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Enzyme of the glycolysis metabolic pathway
dehydrogenase, testis-specific is an enzyme that in humans is encoded by the GAPDHS gene. This gene encodes a protein belonging to the glyceraldehyde-3-phosphate
GAPDHS
Enzyme of the glycolysis metabolic pathway
In sperm, a testis-specific isoenzyme GAPDHS is expressed. Under normal cellular conditions, cytoplasmic GAPDH exists primarily as a tetramer. This form
Glyceraldehyde 3-phosphate dehydrogenase
Glyceraldehyde_3-phosphate_dehydrogenase
Study of chemical processes of living organisms
Glucose G6P F6P F1,6BP GADP DHAP 1,3BPG 3PG 2PG PEP Pyruvate HK PGI PFK ALDO TPI GAPDH PGK PGM ENO PK Glycolysis
Biochemistry
Series of interconnected biochemical reactions
Glucose G6P F6P F1,6BP GADP DHAP 1,3BPG 3PG 2PG PEP Pyruvate HK PGI PFK ALDO TPI GAPDH PGK PGM ENO PK Glycolysis
Glycolysis
Drug developed by Novartis
dehydrogenase (GAPDH) and SIAH1. The glycolytic housekeeping enzyme GAPDH is mediated by neuronal nitric oxide synthase. Once activated by nitric oxide, GAPDH binds
Omigapil
Monoamine neurotransmitter
notable protein serotonylation substrates include several metabolic enzymes (GAPDH, mTOR), Rab GTPases (Rab3a, Rab27a), Rho GTPases (RhoA, Rac1, Cdc42), proteins
Serotonin
Set of biochemical reactions
cytosol, the latter reducing equivalent is used to drive the reversal of the GAPDH step instead of generating ATP. The fate of oxaloacetate is either to produce
Urea_cycle
Coenzyme, notable for its synthesis and oxidation role
different proteins (e.g., metastasis suppressor NME1, peroxiredoxin 5, GAPDH, among others) is reported. To restore the protein's activity, antioxidant
Coenzyme_A
RNA family
Glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) is a cellular enzyme typically involved in glycolysis. GAPDH is known to bind to the overlapping sites
Hepatitis A virus internal ribosome entry site (IRES)
Hepatitis_A_virus_internal_ribosome_entry_site_(IRES)
Species of wasp
activity of mastoparan from Polybia paulista wasp venom by interaction with TcGAPDH. Toxicon. Leite, Natália Bueno; Aufderhorst-Roberts, Anders; Palma, Mario
Polybia_paulista
Species of bird
suboscines. In an earlier analysis based on nDNA myoglobin intron 2 and GAPDH intron 11 sequence data, the authors found the sapayoa "as a deep branch
Sapayoa
Enzyme
uses glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and phosphoglycerate kinase to produce ATP. GAPDH is phosphorylating. GAPN is non-phosphorylating
Glyceraldehyde-3-phosphate dehydrogenase (NADP+)
Glyceraldehyde-3-phosphate_dehydrogenase_(NADP+)
Proposed eukaryotic kingdom
apicomplexan), heterokont and cryptophyte plastids based on their comparison of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) genes. Harper & Keeling (2003)
Chromista
Pregnancy prevention methods used by men
metabolic enzymes needed to power motility, such as Lactate Dehydrogenase C, GAPDHS, are also being evaluated as inhibition targets for developing male contraceptives
Male_contraceptive
Topics referred to by the same term
1.9) glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) (EC 1.2.7.6) GAPDHS (EC 1.2.1.12) This disambiguation page lists articles associated with the
Glyceraldehyde-3-phosphate dehydrogenase (disambiguation)
Glyceraldehyde-3-phosphate_dehydrogenase_(disambiguation)
Pharmacology of the antiparkinsonian and antidepressant selegiline
directly bind to and inhibit glyceraldehyde-3-phosphate dehydrogenase (GAPDH). This might play a modulating role in the clinical effectiveness of selegiline
Pharmacology_of_selegiline
Laboratory technique to multiply a DNA sample for study
Retrieved 24 April 2008. Park DJ (January 2005). "A new 5' terminal murine GAPDH exon identified using 5'RACE LaNe". Molecular Biotechnology. 29 (1): 39–46
Polymerase_chain_reaction
Protein that regulates the rate of DNA transcription
ubiquitous metabolic enzymes such as glyceraldehyde phosphate dehydrogenase (GAPDH)). E.g.: general transcription factors, Sp1, NF1, CCAAT II. Regulatory (conditionally
Transcription_factor
Family of transport proteins
multifunctional glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH, EC 1.2.1.12) has been shown to utilize post translational modifications
Transferrin_receptor
Iron metabolism in the body
ferroportin in effecting cellular iron export is GAPDH. A specific post translationally modified isoform of GAPDH is recruited to the surface of iron loaded
Human_iron_metabolism
Chemical process of introducing a phosphate
This reaction is catalyzed by glyceraldehyde-3-phosphate dehydrogenase (GAPDH). The phosphorylation of glucose to glucose 6-phosphate has role in regulating
Phosphorylation
Passerine bird family found across subtropical and tropical Central and South America
half the present species were known, comparison of the myoglobin intron 2, GAPDH intron 11 and the mtDNA cytochrome b DNA sequences has largely confirmed
