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First lymph node to receive drainage from a primary tumor
bodily fluids for harmful substances. The sentinel lymph node is the hypothetical first lymph node (or group of nodes) to which metastasizing cancer cells
Sentinel_lymph_node
Lymph nodes in the human armpit
The axillary lymph nodes or armpit lymph nodes are lymph nodes in the human armpit. Between 20 and 49 in number, they drain lymph vessels from the lateral
Axillary_lymph_nodes
Skin cancer originating in melanocytes
benefit. Sentinel lymph node biopsy may indicate if cancer has spread to local lymph nodes and guide treatment decisions. Neither sentinel lymph node biopsy
Melanoma
Chemical compound
conditions. Sentinel lymph node biopsy (SLB or SLN biopsy) allows selective, minimally invasive access for assessment of the regional lymph node status with
Indocyanine_green
Spread of cancer to the lymph nodes
Lymph node metastasis is the spread (metastasis) of cancer cells into a lymph node. Lymph node metastasis is different from lymphoma. Lymphoma is a cancer
Lymph_node_metastasis
Medical diagnostic method
Lymph node biopsy is a test in which a lymph node or a piece of a lymph node is removed for examination under a microscope (see: biopsy). The lymphatic
Lymph_node_biopsy
Surgical removal of lymph nodes
Lymphadenectomy, or lymph node dissection, is the surgical removal of one or more groups of lymph nodes. It is almost always performed as part of the
Lymphadenectomy
Lymph nodes in the human groin
superficial inguinal lymph nodes and deep inguinal lymph nodes. The superficial inguinal lymph nodes are the inguinal lymph nodes that form a chain immediately
Inguinal_lymph_nodes
Sentinel lymph node of the gall bladder
Calot's node) is the sentinel lymph node of the gall bladder. It is located within the cystohepatic triangle (Calot's triangle). The cystic lymph node is situated
Cystic_node
Organs in the neck
supraclavicular lymph node. Virchow's nodes take their supply from lymph vessels in the abdominal cavity, and are therefore sentinel lymph nodes of cancer in
Supraclavicular_lymph_nodes
Type of skin cancer
Breslow depth, staging, and sentinel lymph node positivity. Out of these factors, it is believed that sentinel lymph node positivity provides the strongest
Acral_lentiginous_melanoma
Imaging technology
sentinel lymph node. MSOT may provide a non-radioactive, non-invasive alternative for examination of the metastatic status of the sentinel lymph node. Initial
Multispectral optoacoustic tomography
Multispectral_optoacoustic_tomography
Limited surgical removal of breast tissue
cancerous cells are very close to the margin. Sentinel lymph node biopsy (SLNB) or axillary lymph node dissection (ALND) may be used to determine if the
Lumpectomy
Pre-cancerous breast lesion
Tan JC, McCready DR, Easson AM, Leong WL (February 2007). "Role of sentinel lymph node biopsy in ductal carcinoma-in-situ treated by mastectomy". Annals
Ductal_carcinoma_in_situ
American surgical oncologist
that if the sentinel lymph node is negative, formal axillary lymph node dissection can be safely avoided. The concept of sentinel lymph node biopsy was
Armando_E._Giuliano
Lymph nodes found in the neck
Cervical lymph nodes are lymph nodes found in the neck. Of the 800 lymph nodes in the human body, 300 are in the neck. Cervical lymph nodes are subject
Cervical_lymph_nodes
Malignant tumor of oil glands in the skin
regional lymph nodes, with adjuvant radiotherapy. There has been no evidence of decreased mortality in those who had SLNB identified lymph node involvement
Sebaceous_carcinoma
Medical diagnostic method
injection of a radionuclide to locate sentinel lymph nodes by their radioactivity. It is used primarily for sentinel lymph node mapping and parathyroid surgery
Gamma_probe
Organ of the lymphatic system
A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked
Lymph_node
Organs of the immune system
at the time of a thyroidectomy as a sentinel lymph node in order to identify risks of cancer spread. "Delphian node". Retrieved 19 January 2016. v t e
