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Mouse assay for heritable germline mutation
The specific-locus test (SLT) is a genetic test to assess the impact of mutagens such as radiation or chemicals on mutation rates in a selected set of
Specific-locus_test
British-American geneticist (1910–2003)
the genetic effects of radiation and chemicals. He developed the specific-locus test in mice for measuring mutation rates. Russell's work was used as
William L. Russell (geneticist)
William_L._Russell_(geneticist)
Chemical compound
generation itself. This approach, the specific locus test (SLT) allowed Russell to study a wide range of specific mutations and to calculate the mutation
ENU
Topics referred to by the same term
Social learning theory, a psychological explanation for behaviour Specific-locus test, an mouse assay for measuring mutations from radiation or chemical
SLT
blotting Spacer DNA Speciation Speciation (genetic algorithm) Species Specific-locus test Spectral karyotype Sperm Spermatid Spermatocyte Spermatogenesis Spermatogonium
Index_of_genetics_articles
Concept in psychology
Locus of control is the degree to which people believe that they, as opposed to external forces (beyond their influence), have control over the outcome
Locus_of_control
Chemical compound
laboratory mice, with the impact on mutagenesis measured by the specific-locus test by Bruce Cattanach. Altretamine Thiotepa Wong JR, Morton LM, Tucker
Triethylenemelamine
location. Interpretations are submitted by clinical testing laboratories, research laboratories, locus-specific databases, UniProt, expert panels and practical
ClinVar
Genomic loci that explain variation in gene expression levels
locus (eQTL) is a type of quantitative trait locus (QTL), a genomic locus (region of DNA) that is associated with phenotypic variation for a specific
Expression quantitative trait loci
Expression_quantitative_trait_loci
Theoretical source of visible light
when illuminant A was standardized). This difference shifted the Planckian locus, changing the color temperature of the illuminant from its nominal 2848 K
Standard_illuminant
diagnostics, testing for rRNA in bacteria using restriction enzyme digestion and Southern blot technology. Multiple-locus VNTR analysis is a test used to detect
Diagnostic_microbiology
Fantasy book series by Adrian Tchaikovsky
2026-01-10. "2022 BSFA Awards Winners". Locus Online. 2023-04-10. Retrieved 2026-02-07. "2024 Locus Awards Winners". Locus Online. 2024-06-23. Retrieved 2026-02-07
The_Tyrant_Philosophers
Genes on human chromosome 6
designate a specific allele at a given HLA locus. HLA loci can be further classified into MHC class I and MHC class II (or rarely, D locus). Every two
Human_leukocyte_antigen
Biological process of yeast
differentiation. A yeast cell's mating type is determined by a specific genetic locus known as MAT, which governs its mating behaviour. Haploid yeast
Mating_of_yeast
the functional consequences in the literature and in gene variant or locus-specific databases (LSDBs). Mutalyzer is used by the Leiden Open Variation Database
Mutalyzer
Variant of DNA sequence at a locus
is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. Alleles can differ at a single position through single-nucleotide
Allele
Rare blood type
enzymes with very similar substrate specificities: the H locus (FUT1) which encodes the fucosyl transferase and the Se locus (FUT2) that instead indirectly
Hh_blood_group
Microbiological method for rapid identification
obtained are phenotypic traits. DNA sequence-based methods, including multi-locus sequence typing and even whole-genome sequencing, are increasingly used
Analytical_profile_index
Biological DNA analysis for allele repeats
evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies
STR_analysis
Laboratory technique
genotypes that are based on the length of specific DNA fragments or number of short tandem repeats (STR) at a specific locus by comparing the sample to internal
Electropherogram
Medical condition caused by chromosomal abnormality
diagnosis difficult. Children with DiGeorge syndrome have a specific profile in neuropsychological tests. They usually have a below-borderline normal IQ, with
DiGeorge_syndrome
American psychologist
psychologist known for developing social learning theory and research into locus of control. He was a faculty member at Ohio State University and then the
Julian_Rotter
Statistical modeling method
The response variable might be a measure of student achievement such as a test score, and different covariates would be collected at the classroom, school
Linear_regression
Generalization of the one-dimensional normal distribution to higher dimensions
normal distribution has a slightly different form. Each iso-density locus — the locus of points in k-dimensional space each of which gives the same particular
Multivariate normal distribution
