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Abnormal stiffness of skeletal muscle
inhibitory actions contribute to baclofen's efficacy as an anti-spasticity agent. Spasticity is usually caused by damage to nerve pathways within the brain
Spasticity
American heavy metal band
Metallica is an American heavy metal band. It was formed in Los Angeles in 1981 by vocalist/guitarist James Hetfield and drummer Lars Ulrich, and has been
Metallica
Topics referred to by the same term
Spastic can refer to: Spasticity, a feature of altered muscle performance A historical reference to people with the movement disorders, see cerebral palsy
Spastic
Medical condition
Spastic hemiplegia is a neuromuscular condition of spasticity that results in the muscles on one side of the body being in a constant state of contraction
Spastic_hemiplegia
Group of genetic disorders affecting motor neurons controlling the lower limbs
progressive stiffness (spasticity) and contraction in the lower limbs. HSP is also known as hereditary spastic paraparesis, familial spastic paraplegia, French
Hereditary_spastic_paraplegia
Form of cerebral palsy affecting the lower body muscles
Less often, spasticity is severe enough to compel the person to use a wheelchair. In general, however, lower-extremity spasticity in spastic diplegia is
Spastic_diplegia
Cerebral palsy characterized by high muscle tone
Spastic cerebral palsy is the type of cerebral palsy characterized by spasticity or high muscle tone often resulting in stiff, jerky movements. Cases of
Spastic_cerebral_palsy
Word
In medicine, the adjective spastic refers to an alteration in muscle tone affected by the medical condition spasticity, which is a well-known symptomatic
Spastic_(word)
Paralysis of all four limbs and torso
hypertonicity/spasticity, contractures, painful hyperesthesias and paralyzed proximal upper limb muscles with distal muscle sparing. Spasticity is a frequent
Tetraplegia
Muscle relaxant medication
relaxant which is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. Its effectiveness appears
Tizanidine
Gait abnormality
Spastic gait is a form of gait abnormality. It is caused by lesions in the corticospinal tract. A unilateral spastic gait presents with the affected leg
Spastic_gait
Abnormal increase in muscle tone due to nerve damage
interval" is appreciated in spasticity but not in rigidity because the resting muscle is electromyographically silent in spasticity. In contrast, in rigidity
Hypertonia
Functional gastrointestinal disorder
Irritable bowel syndrome Other names Spastic colon, nervous colon, mucous colitis, spastic bowel 3D depiction of the pain of IBS Specialty Gastroenterology
Irritable_bowel_syndrome
Medical condition
mental retardation and spasticity - OMIM". omim.org. Retrieved 2022-07-12. Jancar, J. (2008-06-28). "Ectrodactyly, spasticity and mental retardation"
Intellectual disability-spasticity-ectrodactyly syndrome
Intellectual_disability-spasticity-ectrodactyly_syndrome
Indian disability rights organization
ADAPT – Able Disabled All People Together (formerly known as The Spastics Society of India) is an Indian non-profit and non-governmental organization,
Able Disabled All People Together
Able_Disabled_All_People_Together
Movement disorders that appear in early childhood
"spastic" denotes the attribute of spasticity in types of spastic CP. In 1952 a UK charity called The Spastics Society was formed. The term "spastics"
Cerebral_palsy
Set of involuntary and rhythmic muscular contractions and relaxations
outcome of spasticity. Although closely linked, clonus is not seen in all patients with spasticity. Clonus tends to not be present with spasticity in patients
Clonus
Condition in which the head is small due to an underdeveloped brain
may also occur. Motor ability varies, ranging from clumsiness in some to spastic quadriplegia in others. Microcephaly is a type of cephalic disorder. It
Microcephaly
Neurotoxin produced by Clostridium botulinum
muscle movement, including cerebral palsy, post-stroke spasticity, post-spinal cord injury spasticity, spasms of the head and neck, eyelid, vagina, limbs
Botulinum_toxin
Neurosurgical procedure performed on the spinal cord
(severe spasticity). Abnormal nerve responses (usually graded a 3 or 4) are isolated and cut, thereby reducing symptoms of spasticity. Spasticity is defined