Prelaryngeal_lymph_nodes
Topics referred to by the same term
Foundation Animal sentinels, animals which give early indications to environmental hazards Sentinel lymph node, the first lymph node affected by a metastasising
Sentinel
Medical condition
breast cancer. Biopsy of the sentinel lymph node (i.e. armpit lymph node closest to the tumor) or multiple other lymph nodes located in this armpit as well
Male_breast_cancer
Anatomical region of the thigh
positive sentinel lymph node biopsy, generally only the superficial nodes are removed, unless Cloquet's node (the most superior of the deep nodes) is clinically
Femoral_triangle
American oncologist (1934–2014)
an American surgical oncologist who was best known for developing sentinel lymph node evaluation, a procedure that, by some estimates, saves the U.S. healthcare
Donald_Morton
Overview of current and historical management methods of breast cancer
as the removal of this many lymph nodes affected lymphatic drainage. More recently, the technique of sentinel lymph node (SLN) dissection has become popular
Breast_cancer_management
Overview of health effects resulting from tattooing
detect a sentinel lymph node, so existing tattoo pigments in lymph nodes may cause difficulty in identifying and treating sentinel nodes. Lymph nodes may become
Health_effects_of_tattoos
American surgery professor
has specialized in sentinel-node biopsy, a diagnostic method that determines cancer stages based on spread to regional lymph nodes, nipple sparing mastectomy
Elisa_Rush_Port
Cancer that originates in mammary glands
nearest lymph node removed in a procedure called sentinel lymph node biopsy. Dye is injected near the tumor site, and several hours later, the lymph node in
Breast_cancer
Spreading of a disease inside a body
least one lymph node near a tumor site when carrying out surgery to examine or remove a tumor. This lymph node is then called a sentinel lymph node. Lymphatic
Metastasis
Surgical removal of one or both breasts
axillary contents are undisturbed. Sometimes the "sentinel lymph node"—that is, the first axillary lymph node that the metastasizing cancer cells would be
Mastectomy
Area of the human body beneath the joint between arm and torso
Alessandro; Mariuzzi, Laura; Risaliti, Andrea (January 2019). "Sentinel lymph node biopsy in patients affected by breast ductal carcinoma in situ with
Axilla
Group of diseases involving cell growth
(blood-forming) cells that leave the marrow and tend to mature in the lymph nodes and blood, respectively. Germ cell tumor: Cancers derived from pluripotent
Cancer
Rare form of breast cancer
evidencing lymph node metastases. This study did not have patients who presented with metastasis to tissues beyond their sentinel lymph nodes. In a review
Mammary_secretory_carcinoma
Small collection of cancer cells that has spread to another part of the body
micrometastases to the sentinel lymph node is poorer than that of women who do not have any evidence of tumor in these lymph nodes. The same applies to
Micrometastasis
sensitive and specific for detection of breast cancer metastasis to sentinel lymph nodes. It may cross-react with GFAP, leading to aberrant staining of glial
AE1/AE3
Cancer involving the vulva
secondary to dissected lymph nodes. Sentinel lymph node (SLN) dissection is a technique used to identify the main lymph node(s) draining the tumor. The
Vulvar_cancer
Medical diagnostic method
Committee on Cancer Staging Criteria Accurately Predict Sentinel Lymph Node Positivity in Clinically Node-Negative Melanoma Patients". Annals of Surgical Oncology
Breslow's_depth
Lymphatic plexus of the breast
2008). "The Lymphatic Anatomy of the Breast and its Implications for Sentinel Lymph Node Biopsy: A Human Cadaver Study". Annals of Surgical Oncology. 15 (3):
Subareolar_lymphatic_plexus
Metastable nuclear isomer of technetium-99
Content last modified May 2009 Gershenwald JE, Ross MI (5 May 2011). "Sentinel-Lymph-Node Biopsy for Cutaneous Melanoma". New England Journal of Medicine.
