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Enzyme
Adenosine kinase (AdK; EC 2.7.1.20) is an enzyme that catalyzes the transfer of gamma-phosphate from Adenosine triphosphate (ATP) to adenosine (Ado) leading
Adenosine_kinase
Energy-carrying molecule in living cells
Adenosine triphosphate (ATP) is a nucleoside triphosphate that provides free energy of approximately 58 kJ/mol (0.6 eV) to drive and support many processes
Adenosine_triphosphate
Enzyme in glycolysis
sugar kinases. Other members of this family (also known as the Ribokinase family) include ribokinase (RK), adenosine kinase (AK), inosine kinase, and
Phosphofructokinase
Chemical compound
monophosphates, including adenosine monophosphate, are formed. AMP can be regenerated to ATP as follows: AMP + ATP → 2 ADP (adenylate kinase in the opposite direction)
Adenosine_monophosphate
Class of enzymes
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular
AMP-activated_protein_kinase
Protein-coding gene in the species Homo sapiens
Adenosine kinase is an enzyme that in humans is encoded by the ADK gene. This gene encodes adenosine kinase, an abundant enzyme in mammalian tissues.
ADK_(gene)
Class of enzymes
catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction
Creatine_kinase
Class of enzymes
phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP. Pyruvate kinase was inappropriately named
Pyruvate_kinase
Cellular second messenger
Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells
Cyclic adenosine monophosphate
Cyclic_adenosine_monophosphate
Chemical compound
Researchers believe that co-targeting DNA-dependent protein kinase and poly(adenosine diphosphate-ribose) polymerase-1 does not promote apoptosis or
Adenosine_diphosphate_ribose
Chemical compound
monophosphate. AICAR is an analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. The drug has
AICA_ribonucleotide
Class of enzymes
Adenylate kinase (EC 2.7.4.3) (also known as ADK or myokinase) is a phosphotransferase enzyme that catalyzes the interconversion of the various adenosine phosphates
Adenylate_kinase
Topics referred to by the same term
Greater Manchester, England, UK Adenosine kinase, an enzyme that catalyzes the transfer of gamma-phosphate from ATP to adenosine ADK (gene), the gene that in
ADK
Chemical compound
Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of
Adenosine_diphosphate
Subphylum of chordates
synthesis elongation factor-2, eukaryotic translation initiation factor 3, adenosine kinase and a protein related to ubiquitin carboxyl-terminal hydrolase). A
Vertebrate
Pharmaceutical compound
experimental drug that acts as a selective inhibitor of the enzyme adenosine kinase. In animal studies it has analgesic and anticonvulsant effects. Erion
GP3269
Pharmaceutical compound
experimental drug that acts as a selective inhibitor of the enzyme adenosine kinase. In animal studies it has analgesic and antiinflammatory effects, and
ABT-702
Abnormally large head size
MedGen: Achondroplasia Acrocallosal syndrome Adams-Oliver syndrome Adenosine kinase deficiency Antley-Bixler syndrome Autosomal dominant Kenny-Caffey syndrome
Macrocephaly
Enzyme catalyzing transfer of phosphate groups onto specific substrates
Kinases are pervasive, the human genome codes for about 500 of these enzymes. Kinases are part of the larger family of phosphotransferases. Kinases should
Kinase
Pharmaceutical compound
experimental drug that acts as a selective inhibitor of the enzyme adenosine kinase. In animal studies it has analgesic and antiinflammatory effects. Fleurisson
A-286501
Class of enzymes
inosine-guanosine kinase, and inosine kinase (phosphorylating). This enzyme participates in purine metabolism. Park J, Gupta RS: Adenosine kinase and ribokinase--the
Inosine_kinase
Chemical compound
complex creatine kinase. Phosphocreatine is able to donate its phosphate group to convert adenosine diphosphate (ADP) into adenosine triphosphate (ATP)
Phosphocreatine