Multivariate_normal_distribution
Method to evaluate biological samples
conjunction with CGH techniques, the more specific form of array CGH (aCGH) has been developed, allowing for a locus-by-locus measure of CNV with increased resolution
Comparative genomic hybridization
Comparative_genomic_hybridization
Nonfunctional allele caused by a genetic mutation
is an allele at a microsatellite locus that does not amplify to detectable levels in a polymerase chain reaction test. Microsatellite regions are usually
Null_allele
Genetics behind dog coat
different brown alleles cause specific shades or hues of brown. B is dominant to b. The melanophilin gene (MLPH) at the D locus causes a dilution mainly of
Dog_coat_genetics
Psychological attribute
particular test") whereas a pessimist might think, for example, "I'm never good at tests". This distinction covers global versus local and/or specific and the
Explanatory_style
Property of light based on human perception
lines, but no longer perpendicular to the locus. Judd's idea of determining the nearest point to the Planckian locus on a uniform chromaticity space is current
Correlated_color_temperature
Psychological theory on internal motivation
significant function. The informational aspect facilitates an internal perceived locus of causality and perceived competence, thus positively influencing intrinsic
Cognitive_evaluation_theory
Biological test for adaptive evolution
selection G-test Negative selection (natural selection) Ka/Ks ratio McDonald, J. H. Kreitman (1991). "Adaptive protein evolution at the Adh locus in Drosophila"
McDonald–Kreitman_test
Hypothesized anatomical detail
researchers believe these findings make it possible for women to have a rapid test to confirm whether or not they have a G-spot. Professor of genetic epidemiology
G-spot
Accuracy of light source in showing color of objects
source by finding the closest point to the Planckian locus on the (u, v) chromaticity diagram. If the test source has a CCT < 5000 K, use a black body for
Color_rendering_index
Place where a name-bearing type specimen was collected
they deliberately sampled topotypic material from the locus classicus of each species to test whether named taxa corresponded to phylogenetically distinct
Type_locality_(biology)
Psychological behavior
attribution error Gaslighting Learned industriousness Learned optimism Locus of control Pervasive refusal syndrome Pit of despair Self-handicapping Somebody
Learned_helplessness
Genetic profiling for legal evidence
large amounts of DNA material that was previously required. The DQ alpha 1 locus (or location) was also polymorphic and had multiple different alleles that
Forensic_DNA_analysis
Group of genes from one parent
(such as SNPs) on the same chromosome. Assume the first locus has alleles A or T and the second locus G or C. Both loci, then, have three possible genotypes:
Haplotype
DNA analysis method
two bead types for each CpG (or "CG", as per Figure 1) site per locus. Each locus tested is differentiated by different bead types. Both bead types are
Illumina_Methylation_Assay
Types of dementia involving the frontal or temporal lobes
neuropsychological tests are sensitive to the dysfunction of orbitofrontal cortex, yet are not specific to it. The weakness of these tests is that they do
Frontotemporal_dementia
2025 novel by John Scalzi
Scalzi". SFFWorld. 2025. Retrieved November 4, 2025. "2026 Locus Awards Top Ten Finalists". Locus Online. April 13, 2026. Retrieved April 18, 2026. John Scalzi's
The_Shattering_Peace
2025 fantasy novel by R. F. Kuang
Association. "2025 Nebula Awards Winners". Locus. June 6, 2026. Retrieved June 9, 2026. "2026 Locus Awards Winners". Locus Online. May 30, 2026. Retrieved May
Katabasis_(novel)
All points in space which project onto the same points in the retinas of both eyes
extended as a geometrical locus of points in space where a specific condition is met: the binocular horopter is the locus of iso-disparity points in
Horopter
Horse coat color pattern
found in many horse breeds. While the specific mutation responsible for roan has not been exactly identified, a DNA test can determine zygosity for roan in
Roan_(horse)
American writer and television producer (born 1948)
Hugo Award, World Fantasy Award, Locus Poll Award, and the British Fantasy Award; the novel went on to win the Locus Poll Award for Best Fantasy Novel
George_R._R._Martin
1973 short story by Ursula K. Le Guin
single child. "The Ones Who Walk Away from Omelas" was nominated for the Locus Award for Best Short Fiction in 1974 and won the Hugo Award for Best Short
The Ones Who Walk Away from Omelas
The_Ones_Who_Walk_Away_from_Omelas
Medical condition
Evidence for this locus was also found using a transmission disequilibrium test (TDT) in 12 Bavarian families. The second RLS locus maps to chromosome
Restless_legs_syndrome