Technetium-99m
Surgical rebuilding of a breast
07.015. PMID 26499053. Mannu GS, Navi A, Hussien M (June 2015). "Sentinel lymph node biopsy before mastectomy and immediate breast reconstruction does
Breast_reconstruction
Pharmaceutical drug
intraoperative management; and guiding sentinel lymph node biopsy using a handheld gamma counter in people with clinically node negative squamous cell carcinoma
Technetium (99mTc) tilmanocept
Technetium_(99mTc)_tilmanocept
Medical condition
health concerns prior to surgery, performing sentinel lymph node biopsy over a more extensive axillary lymph node dissection, and properly controlling perioperative
Post-mastectomy_pain_syndrome
British nedical device manufacturer
the lymph nodes draining the primary tumour, the so-called ‘sentinel’ nodes. These can then be detected and excised during a sentinel lymph node biopsy
Endomag
Indian robotic surgeon
Peritoneal Surface Malignancy in India. Performed earliest & popularized Sentinel lymph node biopsy procedure in India. First in India to initiate Robotic Scarless
Somashekhar_SP
Medical specialty
cholecystitis and gallbladder dysfunction, lymphoscintigraphy for sentinel lymph node biopsy, parathyroid imaging for hyperparathyroidism, pulmonary perfusion
Nuclear_medicine_physician
Imaging molecules within living patients
alternatives to quantum dots for intraoperative near-infrared fluorescent sentinel lymph node mapping". Molecular Imaging. 4 (3) 15353500200505127: 172–81. doi:10
Molecular_imaging
Rare and highly aggressive skin cancer
metastatic small cell lung cancer. Once an MCC diagnosis is made, a sentinel lymph node biopsy as well as imaging are recommended as a part of the staging
Merkel-cell_carcinoma
Tumor cell
that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells. Cell division is a normal process used by the body
Cancer_cell
Breast surgical oncologist
McMasters, for the University of Louisville Breast Sentinel Lymph Node Study, “Prediction of Sentinel Lymph Node-Only Disease in Women With Invasive Breast Cancer”
Souzan_El-Eid
Ink used for tattoos
to detect a sentinel lymph node, so existing tattoo pigments in lymph nodes may cause difficulty in identifying and treating sentinel nodes. In rare cases
Tattoo_ink
Surgical procedure that incises the axilla
cancer. The lymph nodes located in the axilla area that are affected by breast cancer are called the guardian or sentinel lymph nodes. Lymph nodes are essential
Axillary_dissection
Blue dye also used as a medication
methylene blue is readily released into the urine. In surgeries such as sentinel lymph node dissections, methylene blue can be used to visually trace the lymphatic
Methylene_blue
Medical condition
prognosis factors for nodular melanoma include: Thickness Ulceration Sentinel lymph node (SLN) status Melanoma Polypoid melanoma DE, Elder; D, Massi; RA,
Nodular_melanoma
Melanoma Gene Expression Profile
melanoma patients at low-risk for nodal metastasis who may forgo the sentinel lymph node biopsy (SLNB) procedure. The CP-GEP model was developed by the Mayo
CP-GEP
Reversal of disease symptoms
"Association of Histologic Regression in Primary Melanoma With Sentinel Lymph Node Status". JAMA Dermatology. 151 (12): 1301–1307. doi:10.1001/jamadermatol
Regression_(medicine)
Upward spreading of abnormal cells in the epidermis
options include: Surgical excision: wide excision with margin control. Sentinel lymph node biopsy: performed in invasive cases to assess metastasis. Immunotherapy:
