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Corticosteroid precursor and metabolite of cortisol
Cortisone is a naturally occurring, mostly inactive pregnene (21-carbon) steroid hormone. In the body, cortisone is produced as part of the cortisol–cortisone
Cortisone
Class of steroid hormones
21H 30O 5), corticosterone (C 21H 30O 4), cortisone (C 21H 28O 5) and aldosterone (C 21H 28O 5) (cortisone and aldosterone are isomers). The main corticosteroids
Corticosteroid
Steroid medication
synthetic pregnane corticosteroid and derivative of cortisone and is also known as δ1-cortisone or 1,2-dehydrocortisone or as 17α,21-dihydroxypregna-1
Prednisone
Chemical compound
Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid
Cortisone_acetate
1956 film
schoolteacher and family man whose life spins out of control when he misuses cortisone. It is based on a 1955 article by medical writer Berton Roueché in The
Bigger_Than_Life
American research chemist (1899–1975)
work laid the foundation for the steroid drug industry's production of cortisone, other corticosteroids, and artificial hormones that led to birth control
Percy_Lavon_Julian
Medical condition
Cortisone reductase deficiency is caused by dysregulation of the 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1), otherwise known as cortisone
Cortisone reductase deficiency
Cortisone_reductase_deficiency
Class of enzymes
In enzymology, a cortisone alpha-reductase (EC 1.3.1.4) is an enzyme that catalyzes the chemical reaction 4,5alpha-dihydrocortisone + NADP+ ⇌ {\displaystyle
Cortisone_alpha-reductase
A pregnene is an alkene derivative of a pregnane. An example is cortisone. Cortisone Ethisterone Spironolactone Pregnenes at the U.S. National Library
Pregnene
Class of enzymes
androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase
5β-Reductase
American organic chemist (1899–1977)
as antimalarial drugs, work with steroids leading to the synthesis of cortisone, and study of the nature of polycyclic aromatic hydrocarbons. He also
Louis_Fieser
the 1975 Tour de France by using cortisone. In 1982, after retiring from racing, he said "I was doped with cortisone for three years and there were many
List of doping cases in cycling
List_of_doping_cases_in_cycling
Vertebrate natural glucocorticoid hormone
P450SCC (side-chain cleavage enzyme). Cortisol is metabolized reversibly to cortisone by the 11-beta hydroxysteroid dehydrogenase system (11-beta HSD), which
Cortisol
American cyclist (born 1971)
Armstrong's former soigneur Emma O'Reilly that a backdated prescription for cortisone had been produced in 1999 to avoid a positive test. A 1999 urine sample
Lance_Armstrong
American pharmaceutical manufacturing firm (1886–1995)
the plank. Upjohn developed a process for the large scale production of cortisone. The oxygen atom group must be in position 11 for this steroid to function
Upjohn
American physician (1896–1965)
Prize for Physiology or Medicine in 1950 for the discovery of the hormone cortisone, and its application for the treatment of rheumatoid arthritis. The Nobel
Philip_Showalter_Hench
Medical condition
lesions sometimes cause itching, which can be treated by applying cortisone cream. The cortisone cream will only help with the itching and does not improve the
Schamberg_disease
Class of enzymes
11β-HSD) enzymes catalyze the conversion of inert 11 keto-products (e.g. cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids
11β-Hydroxysteroid dehydrogenase
11β-Hydroxysteroid_dehydrogenase
Mammalian protein found in humans
11β-Hydroxysteroid dehydrogenase type 1, also known as cortisone reductase, is an NADPH-dependent enzyme highly expressed in key metabolic tissues including
11β-Hydroxysteroid dehydrogenase type 1
11β-Hydroxysteroid_dehydrogenase_type_1
Danish cyclist (born 1964)
Tinkov. On 25 May 2007, Riis admitted he had used EPO, growth hormone and cortisone between 1993 and 1998, including during his Tour de France victory. The
Bjarne_Riis
Chemical compound
of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. It is present
Diosgenin
Mineralocorticoid medication
synthetic corticosteroid to be marketed, and followed the introduction of cortisone in 1948 and hydrocortisone (cortisol) in 1951. Fludrocortisone was also
Fludrocortisone
Chemical compound
20-trione, is a naturally occurring, endogenous corticosteroid related to cortisone and corticosterone. It is a potent mineralocorticoid, with generally greater
11-Dehydrocorticosterone
American child actress (1975–1988)
subsequently diagnosed as having Crohn's disease. She was prescribed cortisone injections to treat the disease during the time she was filming Poltergeist
Heather_O'Rourke
Genus of fungi