Measurement of genetic variations
types of genetic variation. An SNP is a single base pair mutation at a specific locus, usually consisting of two alleles (where the rare allele frequency
SNP_genotyping
Cross between two organisms with different variations at one genetic locus of interest
a cross between two organisms with different variations at one genetic locus of interest. The character(s) being studied in a monohybrid cross are governed
Monohybrid_cross
Rules a court uses to choose the law under which a case will be decided
patents. It stipulates that the law applied to such cases is the law of the locus protectionis, that is, the law of the country for which legal protection
Lex_loci
Autoimmune disease
glands. Diagnosis is by biopsy of moisture-producing glands and blood tests for specific antibodies. On biopsy there are typically lymphocytes within the glands
Sjögren's_disease
Technique used to identify individuals via DNA characteristics
enforcement officials to test DNA samples from crimes for matches within the database, providing a means of finding specific biological profiles associated
DNA_profiling
Indirect selection process in breeding
organism Testing for the marker does not have variable success depending on the allele at the marker locus or the allele at the target locus (the gene
Marker-assisted_selection
Process in genetics
epistatic effect. Epistasis is the event when one allele at a locus prevents an allele at another locus to express its product as if it is masking its effect
Transgressive_segregation
Sex-specific cell surface antigen in mammals
H-Y antigen is a male tissue specific antigen. Originally thought to trigger the formation of testes (via loci, an autosomal gene that generates the antigen
H-Y_antigen
Hair coat color of horses
the agouti locus. One genetics lab offered a test for seal brown in 2009, but the underlying studies were not peer-reviewed and the test was pulled from
Seal_brown_(horse)
Distortion to enhance self-esteem, or to see oneself overly favorably
(i.e. self-enhancement, self-presentation) and cognitive processes (i.e. locus of control, self-esteem) influence the self-serving bias. There are both
Self-serving_bias
Inherited neurodegenerative disorder
be made following the appearance of physical symptoms specific to the disease. Genetic testing can be used to confirm a physical diagnosis if no family
Huntington's_disease
Family of genetic disorders caused by missing genes in the Y chromosome
genetic testing techniques for the Y chromosome are developed.[citation needed] Much study has been focused upon the "azoospermia factor locus" (AZF),
Y_chromosome_microdeletion
American personal genomics company
health-related tests, which were suspended in the US from late 2013 until October 2015, when the FDA began granting approvals for specific carrier status
23andMe
Medical condition
via the following methods/tests: Thyroid function test Liver function test Cellular immunity test Skin biopsy Genetic testing Management for an individual
Chronic mucocutaneous candidiasis
Chronic_mucocutaneous_candidiasis
Neurological movement disorder
Ferraris A, et al. (March 2001). "DYT13, a novel primary torsion dystonia locus, maps to chromosome 1p36.13--36.32 in an Italian family with cranial-cervical
Dystonia
Color image encoding system
source". The system defines its own primary colors as being on the spectral locus as defined by the CIE xyY specification. The white point is approximate
Academy_Color_Encoding_System
Identification of genetic markers through phenotype-based analysis
the mutation. A consistent difference on a locus between the two bulked samples likely means that the locus is associated with the mutation of interest
Bulked_segregant_analysis
Color space defined by the CIE in 1931
color space formed by the primaries, which never touches the monochromatic locus nor the purple line except at the three primaries. In other words, there
CIE_1931_color_space
Test for genetic linkage between a marker and trait
a genetic marker and a trait. It is an application of McNemar's test. A specificity of the TDT is that it will detect genetic linkage only in the presence
Transmission disequilibrium test
Transmission_disequilibrium_test
Group of genetic connective tissues disorders
ten types, some of the specific variations involved have been identified, and they can be precisely identified by genetic testing; this is valuable due
Ehlers–Danlos_syndrome
Agricultural raising and breeding of rabbits
Zealand White is one of the most commonly used breeds for research and testing. Specific strains of the New Zealand White have been developed, with differing
Cuniculture
Personality model consisting of five broad dimensions
Tansu; Balbag, Zafer; Cemrek, Fatih (2010-01-01). "The role of self-esteem, locus of control and big five personality traits in predicting hopelessness".