Selective_dorsal_rhizotomy
Neurological disorder
limbs (both arms and legs). Compared to quadriplegia, spastic tetraplegia is defined by spasticity of the limbs as opposed to strict paralysis. It is distinguishable
Spastic_quadriplegia
UK disability charity
for people with cerebral palsy (commonly referred to as spastics at the time, despite spasticity being a symptom of only one variant of cerebral palsy)
Scope_(charity)
Degeneration of the upper motor neurons, causing muscle weakness
and stiffness in the legs, and clumsiness. Other common symptoms are spasticity (involuntary muscle contraction due to the stretching of muscle, which
Primary_lateral_sclerosis
Medical condition
People with spastic paraplegia 6 generally start showing symptoms during their late teenage years or early adulthood, the symptoms are spasticity affecting
Spastic_paraplegia_6
Motor-control abnormalities resulting from an upper motor neuron lesion
into positive and negative signs. Positive signs include hyperreflexia, spasticity, involuntary muscle spasms, and clonus. Negative signs include reduced
Upper_motor_neuron_syndrome
or diplegic spasticity; severe athetosis or ataxia; bilateral through knee amputation, etc. C2: moderate hemiplegic or diplegic spasticity; moderate athetosis
Cycling at the 2024 Summer Paralympics – Men's road race C1–3
Cycling_at_the_2024_Summer_Paralympics_–_Men's_road_race_C1–3
Muscle relaxant medication
found that in certain people, spasticity decreased. In 1971, it was introduced as a treatment for certain form of spasticity. It was approved by the US Food
Baclofen
or diplegic spasticity; severe athetosis or ataxia; bilateral through knee amputation, etc. C2: moderate hemiplegic or diplegic spasticity; moderate athetosis
Cycling at the 2024 Summer Paralympics – Women's road time trial C1–3
Cycling_at_the_2024_Summer_Paralympics_–_Women's_road_time_trial_C1–3
Involuntary contraction of a muscle, organ or orifice
can also cause spasms and cramp. Spasms can occur in dystonia, and in spasticity. A spasm may lead to muscle strains or tears in tendons and ligaments
Spasm
Specific cannabis extract
reduction of spasticity. A systematic review in 2014 by the American Academy of Neurology found that nabiximols was 'probably effective' for spasticity, pain
Nabiximols
Impairment of motor and sensory functions in the lower limbs
affected, the correct term is monoplegia. Spastic paraplegia is a form of paraplegia defined by spasticity of the affected muscles, rather than flaccid
Paraplegia
diplegic spasticity; mild athetosis or ataxia; unilateral below knee or bilateral below elbow amputation, etc. C5: mild monoplegic spasticity; unilateral
Cycling at the 2024 Summer Paralympics – Women's road race C4–5
Cycling_at_the_2024_Summer_Paralympics_–_Women's_road_race_C4–5
Rare neurodegenerative disease
commonly used oral drugs for treating spasticity; an intrathecal baclofen pump can be used for severe spasticity, and mexiletine is safe and effective
ALS
Psychoactive component of cannabis
effective for treating spasticity and chronic pain, but caused numerous short-lasting adverse events, such as dizziness. Spasticity. Based on the results
Tetrahydrocannabinol
diplegic spasticity; severe athetosis or ataxia; bilateral through knee amputation, etcetera. C2: cyclists with moderate hemiplegic or diplegic spasticity; moderate
Cycling at the 2024 Summer Paralympics – Women's road race C1–3
Cycling_at_the_2024_Summer_Paralympics_–_Women's_road_race_C1–3
Permanent shortening of a muscle or joint
same time that tendency toward spasticity is addressed. Contractures can have a variety of causes other than spasticity. In regards to muscle, these include
Contracture
Pediatric neurologist, scientist and department chair
at Children’s Hospital of New Orleans, director of the Comprehensive Spasticity Program, and co-director of the Muscular Dystrophy clinics. The textbook
Ann_Tilton
Medical condition
only accounts for 3 to 9% of ADSPG diagnosis in the world. Spasticity Hereditary spastic paraplegia Hereditary sensory and autonomic neuropathy RESERVED
Spastic_paraplegia_31
American progressive metal band
Spastic Ink was an American progressive metal band. Spastic Ink was formed in 1993 by guitarist Ron Jarzombek of Watchtower after recovering from multiple
Spastic_Ink
Pharmaceutical compound
