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Investigational antidepressant compound
Zelquistinel (GATE-251, formerly AGN-241751) is an orally active small-molecule NMDA receptor positive allosteric modulator which is under development
Zelquistinel
Glutamate receptor and ion channel protein found in nerve cells
glutamate site partial agonist Positive allosteric modulators include: Zelquistinel (GATE-251) – synthetic novel site partial agonist Apimostinel (GATE-202)
NMDA_receptor
Burgdorf JS, Zhang XL, Stanton PK, Moskal JR, Donello JE (December 2022). "Zelquistinel Is an Orally Bioavailable Novel NMDA Receptor Allosteric Modulator That
NMDA_receptor_modulator
Drugs that promote rapid and sustained neuroplasticity
TrkB. NMDA receptor modulators have also been explored in this vein. Zelquistinel, an NMDA receptor modulator, has shown rapid onset and sustained duration
Psychoplastogen
Investigational antidepressant compound
antagonists such as ketamine. List of investigational antidepressants Zelquistinel "Naurex's Novel Antidepressant GLYX-13 Recognized as One of Windhover's
Apimostinel
List of pharmaceutical drugs under clinical development for treatment of depression
TS-161 – metabotropic glutamate mGlu2 and mGlu3 receptor antagonist Zelquistinel (AGN-241751; GATE-251) – ionotropic glutamate NMDA receptor partial positive
List of investigational antidepressants
List_of_investigational_antidepressants
Chemical compound
(GATE-202, NRX-1074), a 2nd generation analog with improved potency, and zelquistinel (GATE-251, AGN-241751), a 3rd generation small molecule with improved
Rapastinel
Investigational antipsychotics
action (dopamine and serotonin receptor modulator) – schizophrenia [57] Zelquistinel (AGN-241751; GATE-251) – ionotropic glutamate NMDA receptor positive
List of investigational antipsychotics
List_of_investigational_antipsychotics
ZELQUISTINEL
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Male
Native American
Native American Alqonguin name MATCHITISIW means "he has bad character."
Boy/Male
Tamil
Good character
Boy/Male
Tamil
Kamalaksh | கமாலாகà¯à®·
With beautiful lotus type eyes
Girl/Female
Indian, Modern
Love; Kindness
Male
English
Anglicized form of Irish Gaelic Seán, SEAN means "God is gracious."
Boy/Male
Australian, Farsi
Name of a Medes King; Righteous
Boy/Male
Indian, Punjabi, Sikh
Beloved of God
Girl/Female
Hindu
Spirit of pink
Surname or Lastname
English
English : variant of Ketcham.
Male
Russian
(Феофил) Russian form of Latin Theophilus, FEOFIL means "God-friend."
ZELQUISTINEL
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