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ROSA26

  • ROSA26

    • ROSA26 is a locus used for constitutive, ubiquitous gene expression in mice. It was first isolated in 1991 by the group of Philippe Soriano in a gene-trap

    ROSA26

    ROSA26

  • Gene knock-in

    • Genetic engineering technique

    random integration of the donor template. Also, only a few loci, such as the ROSA26 locus have been characterized well enough where they can be used for conditional

    Gene knock-in

    Gene_knock-in

  • Stem cell marker

    • antibody antithrombin III (AT) asialo GM1 Bcl-2 Beta-galactosidase (β-gal) of ROSA26 mice beta1-integrin bromodeoxyuridine c-kit (CD117) c-Met C1qR(p) END (CD105)

    Stem cell marker

    Stem_cell_marker

  • Mouse models of breast cancer metastasis

    • Cancer research

    reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus". BMC Developmental Biology. 1 4. doi:10.1186/1471-213X-1-4. PMC 31338

    Mouse models of breast cancer metastasis

    Mouse_models_of_breast_cancer_metastasis

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ROSA26

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