inhibitor which is under development for the treatment of agitation, muscle spasticity, and neurological disorders. It is taken orally. The drug is an irreversible
Irafamdastat
Class of medications
featuring spasticity in neurologic conditions such as cerebral palsy, multiple sclerosis, and spinal cord disease. Medications are commonly used for spastic movement
Antispasmodic
Congenital disease of cattle by permanent stretching of gastrocnemius muscle
Spastic paresis is a congenital disorder of cattle. It is due to contraction of gastrocnemius muscle, which develops within the first 6 months of life
Spastic_paresis_(cattle)
Neurological signs and symptoms
typically lack of orgasm, probably related to disordered genital sensation. Spasticity is characterised by involuntary muscle movements (spasms), muscle stiffness
Signs and symptoms of multiple sclerosis
Signs_and_symptoms_of_multiple_sclerosis
Indian actress and producer (born 1981)
Mirza has been involved with the Cancer Patients Aid Association and Spastics Society of India, and has worked extensively with the government of Andhra
Dia_Mirza
Continuous and passive partial contraction of the muscles
extrapyramidal tract. Hypertonia can present clinically as either spasticity or rigidity. While spasticity is velocity-dependent resistance to passive stretch (e
Muscle_tone
American actress (born 1970)
believe that such a creature could exist—an exquisite-looking woman so spastic and needy that she repulses regular Joes. Thurman has bent the role to
Uma_Thurman
Drug for skeletal muscle function
are used to alleviate musculoskeletal pain and spasms and to reduce spasticity in a variety of neurological conditions. While both neuromuscular blockers
Muscle_relaxant
Rare genetic disorder
Hypomyelination with brainstem and spinal cord involvement and leg spasticity (HBSL) is a rare autosomal recessive disorder which is caused by a mutation
Hypomyelination with brainstem and spinal cord involvement and leg spasticity
Hypomyelination_with_brainstem_and_spinal_cord_involvement_and_leg_spasticity
Intestinal blockage caused by intestine spasms
Spastic intestinal obstruction[citation needed] is an obstruction of the intestine that causes a result closure of an intestinal segment due to intestinal
Spastic intestinal obstruction
Spastic_intestinal_obstruction
Swedish musician (born 1973)
Daniel Gildenlöw (born 5 June 1973) is a Swedish musician and songwriter. He is best known as a multi-instrumentalist and vocalist for the progressive
Daniel_Gildenlöw
American actress (1946–2025)
date on Saturday night, but has only to open her mouth or gulp or dart spastically sideways to reveal herself as the insecure bungler she is, as complete
Diane_Keaton
diplegic spasticity; mild athetosis or ataxia; unilateral below knee or bilateral below elbow amputation, etc. C5: mild monoplegic spasticity; unilateral
Cycling at the 2024 Summer Paralympics – Men's road race C4–5
Cycling_at_the_2024_Summer_Paralympics_–_Men's_road_race_C4–5
Medical condition
and τόνος, tonos, 'tension') is a state of severe hyperextension and spasticity in which an individual's head, neck and spinal column enter into a complete
Opisthotonus
Group of neurodegenerative disorders
hypotonia, spasticity, and variable visual defects PCH9 615809 AMPD2 1p13.3 Severely delayed psychomotor development, progressive microcephaly, spasticity, seizures
Pontocerebellar_hypoplasia
Human spinal cord disorder
neuron corticospinal tract produces ipsilateral spastic paralysis below the level of the lesion. Spasticity is a consequence of disruption of ipsilateral
Brown-Séquard_syndrome
Approach to recover from hemiplegia after a stroke
synergies Increase in spasticity Some movement patterns out of synergy are mastered (synergy patterns still predominate) Decrease in spasticity If progress continues
Brunnstrom_Approach
Medical condition
Hereditary motor and sensory neuropathies (HMSN) is a name sometimes given to a group of different neuropathies which are all characterized by their impact
Hereditary motor and sensory neuropathy
Hereditary_motor_and_sensory_neuropathy
Medical condition
paucity of voluntary and involuntary movements, unrelated to weakness or spasticity. Movement disorders are conventionally divided into two major categories-
Movement_disorder
Rare genetic disorder
