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STAT5A

  • STAT5A
  • Protein-coding gene in the species Homo sapiens

    encoded by the STAT5A gene. STAT5A orthologs have been identified in several placentals for which complete genome data are available. STAT5a shares the same

    STAT5A

    STAT5A

    STAT5A

  • STAT5
  • Protein family

    two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate

    STAT5

    STAT5

    STAT5

  • Lipogenesis
  • Biochemical process involving the production of fats

    proposed mechanism suggests that growth hormones may phosphorylate with STAT5A and STAT5B, transcription factors that are a part of the Signal Transducer

    Lipogenesis

    Lipogenesis

  • Erythropoietin receptor
  • Protein-coding gene in the species Homo sapiens

    Erythropoietin, Grb2, Janus kinase 2, LYN, PIK3R1, PTPN6, SOCS2, SOCS3, and STAT5A. GRCh38: Ensembl release 89: ENSG00000187266 – Ensembl, May 2017 GRCm38:

    Erythropoietin receptor

    Erythropoietin receptor

    Erythropoietin_receptor

  • STAT protein
  • Family of intracellular transcription factors

    family members that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1 homodimers are involved in type II interferon

    STAT protein

    STAT protein

    STAT_protein

  • STAT4
  • Protein-coding gene in the species Homo sapiens

    belonging to the STAT protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6. STAT proteins are key activators of gene transcription which

    STAT4

    STAT4

    STAT4

  • JAK-STAT signaling pathway
  • Biological signaling pathway h

    to) proteins. There are seven STAT proteins: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. STAT proteins contain many different domains, each with

    JAK-STAT signaling pathway

    JAK-STAT_signaling_pathway

  • Chromosome 17
  • Human chromosome

    family: SLFN5, SLFN11, SLFN12, SLFN12L, SLFN13, SLFN14 STAT proteins: STAT3, STAT5A, STAT5B Tubulins: TUBD1, TUBG1, TUBG2 Ubiquitin-conjugating enzymes: UBE2G1

    Chromosome 17

    Chromosome 17

    Chromosome_17

  • CRKL
  • Protein-coding gene in the species Homo sapiens

    GAB1, GAB2, INPP5D, MAP4K1, MAP4K5, NEDD9, PIK3R2, Paxillin RAPGEF1, RICS, STAT5A, Syk, and WAS. Crk GRCh38: Ensembl release 89: ENSG00000099942 – Ensembl

    CRKL

    CRKL

    CRKL

  • List of human protein-coding genes 8
  • P52630 15953 STAT3 HGNC:11364; P40763 15954 STAT4 HGNC:11365; Q14765 15955 STAT5A HGNC:11366; P42229 15956 STAT5B HGNC:11367; P51692 15957 STAT6 HGNC:11368;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • List of human transcription factors
  • ENSG00000138378 STAT Known motif – In vivo/Misc source [888] BDHTTCTBGKAAD STAT5A ENSG00000126561 STAT Known motif – In vivo/Misc source [889] YTTCYNRGAAHY

    List of human transcription factors

    List_of_human_transcription_factors

  • Epidermal growth factor receptor
  • Transmembrane protein

    PTPN11, PTPN6, PTPRK, SH2D3A, SH3KBP1, SHC1, SOS1, Src, STAT1, STAT3, STAT5A, UBC, and WAS, PAR2. In fruitflies, the epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal_growth_factor_receptor

  • SH2 domain
  • Protein domain

    SOCS3; SOCS4; SOCS5; SOCS6; SOCS7 SRC; SRMS STAT1; STAT2; STAT3; STAT4; STAT5A; STAT5B; STAT6 SUPT6H; SYK TEC; TENC1; TNS; TNS1; TNS3; TNS4; TXK VAV1;

    SH2 domain

    SH2 domain

    SH2_domain

  • STAT5B
  • Protein-coding gene in the species Homo sapiens

    1996). "Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells". J. Biol. Chem. 271 (18):

    STAT5B

    STAT5B

    STAT5B

  • Janus kinase 1
  • Mammalian protein found in Homo sapiens

    with: ELP2, GNB2L1 IL6ST, Grb2, IL2RB, IRS1, IL10RA, PTPN11, STAM2, STAT3, STAT5A, STAT5B, and TNFRSF1A. Janus kinase inhibitor GRCh38: Ensembl release 89:

    Janus kinase 1

    Janus kinase 1

    Janus_kinase_1

  • MAPK1
  • Protein-coding gene in the species Homo sapiens

    Phosphatidylethanolamine binding protein 1, RPS6KA1, RPS6KA2, RPS6KA3, SORBS3, STAT5A, TNIP1, TOB1, TSC2, UBR5, and VAV1. Mutations in MAPK1 are implicated in

    MAPK1

    MAPK1

    MAPK1

  • Veronika Sexl
  • Austrian pharmacologist and toxicologist

    Veronika Sexl; Roland Piekorz; Richard Moriggl; et al. (15 September 2000). "Stat5a/b contribute to interleukin 7–induced B-cell precursor expansion, but abl-

