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Protein-coding gene in the species Homo sapiens
transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene. The protein encoded by this gene is a member of the SWI/SNF family
SMARCA2
Medical condition
is a rare genetic condition caused by de novo missense mutations in the SMARCA2 gene and has only been reported in fewer than 330 cases worldwide. NCBRS
Nicolaides–Baraitser_syndrome
Medical condition
mutations associated to this syndrome, including SOX11, ARID2, DPF2, PHF6, SMARCA2, SMARCA4, SMARCB1, SMARCC2, SMARCE1, SOX4. The diagnosis is generally based
Coffin–Siris_syndrome
Chromatin remodeling complex
ATP hydrolysis mediated by its catalytic subunits BRG1 (SMARCA4) or BRM (SMARCA2). The BAF complex exists in three subtypes, canonical BAF (cBAF), polybromo-associated
Mammalian SWI/SNF (BAF) complex
Mammalian_SWI/SNF_(BAF)_complex
Subfamily of ATP-dependent chromatin remodeling complexes
(2018-11-21). "Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant
SWI/SNF
Pharmaceutical compound
of cancer. It is a small molecule that acts as a selective inhibitor of SMARCA2 and SMARCA4, which are key components of the SWI/SNF chromatin remodeling
Camibirstat
Protein-coding gene in humans
HMGA1, HSF1, Nucleolar phosphoprotein p130, RELA, Serum response factor, SMARCA2, Sp1 transcription factor, TRIM28, and Zif268. Ccaat-enhancer-binding proteins
CEBPB
Protein-coding gene in the species Homo sapiens
Cyclin-dependent kinase 8, Myc, P53, POLR2A, PPP1CA, PPP1CB, PPP1CC, PPP1R15A, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SS18, and XPO1. ENSG00000275837 GRCh38: Ensembl
SMARCB1
Protein-coding gene in the species Homo sapiens
GTF2F1, GTF2H4, MED21, MED26, PCAF, POLR2C, POLR2E, POLR2H, POLR2L, PQBP1, SMARCA2, SMARCA4 SMARCB1, SMYD3, SND1, SUPT5H, TAF11, TBP, TCEA1, TCERG1, and ZNF74
POLR2A
Protein-coding gene in humans
tumor suppressor gene. ARID1B has been shown to interact with SMARCA4 and SMARCA2. GRCh38: Ensembl release 89: ENSG00000049618 – Ensembl, May 2017 GRCm38:
ARID1B
Mammalian protein found in Homo sapiens
shown to interact with: ANXA2 C-Raf, E2F1, HDAC1, P53, RB1, RBL1, RBL2, SMARCA2, and SMARCA4. Aurilide Fluorizoline Rocaglamide A Prohibitinn in insect
Prohibitin
Protein-coding gene in the species Homo sapiens
factors. SMARCC1 has been shown to interact with: BAZ1B, ING1, SIN3A, SMARCA2, SMARCA4, and SMARCB1. GRCh38: Ensembl release 89: ENSG00000173473 – Ensembl
SMARCC1
Sub-field of genomics
essential-genes in process other than metabolism, namely the SMARCA4 and SMARCA2 subunits in the chromatin-remodeling SWI/SNF complex. Some oncogenes are
Oncogenomics
Zinc Finger 821
domain-containing protein 85B Two Hybrid Pooling Transcriptional Repressor SMARCA2 Probable global transcription activator SNF2L2 Two Hybrid Pooling Transcriptional
ZNF821
Protein-coding gene in the species Homo sapiens
synovial sarcoma. SS18 has been shown to interact with: EP300, MLLT10, SMARCA2, and SMARCB1. GRCh38: Ensembl release 89: ENSG00000141380 – Ensembl, May
SS18
Protein-coding gene in the species Homo sapiens
carcinomas, it promotes metastasis. ACTL6A has been shown to interact with SMARCA2, Myc, Transformation/transcription domain-associated protein, RuvB-like
ACTL6A
15299 SMAP2 HGNC:25082; Q8WU79 15300 SMARCA1 HGNC:11097; P28370 15301 SMARCA2 HGNC:11098; P51531 15302 SMARCA4 HGNC:11100; P51532 15303 SMARCA5 HGNC:11101;
List of human protein-coding genes 7
List_of_human_protein-coding_genes_7
Proteins that help regulate transcription
SWI/SNF family chromatin structure remodeling complex ISWI protein SMARCA1, SMARCA2 Coactivator (genetics) Corepressor (genetics) Nuclear receptor coregulators
Transcription_coregulator
American biologist
Ho J, Sharp A, Shokhirev MN, Hargreaves DC. Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4. Mol
Diana_Hargreaves
Protein-coding gene in the species Homo sapiens
OGT, PHF12, Promyelocytic leukemia protein, RBBP4, RBBP7, SAP130, SAP30, SMARCA2, SMARCA4, SMARCC1, SUDS3, TAL1, and Zinc finger and BTB domain-containing
SIN3A
SMARCA2
SMARCA2
SMARCA2
SMARCA2
Girl/Female
Indian, Sikh
Beautiful
Surname or Lastname
English
English : topographic name for someone who lived ‘at the gate’, i.e. one of the gates of a medieval city. However, in northern counties, Middle English gate (from Old Norse gata) also meant ‘street’, and in some instances the surname may derive from this sense.Southern Italian : from the Greek personal name Agathē meaning ‘virtuous’, ‘honest’.Indian (Maharashtra); pronounced as ag-tay : Hindu (Brahman) name, from Marathi ag̣te ‘live coal’ (from Sanskrit agni ‘fire’).Thomas Agate, a native of Shipley in Yorkshire, settled in Sparta, NY, in the 1790s.
Boy/Male
Hindu, Indian
Charming
Boy/Male
Celtic Irish
Battle.
Girl/Female
Slavic
Active.
Girl/Female
Celebrity, Hindu, Indian, Mythological, Sanskrit, Tamil
The Consort of Lord Vishnu; Mahalakshmi
Boy/Male
Indian, Sanskrit
Light of the Universe
Surname or Lastname
English
English : variant of Garrett 1.French : variant of Gérard (see Gerard).
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sindhi, Telugu
Faith; Firmness; Accusatory
Girl/Female
Muslim/Islamic
Joy
SMARCA2
SMARCA2
SMARCA2
SMARCA2
SMARCA2