spine (opisthotonus). Signs of pyramidal system involvement, including spasticity, overactive reflexes (hyperreflexia) and extensor plantar reflexes, also
Lesch–Nyhan_syndrome
1976 studio album by Funkadelic
Tales of Kidd Funkadelic is the eighth studio album by the band Funkadelic, released in September 1976. It was their final album on the Westbound record
Tales_of_Kidd_Funkadelic
English surgeon
first medical identification of spastic diplegia, when he observed it in the 1860s amongst children. While spasticity surely existed before that point
William_John_Little
Protein-coding gene in the species Homo sapiens
hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy
AFG3L2
Australian nonprofit organisation
Cerebral Palsy Alliance (formerly The Spastic Centre) is an Australian nonprofit organisation helping babies, children, teenagers and adults living with
Cerebral_Palsy_Alliance
Chemical compound
also used in the management of neuroleptic malignant syndrome, muscle spasticity (e.g. after strokes, in paraplegia, cerebral palsy, or patients with multiple
Dantrolene
Genetic disorder
in adulthood. Hereditary spastic paraplegia (HSP) type 15 is characterised by slowly progressive muscle stiffness (spasticity) and paralysis (paraplegia)
SPG15_(disease)
Permanent shortening of a muscle
has a disability that causes spasticity (such as cerebral palsy), they may walk on their toes involuntarily. If spasticity is left untreated, contractures
Muscle_contracture
Loss of sensation and paralysis following a spinal cord injury
Denervation supersensitivity 3 1–4w Hyperreflexia (initial) Axon-supported synapse growth 4 1–12m Hyperreflexia, Spasticity Soma-supported synapse growth
Spinal_shock
Medical condition
Tropical spastic paraparesis (TSP) is a medical condition that causes weakness, muscle spasms, and sensory disturbance by human T-lymphotropic virus resulting
Tropical_spastic_paraparesis
Para-swimming classification
The spasticity athetosis level and location of a CP7 sportsperson.
S7_(classification)
Rare genetic disorder
delay. While some patients may be able to walk, others may not due to spasticity of limbs and hypotonic muscle tone, with progressive degeneration over
SPATCCM
Branch of medicine
cord injury, brain injury, musculoskeletal injury, stroke, pain, and spasticity from muscle, ligament, or nerve damage. PM&R physicians lead rehabilitation
Physical medicine and rehabilitation
Physical_medicine_and_rehabilitation
or diplegic spasticity; severe athetosis or ataxia; bilateral through knee amputation, etc. C2: moderate hemiplegic or diplegic spasticity; moderate athetosis
Cycling at the 2024 Summer Paralympics – Men's time trial C1–3
Cycling_at_the_2024_Summer_Paralympics_–_Men's_time_trial_C1–3
Medical diagnostic method
during passive soft-tissue stretching and is used as a simple measure of spasticity. Scoring (taken from Bohannon and Smith, 1987): 0: No increase in muscle
Modified_Ashworth_scale
Autism associated with another medical condition
study composed by 9 male participants] Clinically defined Brachycephaly, spasticity, recurrent respiratory infections, gastrointestinal hypermotility, genitourinary
Syndromic_autism
Written by Original release date Prod. code U.S. viewers (millions) 13 1 "Spasticity" Constantine Makris Andrew Lenchewski June 3, 2010 (2010-06-03) RP#201
List_of_Royal_Pains_episodes
cause unnecessary complications. Spasticity is measured with the Ashworth scale. Occupational therapy targeting spasticity aims to lengthen the overactive
Management_of_cerebral_palsy
Region of the cerebral cortex involved in voluntary movement
corticospinal fibers in the medullary pyramids. Upper motor neuron signs (spasticity, hyperreflexia, Babinski sign) reflect corticospinal and cortical dysfunction
Motor_cortex
Abnormal increase in cerebrospinal fluid in the ventricles of the brain
(urinary incontinence) Loss of coordination and trouble walking Muscle spasticity (spasm) Slow growth (child 0–5 years) Delayed milestones Failure to thrive
Hydrocephalus
Rare form of progressive brain inflammation
Specialty Neurology, infectious diseases Symptoms Behavior changes, seizures, spasticity, poor coordination, coma Usual onset 6–15 years after infection with measles
Subacute sclerosing panencephalitis
Subacute_sclerosing_panencephalitis
Medical condition
