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The chaperone code refers to post-translational modifications of molecular chaperones that control protein folding. Whilst the genetic code specifies
Chaperone_code
1998 musical
The Drowsy Chaperone is a Canadian musical with music and lyrics by Lisa Lambert and Greg Morrison, and a book by Bob Martin and Don McKellar. The story
The_Drowsy_Chaperone
2018 film directed by Michael Engler
The Chaperone is a 2018 period drama film, directed by Michael Engler, with a screenplay by Julian Fellowes, from the novel by Laura Moriarty. It stars
The_Chaperone_(2018_film)
1st episode of the 6th season of Seinfeld
"The Chaperone" is the first episode of the sixth season of the American television sitcom Seinfeld, and the 87th episode overall. It first aired on NBC
The_Chaperone_(Seinfeld)
Canadian scientist
methylation of molecular chaperones is a central element of a posttranslational modification code, they termed the "chaperone code", that orchestrates the
Benoit_Coulombe
British-American biochemist (born 1973)
(2020-08-07). "Post-translational modifications of Hsp90 and translating the chaperone code". The Journal of Biological Chemistry. 295 (32): 11099–11117. doi:10
Mehdi_Mollapour
DNA mutation with no observable effect on an organism's phenotype
genetic code". Nucleic Acids Research. 34 (8): 2428–37. doi:10.1093/nar/gkl287. PMC 1458515. PMID 16682450. Herschlag D (September 1995). "RNA chaperones and
Silent_mutation
Chemical compound
BPPSA (N‐(2‐bromophenyl)pyrrolidine‐1‐sulfonamide) is a small molecular chaperone that helps partially stabilize the P187S variant of NQO1, recovering part
BPPSA
American and French actor (born 1995)
Holden, Stephen (September 15, 2016). "Review: In 'Miss Stevens,' a Chaperone Greets Temptation". The New York Times. Archived from the original on
Timothée_Chalamet
Protein-coding gene in the species Homo sapiens
chromosome 11. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded
HSPA8
Corticosteroid medication
Upon binding, the formation of the GC/GCR complex causes dissociation of chaperone proteins from the glucocorticoid receptor enabling the GC/GCR complex
Prednisolone
American actor
Meanie (2025) as The Chaperone Appofeniacs (2025) as Cedrick Night Patrol (2025) as Xavier Carr Faces of Death (2026) as Josh Guy Code (2012) as Himself
Jermaine_Fowler
Heat shock proteins with a molecular mass around 90kDa
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in
Hsp90
Family of proteins
wound healing or tissue remodeling. Many members of this group perform chaperone functions by stabilizing new proteins to ensure correct folding or by
Heat_shock_protein
Protein-coding gene in the species Homo sapiens
Tubulin-specific chaperone E is a protein that in humans is encoded by the TBCE gene. Cofactor E is one of four proteins (cofactors A, D, E, and C) involved
TBCE
Chemical compound
Sodium phenylbutyrate is also a histone deacetylase inhibitor and chemical chaperone, leading respectively to research into its use as an anti-cancer agent
Sodium_phenylbutyrate
Corticosteroid medication
multiprotein complexes with heat shock proteins (HSPs), immunophilins, and other chaperones such as src, and p23. The GR acts in a ligand-dependent manner, with the
Methylprednisolone
know what he's doing. Margaret tells Jim that they've been asked to be chaperones at the dance. Jim doesn't want Bud to be surprised when his parents are
List of Father Knows Best episodes
List_of_Father_Knows_Best_episodes
Free online crowdsourced encyclopedia
December 26, 2008. Wilson, Chris (February 22, 2008). "The Wisdom of the Chaperones". Slate. Archived from the original on September 5, 2011. Retrieved August
Wikipedia
Protein-coding gene in the species Homo sapiens
encoded by this gene binds to and inhibits the ATPase activity of the chaperone proteins HSC70 and HSP70 and blocks the forward reaction of the HSC70-HSP70
STUB1
Medication for transthyretin amyloidosis
