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AuTophaGy related 1 (Atg1) is a 101.7kDa serine/threonine kinase in S.cerevisiae, encoded by the gene ATG1. It is essential for the initial building of
Atg1
Cell biology structure
other known players such as Atg1, Atg13 and Atg17. Atg1 is a kinase upregulated upon induction of autophagy. Atg13 regulates Atg1 and together they form a
Autophagosome
Rab1 mediates the recruitment of Atg1 to the PAS. Rab1 regulates macroautophagy by recruiting its effector, Atg1, to the PAS to tether Atg9 vesicles
RAB1
Enzyme found in humans
important protein in autophagy for mammalian cells, and is homologous to ATG1 in yeast. It is part of the ULK1-complex, which is needed in early steps
ULK1
Process of cells digesting parts of themselves
phosphorylation of the Unc-51-like kinases ULK1 and ULK2 (mammalian homologues of Atg1). Induction of autophagy results in the dephosphorylation and activation
Autophagy
Protein-coding gene in humans
extracellular space guanyl-nucleotide exchange factor complex cytoplasm Atg1/ULK1 kinase complex axonal growth cone main axon P-body membrane axon dendrite
C9orf72
Military unit
1953. VF-52 embarked on the USS Wasp for a WestPac deployment as part of ATG1 from 1 Sep 1954 to 11 Apr 1955. VF-52 embarked on the USS Lexington for a
VF-52
Increase of the total mass of a cell
normally directly inhibits the function of the autophagy inducing kinase Atg1/ULK1. Thus, reducing TOR activity both reduces the global rate of translation
Cell_growth
Protein-coding gene in the species Homo sapiens
site at serine 23. C1orf112 has been found experimentally to interact with ATG1, an aldosterone secretion whose overexpression characterizes certain forms
C1orf112
Protein-coding gene in the species Homo sapiens
cytosol cytoplasm GATOR2 complex nucleotide-activated protein kinase complex Atg1/ULK1 kinase complex TORC2 complex Biological process mitochondrial DNA metabolic
SESN2
Death of a cell mediated by intracellular program, often as part of development
-1, -2, and -3 (ULK1, ULK2, UKL3), which play a similar role as the yeast Atg1, act downstream of the mTOR complex. ULK1 and ULK2 form a large complex with
Programmed_cell_death
British-American biochemist (born 1973)
Dimitra; Mollapour, Mehdi (2023-07-25). "Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery"
Mehdi_Mollapour
Protein-coding gene in the species Homo sapiens
activity Cellular component phagophore assembly site membrane nuclear membrane Atg1/ULK1 kinase complex phagophore assembly site nucleus cytoplasm endoplasmic
RB1CC1
Protein-coding gene in the species Homo sapiens
protein binding protein kinase binding Cellular component cytoplasm cytosol Atg1/ULK1 kinase complex mitochondrion phagophore assembly site endoplasmic reticulum
Autophagy-related_protein_13
Protein complex
preventing it from entering the ULK1 kinase complex, which consists of Atg1, Atg17, and Atg101. This prevents the structure from entering the preautophagosomal
MTORC1
ATG1
ATG1
ATG1
ATG1
Boy/Male
Tamil
Lord of Jain
Boy/Male
Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Lord Shiva
Male
Yiddish
(לֵב) Yiddish name LEV means "lion." In use by the Russians. Compare with other forms of Lev.
Boy/Male
English American
From the king's village or estate 'King's field.' King is one of several titles occasionally used...
Boy/Male
Tamil
Tiranand | தீரà¯à®°à®¾à®¨à®‚த
Lord Shiva
Boy/Male
Tamil
Garden
Male
Dutch
, supplanter.
Boy/Male
Tamil
Sankeerth | ஸஂகிரà¯à®¤
To practice
Girl/Female
Indian
Courageous
Boy/Male
Indian, Punjabi, Sikh
Divine
ATG1
ATG1
ATG1
ATG1
ATG1