Big_Five_personality_traits
Individuals nearly identical in genotype due to long inbreeding
genes with a UAS sequence specific to Gal4, which are not normally found in Drosophila, meaning that a researcher can test the expression of a transgenic
Inbred_strain
Genetic testing technique
are specific to a particular region (locus) of DNA; these mixtures are used to detect deletion mutations. When combined with a specific color, a locus-specific
Fluorescence in situ hybridization
Fluorescence_in_situ_hybridization
1985 novel by Orson Scott Card
July 31, 2008. Retrieved January 3, 2009. "The Locus Index to SF Awards: About the Hugo Awards". Locus Publications. Archived from the original on January
Ender's_Game
Inability to digest lactose
are both located on the long arm (q) of chromosome 2 in region 21. The locus can be expressed as 2q21. The lactase deficiency also could be linked to
Lactose_intolerance
Transient loss of consciousness and postural tone
in those with pulmonary embolism. More specific tests such as implantable loop recorders, tilt table testing or carotid sinus massage may be useful in
Syncope_(medicine)
Forming something new and somehow valuable
research on the locus coeruleus system. It describes how decision-making processes studied by neuroeconomists as well as activity in the locus coeruleus system
Creativity
Neurological condition involving the crossing of senses
for synesthesia. Each common type has a specific test. When testing for grapheme–color synesthesia, a visual test is given. The person is shown a picture
Synesthesia
Classification of blood types
alleles at one locus in 1924. Watkins and Morgan, in England, discovered that the ABO epitopes were conferred by sugars, to be specific, N-acetylgalactosamine
ABO_blood_group_system
Process by which individuals explain causes of behavior and events
motivate an individual in specific tasks by increasing levels of autonomy, relatedness, and competence. The theory of perceived locus of causality lead to
Attribution_(psychology)
Dog breed
being affected by the disease. A genetic test is available for this disease. For the Samoyeds several breed-specific hereditary diseases are described in
Samoyed_dog
Family of inherited blood disorders
blood tests including a complete blood count, special hemoglobin tests, and genetic tests. Diagnosis may occur before birth through prenatal testing. Treatment
Thalassemia
Type of genetic selection favoring one extreme phenotype
PMID 12221290. Orr, H.A. (1998). "Testing Natural Selection vs. Genetic Drift in Phenotypic Evolution Using Quantitative Trait Locus Data". Genetics. 149 (4):
Directional_selection
Aggressive type of brain cancer
modulation in glioblastoma 14. TMZR1-eRNA, an eRNA transcribed from the STAT3 locus, directly regulates STAT3 expression, a key driver of temozolomide (TMZ)
Glioblastoma
Bias confirming existing attitudes
screen followed specific laws, which the participants had to figure out. So, participants could "fire" objects across the screen to test their hypotheses
Confirmation_bias
Single stranded RNA
years the idea of targeting asRNAs to increase gene expression in a locus specific manner has been drawing much attention. Due to the nature of drug development
Antisense_RNA
Term of cognitive psychology
the Matching Familiar Figures Test (MFFT) developed by Jerome Kagan in 1964. The MFFT asks individuals to find a specific item that exactly matches what
Cognitive_tempo
Genetics behind the equine coat color
chestnut. A change at the agouti locus is capable of turning bay to black, while a mutation at the extension locus can turn bay or black to chestnut
Equine_coat_color_genetics
Branch of psychology focused on personality
and to global or specific causes. Various scales have been developed to assess both attributional style and locus of control. Locus of control scales
Personality_psychology
Class of enzymes