Enzyme
3-bisphosphoglyceric acid (1,3-BPG) to adenosine diphosphate (ADP) producing 3-phosphoglyceric acid (3-PG) and adenosine triphosphate (ATP): 1,3-bisphospho-D-glyceric
Phosphoglycerate_kinase
Family of enzymes
kinase (AMP-activated protein kinase). Protein kinase A, more precisely known as adenosine 3',5'-monophosphate (cyclic AMP)-dependent protein kinase,
Protein_kinase_A
Enzyme that adds phosphate groups to other proteins
protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which
Protein_kinase
Antiviral drug
2023. GS-441524 nucleoside is phosphorylated by nucleoside kinases (probably adenosine kinase (ADK), which is the enzyme that phosphorylates the structurally
GS-441524
Mammalian protein found in humans
double-stranded RNA-specific adenosine deaminase enzyme family are encoded by the ADAR family genes. ADAR stands for adenosine deaminase acting on RNA. This
ADAR
increased expression of the adenosine kinase (ADK). The increase in adenosine kinase results in an increased metabolic rate for adenosine nucleosides. Due to
Gene_therapy_for_epilepsy
Class of enzymes
Deoxycytidine can be phosphorylated by deoxycytidine kinase. Adenosine uses the enzyme adenosine kinase, which is a very important enzyme in the cell. Attempts
Purine nucleoside phosphorylase
Purine_nucleoside_phosphorylase
Protein family
adenylylsulfate kinase (phosphorylating), 5'-phosphoadenosine sulfate kinase, adenosine 5'-phosphosulfate kinase, adenosine phosphosulfate kinase, adenosine phosphosulfokinase
Adenylyl-sulfate_kinase
Cell surface receptor found in humans
The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A2b receptor gene which
Adenosine_A2B_receptor
InterPro Family
sugar kinases. Protein Sci 1993, 2: 31-40. Maj MC, Singh B, Gupta RS: Pentavalent ions dependency is a conserved property of adenosine kinase from diverse
1-phosphofructokinase
Medical condition
Pyruvate kinase is the last enzyme involved in the glycolytic process, transferring the phosphate group from phosphenol pyruvate to a waiting adenosine diphosphate
Pyruvate_kinase_deficiency
Group of simple sugar and carbohydrate compounds
kinases". Protein Science. 2 (1): 31–40. doi:10.1002/pro.5560020104. PMC 2142297. PMID 8382990. Park, Jae; Gupta, Radhey S. (2008). "Adenosine kinase
Ribose
family of sugar kinases. Other members of this family (also known as the RK family) include adenosine kinase (AK), inosine-guanosine kinase, fructokinase
Ribokinase
Drug typically used in cancer treatment
A tyrosine kinase inhibitor (TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activation
Tyrosine_kinase_inhibitor
Chemical compound
can be converted by adenosine kinase into its mono-, di-, and triphosphate forms. These active metabolites mimic natural adenosine nucleotides and compete
Tubercidin
Chemical compound
8-Bromoadenosine 3',5'-cyclic adenosine monophosphate (8-Br-cAMP) is a brominated derivative of cyclic adenosine monophosphate (cAMP). 8-Br-cAMP is an
8-Bromoadenosine 3',5'-cyclic monophosphate
8-Bromoadenosine_3',5'-cyclic_monophosphate
Class of protein kinase enzymes
PMID 4312674. Langan TA (1969). "Action of adenosine 3',5'-monophosphate-dependent histone kinase in vivo". J. Biol. Chem. 244 (20): 5763–5. doi:10
Serine/threonine-specific protein kinase
Serine/threonine-specific_protein_kinase
Mammalian protein found in humans
also known as mammalian target of rapamycin is a serine-threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival
MTOR
Enzyme
In enzymology, an ADP—thymidine kinase (EC 2.7.1.118) is an enzyme that catalyzes the chemical reaction ADP + thymidine ⇌ {\displaystyle \rightleftharpoons
ADP—thymidine_kinase
Chemical compound
2008). "Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases". Journal of Immunology
Deoxyadenosine_triphosphate
Class of four receptor proteins to the molecule adenosine
The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand. There are four
Adenosine_receptor