drugs that rely on those transporters. Tafamidis is a pharmacological chaperone that stabilizes the correctly folded tetrameric form of the transthyretin
Tafamidis
2nd episode of the 6th season of Seinfeld
Hallo as Gendason Lauren Bowles as Waitress Episode chronology ← Previous "The Chaperone" Next → "The Pledge Drive" Seinfeld season 6 List of episodes
The_Big_Salad
Protein found in humans
BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy
BAG3
22nd episode of the 5th season of Seinfeld
Player #3 Jeffrey von Meyer as Poker Player #4 Episode chronology ← Previous "The Hamptons" Next → "The Chaperone" Seinfeld season 5 List of episodes
The_Opposite
1946 fire in Atlanta, Georgia
staying at the Winecoff. She suffocated with another delegate and their chaperone in room 926. Christine Adams Hinson (age 17), daughter of Isham Lamar
Winecoff_Hotel_fire
American science fiction TV series
Karolina Wydra as Zosia, a Polish member of the Others who acts as Carol's chaperone Carlos-Manuel Vesga as Manousos Oviedo, a Colombian immune individual
Pluribus_(TV_series)
Pharmaceutical compound
proteins in the ON state. To inhibit RAS, daraxonrasib first binds a chaperone molecule (cyclophilin A), which results in a complementary surface. This
Daraxonrasib
Chris's deal worked out. Ziggy runs into Fatty who asks her to consider chaperoning one of his young stars so she feigns sickness to be Fatty's assistant
List_of_Traders_episodes
curmudgeonly history teacher at a New England prep school is forced to chaperone the handful of students with nowhere to go over Christmas break. Holidate
List_of_Christmas_films
Protein-coding gene in the species Homo sapiens
functions as a co-chaperone which reversibly links together the chaperone proteins Hsp70 and Hsp90. STI1 belongs to the large group of co-chaperones, which regulate
Stress-induced-phosphoprotein 1
Stress-induced-phosphoprotein_1
Protein-coding gene in the species Homo sapiens
Tubulin-specific chaperone D is a protein that in humans is encoded by the TBCD gene. Cofactor D is one of four proteins (cofactors A, D, E, and C) involved
TBCD
Chemical compound
and PARP-dependent energy crisis in human skin cells". Cell Stress & Chaperones. 15 (3): 309–322. doi:10.1007/s12192-009-0145-6. PMC 2866994. PMID 19809895
Zinc_pyrithione
Process of cells digesting parts of themselves
forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. In macroautophagy (the most
Autophagy
Chemical compound
on their binding properties to prion proteins: implications as medical chaperones". Protein Science. 22 (1): 22–34. doi:10.1002/pro.2180. PMC 3575857. PMID 23081827
Pentosan_polysulfate
the valley trying to get support for the festival. Meanwhile, Doris is chaperoning Arnold and his girlfriend Sue Ann. Lisa comes by to talk about the festival
List_of_Green_Acres_episodes
American sitcom
lies to Leanne and Carol about going to the doctor's. Leanne decides to chaperone Daddy to all his doctor's appointments and coordinates all his appointments
Leanne_(TV_series)
American comedy series
punishment for leaving his classes early for rehearsals, Kate forces Kel to chaperone the winter formal. He recruits Abby to help Beth, a snobby student who
Not_Suitable_for_Work
Dad [de] Mark von Seydlitz [de] Julia Stinshoff, Lambert Hamel Comedy a.k.a. Chaperoned a.k.a. Urlaub mit Papa Der verlorene Sohn [de] Nina Grosse Katja Flint
List of German films of the 2000s
List_of_German_films_of_the_2000s
Protein-coding gene in humans
is protease resistant and is responsible for the oligomerization and chaperone activity of these proteins. It contains several hydrophobic residues that
Nucleophosmin
Medication
strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase
Miglustat
American actress
operative Liz "Foxfire" Towne, in the short-lived NBC action television series Code Name: Foxfire (1985). In 1982, Cassidy had her breakthrough film role as
Joanna_Cassidy
Protein found in humans
was first discovered. This protein was the first identified molecular chaperone. It is a thermostable acidic protein with a pentameric structure and is
Nucleoplasmin-2
