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BRD9

  • BRD9
  • Mammalian protein found in Homo sapiens

    the BRD9 gene. BRD9 contains a bromodomain. It is closely related to BRD7. BRD9 is present in some SWI/SNF ATPase remodeling complexes. The BRD9 gene

    BRD9

    BRD9

    BRD9

  • Bromodomain
  • Protein domain

    non-BET bromodomain proteins BRD7 and BRD9 have also been developed. Chromodomain BET inhibitor BRD2 BRD3 BRD4 BRD7 BRD9 BRDT PDB: 1e6i​; Owen DJ, Ornaghi

    Bromodomain

    Bromodomain

    Bromodomain

  • Mammalian SWI/SNF (BAF) complex
  • Chromatin remodeling complex

    composition of the ncBAF complex (i.e. Bromodomain-containing protein 9 -BRD9- subunit) makes it an attractive target for drug development efforts. The

    Mammalian SWI/SNF (BAF) complex

    Mammalian_SWI/SNF_(BAF)_complex

  • Poison exon
  • Biological phenomenon

    splicing factor SF3B1 have been found to promote PE inclusion in BRD9, reducing BRD9 mRNA and protein levels and leading to melanomagenesis. Mutations

    Poison exon

    Poison_exon

  • Molecular glue
  • Class of chemical compounds

    polymerization and proteasomal degradation. AMPTX-1 (BRD9-DCAF16) Recruits DCAF16 E3 ligase to degrade BRD9. dGEM3 (V) HL-GEMIN3] Links GEMIN3 to VHL E3 ligase

    Molecular glue

    Molecular glue

    Molecular_glue

  • Diana Hargreaves
  • American biologist

    Lee DS, Kelso TWR, Shokhirev MN, Dixon JR, Hargreaves DC. A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency

    Diana Hargreaves

    Diana Hargreaves

    Diana_Hargreaves

  • List of human protein-coding genes 1
  • HGNC:13575; O60885 1657 BRD7 HGNC:14310; Q9NPI1 1658 BRD8 HGNC:19874; Q9H0E9 1659 BRD9 HGNC:25818; Q9H8M2 1660 BRD10 HGNC:23378; Q5HYC2 1661 BRDT HGNC:1105; Q58F21

    List of human protein-coding genes 1

    List_of_human_protein-coding_genes_1

  • Nuclear protein in testis gene
  • 1,132-amino acid

    cases, 10 fusion partners of NUTM1 were identified: ACIN1-NUTM1 (24 cases), BRD9-NUTM1 (10 cases), CUX1-NUTM1 (15 cases), ZNF618-NUTM1 (9 cases; ZNF618 is

    Nuclear protein in testis gene

    Nuclear_protein_in_testis_gene

  • SWI/SNF
  • Subfamily of ATP-dependent chromatin remodeling complexes

    Nathanael S.; Bradner, James E. (2018-11-15). "Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma". eLife. 7 e41305

    SWI/SNF

    SWI/SNF

    SWI/SNF

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Online names & meanings

  • Katja
  • Girl/Female

    Greek

    Katja

    Pure.

  • Deewakar | திவாகர
  • Boy/Male

    Tamil

    Deewakar | திவாகர

    The Sun, Lord of light

  • Shillington
  • Surname or Lastname

    English

    Shillington

    English : habitational name from a place in Bedfordshire, so named from an unattested Old English personal name, Scyttel + -inga- (genitive plural) ‘belonging to the people of’ + dūn ‘hill’.

  • Ehi
  • Biblical

    Ehi

    my brother

  • Rudransh
  • Boy/Male

    Hindu

    Rudransh

    Lord Shiva

  • Jivati
  • Girl/Female

    Hindu

    Jivati

    Live

  • Yellen
  • Surname or Lastname

    English

    Yellen

    English : probably a variant of Yelland or Yellin.Americanized spelling of Norwegian Hjellen, from the definite singular form of Old Norse hjallr ‘terrace’, ‘ledge’ (see Hjelle).Jewish (Ashkenazic) : variant spelling of Jelen.

  • Ujjay | உஜ்ஜய
  • Boy/Male

    Tamil

    Ujjay | உஜ்ஜய

    Victorious

  • Vrusath | வரஸத
  • Boy/Male

    Tamil

    Vrusath | வரஸத

    Prosperity

  • Mukthi
  • Girl/Female

    Hindu

    Mukthi

    Salvation, Freedom from life and death

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