Antbird
Conversion of a gene's sequence into a mature gene product or products
typically expressed in all cell types of an organism. Examples include actin, GAPDH and ubiquitin. Some housekeeping genes are transcribed at a relatively constant
Gene_expression
multifunctional glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been reported as a soluble receptor for transferrin. It has been demonstrated
Soluble_transferrin_receptor
Class of enzymes
dehydrogenase is not the same as glyceraldehyde 3-phosphate dehydrogenase (GAPDH), whose substrate is an aldehyde not an alcohol. GPDH plays a major role
Glycerol-3-phosphate dehydrogenase
Glycerol-3-phosphate_dehydrogenase
Post-translational modification
bisphosphate aldolase B (ALDOB) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Histone H2B Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) Very long-chain
Lysine_malonylation
Chemical compound
(KA, also known as heptelidic acid) is a potent, selective, irreversible GAPDH inhibitor. It is also a DNA polymerase inhibitor. The koningic acid molecule
Koningic_acid
Human chromosome
member A 19q13.11 DDX39: DExD-box helicase 39. Gene map locus 19p13.12 GAPDHS: glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 19q13.12 HAMP:
Chromosome_19
Chemical compound
glyceraldehyde-3-phosphate, which is catalyzed by glyceraldehyde phosphate dehydrogenase (GAPDH). The net production of ATP is zero as a result of the formation of the
1-Arseno-3-phosphoglycerate
Post-translational modification involving the monoamine serotonin
notable protein serotonylation substrates include several metabolic enzymes (GAPDH, mTOR), Rab GTPases (Rab3a, Rab27a), Rho GTPases (RhoA, Rac1, Cdc42), proteins
Serotonylation
should probably not be used for reference purposes: GUSB, RPLP0, TFRC, GAPDH, HSP90, and β-actin. Although they were once considered as "housekeeping
Reference_genes
Mammalian protein found in humans
associated protein 6, L-DOPA, EFCAB6, Epidermal growth factor receptor, FOXO1, GAPDH, Gelsolin, GNB2L1, GSK3B, HDAC1, HSP90AA1, HTATIP, MAGEA11, MED1, MYST2
Androgen_receptor
Cell-mediated killing of other cells mediated by antibodies
in which the contents of the lysed cells includes cellular enzymes like GAPDH that remain active; supplying a substrate for that enzyme can catalyze a
Antibody-dependent cellular cytotoxicity
Antibody-dependent_cellular_cytotoxicity
InterPro Family
interferon-gamma expression is regulated via GAPDH in T-cells. This interaction takes place in the 3'UTR, where binding of GAPDH prevents the translation of the mRNA
Interferon_gamma
that the protein has been loaded equally across all wells. "Beta Actin and GAPDH: The Importance of Loading Controls". 9 November 2011. "Loading controls"
Loading_control
Biomolecule
RNA-binding proteins, such as glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and NAD+ concentration is established, the NAD+ cap has been hypothesized
NAD+_Five-prime_cap
Chemical compound
dehydrogenase (GAPDH). This might play a modulating role in its clinical effectiveness for Parkinson's disease. Selegiline also binds to and inhibits GAPDH. Rasagiline
Rasagiline
Protein-coding gene in humans
are two proteins (GAPDHS and GOLGA2) that interact with C12orf50. Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (GAPDHS) enzyme may play an
C12orf50
Mammalian protein found in Homo sapiens
moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been demonstrated to function as a receptor for lactoferrin. Ribonuclease-enriched
Lactoferrin
Use of Iron by organisms
ferroportin in effecting cellular iron export is GAPDH. A specific post translationally modified isoform of GAPDH is recruited to the surface of iron loaded
Iron_in_biology
Protein family
activity of mastoparan from Polybia paulista wasp venom by interaction with TcGAPDH. Toxicon. Irazazabal, Luz N.; Porto, William F.; Ribeiro, Suzana M.; Casale
Mastoparan
Laboratory process
PCR is performed using Sry-specific primers. A housekeeping gene such as Gapdh is co-amplified to confirm PCR success and ensure accurate interpretation
Genotyping
Genus of dinoflagellates
function to target the new green algae plastid. L. chlorophorum possesses the GAPDH which is a plastid-targeted gene originated from a haptophyte, an alga taken
Lepidodinium
Family of viruses
Tombusviridae have been found to co-opt GAPDH, a host metabolic enzyme, for use in the replication center. GAPDH may bind to the (−)RNA strand and keep
Tombusviridae
Biological protein kinase C inhibitor
PKCiota/lambda phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPDH) that sort cargo to the anterograde pathway the phosphorylation pathway(s)
BIM-1
Protein family
kinase acting in series with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in gluconeogenesis, and in series with glyceraldehyde-3-phosphate dehydrogenase
Fructose-bisphosphate aldolase
Fructose-bisphosphate_aldolase
Metabolic process