Cell surface receptor found in humans
The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it. This protein is a member of the
Adenosine_A2A_receptor
Chemical compound
adenosine triphosphate (ATP), primarily in muscle and brain tissue. Its phosphorylated form, phosphocreatine, donates phosphate groups to adenosine diphosphate
Creatine
Putative drug class for treating cancer
Aurora-2-adenosine complex has been determined. The hinge (yellow), glycine-rich loop (blue), and activation loop (red) are key features of the protein kinase
Aurora_inhibitor
Metabolic disorder leading to muscle dysfunction
Adenosine monophosphate deaminase deficiency type 1 or AMPD1, is a human metabolic disorder in which the body consistently lacks the enzyme AMP deaminase
Adenosine monophosphate deaminase deficiency type 1
Adenosine_monophosphate_deaminase_deficiency_type_1
Chemical compound
3′-Phosphoadenosine-5′-phosphosulfate (PAPS) is a derivative of adenosine monophosphate (AMP) that is phosphorylated at the 3′ position and has a sulfate
3'-Phosphoadenosine-5'-phosphosulfate
3'-Phosphoadenosine-5'-phosphosulfate
Class of enzymes
AMP—thymidine kinase (EC 2.7.1.114) is an enzyme that catalyzes the chemical reaction AMP + thymidine ⇌ {\displaystyle \rightleftharpoons } adenosine + thymidine
AMP—thymidine_kinase
Corticotropin-releasing hormone (CRH) Cortisol Creatine Creatine kinase Crystallin Cyclic adenosine monophosphate (cAMP) α-Cyclodextrin Cyclodextrin glycosyltransferase
List_of_biomolecules
Chemical compound
cyclic adenosine monophosphate (cAMP). Normally, cyclic adenosine monophosphate causes increased activation of protein kinase A (PKA). Protein kinase A is
Milrinone
Enzyme
pentavalent ions. Pentavalent ions dependency is a conserved property of adenosine kinase from diverse sources: identification of a novel motif implicated in
Tagatose-6-phosphate_kinase
Method of stimulus sensing and response in cells
Two-component systems typically consist of a membrane-bound histidine kinase that senses a specific environmental stimulus, and a corresponding response
Two-component regulatory system
Two-component_regulatory_system
Cyclic nucleic acid
nitrogenous base, and a single phosphate group. As can be seen in the cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) images
Cyclic_nucleotide
Investigational Parkinson's disease drugs
D1 and D5 receptor agonist [13] BHV-8000 (TLL-041) – Janus kinase 1 inhibitor and TYK2 kinase inhibitor [14] Mesdopetam (IRL-790) – dopamine D2 and D3 receptor
List of investigational Parkinson's disease drugs
List_of_investigational_Parkinson's_disease_drugs
Intracellular energy shuttle in muscles
myofibrils. This is part of phosphocreatine metabolism. In mitochondria, Adenosine triphosphate (ATP) levels are very high as a result of glycolysis, TCA
Creatine_phosphate_shuttle
Terrossian E (1966). "Sur la nouvelle acide adenosine 5'-triphosphorique:guanidine phosphotransferase, l'opheline kinase". Biochim. Biophys. Acta. 113: 542–550
Opheline_kinase
Enzyme
aerogenes. II. Phosphorylation of cellobiose with adenosine 5'-triphosphate by a -glucoside kinase". J. Biol. Chem. 247 (11): 3415–9. doi:10.1016/S0021-9258(19)45156-9
Beta-glucoside_kinase
Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21 that catalyzes
Thymidine kinase in clinical chemistry
Thymidine_kinase_in_clinical_chemistry
20: adenosine kinase EC 2.7.1.21: thymidine kinase EC 2.7.1.22: ribosylnicotinamide kinase EC 2.7.1.23: NAD+ kinase EC 2.7.1.24: dephospho-CoA kinase EC
List_of_EC_numbers_(EC_2)
Drug class
Shuralyova I, Coe IR (2004). "The adenosine transporter, mENT1, is a target for adenosine receptor signaling and protein kinase Cepsilon in hypoxic and pharmacological
Adenosine_reuptake_inhibitor
Protein domain
The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases are a group
Protein_kinase_domain
Chemical compound