CELA1 (synonym: ELA1) Pancreatic elastase 1 is encoded by a single genetic locus on chromosome 12. Studies of human pancreatic elastase 1 have shown that
Pancreatic_elastase
Disorder in which muscles fail to relax
Harper PS, Shaw DJ (May 1991). "Localisation of the myotonic dystrophy locus to 19q13.2-19q13.3 and its relationship to twelve polymorphic loci on 19q"
Myotonic_dystrophy
Gene responsible for color variations in many species
horses (Equus caballus). This study used a DNA test to identify the recessive a allele on the Agouti locus, and found that none of the horses fitting the
Agouti_coloration_genetics
Brief interruptions of sleep
the time of testing, and the specific type of task performed. Research has suggested that fluctuations in noradrenaline released by the locus coeruleus
Microarousal
Basic unit of taxonomic classification, below genus
single locus which is simple enough for non-specialists to apply and, in most cases, sufficient to distinguish species. Using a single easy-to-use locus to
Species
Developmental or acquired neurological disorders
to standardized tests that are visual analogs of auditory tests. The debate over this issue remains unresolved between modality-specific researchers such
Auditory_processing_disorder
Human chromosome
The Se locus is located on chromosome 19 at 19q13.3. It contains two exons that span about 25 kb of genomic DNA. The Se locus encodes a specific fucosyltransferase
Chromosome_19
Subclass of HLA-D antigens that consist of alpha and beta chains
HLA-DRB3 locus encodes the HLA-DR52 specificity, is moderately variable and is variably associated with certain HLA-DRB1 types. The HLA-DRB4 locus encodes
HLA-DR
Protein(s) forming a major part of an organism's immune system
initial proof of concept in a small specific patient population (in vitro or in vivo testing).[citation needed] Testing cross-reactivity of antibody: to
Antibody
Breed of domestic cat
wide band locus, and the responsible allele is only found in the Siberian breed. The two other identified alleles on this wide band locus are responsible
Siberian_cat
Type of dilution gene
gene, also known as the "Barlink factor", is a dilution gene at the same locus as the cream gene, which somewhat resembles the cream gene and the champagne
Pearl_gene
2024 video game
giant man named Locus breaks into the College, steals a cat mummy, and knocks Jones unconscious before leaving. Jones notices Locus's medallion bears
Indiana Jones and the Great Circle
Indiana_Jones_and_the_Great_Circle
Species of bacterium
basis for P. aeruginosa resistance to antibiotics such as tobramycin. One locus identified as being an important genetic determinant of the resistance in
Pseudomonas_aeruginosa
Disorder of decreased tolerance to specific sounds
selective sound sensitivity syndrome) is a disorder of decreased tolerance to specific sounds or their associated stimuli, or cues. These cues, known as "triggers"
Misophonia
SPECIFIC LOCUS-TEST
SPECIFIC LOCUS-TEST
Girl/Female
Australian, Chinese, Dutch, Vietnamese
Lotus Flower; Lotus
Girl/Female
Tamil
Mrinalika | மரநாலிகா
Lotus stalk, Lotus stem, Lotus
Mrinalika | மரநாலிகா
Girl/Female
African, Australian, Christian, Danish, Greek
Dreamlike; Lotus Flower
Girl/Female
Hindu
Lotus stalk, Lotus stem, Lotus
Girl/Female
Hindu
Lotus stalk, Lotus stem, Lotus
Girl/Female
Tamil
Lotus stalk, Lotus stem, Lotus
Boy/Male
Tamil
Pankajam | பநà¯à®•à®¾à®œà®®
Lotus
Pankajam | பநà¯à®•à®¾à®œà®®
Boy/Male
Tamil
Hayagriv | ஹயாகà¯à®°à®¿à®µ
One of krishnas incarnations. specific to education
Hayagriv | ஹயாகà¯à®°à®¿à®µ
Boy/Male
Indian, Sanskrit
Calmed; Pacific Sea
Girl/Female
Arabic
Precious; Lord of Specific Wood
Female
English
English name derived from the flower name, from Latin lotus, from Greek lotos, a name for various kinds of plants before it came to designate the Egyptian "white lotus." The Greek word may ultimately come from Hebrew lowt, LOTUS means "covering, veil."
