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EEA1

  • EEA1
  • Protein-coding gene in humans

    The gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role

    EEA1

    EEA1

    EEA1

  • FYVE domain
  • Protein family

    (yeast orthologue of PIKfyve), YOTB, Vac 1 (vesicle transport protein), and EEA1, in which it has been found. FYVE domains bind phosphatidylinositol 3-phosphate

    FYVE domain

    FYVE domain

    FYVE_domain

  • Endosome
  • Vacuole to which materials ingested by endocytosis are delivered

    diameter). Markers include RAB5A and RAB4, Transferrin and its receptor and EEA1. Late endosomes, also known as MVBs, are mainly spherical, lack tubules,

    Endosome

    Endosome

    Endosome

  • Phosphatidylinositol 3-phosphate
  • Chemical compound

    Both FYVE domains and PX domains – found in proteins such as SNX1, HGS, and EEA1 – bind to PtdIns3P. The majority of PtdIns3P appears to be constitutively

    Phosphatidylinositol 3-phosphate

    Phosphatidylinositol 3-phosphate

    Phosphatidylinositol_3-phosphate

  • Mycobacterium tuberculosis
  • Bacterium that causes tuberculosis

    tuberculosis blocks the bridging molecule, early endosomal autoantigen 1 (EEA1); however, this blockade does not prevent fusion of vesicles filled with

    Mycobacterium tuberculosis

    Mycobacterium tuberculosis

    Mycobacterium_tuberculosis

  • List of human transcription factors
  • ENSG00000088881 EBF1 Known motif – In vivo/Misc source [183] CGSATAACCMTTGTTATCAB EEA1 ENSG00000102189 C2H2 ZF Likely sequence specific TF according to literature

    List of human transcription factors

    List_of_human_transcription_factors

  • Baltimore Orioles minor league players
  • com/sports/local_sports/moondogs-closer-working-on-control/article_cdb3816a-eea1-11ec-8c5b-b735db69512a.html https://www.cjonline.com/story/sports/colleg

    Baltimore Orioles minor league players

    Baltimore_Orioles_minor_league_players

  • Immigration (European Economic Area) Regulations
  • Application Applicant Result valid for VAF5 non-EEA EEA family permit 6 months EEA1 EEA registration certificate 5 years or envisaged period of residence if

    Immigration (European Economic Area) Regulations

    Immigration_(European_Economic_Area)_Regulations

  • RAB5A
  • Protein-coding gene in the species Homo sapiens

    Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H (Jul 1998). "EEA1 links PI(3)K function to Rab5 regulation of endosome fusion". Nature. 394

    RAB5A

    RAB5A

    RAB5A

  • ESCRT
  • Protein pathway in cells

    four proteins in which it was initially identified: Fab1p, YOTB, Vac1, and EEA1) is found sandwiched between the VHS and ubiquitin interacting motif domains

    ESCRT

    ESCRT

  • Robert D. Burgoyne
  • British physiologist and neuroscientist

    ; McBride, H. M.; Burgoyne, R. D.; Zerial, M. (1999). "The Rab5 effector EEA1 is a core component of endosome docking". Nature. 397 (6720): 621–625. doi:10

    Robert D. Burgoyne

    Robert D. Burgoyne

    Robert_D._Burgoyne

  • APPL1
  • Protein-coding gene in the species Homo sapiens

    endosomes which are negative for EEA1, indicating that APPL1 affects the earliest stages of endosomal traffic before EEA1 takes over. This is in line with

    APPL1

    APPL1

    APPL1

  • FGD1
  • Protein-coding gene in the species Homo sapiens

    domain (named after the four proteins it was found in Fab1, YOTB, Vac1, and EEA1) between residues 730 – 790, and a second PH domain between residues 821