43. PMID 8458030. Gaskin FS (2007). Mechanisms of adenosine monophosphate-activated protein kinase-induced preconditioning in ischemia/reperfusion (Report)
Acadesine
Enzyme
activation. In particular, movement of some parts of the kinase domain gives free access to adenosine triphosphate (ATP) and the substrate to the active site
Tyrosine_kinase
Chemical compound
adenosine monophosphate (cAMP) 8-Bromoguanosine 3',5'-cyclic monophosphate (8-Br-cGMP) Guanosine triphosphate (GTP) Guanylate cyclase Protein Kinase G
Cyclic guanosine monophosphate
Cyclic_guanosine_monophosphate
Widening of blood vessels
ways to increase blood flow, including releasing vasodilators, primarily adenosine, into the local interstitial fluid, which diffuses to capillary beds,
Vasodilation
Chemical compound
times less potent at inhibiting protein kinase G. It achieves this through competitive inhibition of the adenosine triphosphate (ATP) site on the PKA catalytic
H-89
Dephosphorylation enzyme
ATPases (EC 3.6.1.3, Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, ATP hydrolase, adenosine triphosphatase) are
ATPase
Enzyme involved in glycogenolysis
the direct transfer of phosphate from adenosine triphosphate (ATP) to the substrate serine. Phosphorylase kinase is a 1.3 MDa hexadecameric holoenzyme
Phosphorylase_kinase
Transdermal patch that releases caffeine into the body
levels of adenosine built up. The longer they stay awake, the more adenosine builds up and makes them feel sleepy. This happens because adenosine attaches
Caffeine_patch
Series of interconnected biochemical reactions
energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH)
Glycolysis
triphosphate-adenylate kinase, nucleoside triphosphate-adenosine monophosphate transphosphorylase, GTP:AMP phosphotransferase, and isozyme 3 of adenylate kinase. This
Nucleoside-triphosphate—adenylate kinase
Nucleoside-triphosphate—adenylate_kinase
Class of enzymes
Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange
Nucleoside-diphosphate_kinase
Chemical compound
can be phosphorylated to cytidine diphosphate by the enzyme CMP kinase, with adenosine triphosphate or guanosine triphosphate donating the phosphate group
Cytidine_monophosphate
Class of enzymes
In enzymology, a lombricine kinase (EC 2.7.3.5) is an enzyme that catalyzes the chemical reaction ATP + lombricine ⇌ {\displaystyle \rightleftharpoons
Lombricine_kinase
Chemical compound
Toyocamycin is a naturally occurring nucleoside antibiotic analog of adenosine. It was first isolated from the bacterium Streptomyces toyocaensis. It
Toyocamycin
Class of enzymes
In molecular biology, acetate kinase (EC 2.7.2.1), which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating
Acetate_kinase
Class of enzymes
In enzymology, an acylglycerol kinase (EC 2.7.1.94) is an enzyme that catalyzes the chemical reaction ATP + acylglycerol ⇌ {\displaystyle \rightleftharpoons
Acylglycerol_kinase
In enzymology, an ammonia kinase (EC 2.7.3.8) is an enzyme that catalyzes the chemical reaction ATP + NH3 ⇌ {\displaystyle \rightleftharpoons } ADP + phosphoramide
Ammonia_kinase
Central nervous system stimulant
blocking the binding of adenosine at a number of adenosine receptor types, inhibiting the centrally depressant effects of adenosine and enhancing the release
Caffeine
Protein family
JA, Asensio C (August 1978). "Distribution of adenosine 5'-triphosphate (ATP)-dependent hexose kinases in microorganisms". BioSystems. 10 (3): 265–82
Fructosamine_kinase_family
Human chromosome
complete list, see the link in the infobox on the right. ADA: Adenosine Deaminase (Adenosine Deaminase Deficiency) ANDP: encoding protein Activity-dependent
Chromosome_20
Process
glutamine to glutamate. Both AMP and GMP can be phosphorylated by kinases to form adenosine triphosphate (ATP) and guanosine triphosphate (GTP), respectively
Nucleic_acid_metabolism
Class of enzymes
deoxycytidylate kinase, deoxycytidylate kinase, CMP kinase, CTP:CMP phosphotransferase, dCMP kinase, deoxycytidine monophosphokinase, UMP-CMP kinase, ATP:UMP-CMP