Hopewell Paul Rose 11 March 2015 (2015-03-11) N/A After Dexter agrees to chaperone Nero at Elmsmere's parents' evening and assigns the gang more homework
List of 4 O'Clock Club episodes
List_of_4_O'Clock_Club_episodes
Indian actress (1933–1969)
pushed her into anything ... He couldn't imagine he'd get so caught up chaperoning her that he'd never get back to working himself." Madhubala was eventually
Madhubala
American actress (1905–1965)
left New York, her father, and her boyfriend behind for Hollywood. As chaperone for the journey and her subsequent southern California stay, the studio
Clara_Bow
2019 Marvel Studios film
#CaptainMarvelChallenge, a campaign to purchase tickets and refreshments for girls and chaperones at the Greater Los Angeles chapter of Girls, Inc. The campaign, inspired
Captain_Marvel_(film)
Protein-coding gene in the species Homo sapiens
that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly
Binding immunoglobulin protein
Binding_immunoglobulin_protein
Christian sect formerly known as the Exclusive Brethren
marriage and are encouraged to marry within the fellowship. Courtship is chaperoned, and physical intimacy before marriage is strongly discouraged. Elderly
Plymouth Brethren Christian Church
Plymouth_Brethren_Christian_Church
Mexican-American actress (1956)
Episode (1.2) 1984 The Love Boat Samantha Gregory Episode " My Mother, My Chaperone/Present, The/Death and Life of Sir Alfred Demerest, The/Welcome Aboard:
Ana_Alicia
Protein-coding gene in the species Homo sapiens
Mesoderm development LRP chaperone, or MESD, is a protein that in humans is encoded by the MESD gene. GRCh38: Ensembl release 89: ENSG00000117899 – Ensembl
Mesoderm development LRP chaperone
Mesoderm_development_LRP_chaperone
Mammalian protein involved in blood clotting
reference expression data BioGPS n/a Gene ontology Molecular function chaperone binding protein homodimerization activity collagen binding protein N-terminus
Von_Willebrand_factor
American monster television series
to Japan under an alias after discovering that her company was using her code for nefarious purposes. Her real name is later revealed as Corah Mateo. Ren
Monarch:_Legacy_of_Monsters
knowing. Mary also tries to avoid being alone with Pastor Rob while chaperoning the event. George takes Principal Petersen out and runs into Brenda anyway
List of Young Sheldon episodes
List_of_Young_Sheldon_episodes
American businessman (1930–2010)
permit a Yankees uniform to appear on the sixth-season episode, "The Chaperone". The owner was still angry about the unauthorized pennant, and knew so
George_Steinbrenner
Protein-coding gene in the species Homo sapiens
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. The oncogene BCL2 is a membrane protein that blocks
BAG1
Annual period when the social elite holds social events
ladies appeared in white gowns and were accompanied by ever-watchful chaperones. Dancing was confined to quadrilles and waltzes; anything else was considered
Social_season
Topics referred to by the same term
Australian Multicultural Council U.S. Army Chemical Materials Activity Chaperone-mediated autophagy Calcium magnesium acetate, an inorganic compound
CMA
Chaperoned student group on foot
school bus) is a form of student transport for young schoolchildren who, chaperoned typically by two adults (a "driver" leads and a "conductor" follows),
Walking_bus
Period drama television series
added to the cast. Simone Kirby joined the cast in October as the girls' chaperone. In December 2023, it was confirmed that the main ensemble would return
The Buccaneers (2023 TV series)
The_Buccaneers_(2023_TV_series)
Pharmaceutical compound
β-glucocerebrosidase (GCase) activator, positive allosteric modulator, and/or chaperone which is under development for the treatment of Parkinson's disease, Gaucher's
GT-02287
Phylum of microscopic animals
propose (2019) that this may serve "as a RNA-chaperone involved in regulation of translation [of RNA code to proteins] following freezing." Tardigrade
Tardigrade
