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ECT2

  • ECT2
  • Gene of the species Homo sapiens

    Protein ECT2 is a protein that in humans is encoded by the ECT2 gene. The protein encoded by this gene is a transforming protein that is related to Rho-specific

    ECT2

    ECT2

    ECT2

  • Classe préparatoire aux grandes écoles
  • French undergraduate education prior to entering grandes écoles

    The Classes préparatoires aux grandes écoles (French pronunciation: [klas pʁepaʁatwaʁ o ɡʁɑ̃dz‿ekɔl], Higher school preparatory classes, abbr. CPGE), commonly

    Classe préparatoire aux grandes écoles

    Classe préparatoire aux grandes écoles

    Classe_préparatoire_aux_grandes_écoles

  • ANLN
  • Mammalian protein found in Homo sapiens

    regions. Anillin interacts with Ect2, further supporting the idea that anillin stabilizes RhoA localization since Ect2 is an activator of RhoA. Independent

    ANLN

    ANLN

    ANLN

  • Montrose Environmental Group
  • American multinational environmental company

    to grow and prosper for many years to come." By 2020, Montrose subsidiary ECT2's water filtration and PFAS removal vessels had been deployed to more than

    Montrose Environmental Group

    Montrose_Environmental_Group

  • Centralspindlin
  • recruits ECT2 to the central spindle. ECT2 is a Guanine nucleotide-exchange factor for RhoA. Cytokinesis is initiated when RhoA is activated by ECT2. RacGAP1

    Centralspindlin

    Centralspindlin

  • Mitosis
  • Cell division into two identical cells

    contraction, both of which are governed upstream by signaling pathways RhoA and ECT2 through the activity of Cdk1. Due to its importance in mitosis, the molecular

    Mitosis

    Mitosis

    Mitosis

  • Cell cortex
  • Layer on the inner face of a cell membrane

    mitosis is regulated by diverse genes such as Rhoa, WDR1, ERM proteins, Ect2, Pbl, Cdc42, aPKC, Par6, DJ-1 and FAM134A. In cytokinesis the cell cortex

    Cell cortex

    Cell cortex

    Cell_cortex

  • RACGAP1
  • Protein-coding gene in the species Homo sapiens

    CRISPR/Cas9 leads to cytokinesis failure. RACGAP1 has been shown to interact with ECT2, Rnd2 and SLC26A8. During cytokinesis, RACGAP1 has been shown to interact

    RACGAP1

    RACGAP1

    RACGAP1

  • Cytokinesis
  • Final stage of cell division

    initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle". Dev. Cell. 12 (5): 713–25. doi:10.1016/j.devcel

    Cytokinesis

    Cytokinesis

    Cytokinesis

  • RhoG
  • Protein-coding gene in the species Homo sapiens

    trans-endothelial migration). Other GEFs reported to interact with RhoG include Dbs, ECT2, VAV2 and VAV3. There have been very few interactions reported between RhoG

    RhoG

    RhoG

    RhoG

  • PARD6A
  • Protein-coding gene in the species Homo sapiens

    upregulate EMT in melanoma. PARD6A has been shown to interact with: CDC42, ECT2 Protein kinase Mζ, and RAC1. Protein kinase C-ι. GRCh38: Ensembl release

    PARD6A

    PARD6A

    PARD6A

  • List of human protein-coding genes 3
  • Q9H1Z8 4701 ECSCR HGNC:35454; Q19T08 4702 ECSIT HGNC:29548; Q9BQ95 4703 ECT2 HGNC:3155; Q9H8V3 4704 ECT2L HGNC:21118; Q008S8 4705 EDA HGNC:3157; Q92838

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • RhoGEF domain
  • Protein domain

    ARHGEF40; ARHGEF5; ARHGEF6/alpha-PIX; ARHGEF7/beta-PIX; ARHGEF9; BCR; DNMBP; ECT2; ECT2L; FARP1; FARP2; FGD1; FGD2; FGD3; FGD4; FGD5; FGD6; ITSN1/Intersectin

