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Protein-coding gene in the species Homo sapiens
chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy. BAG proteins
BAG3
and HSPB8, and the cochaperones BAG3 and STUB1. The cochaperone BAG3 plays a vital role in maintaining homeostasis. BAG3 facilitates the cooperation of
Chaperone-assisted selective autophagy
Chaperone-assisted_selective_autophagy
Historical peoples in China and Vietnam
Cantonese Yale Romanization Baak yuht Jyutping Baak3 jyut6 Canton Romanization Bag3 yüd6 IPA [pak̚˧ jyt̚˨] Southern Min Hokkien POJ Pah-oa̍t Eastern Min Fuzhou
Baiyue
Unicode character block
005 BA.BA.ZA = "porridge" 𒁁[4] U+12041 BAD 113 69 BA9, MUD2 𒁂 U+12042 BAG3 78 𒁃 U+12043 BAḪAR2 309 𒁄 U+12044 BAL 005 9 𒁅 U+12045 BAL / BAL 𒁆 U+12046
Cuneiform_(Unicode_block)
Aggregation of misfolded proteins in cells
ubiquitin-independent pathway mediated by the stress-induced co-chaperone BAG3 (Bcl-2-associated athanogene 3), which transfers misfolded protein substrates
Aggresome
Protein-coding gene in the species Homo sapiens
(BAG1). HSPA8 has also been shown to interact with: BBC Three, BAG1, BAG2, BAG3, BAG4, CDC5L, CITED1, CCND1, DNAJA3, GJA1, HSPBP1, PARK2, and STUB1. GRCh38:
HSPA8
Family of heat shock proteins
directs ubiquitin-proteasome degradation; BAG3 inhibits NEF, retaining substrate in SBDβ (HSF1 active). BAG3 decrease releases NEF, enabling substrate
Hsp70
Protein-coding gene in the species Homo sapiens
BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian
BAG2
American professor of biology
Kopito Lab. Behl, Christian (1 August 2016). "Breaking BAG: The Co-Chaperone BAG3 in Health and Disease". Trends in Pharmacological Sciences. 37 (8): 672–688
Ron_Kopito
Protein-coding gene in humans
turnover of CapZβ1 is in part regulated by the Bcl-2–associated athanogene, BAG3, through a mechanism involving the association between HSC70 and CapZβ1.
CAPZB
Protein found in humans
targeting intermembrane proteins. PLCG1 has been shown to interact with: BAG3, CD117, CD31, Cbl gene CISH Epidermal growth factor receptor, Eukaryotic
PLCG1
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
Lee HO, et al. (September 2016). "A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism". Molecular
Stress_granule
HGNC:936; Q92934 1404 BAG1 HGNC:937; Q99933 1405 BAG2 HGNC:938; O95816 1406 BAG3 HGNC:939; O95817 1407 BAG4 HGNC:940; O95429 1408 BAG5 HGNC:941; Q9UL15 1409
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Protein-coding gene in the species Homo sapiens
has been shown to have Protein-protein interactions with the following. BAG3 ARF1 CALM1 HNRNPL GRCh38: Ensembl release 89: ENSG00000184381 – Ensembl,
PLA2G6
Human gene
characterized between Hsp70-2 and the following proteins: ATF5, BAG1, BAG2, BAG3, CatSperβ, CDC2, CHCHD3, DNAJC7, DNAJC8, DNAJC9, FOXP3, HDAC4, HOPX, HSP40
HSPA1B
Protein-coding gene in the species Homo sapiens
patients. HSPA1A has been shown to interact with: XIAP, Apaf-1, AIFM1, ASK1, BAG3, Casein kinase 2, FANCC, GPR37, HSF1, MSR1, PARK2, PARP1, STUB1, and XRCC1
HSPA1A
Myosin Binding Protein H (MYBPH)
the shape, movement, and structural foundation of cells. MINT - PSICQUIC BAG3 Bcl2 Associated Athanogene 3 Affinity chromatography - 465 Physical association
MYBPH
Protein-coding gene in the species Homo sapiens
control during aging involves recruitment of the macroautophagy pathway by BAG3". EMBO J. 28 (7): 889–901. doi:10.1038/emboj.2009.29. PMC 2647772. PMID 19229298
BAG1
and developmental delay; 613076; GFER Myopathy, myofibrillar, BAG3-related; 612954; BAG3 Myopathy, myofibrillar, filamin C-related; 609524; FLNC Myopathy
List_of_OMIM_disorder_codes
Protein-coding gene in the species Homo sapiens
"Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3-modulated adhesion and invasion". The Journal of Pathology. 218 (4): 495–504
CYR61
Protein-coding gene in the species Homo sapiens
Grx2 has been shown to physically interact with MDH2, PITPNB, GPX4, CYCS, BAG3, and TXNRD1 in one independent high-throughput proteomic analysis. GRCh38:
GLRX2
BAG3
BAG3
BAG3
BAG3
Girl/Female
Sikh
Love for coast
Boy/Male
Arabic, Australian, Muslim
Happy; Lucky; Blissful
Male
Italian
Italian form of Roman Latin Liberius, LIBORIO means "free."
Girl/Female
Sikh
Olive, Fiery, Sower of seeds
Boy/Male
Indian, Kashmiri
Earth
Girl/Female
Arabic, Muslim
It is the Name of One of the Daughters of the Prophet; One who Allah Loves
Boy/Male
Tamil
Lord Krishna, Shiva
Boy/Male
Indian
The Greatest Teacher
Female
Czechoslovakian
, beloved of God, or, Lord, have mercy.
Girl/Female
Tamil
Mitshu | மீதà¯à®·à¯à®‚
Light
BAG3
BAG3
BAG3
BAG3
BAG3