seizures, spasticity, and digestive issues. Orthotics like braces and assistive devices like standers and wheel chairs can improve bone health, spasticity, and
Warburg_Micro_syndrome
Antispasmodic and muscle relaxant drug
ischaemia, and hypertonia in skeletal muscles, thus alleviating stiffness and spasticity, and facilitating muscle movement Eperisone also improves dizziness and
Eperisone
Muscle relaxant medication
long-term. It is the best-studied muscle relaxer. It is not useful for spasticity due to neurologic conditions such as cerebral palsy. It may also be used
Cyclobenzaprine
This is a list of schools in North Tyneside, Tyne and Wear, England. Amberely Primary School, Killingworth Appletree Gardens First School, Monkseaton Backworth
List of schools in North Tyneside
List_of_schools_in_North_Tyneside
Medical condition
HSAS) this spasticity is presented as spastic paraplegia, where the muscles of the lower limbs are stiff and continuously contracted. This spastic paraplegia
L1_syndrome
Aspect of medical care
contractions), exaggerated deep tendon reflexes, spasticity and decreased endurance. The term "spasticity" is often erroneously used interchangeably with
Stroke_recovery
Autoimmune disease
MS. Symptoms that can be treated include sleep issues, pain, fatigue, spasticity (e.g. spasms or stiffness), deconditioning, sexual dysfunction and bladder
Multiple_sclerosis
Intermittent spasming of the vocal cords leading to irregular speech
the arm and mouth. This disorder was termed "Spastic Dysphonia", and as it was not a disorder with spasticity, was renamed to what is now called, "Spasmodic
Spasmodic_dysphonia
Species of virus
adult T-cell lymphoma (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), both of which are only diagnosed in individuals
Human_T-lymphotropic_virus_1
Cerebral palsy sports classification
27 This class is for the minimally affected diplegic Spasticity Grade 1; hemiplegic Spasticity Grade 1: monoplegic; minimal athetoid/ataxic athlete.
CP8_(classification)
scosa (the Spastic Centres of South Australia Inc.) was a South Australian organisation providing a range of supports to children and adults with disabilities
Scosa
Medical condition
usually progress to developmental delay, microcephaly, blindness, and spasticity. Females with residual pyruvate dehydrogenase activity will have no uncontrollable
Pyruvate dehydrogenase deficiency
Pyruvate_dehydrogenase_deficiency
Lebanese neurosurgeon and academic
focused on intrathecal baclofen infusion techniques for the treatment of spasticity. He completed his neurosurgical residency at the Hospital Universitario
Youssef_Fares_(neurosurgeon)
Type of cerebral palsy associated with basal ganglia damage
surgery. Before using oral drugs, it is important to differentiate between spasticity, dystonia, and choreoathetosis since each motor disorder has a specific
Dyskinetic_cerebral_palsy
Enzyme found in humans
dysfunction, called neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities (NEDCASB). GRCh38: Ensembl release 89: ENSG00000182199
Serine hydroxymethyltransferase 2
Serine_hydroxymethyltransferase_2
American actor and comedian
"Chuck Versus the Final Exam" 2010 Royal Pains Spencer Fisher Episode: "Spasticity" 2010 Romantically Challenged Perry Gill Main role; 6 episodes 2010–11
Kyle_Bornheimer
Medical condition
deformities ataxic dysarthria distal muscle wasting horizontal gaze nystagmus spasticity The inheritance pattern is autosomal recessive. The disorder is caused
Autosomal recessive spastic ataxia of Charlevoix-Saguenay
Autosomal_recessive_spastic_ataxia_of_Charlevoix-Saguenay
Chemical compound
was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013, XenoPort announced the
Arbaclofen_placarbil
Medical condition
proprioception (joint sense). Lateral corticospinal tract dysfunction produces spasticity and dorsal spinocerebellar tract dysfunction causes ataxia.[citation needed]
Subacute combined degeneration of spinal cord
Subacute_combined_degeneration_of_spinal_cord
Disease
paralytic abasia: caused by paralysis of the leg muscles spastic abasia: caused by spastic stiffening of the leg muscles trembling abasia: caused by
Abasia
Anticonvulsant medication
with estrogen more effectively prevents hot flashes. Gabapentin reduces spasticity in multiple sclerosis and is prescribed as one of the first-line options
Gabapentin
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