not to be left in a room alone with him again. According to McDowell, a chaperone had accompanied her to Trump's office. At the time, McDowell was 21 and
Donald Trump sexual misconduct allegations
Donald_Trump_sexual_misconduct_allegations
2012 Microsoft operating system version
16, 2012. Retrieved June 11, 2012. "Windows 8 'Family Safety' feature chaperones underage users through the World Wild Web". Engadget. AOL. May 14, 2012
Windows_8
does not spend much time with his mother, but one day she agrees to help chaperone a field trip with his class. He is thrilled by his mother's involvement
List_of_Mad_Men_characters
Protein-coding gene in humans
Endoplasmic reticulum protein 29 (ERp29) is a chaperone protein that in humans is encoded by the ERP29 gene. ERp29 is a reticuloplasmin, a protein which
ERP29
Protein-coding gene in the species Homo sapiens
GroEL is a protein which belongs to the chaperonin family of molecular chaperones, and is found in many bacteria. It is required for the proper folding
GroEL
British actor (born 1953)
(1991), Boogie Nights (1997), Chocolat (2000), Luther (2003), The Da Vinci Code (2006), and Love Is Strange (2014). He has voiced characters in Rango (2011)
Alfred_Molina
English editor (1868–1905)
carriage with the elderly family cook Elizabeth Harper (or other servant as chaperone) or her fellow illustrator and friend Gertrude Woodward. Potter and Warne
Norman_Warne
Protein-coding gene in humans
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control
CDC37
Protein-coding gene in the species Homo sapiens
Mitochondrial chaperone BCS1 (BCS1L), also known as BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone (h-BCS1), is a protein that in humans
BCS1L
Ethnic group of Louisiana, USA
transported to Louisiana. (The Ursuline order of nuns, who were said to chaperone the girls until they married, denied the casket girl myth.) The system
Louisiana_Creole_people
Major character on the TV show "Seinfeld"
personal assistant to the eccentric, demanding Justin Pitt, starting in "The Chaperone", but later is fired when Mr. Pitt thinks she and Jerry are conspiring
Elaine_Benes
British television soap opera (1985–present)
spent on scripts and £6.9 million went towards paying actors, extras and chaperones for child actors. According to the NAO, BBC executives approved £500,000
EastEnders
"A car hits a school group in the Netherlands, killing 2 kids and a chaperone". AP News. Retrieved 11 June 2026. "Syrian sentenced to 26 years in prison
2026_in_the_Netherlands
He trained under S. Theodora Markson, who was also Lemony Snicket's chaperone during his early training. Markson often describes Bertrand as a model
List of A Series of Unfortunate Events characters
List_of_A_Series_of_Unfortunate_Events_characters
English actress
Kenvale Recruitment. Bettles was born in 1969 to a mother who worked as a chaperone for the Grange Hill series from its inception in 1978 to 2002. She and
Alison_Bettles
Species of Gram-positive bacterium
growth of competitor S. aureus strain in vitro. EsaD is cosecreted with chaperone EsaE, which stabilises EsaD structure and brings EsaD to EssC for secretion
Staphylococcus_aureus
existence of 17 previously undescribed sRNAs, many of which bind to the chaperone protein Hfq and regulate the translation of RpoS (Sigma 38). UptR sRNA
Escherichia_coli_sRNA
Muslim dating app
detailed profile creation, selfie verification, privacy settings, and a chaperone feature that allows a third party to monitor interactions. The app also
Muzz_(dating_app)
English actor and television presenter
tour 2016 A Chorus Line – Zach, 2013 The London Palladium The Drowsy Chaperone – Novello Theatre, 2007 Miss Saigon – John, UK tour 2005 Taboo – Marilyn
John_Partridge_(actor)
hosted by Cheryl. As Lori covers for Lynn Sr. and Rita into being Lola's chaperone due to both of them being unavailable, Lola worries about losing when
List of The Loud House episodes
List_of_The_Loud_House_episodes
Protein-coding gene in the species Homo sapiens