Sweet potato and is used in commercial production of fumaric acid and cortisone. Various species, including R. stolonifer, may cause soft rot in sweet
Rhizopus
Corticosteroid medication
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Prednisolone
Medical treatment for adhesive capsulitis of shoulder
assisted by a radiographer. Contrast medium, a local anaesthetic and cortisone are injected into the joint. Then up to 40ml of sterile saline solution
Hydrodilatation
Chemical compound
21-trihydroxy-5β-pregnane-11,20-dione, is a steroid and an inactive metabolite of cortisone. Tetrahydrocortisol Tetrahydrocorticosterone Thomas L. Lemke; David A
Tetrahydrocortisone
Pharmaceutical drug
activity of 7.5 mg of deflazacort is approximately equivalent to 25 mg cortisone, 20 mg hydrocortisone, 5 mg of prednisolone or prednisone, 4 mg of methylprednisolone
Deflazacort
Endocrine gland
blood pressure and electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation
Adrenal_gland
Chemical compound
steroid formed from cortisone by the 5β-reductase enzyme, which uses nicotinamide adenine dinucleotide phosphate as its cofactor. cortisone + NADPH H+
Dihydrocortisone
American academic medical center
people awarded the Nobel Prize in medicine in 1950 for the discovery of cortisone. Professor Edward C. Kendall, Ph.D., and Philip S. Hench of Mayo Clinic
Mayo_Clinic
the isolation and characterisation of vitamin D, and the synthesis of cortisone from naturally occurring steroids. After he retired from the NIMR in 1966
Kenneth_Callow
Pharmaceutical compound
Chlorophenylsilatrane Cicutoxin Cloflubicyne Cortisol (hydrocortisone) Cortisone Cyclothiazide DHEA DHEA-S Dieldrin (+)-DMBB DMCM DMPC EBOB Etbicyphat
INDV-1000
Hormone-producing glands of a body
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Endocrine_system
Pharmaceutical compound
Chlorophenylsilatrane Cicutoxin Cloflubicyne Cortisol (hydrocortisone) Cortisone Cyclothiazide DHEA DHEA-S Dieldrin (+)-DMBB DMCM DMPC EBOB Etbicyphat
Orenetide
Index of articles associated with the same name
Fenistil Cold Sore Cream, containing penciclovir FeniHydrocort, containing cortisone This set index article includes a list of related items that share the
Fenistil
American actor (1957–2020)
its effects in an interview: "At first it distorted my hands. Then the cortisone I had to take made my cheeks fat. At 8, I lost movement in my neck. When
Clark_Middleton
Death of bone tissue due to interruption of the blood supply
substances. During that tour, Landis was allowed cortisone shots to help manage his ailment despite cortisone also being a banned substance in professional
Avascular_necrosis
Mineralocorticoid steroid hormone
with intracellular adrenal steroid receptors and converts cortisol into cortisone, a relatively inactive metabolite with little affinity for the MR. Liquorice
Aldosterone
Short chains of 2–50 amino acids
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Peptide
Puerto Rican baseball player (born 1977)
revealed that the elbow had a bone spur, and he was immediately given a cortisone shot. He was placed on the 15-day disabled list on May 15, 2014. He was
Carlos_Beltrán
Medical condition
walking. Treatment in humans consists of anti-inflammatory medication, cortisone injections, strapping to immobilize the big toe, and orthotics with special
Sesamoiditis
American organic chemist (1917–1999)
serving as a research scientist at Merck & Co., Inc., he synthesized cortisone. He was born in Champaign, Illinois. His father was Lew Sarett, a renowned
Lewis_Hastings_Sarett
American baseball player and politician (born 1980)
aggravated the wrist on June 15, 2013, and the next day, he received cortisone injections to treat the inflammation of the wrist. He was again placed
Mark_Teixeira
Index of chemical compounds with the same molecular formula
mass: 360.44 g/mol, exact mass: 360.193674 u) may refer to: Aldosterone Cortisone Prednisolone, a corticosteroid Roxibolone, an anabolic steroid This set
C21H28O5
Factor that stimulates the growth of bone tissue
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Bone_growth_factor
American bass singer (1942–1995)
symptoms of which he combated with cortisone so that he could continue performing. The constant use of cortisone left his immune system vulnerable to
Melvin_Franklin
Covalent bond between two carbon atoms
quaternary loci are found in many biologically active small molecules, such as cortisone and morphine. Carbon–carbon bond-forming reactions are organic reactions
Carbon–carbon_bond
Polish-Swiss chemist (1897–1996)
Medicine laureate (1950), which was awarded for his work on the isolation of cortisone. Reichstein was born into a wealthy Polish-Jewish family with strong Polish