Pagetoid
US nonprofit organization
in a variety of ways. His research also has discovered alternate sentinel lymph node mapping possibilities and opportunities to avoid axillary dissection
Uschi Keszler's Pennies-in-Action Cancer Research Fund
Uschi_Keszler's_Pennies-in-Action_Cancer_Research_Fund
Part of the female reproductive tract
vaginal lymph nodes reduces the risk of complications that can accompany more radical surgeries. These selective nodes act as sentinel lymph nodes. Instead
Vagina
Metal-free biologically compatible quantum dots with photoluminescence
Prasad, Paras N. (2010-12-07). "In Vivo Targeted Cancer Imaging, Sentinel Lymph Node Mapping and Multi-Channel Imaging with Biocompatible Silicon Nanocrystals"
Silicon_quantum_dot
Pharynx cancer that is located in the oropharynx
oropharynx. Any size and has spread to only one lymph node on the same side of the neck as the cancer. The lymph node with cancer is 30 mm or smaller. Cancer
Oropharyngeal_cancer
Uterine cancer that is located in tissues lining the uterus
distant metastases, making comprehensive surgical staging necessary.Sentinel lymph node biopsy (SLNB) has been incorporated into endometrial cancer staging
Endometrial_cancer
British breast cancer trial
radioisotope and blue dye are used to locate the sentinel nodes. Hiram S Cody (2003). Sentinel Lymph Node Biopsy. Informa Health Care. p. 237. ISBN 1-84184-034-3
ALMANAC
Hospital in ACT, Australia
Bruce was among the earliest institutions in Australia to undertake sentinel lymph node biopsy procedures under the guidance of prominent local breast cancer
North_Canberra_Hospital
Cancer Remedy
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Cancer_rehabilitation
Genetic changes leading to uncontrolled cell growth and tumor formation
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Causes_of_cancer
Cancer capable of infecting other individuals
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Clonally_transmissible_cancer
Medical classification system
internal mammary nodes; and/or in clinically negative internal mammary nodes with micrometastasis, or macrometastasis on sentinel lymph node biopsy. N1mi:
Breast_cancer_classification
Surgical operation
indicated if one or two sentinel lymph nodes are found to have cancer which is not extensive. In this case, the sentinel lymph nodes would be examined, and
Breast-conserving_surgery
Medical condition
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Sacrococcygeal_teratoma
Medical intervention
detect sentinel lymph nodes during surgery. ICG has the main advantage of absorbing and emitting light in the near infrared, allowing detection of nodes under
Fluorescence image-guided surgery
Fluorescence_image-guided_surgery
semiparasitic – semustine – senile keratosis – sentinel lymph node – sentinel lymph node biopsy – sentinel lymph node mapping – seocalcitol – SERM – serotonin
Index_of_oncology_articles
American surgical oncologist
A. L.; Showalter, S.; Brill, K. L.; Copit, S. (2007). "Timing of sentinel lymph node biopsy and reconstruction for patients undergoing mastectomy". Annals
Anne_Rosenberg
Taking measures to decrease cancer incidence
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Cancer_prevention
Protein-coding gene in humans
(1999). "Detection of melanoma micrometastases in the sentinel lymph node and in nonsentinel nodes by tyrosinase polymerase chain reaction". J. Invest.