Tubulin-specific chaperone A is a protein that in humans is encoded by the TBCA gene. The product of this gene is one of four proteins (cofactors A, D
TBCA
Protein family around which DNA winds to form nucleosomes
modifications, known as histone marks, are thought to constitute a code, the so-called "histone code". Histone modifications act in diverse biological processes
Histone
1920s women's subculture
Flock and the Royal Order of the Flapper. Flappers shrugged off their chaperones, danced suggestively, and openly flirted with boys. "Flappers prized style
Flapper
Protein-coding gene in the species Homo sapiens
functions as a co-chaperone which inhibits the ATPase activity of the chaperone Hsp90 (heat shock protein-90) and decelerates its chaperone cycle. FNIP1 acts
FNIP1
American series of parties hosted by Sean Combs
it in 2000, lent Combs the Declaration but hired three armed guards to chaperone it throughout the night. This marked "a new level of fortune and braggadocio"
Diddy_parties
2025 American television series
positive compliment towards Phoebe's leadership book. Phoebe ropes Max into chaperoning the field trip. Later that night, Thunderford sends a text to the Thundermans
The_Thundermans:_Undercover
American supernatural horror television series
boys to continue their work on earth, assigning Night Nurse as their chaperone. Somewhere in the Arctic, the Sprites sit with an unknown figure holding
Dead Boy Detectives (TV series)
Dead_Boy_Detectives_(TV_series)
American actor (born 1991)
Year Title Role Notes 2016 The Layoff Jeremy Short film 2018 The Chaperone Floyd Spare Room Matt 2024 The Front Room Norman 2025 Snow White Jonathan TBD
Andrew_Burnap
1996 aviation accident in the Atlantic Ocean
dismissed the previous week. In addition, 16 students and five adult chaperones from the French Club of the Montoursville Area High School in Pennsylvania
TWA_Flight_800
Improvisational comedy podcast
McKenna as Sherry Barrels Zach Reino as Dash Grabum Episode 642: Chicago Chaperone 2/24/20 Jimmy Pardo Niccole Thurman as Crystal Del Rey Jenner Matt Apodaca
Comedy_Bang!_Bang!
German philosopher (1844–1900)
Tautenburg in Thuringia, often with Nietzsche's sister Elisabeth as a chaperone. Salomé reports that he asked her to marry him on three separate occasions
Friedrich_Nietzsche
2026 video game
they will need to go meet up with their half brother Jeppy who is being chaperoned by Creature (Tim Robinson), a gatlian from the first game. When we go
High_on_Life_2
Cystic fibrosis drug
destroy such proteins soon after they are made; lumacaftor acts as a chaperone during protein folding and increases the number of CFTR proteins that
Lumacaftor/ivacaftor
American television sitcom
facilitate a camping field trip. Evan and Gwen are dogged by Sharon, a parent chaperone who is paranoid about the students playing sex games. Evan becomes jealous
English_Teacher_(TV_series)
American animated children's television series
adult red squirrel and is the neighbour of Kip. She usually acts as a chaperone and motherly figure for the kids. She is the only animal in the gang.
Higglytown_Heroes
American comedy-drama television series
in the house and yells at Max and her friends for leaving it out. Sam chaperones Frankie and her friends to a poetry slam event where they are performing;
Better_Things_(TV_series)
American author, journalist, and social activist (1876–1916)
visit with her sister Tess and her chaperone, Miss Hadley. It hardly seems likely that someone who required a chaperone on Saturday would move aboard as
Jack_London
Swiss psychologist (1896–1980)
Burman, J. T. (2008). "Experimenting in relation to Piaget: Education is a chaperoned process of adaptation". Perspectives on Science. 16 (2): 160–195. doi:10
Jean_Piaget
Protein in the mitochondrion mostly expressed in highly metabolic cells
of iron-sulfur clusters. It has been proposed to act as either an iron chaperone or an iron storage protein. Reduced expression of frataxin is the cause
Frataxin
travel, tourism, insurance
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