Tadeusz_Reichstein
Danish cyclist
EPO, growth hormones, insulin, testosterone, DHEA, IGF-1, Oxyglobin, cortisone and blood doping, for most of his professional career. Rasmussen began
Michael_Rasmussen_(cyclist)
American basketball player and analyst (born 1972)
19–3 in games that O'Neal played over 20 minutes. After requesting a cortisone shot, O'Neal returned April 3 after missing 27 games due to his Achilles;
Shaquille_O'Neal
Medical condition
isozyme inactivates circulating cortisol to the less active metabolite cortisone. Liquorice consumption can also inhibit the enzyme and cause AME. The
Apparent mineralocorticoid excess syndrome
Apparent_mineralocorticoid_excess_syndrome
Ability of a solid material to exist in more than one form or crystal structure
second polymorph was found with more suitable compressive properties. Cortisone acetate exists in at least five different polymorphs, four of which are
Crystal_polymorphism
Synthetic route in steroid chemistry
chemist Russell Earl Marker in 1938–1940. It is used for the production of cortisone and mammalian sex hormones (progesterone, estradiol, etc.) from plant
Marker_degradation
Disorder of pain and tenderness in the sinus tarsi
such as physical and orthotic therapy, and more invasive ones such as cortisone injections. The condition is somewhat poorly understood and is subject
Sinus_tarsi_syndrome
Medication for skin
to all steroids in that group. Hydrocortisone, hydrocortisone acetate, cortisone acetate, tixocortol pivalate, prednisolone, methylprednisolone, and prednisone
Topical_steroid
American chemist (1906–1989)
he led the research teams that synthesized ascorbic acid, riboflavin, cortisone, pyridoxine, pantothenic acid, nicotinamide, methionine, threonine, and
Max_Tishler
Medical condition featuring permanent bending of fingers
fibroblastic and myofibroblastic tumors. Initial treatment is typically with cortisone injected into the affected area, occupational therapy, and physical therapy
Dupuytren's_contracture
Medical condition
ability of 11-β-HSD2 to transform active cortisol to the less active cortisone. Excess cortisol is then able to bind and activate mineralocorticoid receptors
Pseudohyperaldosteronism
Corticosteroid medication
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Methylprednisolone
Species of shrub
was a natural source of the steroid hormone cortisone and was used in the early manufacture of cortisone-based drugs. Horn-like, paired, follicular fruits
Strophanthus_sarmentosus
Irish sports journalist
Hospital on 27 October 1996 that you had taken EPO, human growth hormone, cortisone, steroids and testosterone?. This question was the first of 10 questions
David_Walsh_(journalist)
Steroid medication
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Triamcinolone
American politician and lawyer (1925–1968)
that John had Addison's disease, saying that he required life-sustaining cortisone treatments. Though in fact a diagnosis had been made, Robert tried to
Robert_F._Kennedy
Greek business magnate (1906–1975)
the previous month. The pneumonia was particularly exacerbated by the cortisone he was taking for his myasthenia gravis from which he had suffered in
Aristotle_Onassis
Chemical compound
11-Ketoprogesterone 21-Deoxycortisol 21-Deoxycortisone Corticosterone Cortisol Cortisone 17α-Hydroxypregnenolone 17α-Hydroxyprogesterone Pregnenolone Progesterone
5α-Pregnan-17α-ol-3,20-dione
Skin condition
salicylic acid. In order to reduce inflammation, creams and salves containing cortisone are often very effective.[citation needed] Topical corticosteroids are
Hand_eczema
Chemical compound
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Methylprednisolone_aceponate
Chinese pulmonologist
take in and alleviated pain. Zhong also insisted on proposing the use of cortisone for the treating of patients experiencing severe conditions, which significantly
Zhong_Nanshan
Chemical compound
Hydrocortamate (hydrocortisone diethylaminoacetate) Hydrocortisone esters Cortisone Cortisone acetate Deprodone Deprodone propionate Dichlorisone Dichlorisone
Metribolone
Type of corticosteroid medication
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Budesonide
Species of spider with venomous bite native to US
depending on pain scores, an anti-inflammatory agent (e.g. naproxen, cortisone), and an antispasmodic (e.g. cyclobenzaprine, diazepam), for a few days
Brown_recluse_spider
Chemical compound
Hydrocortamate (hydrocortisone diethylaminoacetate) Hydrocortisone esters Cortisone Cortisone acetate Deprodone Deprodone propionate Dichlorisone Dichlorisone
Prednisolone_sodium_phosphate
Hormone of the gastrointestinal system
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Cholecystokinin