    Veronika Sexl

    Veronika Sexl

    Veronika_Sexl

  • Janus kinase 2
  • Non-receptor tyrosine kinase and coding gene in humans

    IRS1 IL12RB2 IL5RA PIK3R1 PPP2R4 PTK2 PTPN11 PTPN6 PRMT5 SH2B1 SHC1 SOCS3 STAT5A STAT5B STAM SOCS1 TEC TNFRSF1A VAV1 YES1 Prolactin signals through JAK2

    Janus kinase 2

    Janus kinase 2

    Janus_kinase_2

  • PTPN11
  • Protein-coding gene in humans

    LRP1, PDGFRB, PI3K → Akt PLCG2, PTK2B, Ras SLAMF1, SOCS3, SOS1, STAT3, STAT5A, and STAT5B. Inhibitors Batoprotafib SHP099 Sitneprotafib Vociprotafib (RMC-4630)

    PTPN11

    PTPN11

    PTPN11

  • ERBB4
  • Protein-coding gene in the species Homo sapiens

    lateral sclerosis type 19. ERBB4 has been shown to interact with: DLG4 NRG1, STAT5A, and YAP1. GRCh38: Ensembl release 89: ENSG00000178568 – Ensembl, May 2017

    ERBB4

    ERBB4

    ERBB4

  • CBX5 (gene)
  • Protein-coding gene in humans

    Ku70, Lamin B receptor, MBD1, MIS12, SMARCA4, SUV39H1, TAF4, and TRIM28. STAT5A, Heterochromatin protein 1 GRCh38: Ensembl release 89: ENSG00000094916 –

    CBX5 (gene)

    CBX5 (gene)

    CBX5_(gene)

  • FMS-like tyrosine kinase 3 ligand
  • Protein-coding gene in the species Homo sapiens

    v t e Regulome Activates MAP kinase, FLT3, STAT5A Inhibits tyrosine kinase, PSA

    FMS-like tyrosine kinase 3 ligand

    FMS-like tyrosine kinase 3 ligand

    FMS-like_tyrosine_kinase_3_ligand

  • CFU-E
  • Progenitor cell to a red blood cell

    Carlo; Lodish, Harvey F. (2001-12-01). "Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts". Blood. 98

    CFU-E

    CFU-E

    CFU-E

  • Anne Rosenberg
  • American surgical oncologist

    PMID 19664288. "Prolactin Inhibits BCL6 Expression in Breast Cancer through a Stat5a-Dependent Mechanism" Cancer Research Journal. Retrieved 2019-08-04. Peck

    Anne Rosenberg

    Anne_Rosenberg

  • Mammary analogue secretory carcinoma
  • Salivary gland neoplasm

    crest origin cells and development of the peripheral nervous system), and STAT5A (a transcription factor) but lack antibody-detectable TP63 (a transcription

    Mammary analogue secretory carcinoma

    Mammary_analogue_secretory_carcinoma

  • N-myc-interactor
  • Protein-coding gene in the species Homo sapiens

    leukemias. NMI (gene) has been shown to interact with BRCA1, IFI35, Myc, and STAT5A, and TUBA3C. GRCh38: Ensembl release 89: ENSG00000123609 – Ensembl, May

    N-myc-interactor

    N-myc-interactor

    N-myc-interactor

  • NEDD9
  • Protein-coding gene in the species Homo sapiens

    binding sites for a number of additional transcription factors, including STAT5A and NF-kappa B. In the 3'UTR of NEDD9 is a match to positions 2-8 of mature

    NEDD9

    NEDD9

    NEDD9

  • N-alpha-acetyltransferase 10
  • Protein-coding gene in the species Homo sapiens

    Min L, Han Y, Meng L, Liu C, Xie Y, et al. (October 2014). "Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis". Carcinogenesis

    N-alpha-acetyltransferase 10

    N-alpha-acetyltransferase 10

    N-alpha-acetyltransferase_10

  • Embryonal fyn-associated substrate
  • Protein-coding gene in the species Homo sapiens

    Marignol L, Ree AH (2013). "Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer". PLOS ONE. 8 (5)

    Embryonal fyn-associated substrate

    Embryonal_fyn-associated_substrate

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Online names & meanings

  • Pasupathi
  • Boy/Male

    Hindu, Indian, Tamil

    Pasupathi

    Lord Shiva

  • Humeira
  • Girl/Female

    Indian

    Humeira

    A beautiful Raaga musical scale in hindustani indian music

  • Stanbury
  • Boy/Male

    Anglo, Australian, British, English

    Stanbury

    From the Stone Fortification

  • Kumaran | குமாரந 
  • Boy/Male

    Tamil

    Kumaran | குமாரந 

    Lord muraga (Son of Shivan)

  • Kawakib
  • Girl/Female

    Arabic, Muslim

    Kawakib

    Star

  • Courtnay
  • Girl/Female

    British, English

    Courtnay

    Court-dweller

  • Svenhilde
  • Girl/Female

    Norse

    Svenhilde

    Swan or warrior.

  • ASROMIAMUN
  • Male

    Egyptian

    ASROMIAMUN

    , an unidentified king.

  • Navadeep
  • Boy/Male

    Hindu, Indian, Tamil

    Navadeep

    Light

  • Razzak
  • Boy/Male

    Arabic, Muslim, Pashtun

    Razzak

    Protector

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STAT5A

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