PMEL_(gene)
Medication derived from poppyseed oil and iodine often used as a contrast agent
S2CID 40066693. Cabanas RM (2000). "The Concept of the Sentinel Lymph Node". Lymphatic Metastasis and Sentinel Lymphonodectomy. Recent Results in Cancer Research
Iodized_oil
Medical condition
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Signs_and_symptoms_of_cancer
Medical intervention
cancer often spreads to nearby lymph nodes in the early stages, especially the sentinel lymph node. Removal of select lymph nodes in the pelvis allows microscopic
Radical retropubic prostatectomy
Radical_retropubic_prostatectomy
Medical term
staging, lymph node spreading status, and metastasis. Large tumor, late staging, presence of cancer cells in multiple distant lymph nodes, and observation
Prognosis_marker
Rare forms of the breast cancer
1% of EPC tumors had spread to nearby axillary lymph nodes at presentation, sentinel axillary lymph node biopsies have sometimes been added to surgical
Papillary carcinomas of the breast
Papillary_carcinomas_of_the_breast
Medical condition
tendency to develop local recurrences and metastasis thereafter to regional lymph nodes, lung, bone, brain, and other locations. Generally speaking, epithelioid
Epithelioid_sarcoma
Rare form of cancer
(2020). "Primary Cutaneous Clear Cell Sarcoma, Clinical Outcome With Sentinel Lymph Nodes Status". Am J Clin Pathol. 153 (5): 799–810. doi:10.1093/ajcp/aqaa009
Clear_cell_sarcoma
American surgeon
D.S. (2001). Radioguidance for nonpalpable primary lesions and sentinel lymph node(s). The American Journal of Surgery, 182(4), pp. 404–406. Gray, R
Emilia_Dauway
Medical condition
prognosis is poor and the most important risk factor is the presence of lymph node metastases. This cancer most often develops on the lowest third of the
Vaginal_melanoma
Gynecologic oncologist
Levine, Douglas A.; Leitao, Mario M. (2014-05-01). "Detection of sentinel lymph nodes in minimally invasive surgery using indocyanine green and near-infrared
Carol_Brown_(physician)
Medical condition
than 2 mm be removed with 2 cm margins. It is advised to have a sentinel lymph node biopsy for lesions that are thicker or have high-risk characteristics
Amelanotic_melanoma
Italian oncologist and politician (1925–2016)
techniques, including sentinel lymph node biopsy, which resulted in axillary dissection in breast cancer with clinically negative lymph nodes no longer being
Umberto_Veronesi
Monoclonal antibody for melanomas
(2002). "Diagnostic Value of HMB-45 and Anti-Melan a Staining of Sentinel Lymph Nodes with Isolated Positive Cells". Modern Pathology. 15 (12): 1288–1293
HMB-45
Sendai virus, virus of rodents
Tanaka S, Miyagawa Y, Suzuki H, Kamide D, et al. (August 2019). "Sentinel Lymph Node-Targeted Therapy by Oncolytic Sendai Virus Suppresses Micrometastasis
Murine_respirovirus
Protein-coding gene in humans
Gradilone A (December 2010). "CD133 and ABCB5 as stem cell markers on sentinel lymph node from melanoma patients". European Journal of Surgical Oncology. 36
ABCB5
Malignant thyroid neoplasm originating from C-cells
for second operation to clean out residual diseased lymph nodes left behind if the sentinel node biopsy was positive for cancerous spread. Extensive surgery
Medullary_thyroid_cancer
Medical condition
pain, or rapid growth; b) are accompanied by enlarged sentinel lymph nodes, i.e. lymph nodes draining the tumor site; c) consist of poorly differentiated
Porocarcinoma
Cancer of the lining of the lips, mouth, or upper throat
fine needle aspiration, biopsy of lymph nodes, and sentinel node biopsy. When the cancer has spread to lymph nodes, their exact location, size, and spread
Oral_cancer
GC. Ultrasound-guided percutaneous axillary lymph node core biopsy: how often is the sentinel lymph node being biopsied? The Breast 2009; 18(1): 13-16
Gordon_Wishart
Medical condition
progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck oral oropharyngeal laryngeal nasopharyngeal
Invasive_urothelial_carcinoma
Rapid histological sectioning procedure
margins. In a sentinel node procedure, a sentinel node containing tumor tissue prompts a further lymph node dissection, while a benign node will avoid such
Frozen_section_procedure
American researcher
Giuliano and others advocated for sentinel node biopsy (SNB) as the preferred option over routine axillary lymph node dissection (ALND) for early-stage
Gary_Herbert_Lyman
MeSH E01.370.388.100.160 – conization MeSH E01.370.388.100.580 – sentinel lymph node biopsy MeSH E01.370.388.250 – endoscopy MeSH E01.370.388.250.035
List_of_MeSH_codes_(E01)
small lymphocytic lymphoma SLN sublingual nitroglycerin SLN SLNB sentinel lymph node biopsy SLP speech-language pathologist SLR straight leg raise (see
List of medical abbreviations: S
List_of_medical_abbreviations:_S
Protein-coding gene in the species Homo sapiens
protective effect of mature DC-LAMP+ dendritic cell accumulation in sentinel lymph nodes containing micrometastatic melanoma". Clin. Cancer Res. 13 (13):
LAMP3
Protein-coding gene in the species Homo sapiens
genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes". Am. J. Clin. Pathol. 121 (5): 637–43. doi:10.1309/MMAC-TXT5-5L8Q-TKC1
Mammaglobin-A
SENTINEL LYMPH-NODE
SENTINEL LYMPH-NODE
Girl/Female
Greek
A nymph.
