
toxicity in carbon monoxide poisoning at high doses. However, CO is a gasotransmitter and supplemental low dosage of CO has been linked to therapeutic benefits
Carbon monoxide-releasing molecules
Carbon_monoxide-releasing_molecules
Toxic effects of carbon monoxide
it can serve as an important neurotransmitter (subcategorized as a gasotransmitter) and a potential therapeutic agent. In the case of prokaryotes, some
Carbon_monoxide_poisoning
Characteristic of biological processes
it has essential roles as a neurotransmitter (subcategorized as a gasotransmitter). The majority of endogenous carbon monoxide is produced by heme oxygenase;
Hormesis
Inorganic anion containing one sulfur and one hydrogen atoms
to mean, bisulfide. Hydrosulfide has been identified as the third gasotransmitter along with nitric oxide and carbon monoxide. It has a pKa of 6.9: Upon
Bisulfide
Scottish philosopher and physician (1736–1812)
monster". Lind's discovery is a significant origin for the field of gasotransmitters in the context of carbon monoxide's neurotransmitter properties and
James_Lind_(naturalist)
Medical condition
hydrogen sulfide. Hydrogen sulfide (H2S) works as a vasculoprotective gasotransmitter in the human body but is also tested to reduced intimal hyperplasia
Intimal_hyperplasia
Study of biologically active molecules that contain carbon-metal bonds
actively investigated, due to the importance of carbon monoxide as a gasotransmitter. Within the realm of bioorganometallic chemistry is the study of the
Bioorganometallic_chemistry
Protein containing a heme prosthetic group
biologic systems (cells), these gaseous molecules are referred to as gasotransmitters. Because of their diverse biological functions and widespread abundance
Hemoprotein
Species of archaeon
colonic and ileal smooth muscle and a possible role for methane as a gasotransmitter. Statins can inhibit archaeal cell membrane biosynthesis apparently
Methanobrevibacter_smithii
Complex of carbon monoxide and hemoglobin
a neurotransmitter in 1993 and has since been subcategorized as a gasotransmitter. Most endogenously produced carbon monoxide is stored as carboxyhemoglobin
Carboxyhemoglobin
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
List_of_MeSH_codes_(D01)
signaling by receiving (binding to) gaseous signaling molecules or gasotransmitters. They are specialized proteins that allow communication within and
Gas_sensor_protein
Voltage-gated potassium channel protein
been found to be activated by exogenous pollutants and endogenous gasotransmitters carbon monoxide and hydrogen sulphide. BK channels are blocked by tetraethylammonium
Calcium-activated potassium channel subunit alpha-1
Calcium-activated_potassium_channel_subunit_alpha-1
American chemist
β-synthase, the enzyme responsible for biosynthesis of the important "gasotransmitter" H2S in the brain, and human serine racemase, the enzyme that controls
David_B._Berkowitz
Hungarian physician and pharmacologist
biological roles of small diffusible, unstable gaseous molecules (gasotransmitters) in health and disease. His early work focused on the role of the gaseous
Csaba_Szabo_(pharmacologist)
Family of transport proteins
BK channels can be activated by exogenous pollutants and endogenous gasotransmitters carbon monoxide, nitric oxide, and hydrogen sulphide. Mutations in
BK_channel
Historical science of gases
Rahman MA, Reddy D, et al. (September 2016). "The emerging role of gasotransmitters in the pathogenesis of tuberculosis". Nitric Oxide. 59: 28–41. doi:10
Factitious_airs
Protein-coding gene in the species Homo sapiens
for which some other PHD-inhibitors show overlapping specificity. Gasotransmitters including carbon monoxide and nitric oxide are also inhibitors of PHD2
EGLN1
Hermann, Anton; Sitdikova, Guzel F.; Weiger, Thomas M., eds. (2012). Gasotransmitters: Physiology and Pathophysiology. Berlin, Heidelberg: Springer Berlin
Gaseous_mediator
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