    RhoGEF domain

    RhoGEF domain

    RhoGEF_domain

  • YTH protein domain
  • Protein domain

    that two novel Arabidopsis thaliana (Mouse-ear cress) proteins, (ECT1 and ECT2), specifically associated with Calcineurin B-Like-Interacting Protein Kinase1

    YTH protein domain

    YTH_protein_domain

  • Protein kinase C zeta type
  • Mammalian protein found in Homo sapiens

    Liu XF, Ishida H, Raziuddin R, Miki T (2004). "Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • Mitotic cell rounding
  • Shape change in animal cells

    Guck, Jochen; Kunda, Patricia; Baum, Buzz (14 August 2012). "Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression"

    Mitotic cell rounding

    Mitotic_cell_rounding

  • BRCT domain
  • Protein domain

    proteins containing this domain include: BARD1; BRCA1 CTDP1; TDT or DNTT ECT2 LIG4 MCPH1; MDC1 NBN PARP1; PARP4; PAXIP1; PES1 REV1; RFC1; TOPBP1; TP53BP1;

    BRCT domain

    BRCT domain

    BRCT_domain

  • Polo-like kinase
  • allowing the recruitment of the Rho guanine nucleotide-exchange factor (GEF) ECT2 to promote RhoA activation and thus actomyosin contraction of the ring. PLK1

    Polo-like kinase

    Polo-like_kinase

  • PARD3
  • Protein-coding gene in the species Homo sapiens

    Liu XF, Ishida H, Raziuddin R, Miki T (2004). "Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta

    PARD3

    PARD3

    PARD3

  • DEPDC1B
  • Protein-coding gene in the species Homo sapiens

    experimentation have been verified. Medium coexpression of DEPDC1B with ECT2 in cell cycle regulation and DNA synthesis was verified by similarity of

    DEPDC1B

    DEPDC1B

    DEPDC1B

  • Jennifer Rohn
  • American biologist and writer

    Delabre, U.; Rohn, J. L.; Guck, J.; Kunda, P.; Baum, B. (2012). "Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression"

    Jennifer Rohn

    Jennifer Rohn

    Jennifer_Rohn

  • PLK4
  • Protein-coding gene in the species Homo sapiens

    tumors of the brain. Documented PLK4 substrates include STIL, GCP6, Hand1, Ect2, FBXW5, and itself (via autophosphorylation). Autophosphorylation of PLK4

    PLK4

    PLK4

    PLK4

  • Keratin 4
  • Protein found in humans

    Pellman D (ed.). "Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation". PLOS Biol. 7 (5) e1000110

    Keratin 4

    Keratin 4

    Keratin_4

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Online names & meanings

  • Pradhunay
  • Boy/Male

    Indian, Telugu

    Pradhunay

    Very Brave

  • Cheyne
  • Boy/Male

    Australian, Celtic, French

    Cheyne

    God is Gracious; Oak-hearted; Form of Shane

  • Asvathama
  • Boy/Male

    Hindu, Indian

    Asvathama

    Sun of Drona

  • Leenata | லீநதா 
  • Girl/Female

    Tamil

    Leenata | லீநதா 

    Humility

  • Ameila
  • Girl/Female

    British, English, Latin

    Ameila

    Work of the Lord; Hard Working

  • OSVALD
  • Male

    Danish

    OSVALD

    , divine power.

  • Seir
  • Girl/Female

    Australian, Biblical

    Seir

    Hairy; Goat; Demon

  • KHAFS-NOFRU
  • Male

    Egyptian

    KHAFS-NOFRU

    , the son of King Snefru.

  • SIaibhin
  • Boy/Male

    Gaelic

    SIaibhin

    Mountain.

  • Denman
  • Surname or Lastname

    English

    Denman

    English : topographic name for someone who dwelt in a valley (see Dean 1).

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ECT2

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