Girl/Female
Latin Greek
A nymph.
Girl/Female
Latin American Hawaiian
A nymph.
Girl/Female
Greek
A nymph.
Girl/Female
Latin
A nymph.
Girl/Female
Polish
Wood nymph.
Girl/Female
Greek Latin
Nymph.
Girl/Female
Latin Spanish
A nymph.
Girl/Female
Latin
A nymph.
Girl/Female
Indian
A nymph
Girl/Female
Latin American
A nymph.
Boy/Male
Australian, Jamaican
Sentinel; Guard
Girl/Female
Latin
A nymph.
Girl/Female
Latin
A nymph.
Girl/Female
Latin
A nymph.
Girl/Female
Latin
A nymph.
Girl/Female
Arabic, Australian, French, Greek, Latin, Muslim
Flowing; Nymph; Water Nymph; River Nymph
Girl/Female
Muslim
A nymph
Girl/Female
Latin
A nymph.
Girl/Female
Latin American Greek
A nymph.
SENTINEL LYMPH-NODE
SENTINEL LYMPH-NODE
Male
Hebrew
(×ֵלִיָּה) Hebrew name ELIYAH means "the Lord is my God." In the bible, this is the name of several characters, including the prophet who lived during the reign of Ahab.
Boy/Male
Indian, Punjabi, Sikh
Happy Young Person
Girl/Female
Hindu, Indian, Malayalam, Marathi, Sanskrit
Well Born
Girl/Female
Irish
The feminine of the name Aidan meaning “little fire.â€
Boy/Male
Tamil
Autumn, Super boy, Complete or meaningful
Boy/Male
Hindu, Indian
One who Serves Guru
Boy/Male
Tamil
Uma Shankar | உமா ஷஂகரÂ
Indicates both names of Shiva and Shivani
Girl/Female
Indian, Marathi, Traditional
A God of Music; God of Singing; Feeling about Music
Boy/Male
Indian
Fragrance; Smell; Perfume
Surname or Lastname
English
English : variant spelling of Hillman.
SENTINEL LYMPH-NODE
SENTINEL LYMPH-NODE
SENTINEL LYMPH-NODE
SENTINEL LYMPH-NODE
SENTINEL LYMPH-NODE
n.
A sea nymph.
v. t.
To furnish with a sentinel; to place under the guard of a sentinel or sentinels.
n.
A marine crab (Podophthalmus vigil) native of the Indian Ocean, remarkable for the great length of its eyestalks; -- called also sentinel crab.
v. t.
To watch over like a sentinel.
n.
Watch; guard.
a.
Having a faculty, or faculties, of sensation and perception. Specif. (Physiol.), especially sensitive; as, the sentient extremities of nerves, which terminate in the various organs or tissues.
n.
A fibrinous material exuded from the blood vessels in inflammation. In the process of healing it is either absorbed, or is converted into connective tissue binding the inflamed surfaces together.
n.
One who has the faculty of perception; a sentient being.
p. pr. & vb. n.
of Sentinel
n.
One who watches or guards; specifically (Mil.), a soldier set to guard an army, camp, or other place, from surprise, to observe the approach of danger, and give notice of it; a sentry.
n.
Sentinel.
n.
Lenticel.
a.
Containing, or like, lymph.
imp. & p. p.
of Sentinel
a.
pertaining to, containing, or conveying lymph.
n.
A water nymph.
n.
A soldier placed on guard; a sentinel.
n.
Guard; watch, as by a sentinel.