(Fbp1) and a glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (Gapdh) are highly expressed in gas gland cells. The study signified that the characterization
Futile_cycle
Proteins performing more than one function
1002/mas.20041. PMID 15605385. Seidler NW (2013). "Basic Biology of GAPDH". GAPDH: Biological Properties and Diversity. Advances in Experimental Medicine
Protein_moonlighting
Species of protist
Ken-ichiro; Archibald, John M. (2012-12-20). "Broad Distribution of TPI-GAPDH Fusion Proteins among Eukaryotes: Evidence for Glycolytic Reactions in the
Thecamonas_trahens
oxygenase activase, which regulates the photosynthetic enzyme RuBisCO, GAPDH, which is involved in glycolysis and oxidative stress response, as well
Reverse_northern_blot
GANC HGNC:4139; Q8TET4 6060 GAP43 HGNC:4140; P17677 6061 GAPDH HGNC:4141; P04406 6062 GAPDHS HGNC:24864; O14556 6063 GAPT HGNC:26588; Q8N292 6064 GAPVD1
List of human protein-coding genes 3
List_of_human_protein-coding_genes_3
Genus of lichen
"Monophyletic groups within the Parmeliaceae identified by ITS rDNA, β-tubulin and GAPDH sequences". Mycological Progress. 3 (4): 297–314. doi:10.1007/s11557-006-0100-1
Cetrariella
Investigational Parkinson's disease drugs
(CGP-3466; SNT-317; TCH-346) – glyceraldehyde 3 phosphate dehydrogenase (GAPDH) inhibitor [282] OPM-201 (S-221237) – leucine-rich repeat kinase 2 (LRRK2)
List of investigational Parkinson's disease drugs
List_of_investigational_Parkinson's_disease_drugs
Medical condition
weakness and muscle wasting). Step 6 Glyceraldehyde 3-phosphate dehydrogenase GAPDH 138400 Brain Unclear role in: Alzheimer's Huntington's Parkinson's Neurodegeneration
Inborn errors of carbohydrate metabolism
Inborn_errors_of_carbohydrate_metabolism
Species of lichen
"Monophyletic groups within the Parmeliaceae identified by ITS rDNA, β-tubulin and GAPDH sequences". Mycological Progress. 3 (4): 297–314. doi:10.1007/s11557-006-0100-1
Melanohalea_zopheroa
Analysis technique of genes
used for normalization. The most commonly used house keeping genes include GAPDH and α-actin, although the reliability of normalization through this process
Single-cell_transcriptomics
the type of stain. Housekeeping genes and proteins, including β-Actin, GAPDH, HPRT1, and RPLP1, are often used as internal controls in western blots
Western_blot_normalization
American scientist
Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product". Cell Metabolism. 26 (4): 648–659.e8
Jason_Locasale
released intracellular enzymes: dead cells release enzyme (e.g. LDH or GAPDH) and addition of its substrate leads to color change, that is usually quantified
Complement-dependent cytotoxicity
Complement-dependent_cytotoxicity
phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating) GAPDH glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide
Glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
Glyceraldehyde-3-phosphate_dehydrogenase_(NADP+)_(phosphorylating)
Protein-coding gene in the species Homo sapiens
GSPT2, NAA38, RNMT, CSNIK1G2, ACOX1, PSMC1, SLC25A37, MMS19, DIAPH1, ME1, GAPDH, UBC. After performing a yeast two-hybrid screen, it was found that NAA38
MINDY1
Genus of lichen
"Monophyletic groups within the Parmeliaceae identified by ITS rDNA, β-tubulin and GAPDH sequences". Mycological Progress. 3 (4): 297–314. doi:10.1007/s11557-006-0100-1
Melanohalea
Chemical compound
found to bind to and inhibit glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which may be involved in their neuroprotective effects. Selegiline and
Desmethylselegiline
Post-translational modifications involving monoamines
Wei-Ting; Zuo, Hao; Du, Chang; Yao, Lin-Li; Li, Hui; Li, Jun (2024-02-15). "A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor
Monoaminylation
Biochemical reaction; attachment of –NO to cysteine in a protein
Whorton AR (September 1995). "S-nitrosoglutathione reversibly inhibits GAPDH by S-nitrosylation". The American Journal of Physiology. 269 (3 Pt 1): C739–C749
S-Nitrosylation
Protein-coding gene in the species Homo sapiens
protein interact with a number of other proteins including SSSCA1, TSSC1, GAPDH, NUP98 and SNAI1. Source: FLJ25737 mRNA sequences perfectly match with two
QRICH2
Protein-coding gene in the species Homo sapiens
Youichiro; Kodama Tatsuhiko; Doi Takefumi (Jan 2002). "HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors"
MSR1
Situation where tumor cells have been deprived of oxygen
fructose-bisphosphate aldolase (ALDO), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), phosphoglycerate kinase (PGK), phosphoglycerate mutase (PGM), enolase
Tumor_hypoxia
Protein-coding gene in the species Homo sapiens
Imanishi T, Wada Y, Kodama T, Doi T (January 2002). "HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors"
HSPA1A
produced within the glycolytic glyceraldehyde 3-phosphate dehydrogenase (GAPDH; EC 1.2.1.9) reaction. Glutamate and fatty acids are immunosuppressive.