Girl/Female
Gujarati, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Sindhi, Tamil, Telugu
Focus; Test
Boy/Male
Tamil
Lotus
Boy/Male
Latin
Friend of Hercules.
Girl/Female
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Telugu, Traditional
Lotus Eyes; Lotus Eyed
Girl/Female
Hindu, Indian, Malayalam, Marathi, Sanskrit, Sikh, Tamil
Aim; Destination; Who has a Specific Goal Everywhere; Target
Girl/Female
American, Australian, Christian, Nigerian
Flaxen; Pacific Islander
Boy/Male
Hindu
One of krishnas incarnations. specific to education
Girl/Female
Greek Egyptian
Flower.
Boy/Male
Latin
Friend of Hercules.
SPECIFIC LOCUS-TEST
SPECIFIC LOCUS-TEST
Girl/Female
Arabic
World of Making
Girl/Female
Indian
God's Gift
Boy/Male
Indian, Sanskrit
Energy; Vigour; Strength
Surname or Lastname
English
English : variant of Wimbish.
Boy/Male
Teutonic English
From the north.
Male
Greek
(ΤÏχων) Greek name TYCHON means "hitting the mark."
Boy/Male
Tamil
Pruthuraaj | பரதà¯à®°à®¾à®œ
Boy/Male
Anglo, British, English
Valued
Male
African
born on Tuesday.
Male
Hebrew
(סָבָ×) Hebrew unisex name SABA means "aged, old." Compare with another form of Saba.
SPECIFIC LOCUS-TEST
SPECIFIC LOCUS-TEST
SPECIFIC LOCUS-TEST
SPECIFIC LOCUS-TEST
SPECIFIC LOCUS-TEST
pl.
of Locus
a.
Specifying; definite, or making definite; limited; precise; discriminating; as, a specific statement.
n.
The lotus of the lotuseaters, probably a tree found in Northern Africa, Sicily, Portugal, and Spain (Zizyphus Lotus), the fruit of which is mildly sweet. It was fabled by the ancients to make strangers who ate of it forget their native country, or lose all desire to return to it.
n.
A point so related to a conic section and certain straight line called the directrix that the ratio of the distace between any point of the curve and the focus to the distance of the same point from the directrix is constant.
a.
Anything having peculiar adaption to the purpose to which it is applied.
v. t.
To mention or name, as a particular thing; to designate in words so as to distinguish from other things; as, to specify the uses of a plant; to specify articles purchased.
n.
A place; a locality.
n.
A specific remedy. See Specific, a., 3.
n.
The line traced by a point which varies its position according to some determinate law; the surface described by a point or line that moves according to a given law.
n.
The locust tree. See Locust Tree (definition, note, and phrases).
a.
Of or pertaining to peace; suited to make or restore peace; of a peaceful character; not warlike; not quarrelsome; conciliatory; as, pacific words or acts; a pacific nature or condition.
a.
Exerting a peculiar influence over any part of the body; preventing or curing disease by a peculiar adaption, and not on general principles; as, quinine is a specific medicine in cases of malaria.
n.
A point in which the rays of light meet, after being reflected or refrcted, and at which the image is formed; as, the focus of a lens or mirror.
imp. & p. p.
of Specify
n.
A genus (Lotus) of leguminous plants much resembling clover.
pl.
of Locus
n.
A name of several kinds of water lilies; as Nelumbium speciosum, used in religious ceremonies, anciently in Egypt, and to this day in Asia; Nelumbium luteum, the American lotus; and Nymphaea Lotus and N. caerulea, the respectively white-flowered and blue-flowered lotus of modern Egypt, which, with Nelumbium speciosum, are figured on its ancient monuments.
v. t.
To bring to a focus; to focalize; as, to focus a camera.
a.
Specific.
a.
Of or pertaining to a species; characterizing or constituting a species; possessing the peculiar property or properties of a thing which constitute its species, and distinguish it from other things; as, the specific form of an animal or a plant; the specific qualities of a drug; the specific distinction between virtue and vice.