Cytidylate_kinase
Protein
AMP-regulated phosphoprotein. As such PPP1R1B affects dopamine, glutamate and adenosine; and there is some support for a role of the gene in schizophrenia, as
PPP1R1B
Cancer researcher
(2017-05-15). "Identification of a nucleoside analog active against adenosine kinase–expressing plasma cell malignancies". Journal of Clinical Investigation
Utthara_Nayar
Drug and first antibiotic identified by a deep learning algorithm
experimental drug that acts as an enzyme inhibitor of c-Jun N-terminal kinase (JNK). Originally, it was researched for the treatment of diabetes, but
Halicin
Class of cell surface receptors coupled to G-protein-associated intracellular signaling
(or cytoplasmic) receptor domain by protein kinases. Cyclic AMP-dependent protein kinases (protein kinase A) are activated by the signal chain coming
G_protein-coupled_receptor
In enzymology, an alkylglycerol kinase (EC 2.7.1.93) is an enzyme that catalyzes the chemical reaction ATP + 1-O-alkyl-sn-glycerol ⇌ {\displaystyle \rightleftharpoons
Alkylglycerol_kinase
913.696.620.010 – adenosine kinase MeSH D08.811.913.696.620.155 – choline kinase MeSH D08.811.913.696.620.175 – deoxycytidine kinase MeSH D08.811.913.696
List_of_MeSH_codes_(D08)
Class of enzymes
(vitamin B5) to form 4'-phosphopantothenate at the expense of a molecule of adenosine triphosphate (ATP). It is the rate-limiting step in the biosynthesis of
Pantothenate_kinase
Mammalian protein found in Homo sapiens
in humans is encoded by the AMPD1 gene. Adenosine monophosphate deaminase is an enzyme that converts adenosine monophosphate (AMP) to inosine monophosphate
AMP_deaminase
Medicine for respiratory diseases
In addition, it also reduces the airway responsiveness to allergens, adenosine, methacholine, and histamine by two distinct mechanisms: First, it acts
Tedral
Protein metabolic pathway
is low (ADP > ATP) by the adenylate kinase (myokinase) reaction. AMP is also produced from adenine and adenosine directly; however, AMP can be produced
Purine_nucleotide_cycle
and choline, whereas its two products are adenosine diphosphate (ADP) and O-phosphocholine. Choline kinase requires magnesium ions (+2) as a cofactor
Choline_kinase
High energy storage compounds
pool to be maintained in a concentration range, which, if it all were adenosine triphosphate (ATP), would create problems due to the ATP-consuming reactions
Phosphagen
Lethal venom produced by Synanceia verrucosa
β2-adrenoceptors are responsible for the activation of the cyclic adenosine monophosphate (cAMP)-protein kinase (PKA) pathway. The cAMP will phosphorylate muscle regulatory
Verrucotoxin
Protein-coding gene in the species Homo sapiens
synaptogenesis. The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the
Synapsin_I
Class of enzymes
In enzymology, arginine kinase (EC 2.7.3.3) is an enzyme that catalyzes the chemical reaction ATP + L-arginine ⇌ {\displaystyle \rightleftharpoons } ADP
Arginine_kinase
In enzymology, an ethanolamine kinase (EC 2.7.1.82) is an enzyme that catalyzes the chemical reaction ATP + ethanolamine ⇌ {\displaystyle \rightleftharpoons
Ethanolamine_kinase
ADENOSINE KINASE
ADENOSINE KINASE
ADENOSINE KINASE
ADENOSINE KINASE
Boy/Male
Bengali, Hindu, Indian, Traditional
Holder of the Flame
Girl/Female
Tamil
Vennela | வேநà¯à®¨à¯‡à®²à®¾
Moon light, Black Sky
Boy/Male
Biblical
Strong, mighty'.
Female
Native American
Native American Choctaw name NITA means "bear." Compare with other forms of Nita.
Boy/Male
Hindu, Indian, Traditional
King; Arjun
Boy/Male
Buddhist, Indian, Japanese
Ancient Reflection
Boy/Male
Indian, Punjabi, Sikh
Pure
Male
French
French form of Roman Latin Marcellus, MARCEL means "defense" or "of the sea."
Boy/Male
Indian
To give freely
Female
Celtic
, victory.
ADENOSINE KINASE
ADENOSINE KINASE
ADENOSINE KINASE
ADENOSINE KINASE
ADENOSINE KINASE
a.
Same as Adenose.
a.
Like a gland; full of glands; glandulous; adenous.