Glutaminolysis
Class of protozoans
Keeling, P. J. (2001). "Diplonemid Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Prokaryote-to-Eukaryote Lateral Gene Transfer". Protist. 152 (3): 193–201
Diplonemid
Genus of lichen
"Monophyletic groups within the Parmeliaceae identified by ITS rDNA, β-tubulin and GAPDH sequences". Mycological Progress. 3 (4): 297–314. doi:10.1007/s11557-006-0100-1
Coelopogon
Species of archaeon
to amino acid metabolism. M. burtonii have increased levels of GDH and GAPDH (key enzymes in nitrogen and carbon metabolism) at 4 °C indicating that
Methanococcoides_burtonii
Swedish lichenologist
groups within the Parmeliaceae identified by ITS rDNA, betatubulin and GAPDH sequences". Mycological Progress. 3 (4): 297–314. Bibcode:2004MycPr...3
Ingvar_Kärnefelt
Protein-coding gene in the species Homo sapiens
this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway
PRKCI
Fungal species
regions such as the internally transcribed spacer (ITS), or introns in the GAPDH, histone3, beta-tubulin, or actin genes. Like other species in the C. acutatum
Colletotrichum_fioriniae
Blood parasite of koalas named after Steve Irwin
Trypanosoma ssp. and T. irwini using partial sequence analysis of 18S rDNA and gGAPDH Phylogenetic analysis of Trypanosoma ssp. and T. irwini using partial sequence
Trypanosoma_irwini
Indian biologist
Shabir Ahmad; Kumar, Ashwani (18 January 2021). "Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy"
Ashwani_Kumar_(scientist)
Protein family
ankyrin, protein 4.2, protein 4.1, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), phosphofructokinase, aldolase, hemoglobin, hemichromes, and the protein
Anion_exchanger_family
Protein-coding gene in the species Homo sapiens
Nathan H. Lents showed that MZF-1 induces the GAPDH gene, something that must be considered when GAPDH is used as a loading control in experiments that
MZF1
Genus of fungi
Monophyletic groups within the Parmeliaceae identified by ITS rDNA, β-tubulin and GAPDH sequences. Mycological Progress 3: 297-314. https://doi.org/10.1007%2Fs11557-006-0100-1
Menegazzia
Protein-coding gene in the species Homo sapiens
the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component". Cell. 114 (2): 255–66. doi:10.1016/S0092-8674(03)00552-X
NPAT_(gene)
mice treated had noticeable tumors around the implantation site. Even so, GAPDH, a tumor-derived signal, was present at low levels, indicating significant
Stable nucleic acid lipid particle
Stable_nucleic_acid_lipid_particle
GAPDHS
GAPDHS
GAPDHS
GAPDHS
Male
Spanish
Spanish form of German Harmand, ARMANDO means "bold/hardy man."
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit
Lotus
Female
Native American
Native American Omaha name NIDAWI means "fairy."
Boy/Male
Hindu, Indian
Chief; Leader
Girl/Female
Australian, Jamaican
God will Add
Girl/Female
Tamil
Premila | பà¯à®°à¯‡à®®à¯€à®²à®¾
Queen of a womens kingdom
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Mythological, Sanskrit, Sindhi, Tamil, Telugu
Name of Indra; King of Andhra
Biblical
my son; my corn
Boy/Male
Assamese, Hindu, Indian, Kannada, Marathi, Oriya, Telugu
A Raga
Boy/Male
Indian, Sanskrit
Promoter of Happiness
GAPDHS
GAPDHS
GAPDHS
GAPDHS
GAPDHS