    FGD1

    FGD1

    FGD1

  • RAB5B
  • Protein-coding gene in the species Homo sapiens

    Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H (1999). "Direct interaction of EEA1 with Rab5b". Eur. J. Biochem. 265 (1): 361–6. doi:10.1046/j.1432-1327.1999

    RAB5B

    RAB5B

    RAB5B

  • List of human protein-coding genes 3
  • HGNC:3179; P25101 4723 EDNRB HGNC:3180; P24530 4724 EDRF1 HGNC:24640; Q3B7T1 4725 EEA1 HGNC:3185; Q15075 4726 EED HGNC:3188; O75530 4727 EEF1A1 HGNC:3189; P68104

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • RAB22A
  • Protein-coding gene in the species Homo sapiens

    Stenmark H, Olkkonen VM (2002). "The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking". J. Cell Sci. 115 (Pt 5): 899–911

    RAB22A

    RAB22A

    RAB22A

  • Homeostatic plasticity
  • Capacity of neurons to regulate their own excitability relative to network activity

    ISSN 1662-5099. PMC 5532393. PMID 28804447. Xu X, Pozzo-Miller L (2017-08-15). "EEA1 restores homeostatic synaptic plasticity in hippocampal neurons from Rett

    Homeostatic plasticity

    Homeostatic plasticity

    Homeostatic_plasticity

  • SNX8
  • Protein

    SNX2, Vps26 and Vps35 has been demonstrated by some studies (and also with EEA1). Furthermore, the dynamics of endosomal structures with SNX8-enriched membrane

    SNX8

    SNX8

    SNX8

  • Valosin-containing protein
  • Protein-coding gene in the species Homo sapiens

    PMID 21118995. Ramanathan HN, Ye Y (February 2012). "The p97 ATPase associates with EEA1 to regulate the size of early endosomes". Cell Research. 22 (2): 346–359

    Valosin-containing protein

    Valosin-containing protein

    Valosin-containing_protein

  • RUFY2
  • Protein-coding gene in humans

    initiation factor in bacteria. FYVE domain consists of Fab-1, YGL023, Vps27, and EEA1 proteins. Within the FYVE domain there are Zinc finger binding sites that

    RUFY2

    RUFY2

    RUFY2

  • STX12
  • Protein-coding gene in the species Homo sapiens

    Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13". Cell. 98 (3): 377–86. doi:10.1016/S0092-8674(00)81966-2

    STX12

    STX12

    STX12

  • STX6
  • Protein-coding gene in the species Homo sapiens

    Christoforidis S, Gaullier JM, Brech A, Callaghan J, et al. (July 1998). "EEA1 links PI(3)K function to Rab5 regulation of endosome fusion". Nature. 394

    STX6

    STX6

    STX6

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Online names & meanings

  • Polydorus
  • Boy/Male

    Greek Latin

    Polydorus

    Son of Priam.

  • Lillith
  • Girl/Female

    Arabic, Australian, Danish, Swedish

    Lillith

    Night Owl

  • Jaanakeeraman
  • Boy/Male

    Hindu, Indian, Traditional

    Jaanakeeraman

    Husband of Janaki

  • Ashur
  • Boy/Male

    African, Australian, Christian, Swahili

    Ashur

    Born During Islamic Month Ashur

  • Oswaldo
  • Boy/Male

    American, British, Chinese, English, German, Teutonic

    Oswaldo

    Divine Power

  • Shivalik
  • Boy/Male

    Hindu

    Shivalik

    Belonging of Lord Shiv, Whose owner is Lord Shiv, Lord Shiv in female form. Goddess Parvati

  • Iba
  • Girl/Female

    Indian

    Iba

    Pride, Sense

  • Avyakta
  • Boy/Male

    Indian, Sanskrit

    Avyakta

    Invisible; Nonmanifested

  • Gisele
  • Girl/Female

    Indian

    Gisele

    Pledge

  • Aagni
  • Girl/Female

    Bengali, Indian, Kannada, Marathi

    Aagni

    Fire

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EEA1

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