Steroid medication
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Betamethasone
French painter (1877–1953)
In April he went to Boston to undergo an experimental treatment with cortisone and corticotropin, based on the work of Philip S. Hench. It proved successful
Raoul_Dufy
Steroidal progestin drug
2010-07-08. Lenco W, Mcknight M, Macdonald AS (January 1975). "Effects of cortisone acetate, methylprednisolone and medroxyprogesterone on wound contracture
Medroxyprogesterone
Form of scarring
skin. This is especially true when there is an increase in cortisone – an increase in cortisone levels can increase the probability or severity of stretch
Stretch_marks
Proteins similar to insulin that stimulate cell proliferation
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Insulin-like_growth_factor
One of four stable isomers of butanediol
Chlorophenylsilatrane Cicutoxin Cloflubicyne Cortisol (hydrocortisone) Cortisone Cyclothiazide DHEA DHEA-S Dieldrin (+)-DMBB DMCM DMPC EBOB Etbicyphat
1,4-Butanediol
English filmmaker (1899–1980)
was too ill to travel to London—he had a pacemaker and was being given cortisone injections for his arthritis—so on 3 January 1980 the British consul general
Alfred_Hitchcock
Substance with biological function
Glucocorticoids: alclometasone, prednisone, dexamethasone, triamcinolone, cortisone Mineralocorticoid: fludrocortisone Vitamin D: dihydrotachysterol Androgens:
Steroid_hormone
American weightlifter (born 1989)
London to compete, Mangold tore a tendon in her wrist and required three cortisone shots before the super heavyweight competition. Mangold placed tenth out
Holley_Mangold
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Gonadotropin surge-attenuating factor
Gonadotropin_surge-attenuating_factor
Use of illegal substances by cyclists in the Tour de France
won the 1975 and 1977 Tour de France editions by using cortisone. "I was doped with cortisone for three years and there were many like me", he said. The
Doping_at_the_Tour_de_France
Pharmaceutical drug classification
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
ATC_code_D07
Thickening of the feet's deep connective tissue (fascia)
success rate and potentially lower recurrence than conventional surgery. Cortisone injections, such as triamcinolone, and clobetasol ointments have been
Plantar_fibromatosis
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Relaxin-3
Chemical compound
Glucocorticoids and antiglucocorticoids (D07, H02) Glucocorticoids Natural Cortisone Cortisone acetate Cortodoxone (cortexolone, 11-deoxycortisol) Desoxycortone
Methylprednisolone_acetate
Thyroid hormone
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Thyroxine
Oily mixture of plant compounds
and itching. Once this response starts, only a few treatments, such as cortisone or prednisone, are effective. Medications that can reduce the irritation
Urushiol
American chemist (1917–1979)
synthesized many complex natural products including quinine, cholesterol, cortisone, strychnine, lysergic acid, reserpine, chlorophyll, cephalosporin, and
Robert_Burns_Woodward
Former tuberculosis sanatorium and hospital in Selah, Washington
testing the effectiveness of cortisone as one of the treatments of tuberculosis under the direction of Dr. Allen. While cortisone was unable to stop the disease
Central Washington Tuberculosis Hospital
Central_Washington_Tuberculosis_Hospital
11-Ketoprogesterone 21-Deoxycortisol 21-Deoxycortisone Corticosterone Cortisol Cortisone 17α-Hydroxypregnenolone 17α-Hydroxyprogesterone Pregnenolone Progesterone
List_of_neurosteroids
American guitarist (born 1957)
did not actually have carpal tunnel syndrome, and he was now receiving cortisone shots because he no longer had any cartilage remaining in his right hand
Jake_E._Lee
American baseball player (born 1972)
right knee for much of the first half of the 2011 season and received Cortisone shots in an attempt to manage the pain. When this became ineffective,
Chipper_Jones
Mammalian protein found in Homo sapiens
Endorphins Lipotropin GH Adrenal axis Adrenal cortex Aldosterone Cortisol Cortisone DHEA DHEA-S Androstenedione Adrenal medulla Adrenaline Norepinephrine
Growth hormone–releasing hormone
Growth_hormone–releasing_hormone
Chemical compound
11-Ketoprogesterone 21-Deoxycortisol 21-Deoxycortisone Corticosterone Cortisol Cortisone 17α-Hydroxypregnenolone 17α-Hydroxyprogesterone Pregnenolone Progesterone
17α-Hydroxyprogesterone
American professional baseball executive (born 1954)
2006, Majewski was revealed to have a tired arm, and had received a cortisone shot prior to the trade. He was placed on the 15-day Disabled list and
Wayne_Krivsky
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